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    Cell based signal generation
    1.
    发明授权
    Cell based signal generation 失效

    公开(公告)号：US07022513B2

    公开(公告)日：2006-04-04

    申请号：US10200013

    申请日：2002-07-18

    申请人： Jun Xu ,  Joshua Trueheart

    发明人： Jun Xu ,  Joshua Trueheart

    IPC分类号： C12N1/16

    CPC分类号： C07K14/39 ,  C07K2319/00

    摘要： The present invention makes available a rapid, reproducible, robust assay system for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular protein, e.g., a receptor or ion channel. The subject assay enables rapid screening of large numbers of compounds to identify those which act as an agonist or antagonist to the bioactivity of the cellular protein. In particular, the assay of the invention makes use of a cell that harbors a protein that is responsive to a cellular signal transduction pathway. The protein is operatively linked to a polypeptide which causes a detectable signal to be generated upon stimulation of the pathway, e.g., when a compound interacts with and modulates the activity of a cellular receptor or ion channel of the cell. Thus, the cell provides a signal generation means comprising a novel fusion protein the expression of which is independent of stimulation/activation of the signal transduction pathway, but the activity of which is responsive to the signal transduction pathway.

    Cell based signal generation
    2.
    发明授权
    Cell based signal generation 失效
    基于单元的信号生成

    公开(公告)号：US06504008B1

    公开(公告)日：2003-01-07

    申请号：US09241888

    申请日：1999-02-01

    申请人： Jun Xu ,  Joshua Trueheart

    发明人： Jun Xu ,  Joshua Trueheart

    IPC分类号： C07K1400

    CPC分类号： C07K14/39 ,  C07K2319/00

    摘要： The present invention makes available a rapid, reproducible, robust assay system for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular protein, e.g., a receptor or ion channel. The subject assay enables rapid screening of large numbers of compounds to identify those which act as an agonist or antagonist to the bioactivity of the cellular protein. In particular, the assay of the invention makes use of a cell that harbors a protein that is responsive to a cellular signal transduction pathway. The protein is operatively linked to a polypeptide which causes a detectable signal to be generated upon stimulation of the pathway, e.g., when a compound interacts with and modulates the activity of a cellular receptor or ion channel of the cell. Thus, the cell provides a signal generation means comprising a novel fusion protein the expression of which is independent of stimulation/activation of the signal transduction pathway, but the activity of which is responsive to the signal transduction pathway.

    摘要翻译： 本发明提供了用于筛选和鉴定与细胞蛋白例如受体或离子通道特异性相互作用并调节细胞蛋白质的活性的药学有效化合物的快速，可重复，稳定的测定系统。 本发明分析使得能够快速筛选大量的化合物以鉴定那些充当细胞蛋白的生物活性的激动剂或拮抗剂的化合物。 特别地，本发明的测定方法利用了含有对细胞信号转导途径有响应的蛋白质的细胞。 蛋白质可操作地连接到多肽，其在刺激途径时引起可检测信号的产生，例如当化合物与细胞的细胞受体或离子通道的活性相互作用并调节其活性时。 因此，细胞提供了包含新型融合蛋白的信号产生装置，其表达与信号转导途径的刺激/激活无关，但其活性对信号转导途径有反应。

    Neck pillow
    3.
    外观设计
    Neck pillow 有权

    公开(公告)号：USD872502S1

    公开(公告)日：2020-01-14

    申请号：US29656671

    申请日：2018-07-16

    申请人： Jun Xu

    设计人： Jun Xu

    Method and terminal for feeding back channel state information
    6.
    发明授权
    Method and terminal for feeding back channel state information 有权
    用于反馈信道状态信息的方法和终端

    公开(公告)号：US09258048B2

    公开(公告)日：2016-02-09

    申请号：US13695431

    申请日：2011-03-10

    申请人： Ruyue Li ,  Jun Xu ,  Yijian Chen ,  Bo Dai ,  Junfeng Zhang

    发明人： Ruyue Li ,  Jun Xu ,  Yijian Chen ,  Bo Dai ,  Junfeng Zhang

    IPC分类号： H04L12/26 ,  H04B7/06 ,  H04L1/00 ,  H04B7/04

    CPC分类号： H04B7/065 ,  H04B7/0452 ,  H04B7/0478 ,  H04B7/0639 ,  H04L1/0026 ,  H04L1/0029

    摘要： The present invention discloses method and terminal for feeding back channel state information. The method comprises: UE determining channel state information comprising first-type PMI and/or second-type PMI according to indication information, wherein first-type PMI is used for indicating index of one first precoding matrix in first precoding codebook, each first precoding matrix is used for mapping channel information of one wideband and/or long-term channel; second-type PMI is used for indicating index of one second precoding matrix in second precoding codebook, each second precoding matrix is used for mapping channel information of one subband and/or short-term channel; UE feeding back first-type PMI in PUCCH periodically and feeding back second-type PMI in PUSCH periodically or non-periodically, or, feeding back first-type PMI and second-type PMI in PUCCH. Through the present invention, precision of feeding back channel state information by UE is increased, and base station can dynamically select SU-MIMO or MU-MIMO transmission.

    摘要翻译： 本发明公开了用于反馈信道状态信息的方法和终端。 该方法包括：UE根据指示信息确定包括第一类型PMI和/或第二类型PMI的信道状态信息，其中第一类型PMI用于指示第一预编码码本中的一个第一预编码矩阵的索引，每个第一预编码矩阵 用于映射一个宽带和/或长期信道的信道信息; 第二类型PMI用于指示第二预编码码本中的一秒预编码矩阵的索引，每个第二预编码矩阵用于映射一个子带和/或短期信道的信道信息; UE周期性地在PUCCH中反馈第一类型PMI，并在PUSCH周期性或非周期性地反馈第二类型PMI，或者在PUCCH中反馈第一类型PMI和第二类型PMI。 通过本发明，UE的反馈信道状态信息的精度提高，基站能动态选择SU-MIMO或MU-MIMO传输。

    AD EXTENSIONS ON CONTENT NETWORK
    8.
    发明申请
    AD EXTENSIONS ON CONTENT NETWORK 有权
    AD扩展内容网络

    公开(公告)号：US20150254733A1

    公开(公告)日：2015-09-10

    申请号：US13669036

    申请日：2012-11-05

    申请人： Amy WU ,  Brandon Murdock Pearcy ,  Nathan Peter Lucash ,  Jun Xu ,  Yi Zhang ,  Zhen Yu

    发明人： Amy WU ,  Brandon Murdock Pearcy ,  Nathan Peter Lucash ,  Jun Xu ,  Yi Zhang ,  Zhen Yu

    IPC分类号： G06Q30/02 ,  G06F17/21 ,  G06F3/0481

    CPC分类号： G06Q30/0277 ,  G06F3/0482 ,  G06F3/04842 ,  G06F17/211 ,  G06T3/40

    摘要： A method of providing an ad extension includes selecting an advertisement for display. The method also includes selecting additional information related to the advertisement. The method also includes transmitting data representing the advertisement to a browser. The browser interacts with an expandable API to render an inline frame having an advertisement slot. The browser renders and displays the advertisement in the frame. The method also includes transmitting display data representing the additional information related to the advertisement to the browser. The browser receives an input to activate the ad extension. In response to the input, the browser interacts with the expandable API system to expand and render the frame. The browser renders, in the frame, the advertisement slot containing the advertisement. The browser also renders, in the frame, the additional information. The browser displays the expanded inline frame, such that the displayed frame covers a portion of the content.

    摘要翻译： 提供广告扩展的方法包括选择要显示的广告。 该方法还包括选择与该广告相关的附加信息。 该方法还包括将表示广告的数据发送到浏览器。 浏览器与可扩展API交互，以呈现具有广告位的内联框架。 浏览器在框架中呈现和显示广告。 该方法还包括将表示与广告相关的附加信息的显示数据发送到浏览器。 浏览器接收到一个输入以激活广告扩展。 响应于输入，浏览器与可扩展API系统交互以展开和渲染框架。 浏览器在框架中呈现包含广告的广告位。 浏览器还在框架中呈现附加信息。 浏览器显示扩展的内联框架，使得所显示的框架覆盖内容的一部分。

    Method and system of providing link adaptation for maximizing throughput in mobile satellite systems
    10.
    发明授权
    Method and system of providing link adaptation for maximizing throughput in mobile satellite systems 有权
    提供链路自适应的方法和系统，以最大限度地提高移动卫星系统的吞吐量

    公开(公告)号：US09088335B2

    公开(公告)日：2015-07-21

    申请号：US13586561

    申请日：2012-08-15

    申请人： Je-Hong Jong ,  Jun Xu ,  Channasandra Ravishankar

    发明人： Je-Hong Jong ,  Jun Xu ,  Channasandra Ravishankar

    IPC分类号： H04B7/185

    CPC分类号： H04B7/18513

    摘要： Various approaches are introduced to provide link adaptation to maximize the resource utilization of the satellite network: (i) a method to adapt the transmission rate for packet voice and data traffics; (ii) a method to control the transmit power of packet voice and data channels; and (iii) a method to accomplish the feedback loop in a secured and correct manner.

    摘要翻译： 引入各种方法以提供链路适应以最大化卫星网络的资源利用率：（i）适应分组语音和数据业务的传输速率的方法; （ii）控制分组话音和数据信道的发射功率的方法; 和（iii）以安全和正确的方式完成反馈回路的方法。