Medical prostheses having bundled and non-bundled regions

    公开(公告)号:US10265200B2

    公开(公告)日:2019-04-23

    申请号:US13814179

    申请日:2010-08-10

    Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

    MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS
    3.
    发明申请
    MEDICAL PROSTHESES HAVING BUNDLED AND NON-BUNDLED REGIONS 审中-公开
    具有组合和非完整区域的医疗前景

    公开(公告)号:US20130211497A1

    公开(公告)日:2013-08-15

    申请号:US13814179

    申请日:2010-08-10

    Abstract: The present embodiments provide an endoluminal prosthesis, such as a stent-graft, having a relatively low delivery profile. In one embodiment, the prosthesis comprises a membrane, and at least one stent having contracted and expanded states, where the stent is coupled to the membrane and maintains patency in the expanded state. The prosthesis further may comprise selectively oriented axial and/or circumferential fibers arranged at predetermined locations along the length and circumference of the prosthesis. An increased population density of the circumferential and/or axial fibers may be provided in areas in which the at least one stent portion is attached to the membrane, or in areas of higher physiological loads imposed upon the endoluminal prosthesis. Selectively orienting axial fibers and circumferential fibers at predetermined locations along the length and circumference of the prosthesis, but not continuously along the entire prosthesis, significantly reduces delivery profile due to the reduction in graft material.

    Abstract translation: 本实施例提供具有相对低的传送轮廓的腔内假体,例如支架移植物。 在一个实施例中,假体包括膜和至少一个具有收缩和扩张状态的支架,其中支架联接到膜并且保持开放状态处于膨胀状态。 假体还可以包括沿着假体的长度和圆周布置在预定位置处的选择性地定向的轴向和/或周向纤维。 圆周和/或轴向纤维的增加的人口密度可以设置在其中至少一个支架部分附接到膜的区域中,或者在施加在内腔假体上的较高生理负荷的区域中。 沿着假体的长度和周长的预定位置选择性地定向轴向纤维和周向纤维,但不是沿着整个假体连续地定向,从而显着减少由于移植材料的减少导致的输送轮廓。

    Method of promoting cell proliferation and ingrowth by injury to the native tissue
    4.
    发明授权
    Method of promoting cell proliferation and ingrowth by injury to the native tissue 有权
    通过损伤天然组织促进细胞增殖和向内生长的方法

    公开(公告)号:US07815687B2

    公开(公告)日:2010-10-19

    申请号:US12337163

    申请日:2008-12-17

    Abstract: The present invention relates to methods of treating tissue of the human body, specially, methods of promoting cell proliferation and ingrowth around implantable medical devices. The methods include inserting an apparatus comprising asperities adapted to injure native tissue at a desired anchoring location, injuring the native tissue at the desired anchoring location with the apparatus to initiate an injury response in the native tissue to thereby promote cell proliferation and ingrowth; and implanting the medical device at the treatment location.

    Abstract translation: 本发明涉及治疗人体组织的方法,特别是促进可植入医疗器械周围的细胞增殖和向内生长的方法。 所述方法包括插入装置,其包括适于在期望的锚固位置处伤害天然组织的凹凸,用设备在期望的锚定位置损伤天然组织以在天然组织中引发损伤反应,从而促进细胞增殖和向内生长; 以及将医疗装置植入治疗位置。

    S-shaped stent design
    5.
    发明授权
    S-shaped stent design 有权
    S形支架设计

    公开(公告)号:US07655033B2

    公开(公告)日:2010-02-02

    申请号:US11297913

    申请日:2005-12-08

    CPC classification number: A61F2/82 A61F2/91 A61F2250/0037 A61F2250/0039

    Abstract: A variable curvature stent limb is disclosed herein. A stent derived from a plurality of these variable curvature stent limbs may be highly compressible, such that it is compatible with a low-profile delivery device. This stent may be useful over a wider range of body vessel diameters and may possess a greater fatigue life, since this stent may provide a more controlled constant radial force.

    Abstract translation: 本文公开了一种可变曲率支架肢体。 衍生自多个这些可变曲率支架肢体的支架可以是高度可压缩的,使得其与低调输送装置兼容。 该支架可以在更宽范围的体血管直径上有用,并且可以具有更大的疲劳寿命,因为该支架可以提供更受控制的恒定径向力。

    Medical device coating process
    7.
    发明授权
    Medical device coating process 有权
    医疗器械涂装工艺

    公开(公告)号:US08231929B2

    公开(公告)日:2012-07-31

    申请号:US11877369

    申请日:2007-10-23

    Applicant: Jichao Sun

    Inventor: Jichao Sun

    Abstract: Methods for coating medical devices for implantation within a body vessel are provided comprising providing a cylindrical container, placing a medical device inside the cylindrical container, and applying a polymer in liquid form inside the container.

    Abstract translation: 提供用于涂覆在体内容器内植入的医疗装置的方法,包括提供圆柱形容器,将医疗装置放置在圆柱形容器内,以及将液体形式的聚合物涂覆在容器内。

    METHODS OF MAKING AN ENDOVASCULAR PROSTHESIS USING A DEFORMABLE MATRIX
    9.
    发明申请
    METHODS OF MAKING AN ENDOVASCULAR PROSTHESIS USING A DEFORMABLE MATRIX 有权
    使用可变矩阵进行血管内皮生长的方法

    公开(公告)号:US20100219562A1

    公开(公告)日:2010-09-02

    申请号:US12598249

    申请日:2008-05-19

    Applicant: Jichao Sun

    Inventor: Jichao Sun

    Abstract: A method of making an endovascular prosthesis comprises the steps of applying a first layer of polymer to a portion of a deformable matrix, contacting a stent with the polymer to deform the matrix, applying a second layer of polymer over at least a portion of the stent and first layer, solidifying the layers of polymer to form the endovascular prosthesis, and removing the matrix.

    Abstract translation: 制造血管内假体的方法包括以下步骤:将第一层聚合物施加到可变形基质的一部分上,使支架与聚合物接触以使基质变形,在支架的至少一部分上施加第二层聚合物 和第一层,固化聚合物层以形成血管内假体,并除去基质。

    Branch vessel stent graft
    10.
    发明申请
    Branch vessel stent graft 有权
    支血管支架移植

    公开(公告)号:US20070010874A1

    公开(公告)日:2007-01-11

    申请号:US11481763

    申请日:2006-07-06

    Applicant: Jichao Sun

    Inventor: Jichao Sun

    Abstract: A stent graft (10) has a tubular body of a biocompatible material and a side arm (20) fastened to the tubular body. A tubular extension piece (24) is sealingly joined to the end of the side arm and extends from it. It can be joined with adhesive or stitching. The extension piece can be formed from an elastomeric biocompatible material such as Thoralon™. The extension piece can have a resilient reinforcement 44 embedded into it and extending longitudinally. The extension piece is tucked back into the side arm during deployment of the stent graft into a body lumen.

    Abstract translation: 支架移植物(10)具有生物相容性材料的管状体和紧固到管状体的侧臂(20)。 管状延伸件(24)密封地连接到侧臂的端部并从其延伸。 它可以粘合或缝合。 延伸件可以由诸如Thoralon TM的弹性生物相容性材料形成。 延伸件可以具有嵌入其中并纵向延伸的弹性加强件44。 在将支架移植物部署到体腔内时,延伸片被折回到侧臂中。

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