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公开(公告)号：US5804184A
公开(公告)日：1998-09-08
申请号：US812025
申请日：1997-03-06
申请人： Jurgen Logemann , Guido Jach , Birgit Gornhardt , John Mundy , Jeff Schell , Peter Eckes
发明人： Jurgen Logemann , Guido Jach , Birgit Gornhardt , John Mundy , Jeff Schell , Peter Eckes
IPC分类号： A01H5/00 , C07K14/37 , C07K14/415 , C12N9/24 , C12N15/82 , A61K38/54 , A61K38/16 , A61K38/47
CPC分类号： C12Y302/01014 , C07K14/37 , C07K14/415 , C12N15/8282 , C12N9/2402 , C12N9/2442 , Y10S47/01
摘要： Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).
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公开(公告)号：US5689045A
公开(公告)日：1997-11-18
申请号：US457797
申请日：1995-06-01
申请人： Jurgen Logemann , Guido Jach , Birgit Gornhardt , John Mundy , Jeff Schell , Peter Eckes , Ilan Chet
发明人： Jurgen Logemann , Guido Jach , Birgit Gornhardt , John Mundy , Jeff Schell , Peter Eckes , Ilan Chet
CPC分类号： C12Y302/01014 , C07K14/37 , C07K14/415 , C12N15/8282 , C12N9/2402 , C12N9/2442 , Y10S47/01
摘要： Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).
摘要翻译： 转基因病原体抗性生物体，其基因组含有至少两种不同基因，在活性启动子控制下具有病原体抑制作用。 该生物体的特征在于协同的病原体抑制作用。 当基因编码基因产物几丁质酶（ChiS，ChiG），葡聚糖酶（GluG），蛋白质合成抑制剂（PSI）和抗真菌蛋白质（AFP））时，这种作用是显而易见的。
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公开(公告)号：US5633442A
公开(公告)日：1997-05-27
申请号：US375186
申请日：1995-01-18
申请人： Jeff Schell , Jurgen Logemann , Guido Jach , John Mundy
发明人： Jeff Schell , Jurgen Logemann , Guido Jach , John Mundy
IPC分类号： A01H5/00 , A01N63/00 , A61K38/16 , C07K14/415 , C12N5/10 , C12N9/24 , C12N15/09 , C12N15/29 , C12N15/82 , A01H1/00 , C12P1/04
CPC分类号： C12Y302/01039 , C07K14/415 , C12N15/8282 , C12N9/2402 , C12N9/2442 , C12Y302/01014
摘要： Described are a method of producing pathogen-resistant plants in which a protein-synthesis inhibitor gene or a fusion product of the protein-synthesis inhibitor gene or of the protein-synthesis inhibitor protein with ligands permitting specific attachment to cells is introduced into the genotype of plants under the control of an active promotor, and the use of the protein-synthesis inhibitor protein obtained by introducing the protein-synthesis inhibitor gene into the bacterial overproducers for making pharmaceutical preparations.
摘要翻译： 描述了一种生产病原体抗性植物的方法，其中将蛋白质合成抑制剂基因或蛋白质合成抑制剂基因或蛋白质合成抑制剂蛋白质的融合产物与允许特异性附着于细胞的配体引入基因型 在活性启动子控制下的植物，以及通过将蛋白质合成抑制剂基因导入用于制备药物制剂的细菌过量产生而获得的蛋白质合成抑制剂蛋白质的用途。
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公开(公告)号：USRE39238E1
公开(公告)日：2006-08-15
申请号：US09729141
申请日：2000-12-01
申请人： Jürgen Logemann , Guido Jach , Birgit Görnhardt , John Mundy , Jeff Schell , Peter Eckes , Ilan Chet
发明人： Jürgen Logemann , Guido Jach , Birgit Görnhardt , John Mundy , Jeff Schell , Peter Eckes , Ilan Chet
CPC分类号： C07K14/37 , C07K14/415 , C12N9/24 , C12N15/8282 , C12Y302/01014
摘要： Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinase (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFP).
摘要翻译： 转基因病原体抗性生物体，其基因组含有至少两种不同基因，在活性启动子控制下具有病原体抑制作用。 该生物体的特征在于协同的病原体抑制作用。 当基因编码基因产物几丁质酶（ChiS，ChiG），葡聚糖酶（GluG），蛋白质合成抑制剂（PSI）和抗真菌蛋白质（AFP））时，这种作用是显而易见的。
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公开(公告)号：US06271442B1
公开(公告)日：2001-08-07
申请号：US08775362
申请日：1997-01-03
申请人： Jeff Schell , Jürgen Logemann , Guido Jach , John Mundy
发明人： Jeff Schell , Jürgen Logemann , Guido Jach , John Mundy
IPC分类号： C12N1500
CPC分类号： C12Y302/01039 , C07K14/415 , C12N9/2402 , C12N9/2442 , C12N15/8282 , C12Y302/01014
摘要： Described are a method of producing pathogen-resistant plants in which a protein-synthesis inhibitor gene or a fusion product of the protein-synthesis inhibitor gene or of the protein-synthesis inhibitor protein with ligands permitting specific attachment to cells is introduced into the genotype of plants under the control of an active promotor, and the use of the protein-synthesis inhibitor protein obtained by introducing the protein-synthesis inhibitor gene into the bacterial overproducers for making pharmaceutical preparations.
摘要翻译： 描述了一种生产病原体抗性植物的方法，其中将蛋白质合成抑制剂基因或蛋白质合成抑制剂基因或蛋白质合成抑制剂蛋白质的融合产物与允许特异性附着于细胞的配体引入基因型 在活性启动子控制下的植物，以及通过将蛋白质合成抑制剂基因导入用于制备药物制剂的细菌过量产生而获得的蛋白质合成抑制剂蛋白质的使用。
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公开(公告)号：US06271438B1
公开(公告)日：2001-08-07
申请号：US09138873
申请日：1998-08-24
申请人： Jürgen Logemann , Guido Jach , Birgit Görnhardt , John Mundy , Jeff Schell , Peter Eckes , Ilan Chet
发明人： Jürgen Logemann , Guido Jach , Birgit Görnhardt , John Mundy , Jeff Schell , Peter Eckes , Ilan Chet
IPC分类号： A01H106
CPC分类号： C12Y302/01014 , C07K14/37 , C07K14/415 , C12N9/2402 , C12N9/2442 , C12N15/8282 , Y10S47/01
摘要： Transgenic pathogen-resistant organism whose genome contains at least two different genes under the control of active promoters with pathogen-inhibiting action. This organism is distinguished by a synergistic pathogen-inhibiting action. This action is evident particularly when the genes code for the gene products chitinese (ChiS, ChiG), glucanase (GluG), protein synthesis inhibitor (PSI) and antifungal protein (AFR).
摘要翻译： 转基因病原体抗性生物体，其基因组含有至少两种不同基因，在活性启动子控制下具有病原体抑制作用。 该生物体的特征在于协同的病原体抑制作用。 当基因编码chitinese（ChiS，ChiG），葡聚糖酶（GluG），蛋白质合成抑制剂（PSI）和抗真菌蛋白质（AFR））的基因时，这一行动是显而易见的。
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7.发明授权ω-Aminocarboxylic acids, ω-aminocarboxylic acid esters, or recombinant cells which produce lactams thereof 有权ω-氨基羧酸，ω-氨基羧酸酯或产生其内酰胺的重组细胞公开(公告)号：US09012227B2
公开(公告)日：2015-04-21
申请号：US12742318
申请日：2008-12-12
申请人： Andreas Karau , Volker Sieber , Thomas Haas , Harald Haeger , Katrin Grammann , Bruno Buehler , Lars Blank , Andreas Schmid , Guido Jach , Bernd Lalla , Andreas Mueller , Katrin Schullehner , Peter Welters , Thorsten Eggert , Andrea Weckbecker
发明人： Andreas Karau , Volker Sieber , Thomas Haas , Harald Haeger , Katrin Grammann , Bruno Buehler , Lars Blank , Andreas Schmid , Guido Jach , Bernd Lalla , Andreas Mueller , Katrin Schullehner , Peter Welters , Thorsten Eggert , Andrea Weckbecker
CPC分类号： C12N15/52 , C08G69/08 , C08G69/14 , C12P13/005
摘要： The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more ω-aminocarboxylic acids, more ω-aminocarboxylic acid esters or more lactams derived from ω-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of ω-aminocarboxylic acids, of ω-aminocarboxylic acid esters or of lactams derived from ω-aminocarboxylic acids, the ω-aminocarboxylic acids, ω-aminocarboxylic acid esters or lactams derived from ω-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on ω-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.
摘要翻译： 本发明涉及一种相对于其野生型经遗传修饰的细胞，因此与野生型相比，能够产生更多的ω-氨基羧酸，更多的ω-氨基羧酸酯或更多来源于ω的内酰胺 氨基羧酸，起始于羧酸或羧酸酯。 此外，本发明涉及生产转基因细胞的方法，可通过该方法获得的细胞，ω-氨基羧酸酯或ω-氨基羧酸衍生的内酰胺的生产ω-氨基羧酸的方法 酸，ω-氨基羧酸，ω-氨基羧酸酯或衍生自可通过该方法得到的ω-氨基羧酸的内酰胺，制备基于ω-氨基羧酸或基于内酰胺的聚酰胺的方法和可通过该方法获得的聚酰胺 。
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8.发明申请OMEGA-AMINO CARBOXYLIC ACIDS, OMEGA-AMINO CARBOXYLIC ACID ESTERS, OR RECOMBINANT CELLS WHICH PRODUCE LACTAMS THEREOF 有权欧米加氨基羧酸，欧米加氨基羧酸酯，或其生产其乳酸的重组细胞公开(公告)号：US20100324257A1
公开(公告)日：2010-12-23
申请号：US12742318
申请日：2008-12-12
申请人： Andreas Karau , Volker Sieber , Thomas Haas , Harald Haeger , Katrin Grammann , Bruno Buehler , Lars Blank , Andreas Schmid , Guido Jach , Bernd Lalla , Andreas Mueller , Katrin Schullehner , Peter Welters , Thorsten Eggert , Andrea Weckbecker
发明人： Andreas Karau , Volker Sieber , Thomas Haas , Harald Haeger , Katrin Grammann , Bruno Buehler , Lars Blank , Andreas Schmid , Guido Jach , Bernd Lalla , Andreas Mueller , Katrin Schullehner , Peter Welters , Thorsten Eggert , Andrea Weckbecker
IPC分类号： C08G69/08 , C12N1/00 , C12N1/21 , C12P13/00 , C12P17/10 , C07C229/00 , C07D225/00 , C08G73/06
CPC分类号： C12N15/52 , C08G69/08 , C08G69/14 , C12P13/005
摘要： The present invention relates to a cell, which has been genetically modified relative to its wild type, so that in comparison with its wild type it is able to produce more ω-aminocarboxylic acids, more ω-aminocarboxylic acid esters or more lactams derived from ω-aminocarboxylic acids, starting from carboxylic acids or carboxylic acid esters. Furthermore, the present invention relates to a method for the production of a genetically modified cell, the cells obtainable by this method, a method for the production of ω-aminocarboxylic acids, of ω-aminocarboxylic acid esters or of lactams derived from ω-aminocarboxylic acids, the ω-aminocarboxylic acids, ω-aminocarboxylic acid esters or lactams derived from ω-aminocarboxylic acids obtainable by this method, a method for the production of polyamides based on ω-aminocarboxylic acids or based on lactams and the polyamides obtainable by this method.
摘要翻译： 本发明涉及一种相对于其野生型经遗传修饰的细胞，因此与野生型相比，能够产生更多的ω-氨基羧酸，更多的ω-氨基羧酸酯或更多来源于ω的内酰胺 氨基羧酸，起始于羧酸或羧酸酯。 此外，本发明涉及生产转基因细胞的方法，可通过该方法获得的细胞，ω-氨基羧酸酯或ω-氨基羧酸衍生的内酰胺的生产ω-氨基羧酸的方法 酸，ω-氨基羧酸，ω-氨基羧酸酯或衍生自可通过该方法得到的ω-氨基羧酸的内酰胺，制备基于ω-氨基羧酸或基于内酰胺的聚酰胺的方法和可通过该方法获得的聚酰胺 。
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