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公开(公告)号：US07919136B2
公开(公告)日：2011-04-05
申请号：US11874427
申请日：2007-11-20
IPC分类号： A61L33/00
CPC分类号： C09D133/02 , A61L27/18 , A61L27/34 , A61L27/50 , A61L29/085 , A61L29/14 , A61L31/10 , A61L31/14 , C08J7/047 , C08J2433/00 , G02B1/043 , C08L83/04
摘要： A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising a polymer or copolymer having one or more repeating units of the formula: wherein R independently is a C2-C20 hydrocarbon radical and n is an integer of 2 to 5000.
摘要翻译： 提供了表面改性的生物医学装置，其包括在其至少一部分上具有涂层的生物医学装置，所述涂层包含具有一个或多个下式重复单元的聚合物或共聚物：其中R独立地为C 2 -C 20烃基，n 是2〜5000的整数。
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公开(公告)号：US20110152399A1
公开(公告)日：2011-06-23
申请号：US13036402
申请日：2011-02-28
CPC分类号： C09D133/02 , A61L27/18 , A61L27/34 , A61L27/50 , A61L29/085 , A61L29/14 , A61L31/10 , A61L31/14 , C08J7/047 , C08J2433/00 , G02B1/043 , C08L83/04
摘要： A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising a polymer or copolymer having one or more repeating units of the formula: wherein R independently is a C2-C20 hydrocarbon radical and n is an integer of 2 to 5000.
摘要翻译： 提供了表面改性的生物医学装置，其包括在其至少一部分上具有涂层的生物医学装置，所述涂层包含具有一个或多个下式重复单元的聚合物或共聚物：其中R独立地为C 2 -C 20烃基，n 是2〜5000的整数。
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公开(公告)号：US08100528B2
公开(公告)日：2012-01-24
申请号：US12334619
申请日：2008-12-15
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reacting with complementary surface functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过与沿着聚合物基底的单体单元的互补表面官能团反应的分段嵌段共聚物的相互作用官能团将相互作用的嵌段共聚物连接到基材的表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，其包括由 这样一种方法。
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公开(公告)号：US20090173044A1
公开(公告)日：2009-07-09
申请号：US12258916
申请日：2008-10-27
IPC分类号： B65B55/02
CPC分类号： C11D3/0078 , A45C11/005 , A61L12/04 , B65B25/008 , B65B55/06 , C11D1/82 , C11D17/041 , Y10S514/84
摘要： Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a substantially water-soluble silicone-containing surfactant. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, preventing dryness and improving lubricity.
摘要翻译： 公开了用于存储诸如隐形眼镜的眼科装置的包装系统，以及用于包装这些眼科装置的方法以提供穿戴期间镜片的舒适度的解决方案。 包装系统包括存储在包含基本上水溶性的含硅氧烷表面活性剂的水性包装溶液中的眼科装置。 这种溶液长时间保留在未使用的镜片的表面上，导致眼睛中持续存在的表面改性，这可以显着改善首次使用的新鲜隐形眼镜的润湿性能，此外甚至 镜片插入后数小时，防止干燥，提高润滑性。
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公开(公告)号：US20090171027A1
公开(公告)日：2009-07-02
申请号：US12334615
申请日：2008-12-15
IPC分类号： C08F299/00
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward interactive segmented block copolymers useful to treat the surface of a substrate by means of interactive functionalities of the interactive segmented block copolymer material binding with complementary surface functionalities of the polymer substrate.
摘要翻译： 本发明涉及用于通过与聚合物基质的互补表面官能团结合的相互作用的分段嵌段共聚物材料的相互作用功能来处理基材表面的相互作用的嵌段共聚物。
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6.发明授权公开(公告)号：US08377464B2
公开(公告)日：2013-02-19
申请号：US13405604
申请日：2012-02-27
IPC分类号： A61F2/00
CPC分类号： G02B1/043
摘要： This invention describes the use of polymerizable surfactants as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.
摘要翻译： 本发明描述了可聚合表面活性剂作为共聚单体在形成眼科装置如隐形眼镜，人工晶状体，角膜植入物等中的用途。
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公开(公告)号：US07942929B2
公开(公告)日：2011-05-17
申请号：US12334618
申请日：2008-12-15
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过末端官能化表面活性剂材料与沿聚合物基质的单体单元的互补表面反应性官能团反应的反应性官能团将反应性嵌段共聚物附着到基材表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，包括由 这样一种方法。
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公开(公告)号：US07915323B2
公开(公告)日：2011-03-29
申请号：US12499853
申请日：2009-07-09
IPC分类号： G02B1/04
摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices.
摘要翻译： 本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。 更具体地说，本发明涉及能够聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些单烯属不饱和聚碳硅氧烷单体。
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9.发明申请公开(公告)号：US20090171459A1
公开(公告)日：2009-07-02
申请号：US12334618
申请日：2008-12-15
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过末端官能化表面活性剂材料与沿聚合物基质的单体单元的互补表面反应性官能团反应的反应性官能团将反应性嵌段共聚物附着到基材表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，包括由 这样一种方法。
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公开(公告)号：US20090171049A1
公开(公告)日：2009-07-02
申请号：US12333345
申请日：2008-12-12
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward reactive segmented block copolymers useful to treat the surface of a substrate by means of reactive functionalities of the reactive segmented block copolymer material reacting with complementary surface reactive functionalities of the polymer substrate.
摘要翻译： 本发明涉及用于通过与聚合物基质的互补表面反应性官能团反应的反应性嵌段共聚物材料的反应性官能团来处理基材表面的反应性分段嵌段共聚物。
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