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    Aminotriazole compounds
    1.
    发明授权
    Aminotriazole compounds 失效
    氨基三唑化合物

    公开(公告)号：US06245916B1

    公开(公告)日：2001-06-12

    申请号：US09549745

    申请日：2000-04-14

    申请人： Jean-Luc Fauchere ,  Jean-Claude Ortuno ,  Jacques Duhault ,  Jean Albert Boutin ,  Nigel Levens

    发明人： Jean-Luc Fauchere ,  Jean-Claude Ortuno ,  Jacques Duhault ,  Jean Albert Boutin ,  Nigel Levens

    IPC分类号： C07D24912

    CPC分类号： C07D401/12 ,  C07D249/14 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  Y02P20/55

    摘要： Compound of formula (I): wherein: n is 0 or 1, W represents —CO— or S(O)q and q is 0, 1 or 2, G represents a G1, G2, G3 or G4 group as defined in the description, Z represents alkyl, aryl, heteroaryl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylalkenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted. A represents a grouping selected from —A2—, —A1—A2—, —A2—A1— and —A1—A2—A1— wherein A1 is alkylene and A2 represents phenylene, cycloalkylene, naphthylene or heteroarylene each optionally substituted, R represents hydrogen, alkyl, aryl, heteroaryl, arylalkyl arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkenyl each optionally substituted, R1 represents alkyl, aryl, heteroary, arylalkyl arylalkenyl, arylalkynyl, heteroarylalkenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, and medicinal products containing the same which are useful as Neuropeptide Y receptor ligands.

    摘要翻译： 式（I）化合物：其中：n为0或1，W表示-CO-或S（O）q，q为0,1或2，G表示如上述定义的G1，G2，G3或G4基团 描述，Z代表烷基，芳基，杂芳基，芳基烷基，芳基烯基，芳基炔基，杂芳基烯基，杂芳基炔基或杂芳基烷基，各自任选取代.A代表选自-A2-，-A1-A2-，-A2-A1-和-A1- 其中A1是亚烷基，A2代表亚苯基，亚环烷基，亚萘基或亚杂芳基，各自任选取代，R代表氢，烷基，芳基，杂芳基，芳基烷基芳基烯基，芳基炔基，杂芳基酰基，杂芳基炔基或杂芳基烯基， 芳基，芳基烷基芳基烯基，芳基炔基，杂芳基烯基，杂芳基炔基或各自任意取代的杂芳基烷基，以及含有该芳基的可药用神经肽Y受体配体的医药产品。

    Aminotriazole compounds
    2.
    发明授权
    Aminotriazole compounds 失效
    氨基三唑化合物

    公开(公告)号：US06596749B2

    公开(公告)日：2003-07-22

    申请号：US09799199

    申请日：2001-03-05

    申请人： Jean-Luc Fauchere ,  Jean-Claude Ortuno ,  Jacques Duhault ,  Jean Albert Boutin ,  Nigel Levens

    发明人： Jean-Luc Fauchere ,  Jean-Claude Ortuno ,  Jacques Duhault ,  Jean Albert Boutin ,  Nigel Levens

    IPC分类号： A61K314196

    CPC分类号： C07D401/12 ,  C07D249/14 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  Y02P20/55

    摘要： Method of treating with compounds of formula (I): wherein: n is 0 or 1, W represents —CO— or S(O)q and q is 0, 1 or 2, G represents a G1, G2, G3 or G4 group as defined in the description, Z represents alkyl, aryl, heteroaryl, arylalkyl, arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, A represents a grouping selected from —A2—, —A1—A2—, —A2—A1—, and —A1—A2—A1— wherein A1 is alkylene and A2 represents phenylene, cycloalkylene, naphthylene or heteroarylene each optionally substituted, R represents hydrogen, alkyl, aryl, heteroaryl, arylalkyl arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, R1 represents alkyl, aryl, heteroaryl, arylalkyl arylalkenyl, arylalkynyl, heteroarylakenyl, heteroarylalkynyl or heteroarylalkyl each optionally substituted, and medicinal products containing the same are useful as Neuropeptide Y receptor ligands.

    摘要翻译： 用式（I）化合物处理的方法：其中：n为0或1，W为-CO-或S（O）q，q为0,1或2，G为G1，G2，G3或G4基团 Z表示烷基，芳基，杂芳基，芳基烷基，芳基烯基，芳基炔基，杂芳基酰基，杂芳基炔基或杂芳基烷基，各自任选取代，A表示选自-A2-，-A1-A2-，-A2-A1- 和-A1-A2-A1-，其中A1是亚烷基，A2代表亚苯基，亚环烷基，亚萘基或亚杂芳基，各自任选取代，R表示氢，烷基，芳基，杂芳基，芳基烷基芳基烯基，芳基炔基，杂芳基酰基，杂芳基炔基或杂芳基烷基， R 1表示烷基，芳基，杂芳基，芳基烷基芳基烯基，芳基炔基，杂芳基酰基，杂芳基炔基或杂芳基烷基，各自任选被取代，并且含有它们的医药产品可用作神经肽Y受体配体。