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    Doppler flow imaging using optical coherence tomography
    5.
    发明授权
    Doppler flow imaging using optical coherence tomography 有权
    多普勒血流成像使用光学相干断层扫描

    公开(公告)号：US06735463B2

    公开(公告)日：2004-05-11

    申请号：US09468674

    申请日：1999-12-21

    申请人： Joseph A. Izatt ,  Manish D. Kulkarni ,  Siavash Yazdanfar ,  Andrew Rollins ,  Michael V. Sivak

    发明人： Joseph A. Izatt ,  Manish D. Kulkarni ,  Siavash Yazdanfar ,  Andrew Rollins ,  Michael V. Sivak

    IPC分类号： A61B502

    CPC分类号： A61B5/0073 ,  A61B5/0066 ,  A61B5/7257 ,  G01B9/02045 ,  G01B9/02069 ,  G01B9/02071 ,  G01B9/02072 ,  G01B9/02083 ,  G01B9/02091 ,  G01B2290/35 ,  G01B2290/60

    摘要： A method for generating a velocity-indicating, tomographic image of a sample in an optical coherence tomography system includes the steps of (a) acquiring cross-correlation data from the interferometer; (b) generating a grayscale image from the cross-correlation data indicative of a depth-dependent positions of scatterers in the sample; (c) processing the cross-correlation data to produce a velocity value and location of a moving scatterer in the sample; (d) assigning a color to the velocity value; and (f) merging the color into the grayscale image, at a point in the grayscale image indicative of the moving scatterer's location, to produce a velocity-indicating, tomographic image. Preferably a first color is assigned for a positive velocity value and a second color is assigned for a negative velocity value.

    摘要翻译： 一种用于在光学相干断层摄影系统中产生样本的速度指示断层图像的方法包括以下步骤：（a）从干涉仪获取互相关数据; （b）从指示样品中散射体的深度相关位置的互相关数据中生成灰度图像; （c）处理互相关数据以产生样品中运动散射体的速度值和位置; （d）为速度值分配颜色; 以及（f）在指示运动散射体位置的灰度图像中将颜色合并成灰度图像，以产生速度指示的断层图像。 优选地，将第一颜色分配给正速度值，并且将第二颜色分配给负速度值。

    METHODS AND SYSTEMS OF OPTICAL IMAGING FOR TARGET DETECTION IN A SCATTERING MEDIUM
    7.
    发明申请
    METHODS AND SYSTEMS OF OPTICAL IMAGING FOR TARGET DETECTION IN A SCATTERING MEDIUM 有权
    光学成像技术在散射介质中的目标检测方法与系统

    公开(公告)号：US20120128264A1

    公开(公告)日：2012-05-24

    申请号：US12952359

    申请日：2010-11-23

    申请人： Siavash Yazdanfar ,  Floribertus Heukensfeldt Jansen ,  Stephen Lomnes ,  Xinghua Wang

    发明人： Siavash Yazdanfar ,  Floribertus Heukensfeldt Jansen ,  Stephen Lomnes ,  Xinghua Wang

    IPC分类号： G06K9/40 ,  G01J1/58

    CPC分类号： A61B5/0059 ,  A61B5/0064

    摘要： A method for enhancing contrast in fluorescence imaging is provided. The method comprises providing a patterned illumination source for illuminating one or more regions corresponding to a scan step, scanning at least a portion of a surface of a subject using a plurality of scan steps, acquiring image frames corresponding to two or more scan steps, deducting a background fluorescence from the image frames corresponding to the two or more scan steps to form one or more processed image frames, and reconstructing an image using one or more of the processed image frames.

    摘要翻译： 提供了一种增强荧光成像对比度的方法。 该方法包括提供用于照亮与扫描步骤相对应的一个或多个区域的图案化照明源，使用多个扫描步骤扫描对象的表面的至少一部分，获取对应于两个或更多个扫描步骤的图像帧，扣除 来自对应于两个或更多个扫描步骤的图像帧的背景荧光，以形成一个或多个经处理的图像帧，以及使用一个或多个处理后的图像帧重建图像。

    OBJECTIVE FOR OPTICAL IMAGING SYSTEMS
    8.
    发明申请
    OBJECTIVE FOR OPTICAL IMAGING SYSTEMS 有权
    光学成像系统的目标

    公开(公告)号：US20110043916A1

    公开(公告)日：2011-02-24

    申请号：US12543785

    申请日：2009-08-19

    申请人： Xinghua Wang ,  Mark Marshall Meyers ,  Siavash Yazdanfar

    发明人： Xinghua Wang ,  Mark Marshall Meyers ,  Siavash Yazdanfar

    IPC分类号： G02B23/24 ,  G02B27/42

    CPC分类号： G02B23/243

    摘要： A wide angle hybrid refractive-diffractive endoscope objective is provided. The objective comprises a negative meniscus lens having a first surface and a second surface; a stop adjacent to the negative meniscus lens; a positive lens adjacent to the negative lens and having a first surface and a second surface; and a hybrid refractive-diffractive element adjacent to the positive lens and having a first surface and a second surface, wherein one of the first surface, or the second surface comprises a diffractive surface, wherein the objective has an effective focal length in a range from about 0.8 mm to about 1.6 mm.

    摘要翻译： 提供广角混合折射衍射内窥镜目的。 该目的包括具有第一表面和第二表面的负凹凸透镜; 靠近负弯月透镜的止动件; 与透镜相邻并具有第一表面和第二表面的正透镜; 以及与所述正透镜相邻并且具有第一表面和第二表面的混合折射衍射元件，其中所述第一表面或所述第二表面中的一个包括衍射表面，其中所述物镜具有在以下范围内的有效焦距： 约0.8mm至约1.6mm。

    Iris imaging system and method for the same
    9.
    发明授权
    Iris imaging system and method for the same 有权
    虹膜成像系统和方法相同

    公开(公告)号：US07824034B2

    公开(公告)日：2010-11-02

    申请号：US11857581

    申请日：2007-09-19

    申请人： Frederick Wilson Wheeler ,  Siavash Yazdanfar

    发明人： Frederick Wilson Wheeler ,  Siavash Yazdanfar

    IPC分类号： A61B3/14 ,  A61B3/00 ,  A61B3/10

    CPC分类号： A61B3/1216 ,  A61B3/14

    摘要： An iris imaging system is provided. The iris imaging system includes at least one light source configured to illuminate an iris at a spectrum of light. The iris imaging system also includes at least one image capturing device including at least one of an indium-gallium-arsenide, lead sulphide, and lead selenide based detector and configured to capture an image of the iris via light reflected from the iris at the spectrum. The device is further configured to provide a signal representing one or more features of the iris in response to the light reflected from the iris.

    摘要翻译： 提供虹膜成像系统。 虹膜成像系统包括至少一个被配置为以光谱照射虹膜的光源。 虹膜成像系统还包括至少一个图像捕获装置，其包括砷化铟镓，硫化铅和基于硒化铅的检测器中的至少一种，并被配置为通过光谱从光谱反射的光线捕获虹膜的图像 。 该装置还被配置为响应于从虹膜反射的光来提供表示虹膜的一个或多个特征的信号。

    Endoscope objective lens with large entrance pupil diameter and high numerical aperture
    10.
    发明授权
    Endoscope objective lens with large entrance pupil diameter and high numerical aperture 有权
    具有大入口光瞳直径和高数值孔径的内窥镜物镜

    公开(公告)号：US07821720B2

    公开(公告)日：2010-10-26

    申请号：US12125512

    申请日：2008-05-22

    申请人： Xinghua Wang ,  Siavash Yazdanfar

    发明人： Xinghua Wang ,  Siavash Yazdanfar

    IPC分类号： G02B21/02 ,  A61B1/00

    CPC分类号： G02B23/243

    摘要： An endoscope objective lens for collecting combined bright field (white light) and fluorescence images includes a negative lens group, a stop, and a positive lens group. The lens has a combination of large entrance pupil diameter (≧0.4 mm) for efficiently collecting weak fluorescence light, large ratio between the entrance pupil diameter and the maximum outside diameter (Dentrance/Dmax larger than 0.2), large field of view (FFOV≧120°) and favorably corrected spherical, lateral chromatic and Petzval field curvature for both visible and near infrared wavelengths.

    摘要翻译： 用于收集组合亮场（白光）和荧光图像的内窥镜物镜包括负透镜组，光阑和正透镜组。 透镜具有大的入射光瞳直径（≥0.4mm）的组合，用于有效地收集弱荧光，入射光瞳直径和最大外径之间的大比（Dentrance / Dmax大于0.2），大视场（FFOV≥ 120°），并且对于可见光和近红外波长都有良好校正的球面，横向色度和Petzval场曲率。