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    Novel phospholipases and uses thereof
    1.
    发明申请
    Novel phospholipases and uses thereof 失效
    新型磷脂酶及其用途

    公开(公告)号：US20100047877A1

    公开(公告)日：2010-02-25

    申请号：US12461287

    申请日：2009-08-06

    申请人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Bernhard Meima

    发明人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Bernhard Meima

    IPC分类号： C12N15/52 ,  C12N15/80 ,  C12N1/15 ,  C12P19/34 ,  C12N15/64 ,  C12P21/02

    CPC分类号： A21D8/042 ,  C07K2319/00 ,  C12N9/20

    摘要： The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.

    摘要翻译： 本发明涉及新鉴定的多核苷酸序列，其包含编码从黑曲霉分离的新型磷脂酶的基因。 本发明的特征在于新基因的全长核苷酸序列，cDNA序列包含新型磷脂酶的全长编码序列以及全长功能蛋白的氨基酸序列及其功能等同物。 本发明还涉及在工业过程中使用这些酶的方法和诊断真菌感染的方法。 本发明还包括用根据本发明的多核苷酸转化的细胞和其中根据本发明的磷脂酶被遗传修饰以增强或降低其活性和/或表达水平的细胞。

    Phospholipases and uses thereof
    2.
    发明授权
    Phospholipases and uses thereof 失效
    磷脂酶及其用途

    公开(公告)号：US07588925B2

    公开(公告)日：2009-09-15

    申请号：US11544679

    申请日：2006-10-10

    申请人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Bernhard Meima

    发明人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Bernhard Meima

    IPC分类号： A21D2/00 ,  C12N9/20 ,  A23C9/12 ,  C12N1/00 ,  C12N9/16 ,  C07H21/04

    CPC分类号： A21D8/042 ,  C07K2319/00 ,  C12N9/20

    摘要： The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.

    摘要翻译： 本发明涉及新鉴定的多核苷酸序列，其包含编码从黑曲霉分离的新型磷脂酶的基因。 本发明的特征在于新基因的全长核苷酸序列，cDNA序列包含新型磷脂酶的全长编码序列以及全长功能蛋白的氨基酸序列及其功能等同物。 本发明还涉及在工业过程中使用这些酶的方法和诊断真菌感染的方法。 本发明还包括用根据本发明的多核苷酸转化的细胞和其中根据本发明的磷脂酶被遗传修饰以增强或降低其活性和/或表达水平的细胞。

    Phospholipases and uses thereof
    3.
    发明授权
    Phospholipases and uses thereof 失效
    磷脂酶及其用途

    公开(公告)号：US07838274B2

    公开(公告)日：2010-11-23

    申请号：US12461287

    申请日：2009-08-06

    申请人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Bernhard Meima

    发明人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Bernhard Meima

    IPC分类号： C12N9/16 ,  C12N1/20 ,  C12N15/00 ,  C12N9/18 ,  C07H21/04 ,  C12P21/06

    CPC分类号： A21D8/042 ,  C07K2319/00 ,  C12N9/20

    摘要： The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.

    摘要翻译： 本发明涉及新鉴定的多核苷酸序列，其包含编码从黑曲霉分离的新型磷脂酶的基因。 本发明的特征在于新基因的全长核苷酸序列，cDNA序列包含新型磷脂酶的全长编码序列以及全长功能蛋白的氨基酸序列及其功能等同物。 本发明还涉及在工业过程中使用这些酶的方法和诊断真菌感染的方法。 本发明还包括用根据本发明的多核苷酸转化的细胞和其中根据本发明的磷脂酶被遗传修饰以增强或降低其活性和/或表达水平的细胞。

    Novel phospholipases and uses thereof
    4.
    发明申请
    Novel phospholipases and uses thereof 失效
    新型磷脂酶及其用途

    公开(公告)号：US20070207521A1

    公开(公告)日：2007-09-06

    申请号：US11544679

    申请日：2006-10-10

    申请人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Meima

    发明人： Kaj Albermann ,  Wolfram Kemmner ,  Dieter Maier ,  Fabio Spreafico ,  Alexander Stock ,  Christian Wagner ,  Lex De Boer ,  Roelf Meima

    IPC分类号： C12P21/06 ,  C07H21/04 ,  C12N9/16 ,  C12N1/16 ,  C12N15/74

    CPC分类号： A21D8/042 ,  C07K2319/00 ,  C12N9/20

    摘要： The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.

    摘要翻译： 本发明涉及新鉴定的多核苷酸序列，其包含编码从黑曲霉分离的新型磷脂酶的基因。 本发明的特征在于新基因的全长核苷酸序列，cDNA序列包含新型磷脂酶的全长编码序列以及全长功能蛋白的氨基酸序列及其功能等同物。 本发明还涉及在工业过程中使用这些酶的方法和诊断真菌感染的方法。 本发明还包括用根据本发明的多核苷酸转化的细胞和其中根据本发明的磷脂酶被遗传修饰以增强或降低其活性和/或表达水平的细胞。