公开(公告)号：US09222225B2

公开(公告)日：2015-12-29

申请号：US13994931

申请日：2011-12-15

申请人： Jijun Wang ,  Cheng Jiang ,  Weibin Liu ,  Yong Zhao ,  Meng Wang ,  Ziqing Jiang ,  Jia Fan ,  Xianggang Du ,  Lu Chunfang

发明人： Jijun Wang ,  Cheng Jiang ,  Weibin Liu ,  Yong Zhao ,  Meng Wang ,  Ziqing Jiang ,  Jia Fan ,  Xianggang Du ,  Lu Chunfang

IPC分类号： E01B1/00 ,  E01B3/40

CPC分类号： E01B1/002 ,  E01B3/40

摘要： Provided in the disclosure is a pre-stressed concrete track slab of slab-type ballast-less track, which includes a slab body (1), on which fastening embedded casings (4) are arranged. At least one row of longitudinal common steel bars (11) and at least one row of transverse common steel bars (12) are arranged in the slab body (1) along a length direction and a width direction. The longitudinal common steel bars (11) are insulated from the transverse common steel bars (12). At least one row of longitudinal pre-stressed steel bars (7) and at least one row of transverse pre-stressed steel bars (6) are fastened in the slab body (1) along the length direction and the width direction through anchor backing plates and fastener devices (8). In the pre-stress directions of the longitudinal pre-stressed steel bars (7) and the transverse pre-stressed steel bars (6), it is post-tensioned in both directions or it is pre-tensioned in one direction and post-tensioned in the other direction. Limiting structures (5) and grounding terminals (10) are also arranged on the slab body (1). The pre-stressed concrete track slab has the characteristics of light structural dead weight, small structure height, low manufacturing cost and deformation resistance.

摘要翻译： 本发明公开了一种板坯式无轨道预应力混凝土轨道板，包括板体（1），其上布置有紧固嵌入壳体（4）。 至少一排纵向普通钢筋（11）和至少一排横向普通钢筋（12）沿着长度方向和宽度方向布置在板坯体（1）中。 纵向普通钢筋（11）与横向普通钢筋（12）绝缘。 至少一排纵向预应力钢筋（7）和至少一排横向预应力钢筋（6）沿着长度方向和宽度方向通过锚固衬板（6）紧固在板体（1）中 和紧固件装置（8）。 在纵向预应力钢筋（7）和横向预应力钢筋（6）的预应力方向上，其沿两个方向被后张紧或者在一个方向上被预张紧并且被拉伸 在另一个方向。 限制结构（5）和接地端子（10）也布置在板体（1）上。 预应力混凝土轨道板具有结构自重轻，结构高度小，制造成本低，抗变形的特点。

公开(公告)号：US09758932B2

公开(公告)日：2017-09-12

申请号：US14342242

申请日：2012-08-28

申请人： Chunfang Lu ,  Youming Zhao ,  Cheng Jiang ,  Jijun Wang ,  Meng Wang ,  Yong Zhao ,  Weibin Liu ,  Ziqing Jiang ,  Ruilin You ,  Xianggang Du ,  Jia Fan

发明人： Chunfang Lu ,  Youming Zhao ,  Cheng Jiang ,  Jijun Wang ,  Meng Wang ,  Yong Zhao ,  Weibin Liu ,  Ziqing Jiang ,  Ruilin You ,  Xianggang Du ,  Jia Fan

IPC分类号： E01B1/00 ,  E01B3/40

CPC分类号： E01B1/007 ,  E01B1/002 ,  E01B1/004 ,  E01B3/40

摘要： A ballastless track system comprises a base; a track slab arranged above the base; a poured-field layer arranged between the base and the track slab, the poured-field layer being formed by filling self-compacting concrete, emulsified asphalt cement mortar or resin mortar, and the inside of the poured-field layer being of a steel bar structure; a connecting piece, the first end of the connecting piece extending into the track slab, and the second end of the connecting piece extending into the poured-field layer; and two rows of rail-seat arranged on the track slab in parallel; and rails arranged on the rail-seat. The ballastless track system is high in reliability, good in durability, and easy in construction and maintenance.

公开(公告)号：US20140203094A1

公开(公告)日：2014-07-24

申请号：US14342242

申请日：2012-08-28

申请人： Chunfang Lu ,  Youming Zhao ,  Cheng Jiang ,  Jijun Wang ,  Meng Wang ,  Yong Zhao ,  Weibin Liu ,  Ziqing Jiang ,  Ruilin You ,  Xianggang Du ,  Jia Fan

发明人： Chunfang Lu ,  Youming Zhao ,  Cheng Jiang ,  Jijun Wang ,  Meng Wang ,  Yong Zhao ,  Weibin Liu ,  Ziqing Jiang ,  Ruilin You ,  Xianggang Du ,  Jia Fan

IPC分类号： E01B1/00

CPC分类号： E01B1/007 ,  E01B1/002 ,  E01B1/004 ,  E01B3/40

摘要： A ballastless track system comprises a base; a track slab arranged above the base; a poured-field layer arranged between the base and the track slab, the poured-field layer being formed by filling self-compacting concrete, emulsified asphalt cement mortar or resin mortar, and the inside of the poured-field layer being of a steel bar structure; a connecting piece, the first end of the connecting piece extending into the track slab, and the second end of the connecting piece extending into the poured-field layer; and two rows of rail-seat arranged on the track slab in parallel; and rails arranged on the rail-seat. The ballastless track system is high in reliability, good in durability, and easy in construction and maintenance.

摘要翻译： 无碴轨道系统包括基座; 安装在基座上方的轨道板; 浇注场层布置在基部和轨道板之间，浇注层通过填充自密实混凝土，乳化沥青水泥砂浆或树脂砂浆形成，浇注层的内部由钢筋 结构体; 连接件的第一端延伸到轨道板中，并且连接件的第二端延伸到浇注层中; 和平行排列在轨道板上的两排轨座; 和轨道布置在轨座上。 无碴轨道系统的可靠性高，耐用性好，施工维护方便。

公开(公告)号：US20130264394A1

公开(公告)日：2013-10-10

申请号：US13994931

申请日：2011-12-15

申请人： Jijun Wang ,  Cheng Jiang ,  Weibin Liu ,  Yong Zhao ,  Meng Wang ,  Ziqing Jiang ,  Jia Fan ,  Xianggang Du

发明人： Jijun Wang ,  Cheng Jiang ,  Weibin Liu ,  Yong Zhao ,  Meng Wang ,  Ziqing Jiang ,  Jia Fan ,  Xianggang Du

IPC分类号： E01B1/00

CPC分类号： E01B1/002 ,  E01B3/40

摘要： Provided in the disclosure is a pre-stressed concrete track slab of slab-type ballast-less track, which includes a slab body (1), on which fastening embedded casings (4) are arranged. At least one row of longitudinal common steel bars (11) and at least one row of transverse common steel bars (12) are arranged in the slab body (1) along a length direction and a width direction. The longitudinal common steel bars (11) are insulated from the transverse common steel bars (12). At least one row of longitudinal pre-stressed steel bars (7) and at least one row of transverse pre-stressed steel bars (6) are fastened in the slab body (1) along the length direction and the width direction through anchor backing plates and fastener devices (8). In the pre-stress directions of the longitudinal pre-stressed steel bars (7) and the transverse pre-stressed steel bars (6), it is post-tensioned in both directions or it is pre-tensioned in one direction and post-tensioned in the other direction. Limiting structures (5) and grounding terminals (10) are also arranged on the slab body (1). The pre-stressed concrete track slab has the characteristics of light structural dead weight, small structure height, low manufacturing cost and deformation resistance.

摘要翻译： 本发明公开了一种板坯式无轨道预应力混凝土轨道板，包括板体（1），其上布置有紧固嵌入壳体（4）。 至少一排纵向普通钢筋（11）和至少一排横向普通钢筋（12）沿着长度方向和宽度方向布置在板坯体（1）中。 纵向普通钢筋（11）与横向普通钢筋（12）绝缘。 至少一排纵向预应力钢筋（7）和至少一排横向预应力钢筋（6）沿着长度方向和宽度方向通过锚固衬板（6）紧固在板体（1）中 和紧固件装置（8）。 在纵向预应力钢筋（7）和横向预应力钢筋（6）的预应力方向上，其沿两个方向被后张紧或者在一个方向上被预张紧并且被拉伸 在另一个方向。 限制结构（5）和接地端子（10）也布置在板体（1）上。 预应力混凝土轨道板具有结构自重轻，结构高度小，制造成本低，抗变形的特点。

公开(公告)号：US09196465B2

公开(公告)日：2015-11-24

申请号：US14123679

申请日：2012-06-01

申请人： Guangjun Nie ,  Tony Hu ,  Jia Fan ,  Yuliang Zhao ,  Mauro Ferrari

发明人： Guangjun Nie ,  Tony Hu ,  Jia Fan ,  Yuliang Zhao ,  Mauro Ferrari

IPC分类号： A61K38/00 ,  C07K2/00 ,  C07K4/00 ,  C07K5/00 ,  C07K7/00 ,  C07K14/00 ,  C07K17/00 ,  G01N1/00 ,  B01D59/44 ,  H01J49/00 ,  G01N33/68 ,  G01N33/74 ,  G01N1/38

CPC分类号： H01J49/0027 ,  G01N1/38 ,  G01N33/6848 ,  G01N33/74 ,  H01J49/00

摘要： A method for detecting hepcidin. Having a sample liquid in contact with a nanochip having a specific surface coating structure of silicon oxide, so that hepcidin is enriched with specificity; eluting the nanochip with an eluent; by performing mass spectrometric detection on the elution product, determining the hepcidin content in the elution product. The enrichment method substantially enhances the sensitivity and accuracy of mass spectrometric detection. A kit for detecting hepcidin comprising a sample diluent and a nanochip, the sample diluent comprising water, trifluoroacetic acid, and acetonitrile.

摘要翻译： 检测铁调素的方法。 使样品液体与具有氧化硅比表面涂层结构的纳米芯片接触，使得铁调素富集特异性; 用洗脱剂洗脱纳米芯片; 通过对洗脱产物进行质谱检测，测定洗脱产物中的铁调素含量。 浓缩法大大提高了质谱检测的灵敏度和准确性。 用于检测包含样品稀释剂和纳米芯片的铁调素的试剂盒，所述样品稀释剂包含水，三氟乙酸和乙腈。

公开(公告)号：US20140217277A1

公开(公告)日：2014-08-07

申请号：US14123679

申请日：2012-06-01

申请人： Guangjun Nie ,  Tony Hu ,  Jia Fan ,  Yuliang Zhao ,  Mauro Ferrari

发明人： Guangjun Nie ,  Tony Hu ,  Jia Fan ,  Yuliang Zhao ,  Mauro Ferrari

IPC分类号： H01J49/00 ,  G01N1/38

CPC分类号： H01J49/0027 ,  G01N1/38 ,  G01N33/6848 ,  G01N33/74 ,  H01J49/00

摘要： A method for detecting hepcidin. Having a sample liquid in contact with a nanochip having a specific surface coating structure of silicon oxide, so that hepcidin is enriched with specificity; eluting the nanochip with an eluent; by performing mass spectrometric detection on the elution product, determining the hepcidin content in the elution product. The enrichment method substantially enhances the sensitivity and accuracy of mass spectrometric detection. A kit for detecting hepcidin comprising a sample diluent and a nanochip, the sample diluent comprising water, trifluoroacetic acid, and acetonitrile.

摘要翻译： 检测铁调素的方法。 使样品液体与具有氧化硅的比表面涂层结构的纳米芯片接触，使得铁调素富集特异性; 用洗脱剂洗脱纳米芯片; 通过对洗脱产物进行质谱检测，测定洗脱产物中的铁调素含量。 浓缩法大大提高了质谱检测的灵敏度和准确性。 用于检测包含样品稀释剂和纳米芯片的铁调素的试剂盒，所述样品稀释剂包含水，三氟乙酸和乙腈。

公开(公告)号：US20130237456A1

公开(公告)日：2013-09-12

申请号：US13808129

申请日：2011-05-06

申请人： Jia Fan ,  JIan Zhou ,  Zhi Dai ,  Lei Yu ,  Jie Hu ,  Zheng Wang

发明人： Jia Fan ,  JIan Zhou ,  Zhi Dai ,  Lei Yu ,  Jie Hu ,  Zheng Wang

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/16 ,  C12Q2600/178

摘要： The present invention relates to a kit for diagnosing hepatocellular carcinoma consisting of plasma microRNA, a kit containing the same, and a new method therefor. The marker for diagnosing hepatocellular carcinoma consists of a plurality of nucleic acid molecules, each nucleic acid molecule encoding at least one microRNA sequence, preferably consists of nucleic acid molecules encoding hsa-miR-122, hsa-miR-192, hsa-miR-21, hsa-miR-223, hsa-miR-26a, hsa-miR-27a, hsa-miR-801 and hsa-miR-1228. The kit can be used for diagnosing hepatocellular carcinoma, especially early hepatocellular carcinoma, and also for discriminating plasma of at least one hepatocellular carcinoma patient from that of at east one healthy individual, at east one chronic hepatitis B patient, or at east one cirrhosis patient.

摘要翻译： 本发明涉及一种用于诊断由血浆微RNA组成的肝细胞癌的试剂盒，含有该微小RNA的试剂盒及其新方法。 用于诊断肝细胞癌的标记物由多个核酸分子组成，每个核酸分子编码至少一个microRNA序列，优选由编码hsa-miR-122，hsa-miR-192，hsa-miR-21的核酸分子组成 ，hsa-miR-223，hsa-miR-26a，hsa-miR-27a，hsa-miR-801和hsa-miR-1228。 该试剂盒可用于诊断肝细胞癌，特别是早期肝细胞癌，以及鉴别至少一例肝细胞癌患者的血浆与东部一个健康个体，东一个慢性乙型肝炎患者或东部一例肝硬化患者 。