Method and system for quantitative image correction for optical coherence tomography
    4.
    发明授权
    Method and system for quantitative image correction for optical coherence tomography 有权
    光学相干断层扫描定量图像校正方法与系统

    公开(公告)号:US07072047B2

    公开(公告)日:2006-07-04

    申请号:US10619574

    申请日:2003-07-14

    IPC分类号: G01B9/02

    摘要: A method of correcting optical coherence tomography (OCT) image data obtained from a layered media sample includes identifying at least one interface from the obtained OCT data and correcting the OCT data for distortion at the at least one interface. The OCT image data can be corrected for extrinsic distortions, such as those caused by scan geometry, as well as, intrinsic distortions, such as those caused by refraction at each interface.

    摘要翻译: 校正从分层介质样本获得的光学相干断层摄影(OCT)图像数据的方法包括从所获得的OCT数据识别至少一个接口,并且在所述至少一个界面处校正OCT数据以进行失真。 OCT图像数据可以被校正为外部失真,例如由扫描几何引起的失真,以及固有失真,例如由每个界面处的折射造成的。

    Interferometers for optical coherence domain reflectometry
    5.
    发明授权
    Interferometers for optical coherence domain reflectometry 有权
    用于光学相干畴反射测量的干涉仪

    公开(公告)号:US07362444B2

    公开(公告)日:2008-04-22

    申请号:US11470079

    申请日:2006-09-05

    IPC分类号: G01B11/02 G01B9/02

    摘要: An interferometer system includes an optical radiation source, an optical circulator connected between the optical radiation source and a sample location for transmitting optical radiation from the optical radiation source to the sample location, an output of the optical circulator connected to direct optical radiation to an optical detector. Various embodiments of such a system are possible. A method of performing OCDR or OCT imaging of a sample which involves the steps of: (a) producing low coherence optical radiation; (b) directing at least some of the low coherence optical radiation through an optical circulator to the sample; (c) reflecting at least some of the low coherence optical radiation off of the sample; and (d) detecting at least some of the reflected low coherence optical radiation and producing an electrical signal corresponding thereto.

    摘要翻译: 干涉仪系统包括光辐射源,连接在光辐射源和用于将光辐射从光辐射源传送到采样位置的采样位置之间的光循环器,连接到直接光辐射的光循环器的输出到光学 探测器。 这种系统的各种实施例是可能的。 执行样本的OCDR或OCT成像的方法,其包括以下步骤:(a)产生低相干光辐射; (b)将至少一些低相干光辐射通过光循环器引导到样品; (c)反射离开样品的至少一些低相干光辐射; 和(d)检测至少一些反射的低相干光辐射并产生与其对应的电信号。

    Frequency-encoded parallel OCT and associated systems and methods
    6.
    发明授权
    Frequency-encoded parallel OCT and associated systems and methods 有权
    频率编码的并行OCT和相关系统和方法

    公开(公告)号:US06775007B2

    公开(公告)日:2004-08-10

    申请号:US10059723

    申请日:2002-01-29

    IPC分类号: G01B902

    摘要: Rapid scan optical delay techniques are used in parallel implementation of OCT using a detector and signal processing can be carried out using algorithms. Frequency encoded parallel OCT and multi-path, frequency encoded reference delay networks are used. A large number of frequency-correlated depth channels are used to acquire multiple depth scans of a sample. A different frequency shift (Doppler shift) on each different path length, or delay, is used to obtain simultaneous respective signals and, thus, information about the sample, from different depths in the sample. Reference delay line functions are obtained using bulk optics, integrated optics and fiber optics.

    摘要翻译: 快速扫描光延迟技术用于使用检测器并行执行OCT,并且可以使用算法执行信号处理。 使用频率编码的并行OCT和多路径,频率编码的参考延迟网络。 使用大量频率相关深度通道来采集样本的多个深度扫描。 使用每个不同路径长度或延迟上的不同频移(多普勒频移)来从样本中的不同深度获得相应的信号,从而获得关于样本的信息。 参考延迟线功能使用体光学,集成光学和光纤获得。

    Method and apparatus for polarization-sensitive optical coherence tomography
    7.
    发明授权
    Method and apparatus for polarization-sensitive optical coherence tomography 有权
    用于偏振敏感光学相干断层扫描的方法和装置

    公开(公告)号:US07826059B2

    公开(公告)日:2010-11-02

    申请号:US10055282

    申请日:2002-01-22

    IPC分类号: G01B9/02

    摘要: A method and apparatus for extracting the vector optical properties of biological samples with micron-scale resolution in three dimensions, using polarization-sensitive optical coherence tomography (PS-OCT). The method measures net retardance, net fast axis, and reflectivity. Polarization sensing is accomplished by illuminating the sample with at least three separate polarization states, using consecutive acquisitions of the same pixel, A-scan, or B-scan. The method can be implemented using non-polarization-maintaining fiber and a single detector. This PS-OCT method reported measures fast axis explicitly. In a calibration test of the system, net retardance was measured with an average error of 7.5° (standard deviation 2.2°) over the retardance range 0° to 180°, and fast axis with average error of 4.8° over the range 0° to 180°.

    摘要翻译: 一种使用偏振光敏光学相干断层扫描(PS-OCT)三维提取微尺度分辨率的生物样品的矢量光学性质的方法和装置。 该方法测量净延迟,净快轴和反射率。 通过使用相同像素,A扫描或B扫描的连续采集,以至少三个单独的极化状态照射样本来实现极化感测。 该方法可以使用非偏振维持光纤和单个检测器来实现。 这种PS-OCT方法报道了快轴测量。 在系统的校准测试中,在0°至180°的延迟范围内测量平均误差为7.5°(标准偏差2.2°)的净延迟,平均误差为4.8°的快轴在0°至 180°。

    Interferometers for optical coherence tomography and reflectometry
    8.
    发明授权
    Interferometers for optical coherence tomography and reflectometry 有权
    用于光学相干断层扫描和反射测量的干涉仪

    公开(公告)号:US07102756B2

    公开(公告)日:2006-09-05

    申请号:US10646202

    申请日:2003-08-22

    IPC分类号: G01B9/02

    摘要: An interferometer system includes an optical radiation source, an optical circulator connected between the optical radiation source and a sample location for transmitting optical radiation from the optical radiation source to the sample location, an output of the optical circulator connected to direct optical radiation to an optical detector. Various embodiments of such a system are possible. A method of performing OCDR or OCT imaging of a sample which involves the steps of: (a) producing low coherence optical radiation; (b) directing at least some of the low coherence optical radiation through an optical circulator to the sample; (c) reflecting at least some of the low coherence optical radiation off of the sample; and (d) detecting at least some of the reflected low coherence optical radiation and producing an electrical signal corresponding thereto.

    摘要翻译: 干涉仪系统包括光辐射源,连接在光辐射源和用于将光辐射从光辐射源传送到采样位置的采样位置之间的光循环器,连接到直接光辐射的光循环器的输出到光学 探测器。 这种系统的各种实施例是可能的。 执行样本的OCDR或OCT成像的方法,其包括以下步骤:(a)产生低相干光辐射; (b)将至少一些低相干光辐射通过光循环器引导到样品; (c)反射离开样品的至少一些低相干光辐射; 和(d)检测至少一些反射的低相干光辐射并产生与其对应的电信号。

    Interferometers for optical coherence domain reflectometry and optical coherence tomography using nonreciprocal optical elements
    9.
    发明授权
    Interferometers for optical coherence domain reflectometry and optical coherence tomography using nonreciprocal optical elements 有权
    用于光学相干畴反射测量和使用非互易光学元件的光学相干断层扫描的干涉仪

    公开(公告)号:US06657727B1

    公开(公告)日:2003-12-02

    申请号:US09393761

    申请日:1999-09-10

    IPC分类号: G01B902

    摘要: An interferometer system includes an optical radiation source, an optical circulator connected between the optical radiation source and a sample location for transmitting optical radiation from the optical radiation source to the sample location, an output of the optical circulator connected to direct optical radiation to an optical detector. Various embodiments of such a system are possible. A method of performing OCDR or OCT imaging of a sample which involves the steps of: (a) producing low coherence optical radiation; (b) directing at least some of the low coherence optical radiation through an optical circulator to the sample; (c) reflecting at least some of the low coherence optical radiation off of the sample; and (d) detecting at least some of the reflected low coherence optical radiation and producing an electrical signal corresponding thereto.

    摘要翻译: 干涉仪系统包括光辐射源,连接在光辐射源和用于将光辐射从光辐射源传送到采样位置的采样位置之间的光循环器,连接到直接光辐射的光循环器的输出到光学 探测器。 这种系统的各种实施例是可能的。 执行样本的OCDR或OCT成像的方法,其包括以下步骤:(a)产生低相干光辐射; (b)将至少一些低相干光辐射通过光循环器引导到样品; (c)反射离开样品的至少一些低相干光辐射; 和(d)检测至少一些反射的低相干光辐射并产生与其对应的电信号。