AUTOMATIC REFINING APPARATUS, MULTI-WELL PLATE KIT AND METHOD FOR EXTRACTING HEXANE FROM BIOLOGICAL SAMPLES
    1.
    发明申请
    AUTOMATIC REFINING APPARATUS, MULTI-WELL PLATE KIT AND METHOD FOR EXTRACTING HEXANE FROM BIOLOGICAL SAMPLES 审中-公开
    自动精炼装置,多孔板包装和从生物样品中提取HEXAN的方法

    公开(公告)号:US20110009608A1

    公开(公告)日:2011-01-13

    申请号:US12920475

    申请日:2009-04-08

    IPC分类号: C07H21/00 B03C1/02 B03C1/30

    摘要: The present invention relates to an automatic refining apparatus for separating target materials from a plurality of biological sample solutions by using magnetic particles to which the magnetic particles are to be reversibly coupled, and to a multi-well plate kit for use in the automatic refining apparatus. Further, the present invention relates to a method for extracting nucleic acids from biological samples by using the above-described automatic refining apparatus. The present invention can be used in the automatic separation of nucleic acid, protein, and the like from biological samples.

    摘要翻译: 本发明涉及一种用于通过使用磁性颗粒可逆地耦合的磁性颗粒从多个生物样品溶液中分离目标材料的自动精炼装置,以及用于自动精炼装置的多孔板组件 。 此外,本发明涉及通过使用上述自动精制装置从生物样品中提取核酸的方法。 本发明可用于从生物样品中自动分离核酸,蛋白质等。

    Method for isolating a nucleic acid using particulate matter and a composition therefor
    3.
    发明授权
    Method for isolating a nucleic acid using particulate matter and a composition therefor 有权
    使用颗粒物分离核酸的方法及其组合物

    公开(公告)号:US08530639B2

    公开(公告)日:2013-09-10

    申请号:US12448134

    申请日:2007-12-11

    IPC分类号: C07H21/00

    CPC分类号: C07H21/00 C12N15/1003

    摘要: A method for isolating a nucleic acid from a biological sample includes applying particulate matter to promote co-aggregation and co-precipitation of insoluble aggregate by directly adding to the biological sample, adding to the biological sample in admixture with a cell lysis buffer, adding to the biological sample treated with a cell lysis buffer, adding to cell lysates in admixture with a buffer for forming denatured protein aggregate; or adding to cell lysates comprising the formed denatured protein aggregate. The particulate matter is selected from the group consisting of a material formed from an element of Ag, Fe, Ti, Al, Sn, Si, Cu, Mo, Ni, W or Zn, an oxide, a carbide, a nitride, a boride and a silicide thereof, and a mixture thereof, a polymer selected from PMMA (Poly Methyl MethAcrylate), polyethylene or polyurethane; and a mixture thereof. The insoluble aggregate comprises denatured protein aggregate and cell debris.

    摘要翻译: 从生物样品中分离核酸的方法包括通过直接添加到生物样品中来加入颗粒物质以促进不溶性聚集体的共聚和共沉淀,将生物样品与细胞裂解缓冲液混合,加入到 用细胞裂解缓冲液处理生物样品,加入细胞裂解物与缓冲液混合以形成变性蛋白质聚集体; 或加入包含形成的变性蛋白质聚集体的细胞裂解物。 颗粒物质选自由Ag,Fe,Ti,Al,Sn,Si,Cu,Mo,Ni,W或Zn的元素形成的材料,氧化物,碳化物,氮化物,硼化物 及其硅化物及其混合物,选自PMMA(聚甲基丙烯酸甲酯),聚乙烯或聚氨酯的聚合物; 及其混合物。 不溶性聚集体包含变性蛋白质聚集体和细胞碎片。

    METHOD FOR ISOLATING A NUCLEIC ACID USING PARTICULATE MATTER AND A COMPOSITION THEREFOR
    5.
    发明申请
    METHOD FOR ISOLATING A NUCLEIC ACID USING PARTICULATE MATTER AND A COMPOSITION THEREFOR 有权
    使用颗粒物分解核酸的方法及其组合物

    公开(公告)号:US20100197903A1

    公开(公告)日:2010-08-05

    申请号:US12448134

    申请日:2007-12-11

    IPC分类号: C07H21/00 B01J20/26 C09K3/00

    CPC分类号: C07H21/00 C12N15/1003

    摘要: Disclosed are a method for isolating a nucleic acid using particulate matter and a composition therefor. The method comprises essentially the steps of adding a lysis buffer and a neutralization buffer to a biological sample sequentially, and centrifuging cell lysates for at least 10 minutes to separate a solution comprising the nucleic acid and insoluble aggregate comprising denatured protein aggregate and cell debris. The particulate matter is added to and participates in co-aggregation and co-precipitation of denatured protein aggregate and cell debris, and co-aggregates and co-precipitates denatured protein aggregate and cell debris within a much shortened time, thereby to shorten the time and to increase the yield for the isolation of a nucleic acid, compared with conventional methods.

    摘要翻译: 公开了使用颗粒物质及其组合物分离核酸的方法。 该方法基本上包括以下步骤:依次向生物样品中加入裂解缓冲液和中和缓冲液,并离心细胞裂解物至少10分钟以分离包含核酸的溶液和包含变性蛋白质聚集体和细胞碎片的不溶性骨架。 添加颗粒物并参与变性蛋白质聚集体和细胞碎片的共聚和共沉淀,并在更短的时间内共同聚集和共沉淀变性蛋白质聚集体和细胞碎片,从而缩短时间和 以提高分离核酸的产量,与常规方法相比。

    Semiconductor device
    8.
    发明授权
    Semiconductor device 有权
    半导体器件

    公开(公告)号:US08208338B2

    公开(公告)日:2012-06-26

    申请号:US12719979

    申请日:2010-03-09

    申请人: Jong-Hoon Kim

    发明人: Jong-Hoon Kim

    IPC分类号: G11C5/14

    摘要: A semiconductor device is provided. The semiconductor device includes a chip having a plurality of first power voltage terminals connected in common to a first power voltage line, a plurality of second power voltage terminals connected in common with a second power voltage line, a first connection terminal, a second connection terminal connected to the first power voltage line or the second power voltage line, and an on-die capacitor. The semiconductor device also includes a package having a plurality of third power voltage terminals connected to the first power voltage terminals through a first wire by wire bonding during a packaging process and a plurality of fourth power voltage terminals connected to the second power voltage terminals through a second wire by wire bonding during the packaging process, and configured to package the chip, wherein one end of the on-die capacitor is connected to the first connection terminal, and the first connection terminal is connected to the second connection terminal through a third wire by wire bonding during the packaging process.

    摘要翻译: 提供半导体器件。 半导体器件包括具有与第一电源线共同连接的多个第一电源电压端子,与第二电源电压线共同连接的多个第二电力电压端子的第一连接端子,第二连接端子 连接到第一电源线或第二电源线,以及片上电容器。 该半导体器件还包括具有多个第三电源电压端子的封装,该多个第三电源电压端子通过在封装工艺期间的引线接合而通过第一电线连接到第一电源电压端子,以及多个第四电力电压端子,其通过一个 在封装过程中通过引线接合的第二线,并且被配置为封装所述芯片,其中所述片上电容器的一端连接到所述第一连接端子,并且所述第一连接端子通过第三线连接到所述第二连接端子 通过在包装过程中的引线键合。

    Sliding module for portable terminal
    9.
    发明授权
    Sliding module for portable terminal 有权
    便携式终端滑动模块

    公开(公告)号:US08036726B2

    公开(公告)日:2011-10-11

    申请号:US11411281

    申请日:2006-04-26

    IPC分类号: H04M1/00

    CPC分类号: H04M1/0237

    摘要: A sliding module for a portable terminal which has a first housing and a second housing sliding on the first housing is disclosed, the sliding module slidably coupling the first and second housings. The sliding module includes a sliding plate mounted on a surface of the first housing; at least one guide rod mounted on a surface of the second housing and slidably coupled to the sliding plate, the guide rod being extended in the longitudinal direction of the second housing; at least one first guide rib formed on the sliding plate; and at least one second guide rib formed on the surface of the second housing, wherein the second guide rib is slidably engaged with the first guide rib, and maintains at least partial engagement with the first guide rib within a sliding range of the second housing.

    摘要翻译: 公开了一种用于便携式终端的滑动模块,其具有在第一壳体上滑动的第一壳体和第二壳体,滑动模块可滑动地联接第一和第二壳体。 滑动模块包括安装在第一壳体的表面上的滑板; 至少一个安装在所述第二壳体的表面上并且可滑动地联接到所述滑板的引导杆,所述导杆沿所述第二壳体的纵向方向延伸; 形成在滑板上的至少一个第一引导肋; 以及形成在所述第二壳体的表面上的至少一个第二引导肋,其中所述第二引导肋与所述第一引导肋可滑动地接合,并且在所述第二壳体的滑动范围内保持与所述第一引导肋的至少部分接合。