公开(公告)号：US20180247435A1

公开(公告)日：2018-08-30

申请号：US15756119

申请日：2016-09-05

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Ehsan DEHGHAN MARVAST

IPC: G06T11/00 ,  A61B6/03 ,  A61B6/00 ,  A61B8/08 ,  A61B8/00

Abstract: A method for determining a surrogate respiratory signal for four-dimensional computed tomography using ultrasound data includes acquiring computed tomography data with a computed tomography imaging system (402), acquiring ultrasound data with an ultrasound probe of an ultrasound imaging system (404) concurrently with acquiring the computed tomography data during one or more respiratory cycles, wherein the ultrasound probe is aligned to acquire an image of a diaphragm of a subject, synchronizing the acquired computed tomography data and the acquired ultrasound data, and determining a surrogate respiratory signal from the acquired ultrasound data.

公开(公告)号：US20190209872A1

公开(公告)日：2019-07-11

申请号：US16326258

申请日：2017-08-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Robert Michael STARUCH ,  Shyam BHARAT ,  Shriram SETHURAMAN ,  Vijay PARTHASARATHY ,  Ajay ANAND ,  Ehsan DEHGHAN MARVAST

IPC: A61N7/02 ,  A61B5/01 ,  A61B8/08 ,  A61B5/00 ,  A61B5/055 ,  G01R33/48

CPC classification number: A61N7/02 ,  A61B5/0036 ,  A61B5/015 ,  A61B5/055 ,  A61B5/4836 ,  A61B5/4848 ,  A61B8/483 ,  A61B8/485 ,  A61B8/5261 ,  A61B90/04 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2017/00123 ,  A61B2017/00128 ,  A61B2018/00791 ,  A61B2018/00898 ,  A61B2034/101 ,  A61B2090/0472 ,  A61B2090/374 ,  A61B2090/378 ,  A61B2560/0276 ,  A61N2007/0039 ,  A61N2007/0052 ,  G01R33/4804 ,  G01R33/4814 ,  G01S7/52036 ,  G01S7/52042 ,  G01S15/8993

Abstract: A system (100) includes an imaging system (130), and a therapy control device (122). The imaging system (130) generates temperature maps (140) and strain maps (142) of localized tissues of a patient. The therapy control device (122) includes one or more computer processors configured to detect at least one failure mode (300, 302, 304, 400) of generated mild hyperthermia in the localized tissues of the patient according to at least one of the temperature maps, the strain maps, or a signal indicative of detected inertial cavitation. In some embodiments, the therapy control device either halts therapy or issues a warning.

公开(公告)号：US20180229053A1

公开(公告)日：2018-08-16

申请号：US15513608

申请日：2015-09-25

Applicant: Koninklijke Philips N.V.

Inventor： JOCHEN KRUECKER ,  Ehsan DEHGHAN MARVAST ,  Shyam BHARAT ,  Cynthia Ming-Fu KUNG

IPC: A61N5/10 ,  A61B6/03 ,  A61B8/08 ,  A61B34/20

CPC classification number: A61N5/1007 ,  A61B5/055 ,  A61B6/032 ,  A61B8/0841 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61N5/1027 ,  A61N5/1039 ,  A61N5/1048 ,  A61N5/1071 ,  A61N2005/1024

Abstract: A brachytherapy seed localization system for localizing radioactive seeds within a diseased tissue, the brachytherapy seed localization system employs a tool tracking machine (50) for generating a tracked seed distribution map (51) of delivered locations of the radioactive seeds within the diseased tissue, and a tissue imaging machine (60) for generating a seed distribution image (61) of projected locations of the radioactive seeds within the diseased tissue including at least one false projected location. The brachytherapy seed localization system further employs a brachytherapy seed localizer (70) for generating a composite seed distribution map (71) of estimated locations of the radioactive seeds within the diseased tissue derived from a combination of the tracked seed distribution map (51) and the seed distribution image (61) excluding any false projected location(s) within the seed distribution image (61).

公开(公告)号：US20180304100A1

公开(公告)日：2018-10-25

申请号：US15769078

申请日：2016-10-13

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Shyam BHARAT ,  Ajay ANAND ,  Robert Michael STARUCH ,  Shriram SETHURAMAN ,  Vijay PARTHASARATHY ,  Ehsan DEHGHAN MARVAST

IPC: A61N5/10 ,  A61N7/02

CPC classification number: A61N5/1048 ,  A61N5/1031 ,  A61N5/1037 ,  A61N5/1038 ,  A61N5/1039 ,  A61N7/02 ,  A61N2005/1087

Abstract: A method includes generating a hyperthermia heat plan for tissue of interest, generating a hyperthermia adapted radiation therapy plan for the tissue of interest, controlling a heat source (126) to deliver heat to the tissue of interest according to the hyperthermia heat plan, and controlling a radiation source of a radiation therapy system (100) to deliver radiation to the tissue of interest according to the hyperthermia adapted radiation therapy plan. A system includes a radiation treatment planner (124) configured to generate a hyperthermia adapted radiation therapy plan for the tissue of interest, a radiation therapy system (100) configured to deliver radiation in accordance with the hyperthermia adapted radiation therapy plan, and a hyperthermia heat delivery system (126) configured to deliver heat in accordance with a hyperthermia plan.

公开(公告)号：US20160236009A1

公开(公告)日：2016-08-18

申请号：US15027317

申请日：2014-10-09

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Jörg SABCZYNSKI ,  Bharat RAMACHANDRAN ,  Ehsan DEHGHAN MARVAST ,  Weihua ZHOU

IPC: A61N5/10

CPC classification number: A61N5/1037 ,  A61B5/055 ,  A61B5/103 ,  A61B5/113 ,  A61B6/032 ,  A61N5/10 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1077 ,  A61N2005/1057 ,  A61N2005/1059

Abstract: There is presented a method 100 and apparatus 200 to measure the surface of the patient (thorax and abdominal regions), e.g., during therapy delivery and (if necessary) while imaging. Together with biomechanical considerations the position of internal structures of the patient, such as an organ, and optionally a tumor in an organ, is inferred from the measured patient surface. In case the patient breaths and thus the organ and/or tumor moves, the position may be determined, which may be advantageous during, e.g., radiation therapy, since it enables that whenever the tumor is at the right position according to the radiation therapy plan, the radiation is switched on. In a specific embodiment, a finite element model is employed.

Abstract translation: 提出了方法100和装置200来测量患者（胸部和腹部区域）的表面，例如在治疗递送期间和（如果需要）成像时）。 与生物力学考虑一起，从测量的患者表面推断患者内部结构的位置，例如器官和任选的器官中的肿瘤。 如果患者呼吸并因此器官和/或肿瘤移动，则可以确定位置，其在例如放射治疗期间可能是有利的，因为它可以使肿瘤根据放射治疗计划处于正确位置 ，辐射被打开。 在具体实施例中，采用有限元模型。