Synthesis of decitabine
    1.
    发明授权
    Synthesis of decitabine 有权
    地西他滨的合成

    公开(公告)号:US08586729B2

    公开(公告)日:2013-11-19

    申请号:US12572578

    申请日:2009-10-02

    IPC分类号: C08B37/00 C07H5/04 C07H5/06

    CPC分类号: C07H13/08 C07H19/12

    摘要: A method for producing a β-enriched protected decitabine comprising: a) coupling a protected 2-deoxy-ribofuranose with a protected 5-azacytosine in the presence of a catalyst to form a reaction mixture comprising the protected decitabine of formula I; and b) quenching the reaction mixture of step a) with a base. The β-enriched protected decitabine so made may be deprotected to produce a decitabine product in a high yield and purity.

    摘要翻译: 一种制备富含β-的受保护的地西他滨的方法,包括:a)在催化剂存在下将受保护的2-脱氧 - 呋喃核糖与受保护的5-氮杂胞嘧啶偶联,形成包含式I的受保护的地西他滨的反应混合物; 和b)将碱的步骤a)的反应混合物淬灭。 如此制备的β-富集的保护的地西他滨可以去保护以产生高产率和纯度的地西他滨产品。

    Synthesis of Decitabine
    2.
    发明申请
    Synthesis of Decitabine 有权
    地西他滨的合成

    公开(公告)号:US20100087637A1

    公开(公告)日:2010-04-08

    申请号:US12572578

    申请日:2009-10-02

    IPC分类号: C07H19/12

    CPC分类号: C07H13/08 C07H19/12

    摘要: A method for producing a β-enriched protected decitabine comprising: a) coupling a protected 2-deoxy-ribofuranose with a protected 5-azacytosine in the presence of a catalyst to form a reaction mixture comprising the protected decitabine of formula I; and b) quenching the reaction mixture of step a) with a base. The β-enriched protected decitabine so made may be deprotected to produce a decitabine product in a high yield and purity.

    摘要翻译: 一种生产富集的受保护的地西他滨的方法,包括:a)在催化剂存在下将受保护的2-脱氧 - 呋喃核糖与受保护的5-氮杂胞嘧啶偶联,形成包含式I的受保护的地西他滨的反应混合物; 和b)将碱的步骤a)的反应混合物淬灭。 如此制备的富含生物保护的地西他滨可以去保护以产生高产率和纯度的地西他滨产品。

    Eye motion sensing method, flexible contact body, external sensing coil and system
    3.
    发明申请
    Eye motion sensing method, flexible contact body, external sensing coil and system 审中-公开
    眼动检测方法,柔性接触体,外部感应线圈及系统

    公开(公告)号:US20160278634A1

    公开(公告)日:2016-09-29

    申请号:US15095222

    申请日:2016-04-11

    申请人: Kun Hu

    发明人: Kun Hu

    摘要: The present invention discloses an eye motion sensing method, a flexible contact body, an external sensing coil, and a system. The method may include: sensing an eye motion by using a servo motion signal of a permanent magnet implanted into a flexible contact body; applying at least four coils disposed externally on a same plane, and monitoring a servo motion of the permanent magnet according to an electromotive force in the coils; and converting the electromotive force to restore an eye motion signal. The present invention can use the sensing coils distributed around an eyepit to detect the electromotive force generated when the eye motion leads to the servo motion of the flexible contact body, and analyze the electromotive force. Accordingly, the eye motion triggered by a perceptual task can be analyzed objectively.

    摘要翻译: 本发明公开了一种眼动检测方法,柔性接触体,外部检测线圈和系统。 该方法可以包括:通过使用注入到柔性接触体中的永久磁体的伺服运动信号来感测眼睛运动; 将至少四个线圈设置在同一平面上的外部,并根据所述线圈中的电动势监测所述永磁体的伺服运动; 并转换电动势以恢复眼动信号。 本发明可以使用分布在眼罩周围的感测线圈来检测当眼睛运动导致柔性接触体的伺服运动时产生的电动势,并分析电动势。 因此,可以客观地分析由感知任务触发的眼动。

    HUMAN BODY TUMBLING DETECTION METHOD AND DEVICE AND MOBILE TERMINAL SYSTEM
    4.
    发明申请
    HUMAN BODY TUMBLING DETECTION METHOD AND DEVICE AND MOBILE TERMINAL SYSTEM 有权
    人体身体检测方法与装置及移动终端系统

    公开(公告)号:US20160210835A1

    公开(公告)日:2016-07-21

    申请号:US15084508

    申请日:2016-03-30

    申请人: Kun Hu

    发明人: Kun Hu

    IPC分类号: G08B21/04

    CPC分类号: G08B21/043 A61B5/1117

    摘要: A human body tumbling detection method and device and a mobile terminal system are disclosed. The method may include: when detecting that resultant acceleration of a human body is less than a low acceleration threshold a0, capturing a resultant acceleration sequence I0 within fixed time; in a two-dimensional coordinate system using resultant acceleration and time as coordinate axes and a0 as a reference line, calculating a curve area above the reference line and a curve area below the reference line that are enclosed by curves in I0 coordinates and the reference line; and when a difference between the curve area above the reference line and the curve area below the reference line is less than a curve area threshold ΔS, and time occupied by resultant acceleration below the reference line is greater than a low acceleration time threshold ΔT, determining that the human body tumbles.

    摘要翻译: 公开了一种人体翻滚检测方法和装置以及移动终端系统。 该方法可以包括:当检测到人体的合成加速度小于低加速度阈值a0时,在固定时间内捕获合成加速度序列I0; 在使用合成加速度和时间作为坐标轴的二维坐标系中,将a0作为参考线,计算参考线上方的曲线区域和参考线下方的曲线区域,该曲线区域由I0坐标和参考线 ; 并且当参考线上方的曲线区域与参考线下方的曲线区域之间的差小于曲线区域阈值&Dgr; S,并且由参考线以下的合成加速占据的时间大于低加速度时间阈值&Dgr ; T,确定人体翻滚。

    METHOD AND SYSTEM FOR BUILDING A HUMAN FALL DETECTION MODEL
    5.
    发明申请
    METHOD AND SYSTEM FOR BUILDING A HUMAN FALL DETECTION MODEL 审中-公开
    一种建立人体角度检测模型的方法和系统

    公开(公告)号:US20160210562A1

    公开(公告)日:2016-07-21

    申请号:US15084512

    申请日:2016-03-30

    申请人: Kun Hu

    发明人: Kun Hu

    摘要: The present invention discloses a method and a system for building a human fall detection model. The method can include: collecting the speed information of one and more human fall samples in the human fall process; the speed information includes resultant acceleration, speed and time; analyzing the characteristics of the speed information, calculating and extracting low acceleration threshold value a0, resultant acceleration series within fixed time I0, high acceleration threshold value a1, curve area threshold value ΔS and low acceleration time threshold value ΔT, and building the fall detection mechanism. The system of the present invention fully takes into account the characteristics of human body's movement behaviors, so as to increase the detection rate and reduce the misjudgment rate.

    摘要翻译: 本发明公开了一种建立人类跌倒检测模型的方法和系统。 该方法可以包括:在人类跌倒过程中收集一个或多个人类秋天样本的速度信息; 速度信息包括合成加速度,速度和时间; 分析速度信息的特点,计算和提取低加速度阈值a0,固定时间内I0,高加速度阈值a1,曲线面积阈值和Dgr; S和低加速度时间阈值Dgr; T和建筑物 跌倒检测机制。 本发明的系统充分考虑了人体运动行为的特点,提高了检测率,降低了误判率。

    METHOD AND APPARATUS FOR PRECISELY PERCEIVING INDOOR ACTIVITY
    6.
    发明申请
    METHOD AND APPARATUS FOR PRECISELY PERCEIVING INDOOR ACTIVITY 审中-公开
    方法和设备精确的室内活动

    公开(公告)号:US20160278668A1

    公开(公告)日:2016-09-29

    申请号:US15095219

    申请日:2016-04-11

    申请人: Kun Hu

    发明人: Kun Hu

    IPC分类号: A61B5/11 G01V1/00 A61B5/00

    摘要: The present invention discloses a method and an apparatus for precisely perceiving an indoor activity. The method may include: receiving a vibration signal on a floor by using multiple vibration sensors disposed according to a preset rule; and determining a location of a vibration source according to a phase difference of a vibration signal of the same vibration source in different vibration sensors. The monitoring performed on the indoor activity in the present invention can be performed without disturbing the monitored person, and can resolve the concern about leakage of privacy of the monitored person.

    摘要翻译: 本发明公开了一种精确地感知室内活动的方法和装置。 该方法可以包括:通过使用根据预设规则布置的多个振动传感器在地板上接收振动信号; 以及根据不同振动传感器中相同振动源的振动信号的相位差确定振动源的位置。 在本发明中对室内活动进行的监视可以在不干扰受监视的人的情况下进行,并且可以解决对被监视人的隐私泄露的担心。

    Eye motion sensing method, flexible contact body, external sensing coil and system

    公开(公告)号:US10111587B2

    公开(公告)日:2018-10-30

    申请号:US15095222

    申请日:2016-04-11

    申请人: Kun Hu

    发明人: Kun Hu

    摘要: The present invention discloses an eye motion sensing method, a flexible contact body, an external sensing coil, and a system. The method may include: sensing an eye motion by using a servo motion signal of a permanent magnet implanted into a flexible contact body; applying at least four coils disposed externally on a same plane, and monitoring a servo motion of the permanent magnet according to an electromotive force in the coils; and converting the electromotive force to restore an eye motion signal. The present invention can use the sensing coils distributed around an eyepit to detect the electromotive force generated when the eye motion leads to the servo motion of the flexible contact body, and analyze the electromotive force. Accordingly, the eye motion triggered by a perceptual task can be analyzed objectively.

    Digital portable pulse oximeter and battery-powered control method thereof
    8.
    发明授权
    Digital portable pulse oximeter and battery-powered control method thereof 有权
    数字便携式脉搏血氧计及其电池供电控制方法

    公开(公告)号:US09402572B2

    公开(公告)日:2016-08-02

    申请号:US13991617

    申请日:2012-03-09

    IPC分类号: A61B5/1455 A61B5/00

    摘要: The present invention relates to a digital portable pulse oximeter and battery-powered control method thereof. The automatic switching of the power supply is achieved by adding a Hall circuit, and the data displayed is allowed to always face the users by adding an acceleration sensor to the circuit. The advantageous effects of the present invention compared with the prior art are: Users can always read the data from the front side no matter which way they move. The digital portable pulse oximeter of the present invention can be automatically turned on just by inserting a finger, without having to press the switch button, and cut off the power supply by pulling out the finger, as well as judge intelligently whether to continue the measurement after the finger has been pulled out. If yes, the power supply will stay on, which reduces the energy waste and low efficiency caused by the restarting program initialization, improves the use efficiency of the battery and prolongs the battery life.

    摘要翻译: 本发明涉及一种数字便携式脉搏血氧计及其电池供电控制方法。 通过添加霍尔电路来实现电源的自动切换,并且通过向电路添加加速度传感器,允许所显示的数据总是面对用户。 与现有技术相比,本发明的有益效果是:无论使用哪种方式,用户都可以从前端读取数据。 本发明的数字式便携式脉搏血氧饱和度仪可以通过插入手指而自动开启,而无需按下开关按钮,并通过拔出手指来切断电源,并且智能地判断是否继续测量 手指拔出后。 如果是,电源将保持开启,从而减少重启程序初始化造成的能源浪费和低效率,提高电池的使用效率,延长电池寿命。

    Teeth cleaning device
    10.
    发明授权
    Teeth cleaning device 有权
    牙齿清洁装置

    公开(公告)号:US08967163B2

    公开(公告)日:2015-03-03

    申请号:US13895530

    申请日:2013-05-16

    申请人: Kun Hu

    发明人: Kun Hu

    摘要: A teeth cleaning device with a core pump area that provides positive pressure to push out water jetting streams and negative pressure to retract the floss attached to a piston, while the power input has enhanced torque due to the bevel gear structure; an optional spring may be placed inside the piston assembly to add to the reciprocating power, and thus creating more effective water jetting and floss oscillating motions for better teeth cleaning.

    摘要翻译: 具有芯泵区域的牙齿清洁装置,其提供正压力以推出水喷射流和负压以缩回附接到活塞的牙线,同时电力输入由于锥齿轮结构而具有增强的扭矩; 可选的弹簧可以放置在活塞组件内部以增加往复动力,从而产生更有效的喷水和牙线摆动运动,以更好地清洁牙齿。