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公开(公告)号：US20120295297A1
公开(公告)日：2012-11-22
申请号：US13473901
申请日：2012-05-17
申请人： Sunghoon KWON , Su Eun CHUNG , Sung Hoon LEE , Wook PARK , Young Hoon SONG , Ji Sung JANG , Hyoki KIM , Howon LEE
发明人： Sunghoon KWON , Su Eun CHUNG , Sung Hoon LEE , Wook PARK , Young Hoon SONG , Ji Sung JANG , Hyoki KIM , Howon LEE
CPC分类号： G01N33/585 , G01N33/54313 , Y10T436/143333
摘要： Provided is an assay method using an encoded particle-based platform. In the assay method, first, a plurality of encoded particles having codes distinguishable from one another according to kinds of included target materials are prepared. The plurality of encoded particles are provided onto a plate including a plurality of wells by pipetting, and disposed in the plurality of wells by a self-assembly method. An analyte is provided into the plurality of wells. The codes of the plurality of encoded particles disposed in the plurality of wells are decoded. The target materials of the plurality of encoded particles are released to cause a reaction between the target materials and the analyte.
摘要翻译： 提供了使用编码的基于粒子的平台的测定方法。 在测定方法中，首先，准备具有根据所包含的目标材料的种类彼此可区分的代码的多个编码粒子。 通过移液将多个编码粒子提供到包括多个孔的板上，并通过自组装方法设置在多个孔中。 分析物被提供到多个孔中。 解码设置在多个孔中的多个编码粒子的代码。 多个编码粒子的目标材料被释放以引起目标材料和分析物之间的反应。
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公开(公告)号：US09492969B2
公开(公告)日：2016-11-15
申请号：US13149773
申请日：2011-05-31
申请人： Christopher M. Spadaccini , George Farquar , Todd Weisgraber , Steven Gemberling , Nicholas Fang , Jun Xu , Matthew Alonso , Howon Lee
发明人： Christopher M. Spadaccini , George Farquar , Todd Weisgraber , Steven Gemberling , Nicholas Fang , Jun Xu , Matthew Alonso , Howon Lee
IPC分类号： G03H1/02 , B29C67/00 , G02B1/00 , G02B5/00 , G02B27/56 , G03H1/00 , G03H1/22 , G03F7/20 , B33Y30/00 , B33Y10/00
CPC分类号： B29C67/0066 , B29C64/124 , B29C64/135 , B33Y10/00 , B33Y30/00 , G02B1/002 , G02B1/007 , G02B5/008 , G02B27/56 , G03F7/70408 , G03F7/70416 , G03H1/0005 , G03H1/0476 , G03H1/2294 , G03H2001/0094 , G03H2001/0482 , G03H2223/17 , G03H2225/60
摘要： A high-resolution PμSL system and method incorporating one or more of the following features with a standard PμSL system using a SLM projected digital image to form components in a stereolithographic bath: a far-field superlens for producing sub-diffraction-limited features, multiple spatial light modulators (SLM) to generate spatially-controlled three-dimensional interference holograms with nanoscale features, and the integration of microfluidic components into the resin bath of a PμSL system to fabricate microstructures of different materials.
摘要翻译： 高分辨率PμSL系统和方法将一个或多个以下特征与标准PμSL系统结合使用SLM投影数字图像以在立体溶液浴中形成组件：用于产生亚衍射限制特征的多场超声 空间光调制器（SLM），以产生具有纳米尺度特征的空间控制的三维干涉全息图，以及将微流体成分整合到PμSL系统的树脂浴中，以制造不同材料的微结构。
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公开(公告)号：US09482726B2
公开(公告)日：2016-11-01
申请号：US13039611
申请日：2011-03-03
申请人： Sunghoon Kwon , Hyoki Kim , Junhoi Kim , Howon Lee
发明人： Sunghoon Kwon , Hyoki Kim , Junhoi Kim , Howon Lee
CPC分类号： G01R33/1269 , B05D3/067 , B05D3/207 , G01R33/1276
摘要： Provided is a method of fabricating a magnetic axis-controlled structure. The method of fabricating a magnetic axis-controlled structure includes providing a composition including magnetic nanoparticles dispersed in a liquid medium, applying a magnetic field to the composition to align the magnetic nanoparticles along the magnetic field and form a magnetic axis, and solidifying the liquid medium to fix the magnetic axis.
摘要翻译： 提供一种制造磁轴控制结构的方法。 制造磁轴控制结构的方法包括提供包括分散在液体介质中的磁性纳米颗粒的组合物，向组合物施加磁场以使磁性纳米颗粒沿着磁场排列并形成磁轴，并使液体介质固化 以固定磁轴。
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公开(公告)号：US09328366B2
公开(公告)日：2016-05-03
申请号：US13524029
申请日：2012-06-15
申请人： Sunghoon Kwon , Hyoki Kim , Howon Lee , Sungsik Kim , Taehoon Ryu
发明人： Sunghoon Kwon , Hyoki Kim , Howon Lee , Sungsik Kim , Taehoon Ryu
CPC分类号： C12P19/34 , B01J2219/00315 , B01J2219/00441 , B01J2219/00468 , B01J2219/005 , B01J2219/00596 , B01J2219/00648 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , C40B20/02 , C40B50/14 , C40B60/04
摘要： Provided is a method of mass-producing high-purity nucleotides including providing a sequencing substrate having a clonal library of oligonucleotides on a solid support, sequencing the clonal library, obtaining measured location data of the solid support on the sequencing substrate, mapping pixel data of a signal generated from the solid support given as a result of the sequencing with the measured location data, extracting the solid support having a desired base sequence from the sequencing substrate using the mapping result, and amplifying an oligonucleotide on the extracted solid support to replicate on a large scale.
摘要翻译： 提供了批量生产高纯度核苷酸的方法，包括提供在固体支持物上具有寡核苷酸克隆文库的测序底物，测序克隆文库，获得测序底物上固体支持物的测量位置数据， 作为使用测量的位置数据进行测序的结果给出的固体支持物产生的信号，使用映射结果从测序底物中提取具有所需碱基序列的固体支持物，并扩增所提取的固体支持物上的寡核苷酸以复制 大规模。
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公开(公告)号：US10013647B2
公开(公告)日：2018-07-03
申请号：US13637467
申请日：2011-03-31
申请人： Sunghoon Kwon , Howon Lee , Junhoi Kim , Ji Yun Kim
发明人： Sunghoon Kwon , Howon Lee , Junhoi Kim , Ji Yun Kim
IPC分类号： G06K19/06 , B01J19/00 , B01L3/00 , G01N33/543 , G01N33/58 , G06K7/08 , G06K19/02 , B03C1/034 , B03C1/28 , G01N35/00
CPC分类号： G06K19/06196 , B01J19/0046 , B01J2219/00317 , B01J2219/00466 , B01J2219/00468 , B01J2219/005 , B01J2219/00533 , B01J2219/00545 , B01J2219/00549 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00655 , B01L3/502761 , B01L2200/0668 , B01L2300/0819 , B01L2300/0822 , B01L2400/043 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/24 , B03C2201/26 , G01N33/54346 , G01N33/587 , G01N35/0098 , G06K7/08 , G06K19/022
摘要： Provided is a method of magnetically controlling a magnetic structure, the method including: providing a solution containing magnetic structures, each including a magnetic axis in which magnetic nanoparticles are arranged; and controlling movements of the magnetic structures by applying an external magnetic field to the solution.
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公开(公告)号：US20170057162A1
公开(公告)日：2017-03-02
申请号：US15352051
申请日：2016-11-15
申请人： Christopher M. Spadaccini , Todd Weisgraber , George Farquar , Steven Gemberling , Nicholas Fang , Matthew Alonso , Jun Xu , Howon Lee
发明人： Christopher M. Spadaccini , Todd Weisgraber , George Farquar , Steven Gemberling , Nicholas Fang , Matthew Alonso , Jun Xu , Howon Lee
CPC分类号： G02B1/007 , B29C64/124 , B29C64/135 , B33Y10/00 , B33Y30/00 , G02B1/002 , G02B5/008 , G02B27/56 , G03F7/70408 , G03F7/70416 , G03H1/0005 , G03H1/0476 , G03H1/2294 , G03H2001/0094 , G03H2001/0482 , G03H2223/17 , G03H2225/60
摘要： A high-resolution PμSL system and method incorporating one or more of the following features with a standard PμSL system using a SLM projected digital image to form components in a stereolithographic bath: a far-field superlens for producing sub-diffraction-limited features, multiple spatial light modulators (SLM) to generate spatially-controlled three-dimensional interference holograms with nanoscale features, and the integration of microfluidic components into the resin bath of a PμSL system to fabricate microstructures of different materials.
摘要翻译： 高分辨率PμSL系统和方法将一个或多个以下特征与标准PμSL系统结合使用SLM投影数字图像以在立体溶液浴中形成组件：用于产生亚衍射限制特征的多场超声 空间光调制器（SLM），以产生具有纳米尺度特征的空间控制的三维干涉全息图，以及将微流体成分整合到PμSL系统的树脂浴中，以制造不同材料的微结构。
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公开(公告)号：US20150309473A1
公开(公告)日：2015-10-29
申请号：US13149773
申请日：2011-05-31
申请人： Christopher M. Spadaccini , George Farquar , Todd Weisgraber , Steven Gemberling , Nicholas Fang , Jun Xu , Matthew Alonso , Howon Lee
发明人： Christopher M. Spadaccini , George Farquar , Todd Weisgraber , Steven Gemberling , Nicholas Fang , Jun Xu , Matthew Alonso , Howon Lee
CPC分类号： B29C67/0066 , B29C64/124 , B29C64/135 , B33Y10/00 , B33Y30/00 , G02B1/002 , G02B1/007 , G02B5/008 , G02B27/56 , G03F7/70408 , G03F7/70416 , G03H1/0005 , G03H1/0476 , G03H1/2294 , G03H2001/0094 , G03H2001/0482 , G03H2223/17 , G03H2225/60
摘要： A high-resolution PμSL system and method incorporating one or more of the following features with a standard PμSL system using a SLM projected digital image to form components in a stereolithographic bath: a far-field superlens for producing sub-diffraction-limited features, multiple spatial light modulators (SLM) to generate spatially-controlled three-dimensional interference holograms with nanoscale features, and the integration of microfluidic components into the resin bath of a PμSL system to fabricate microstructures of different materials.
摘要翻译： 高分辨率PμSL系统和方法将一个或多个以下特征与标准PμSL系统结合使用SLM投影数字图像以在立体溶液浴中形成组件：用于产生亚衍射限制特征的多场超声 空间光调制器（SLM），以产生具有纳米尺度特征的空间控制的三维干涉全息图，以及将微流体成分整合到PμSL系统的树脂浴中，以制造不同材料的微结构。
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公开(公告)号：US20130109059A1
公开(公告)日：2013-05-02
申请号：US13524029
申请日：2012-06-15
申请人： Sunghoon KWON , Hyoki KIM , Howon LEE , Sungsik KIM , Taehoon RYU
发明人： Sunghoon KWON , Hyoki KIM , Howon LEE , Sungsik KIM , Taehoon RYU
CPC分类号： C12P19/34 , B01J2219/00315 , B01J2219/00441 , B01J2219/00468 , B01J2219/005 , B01J2219/00596 , B01J2219/00648 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , C40B20/02 , C40B50/14 , C40B60/04
摘要： Provided is a method of mass-producing high-purity nucleotides including providing a sequencing substrate having a clonal library of oligonucleotides on a solid support, sequencing the clonal library, obtaining measured location data of the solid support on the sequencing substrate, mapping pixel data of a signal generated from the solid support given as a result of the sequencing with the measured location data, extracting the solid support having a desired base sequence from the sequencing substrate using the mapping result, and amplifying an oligonucleotide on the extracted solid support to replicate on a large scale.
摘要翻译： 提供了批量生产高纯度核苷酸的方法，包括提供在固体支持物上具有寡核苷酸克隆文库的测序底物，测序克隆文库，获得测序底物上固体支持物的测量位置数据， 作为使用测量的位置数据进行测序的结果给出的固体支持物产生的信号，使用映射结果从测序底物中提取具有所需碱基序列的固体支持物，并扩增所提取的固体支持物上的寡核苷酸以复制 大规模。
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公开(公告)号：US09564261B2
公开(公告)日：2017-02-07
申请号：US13271656
申请日：2011-10-12
申请人： Sunghoon Kwon , Howon Lee , Junhoi Kim , Hyoki Kim
发明人： Sunghoon Kwon , Howon Lee , Junhoi Kim , Hyoki Kim
CPC分类号： H01F1/28 , B22F1/0003 , B22F1/02 , B22F2301/155 , B22F2301/35 , B22F2302/256 , B22F2999/00 , B82Y25/00 , H01F1/0054 , H01F1/0063 , B22F1/0018 , C22C2202/02 , B22F2301/15
摘要： Provided is a color encoding method including providing a composition including a liquid medium and magnetic nanoparticles dispersed in the liquid medium; applying a magnetic field to the composition to align the magnetic nanoparticles; and applying a patterned energy source to the composition to solidify the composition, wherein more than one region of the composition are sequentially solidified with varying magnetic field strength to fix a plurality of color codes.
摘要翻译： 提供一种颜色编码方法，包括提供包含分散在液体介质中的液体介质和磁性纳米颗粒的组合物; 向组合物施加磁场以对准磁性纳米颗粒; 以及将图案化的能量源施加到所述组合物以固化所述组合物，其中所述组合物的多于一个区域以不同的磁场强度依次固化以固定多个颜色代码。
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公开(公告)号：US20130105581A1
公开(公告)日：2013-05-02
申请号：US13637467
申请日：2011-03-31
申请人： Sunghoon Kwon , Howon Lee , Junhoi Kim , Ji Yun Kim
发明人： Sunghoon Kwon , Howon Lee , Junhoi Kim , Ji Yun Kim
CPC分类号： G06K19/06196 , B01J19/0046 , B01J2219/00317 , B01J2219/00466 , B01J2219/00468 , B01J2219/005 , B01J2219/00533 , B01J2219/00545 , B01J2219/00549 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00648 , B01J2219/00655 , B01L3/502761 , B01L2200/0668 , B01L2300/0819 , B01L2300/0822 , B01L2400/043 , B03C1/034 , B03C1/288 , B03C2201/18 , B03C2201/24 , B03C2201/26 , G01N33/54346 , G01N33/587 , G01N35/0098 , G06K7/08 , G06K19/022
摘要： Provided is a method of magnetically controlling a magnetic structure, the method including: providing a solution containing magnetic structures, each including a magnetic axis in which magnetic nanoparticles are arranged; and controlling movements of the magnetic structures by applying an external magnetic field to the solution.
摘要翻译： 提供一种磁性控制磁性结构的方法，所述方法包括：提供包含磁性结构的溶液，每个磁性结构包括其中布置有磁性纳米颗粒的磁轴; 以及通过向溶液施加外部磁场来控制磁性结构的移动。
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