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公开(公告)号:US20120234746A1
公开(公告)日:2012-09-20
申请号:US13496084
申请日:2010-09-14
申请人: John Howard , Edward F. Leonard , Thomas Qin
发明人: John Howard , Edward F. Leonard , Thomas Qin
IPC分类号: B01D63/06
CPC分类号: B01D63/02 , A61M1/1627 , A61M2206/16 , B01D65/00 , B01D2313/08 , B01D2313/21
摘要: A risk of thrombogenesis is minimized in a tubular fiber membrane filter by flowing blood or other fluid through a header manifold that ensures a minimum shear rate on the wetted surfaces without flow reversal, stagnation volumes, or a shear rate that is too high. In an embodiment, fluid is conveyed into a header space and into a manifold face at a perimeter of the header space. The header space has a progressively decreasing clearance that is minimal to provide for substantial shear rate and decreasing toward a minimum clearance in a region that is remote from the perimeter and vented by openings to the microtubular membrane fibers. Other features and embodiments are described.
摘要翻译: 在管状纤维膜过滤器中通过使血液或其它流体流过集管歧管来确保在润湿表面上的最小剪切速率而没有流动反转,停滞体积或过高的剪切速率,使血栓形成的风险最小化。 在一个实施例中,流体被传送到集管空间并进入集管面在集管空间的周边。 头部空间具有逐渐减小的间隙,其最小化以提供显着的剪切速率并且在远离周边的区域中朝向最小间隙减小并且通过开口排出到微管膜纤维。 描述其他特征和实施例。
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2.
公开(公告)号:US20120205306A1
公开(公告)日:2012-08-16
申请号:US13392519
申请日:2010-08-27
申请人: Ilan K. Reich , Edward F. Leonard , Michael Hill , John Howard
发明人: Ilan K. Reich , Edward F. Leonard , Michael Hill , John Howard
IPC分类号: B01D17/00
CPC分类号: B01D61/18 , A61M1/3472 , A61M2205/0244 , B01D63/081 , B01D2313/12
摘要: A microfluidic separation device suitable for high throughput applications such as medical treatments, and associated methods and systems, are described. Embodiments are suitable for treatment of end stage renal disease.
摘要翻译: 描述了适用于诸如医疗处理和相关方法和系统的高通量应用的微流体分离装置。 实施方案适用于治疗终末期肾病。
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3.
公开(公告)号:US20240235603A9
公开(公告)日:2024-07-11
申请号:US18386626
申请日:2023-11-03
申请人: John Howard
发明人: John Howard
IPC分类号: H04B1/58 , H04B1/04 , H04B7/0426
CPC分类号: H04B1/583 , H04B1/0458 , H04B7/043
摘要: A beam forming network system includes a first beam forming network having first and second ports, in which each of the first ports is operatively coupled to an antenna element; and a second beam forming network including third and fourth ports, in which each of the third ports is operatively coupled to one of the second ports using at least one of a phase shifter, attenuator, power divider, and/or hybrid coupler. A method of beam forming includes coupling each of the first ports associated with a first beam forming network operatively to one antenna element, and coupling each of the third ports associated with a second beam forming network operatively to one of the second ports associated with the first beam forming network using at least one of a phase shifter, attenuator, power divider, and/or hybrid coupler.
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公开(公告)号:US11855680B2
公开(公告)日:2023-12-26
申请号:US16891244
申请日:2020-06-03
申请人: John Howard
发明人: John Howard
IPC分类号: H01Q21/20 , H04B1/58 , H04B1/04 , H04B7/0426
CPC分类号: H04B1/583 , H04B1/0458 , H04B7/043
摘要: A beam forming network system includes a first beam forming network having first and second ports, in which each of the first ports is operatively coupled to an antenna element; and a second beam forming network including third and fourth ports, in which each of the third ports is operatively coupled to one of the second ports using at least one of a phase shifter, attenuator, power divider, and/or hybrid coupler. A method of beam forming includes coupling each of the first ports associated with a first beam forming network operatively to one antenna element, and coupling each of the third ports associated with a second beam forming network operatively to one of the second ports associated with the first beam forming network using at least one of a phase shifter, attenuator, power divider, and/or hybrid coupler.
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公开(公告)号:US10734733B2
公开(公告)日:2020-08-04
申请号:US14227634
申请日:2014-03-27
申请人: John Howard
发明人: John Howard , Chuck Wah Fung
摘要: An antenna array system provides simultaneous 360° coverage and includes Butler matrix beam forming networks connected to an antenna array, which includes narrow and/or broadband elements, and multiple transmitters, receivers, or transceivers to allow for 360° transmission and/or reception. The antenna array system can provide multiple beams, such as without limitation 8 or 16 beams, which can vary in beam crossing and/or overlap to provide simultaneous 360° coverage. An antenna array system includes a plurality of antenna elements configured in an array, a first Butler matrix operatively coupled to the plurality of antenna elements, and a second Butler matrix operatively coupled to the first Butler matrix. A method of providing simultaneous 360° coverage includes configuring a plurality of antenna elements in an array, coupling a first Butler matrix operatively to the plurality of antenna elements, and coupling a second Butler matrix operatively to the first Butler matrix.
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6.
公开(公告)号:US09905936B2
公开(公告)日:2018-02-27
申请号:US15388509
申请日:2016-12-22
申请人: John Howard
发明人: John Howard , Chuck Wah Fung
CPC分类号: H01Q21/06 , H01Q13/085 , H01Q21/0087 , H01Q21/064 , H01Q21/205 , H01Q21/30 , Y10T29/49016
摘要: An antenna array includes a plurality of antenna elements coupled in a common area and extending radially outward from the common area. At least one of the plurality of antenna elements includes a first antenna portion and a second antenna portion arranged in a configuration such that a gap is formed between the first antenna portion and the second antenna portion. The gap includes first spacing associated with a first operating frequency and a first operating wavelength, and a second spacing associated with a second operating frequency and a second operating wavelength. A proportion of the first spacing to the first wavelength is substantially equal to a proportion of the second spacing to the second wavelength, thereby providing a constant beamwidth over an operating frequency band. A method of arranging a plurality of antenna elements in an antenna array is also disclosed.
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公开(公告)号:US08841076B2
公开(公告)日:2014-09-23
申请号:US11388823
申请日:2006-03-24
申请人: Elizabeth A. Holmes , Ian Gibbons , Timothy M. Kemp , John Howard , Shaunak Roy
发明人: Elizabeth A. Holmes , Ian Gibbons , Timothy M. Kemp , John Howard , Shaunak Roy
CPC分类号: G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G06F19/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译: 本发明在医疗器械领域。 具体地说,本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号:US08558058B2
公开(公告)日:2013-10-15
申请号:US11219180
申请日:2005-09-02
申请人: Elizabeth Hood , John Howard
发明人: Elizabeth Hood , John Howard
CPC分类号: C12N15/8242 , C12N15/8246 , C12N15/8257
摘要: Expression of recombinant polysaccharide degrading enzymes in plants is described. In one embodiment, expression of the enzyme is preferentially directed to the seed of the plant. Expression may also be preferentially targeted to specific locations within the plant cell. Expression of cellulases in corn is shown. The result is the capacity to produce polysaccharide degrading enzymes in plants at commercially acceptable levels in a reliable manner. Methods of using same in production of ethanol is also described, including use of the plant-produced enzymes in the ethanol production process.
摘要翻译: 描述了重组多糖降解酶在植物中的表达。 在一个实施方案中,酶的表达优先针对植物的种子。 表达也可以优先靶向植物细胞内的特定位置。 显示玉米纤维素酶的表达。 结果是以可靠的方式以商业上可接受的水平在植物中产生多糖降解酶的能力。 还描述了在乙醇生产中使用其的方法,包括在乙醇生产过程中使用植物生产的酶。
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公开(公告)号:US20120052561A1
公开(公告)日:2012-03-01
申请号:US13286168
申请日:2011-10-31
申请人: Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
发明人: Elizabeth A. Holmes , Shaunak Roy , John Howard , Chengwang Wang , Ian Gibbons , Timothy M. Kemp , Shize Daniel Qi
CPC分类号: G01N21/76 , A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/150022 , A61B5/150099 , A61B5/150251 , A61B5/150763 , A61B5/150854 , A61B5/15142 , A61B5/157 , A61B5/412 , A61B5/417 , B01L3/50273 , B01L2300/021 , B01L2300/023 , B01L2300/044 , B01L2300/0636 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0877 , B01L2300/0883 , B01L2300/0887 , G01N33/50 , G01N33/53 , G01N33/5302 , G01N33/54386 , G01N2500/00 , G16H40/63 , Y02A90/26 , Y10T436/10 , Y10T436/11 , Y10T436/115831 , Y10T436/12 , Y10T436/143333
摘要: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
摘要翻译: 本发明在医疗器械领域。 具体地说,本发明提供允许从生物流体实时检测分析物的便携式医疗装置。 所述方法和装置对于为各种医疗应用提供点护理测试特别有用。
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公开(公告)号:US08115060B2
公开(公告)日:2012-02-14
申请号:US12390485
申请日:2009-02-22
申请人: John Howard , Erin Engelkrout
发明人: John Howard , Erin Engelkrout
CPC分类号: C12N15/8234 , C07K14/36 , C07K14/465 , C12N15/8267
摘要: A method of controlling germination of seed is provided in which a nucleic acid encoding a protein which causes inhibition of germination is transformed into a plant, operably linked with a promoter that expresses during germination. The protein is one in which a restoring substance can be applied to the seed and restores germination. Also provided is an amylase germination preferred promoter.
摘要翻译: 提供了一种控制种子发芽的方法,其中将编码引起抑制发芽的蛋白质的核酸转化到植物中,与在发芽过程中表达的启动子可操作地连接。 该蛋白质可以将恢复物质应用于种子并恢复萌发。 还提供了淀粉酶发芽优选的启动子。
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