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    Atrioventricular valve tissue ablation catheter and method
    1.
    发明授权
    Atrioventricular valve tissue ablation catheter and method 失效
    房室瓣膜组织消融导管及方法

    公开(公告)号：US5823955A

    公开(公告)日：1998-10-20

    申请号：US559672

    申请日：1995-11-20

    申请人： Karl Heinz Kuck ,  Frank Nguyen

    发明人： Karl Heinz Kuck ,  Frank Nguyen

    IPC分类号： A61B18/14 ,  A61N1/05 ,  A61N1/40 ,  A61B5/04 ,  A61N1/36

    CPC分类号： A61B18/1492 ,  A61N1/056 ,  A61N1/403 ,  A61B2018/00369 ,  A61B2018/00654 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2018/00952

    摘要： An atrioventricular valve tissue ablation catheter (2), especially suited for treating Mahaim fibers, includes a shaft (4) with a deflectable tip (20) at the distal end (6) and a handle (10) at the proximal end (8). The tip includes a distal segment (66) curving in one direction and a proximal segment (44) curving in the opposite direction so the distal segment causes the distal segment can engage tissue on either side of the annulus (92) of the tricuspid (or mitral) valve (90). Ablation energy can be supplied through the ablation electrodes (46, 70) simultaneously or one at a time to ablate tissue at the annulus without the need for moving the catheter. Mapping electrodes (38) are provided proximal of the ablation electrodes.

    摘要翻译： 特别适用于治疗马赫姆纤维的房室瓣膜组织消融导管（2）包括在远端（6）处具有可偏转尖端（20）的轴（4）和近端（8）处的手柄（10） 。 尖端包括在一个方向上弯曲的远端段（66）和沿相反方向弯曲的近端段（44），使得远端区段使得远侧段可以接合三尖瓣环（92）的任一侧上的组织（或 二尖瓣）（90）。 消融能量可以通过消融电极（46,70）同时或一次一次地供应，以消除环空中的组织，而不需要移动导管。 映射电极（38）设置在消融电极的近侧。

    Steerable catheter with a control handle having a pulley mechanism
    4.
    发明授权
    Steerable catheter with a control handle having a pulley mechanism 有权

    公开(公告)号：US06522933B2

    公开(公告)日：2003-02-18

    申请号：US09822087

    申请日：2001-03-30

    申请人： Frank Nguyen

    发明人： Frank Nguyen

    IPC分类号： A61N100

    CPC分类号： A61M25/0136

    摘要： A steerable catheter is provided. The catheter comprises an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending therethrough and a control handle at the proximal end of the catheter body. The control handle comprises a handle housing having a generally hollow interior and fixedly attached, either directly or indirectly to the catheter body; a piston slidably mounted in the handle housing and having proximal and distal ends; and a pulley fixedly attached, either directly or indirectly to the handle housing at a location proximal to the proximal end of the piston. A first puller wire is provided having a distal end fixedly attached in the distal end of the catheter body and a proximal end anchored to the piston. A second puller wire is provided having a distal end fixedly attached in the distal end of the catheter body. The second puller wire extends through the catheter body, into the handle, and around the pulley, and the proximal end of the second puller wire is anchored to the piston.

    Asymmetrical bidirectional steerable catheter
    6.
    发明授权
    Asymmetrical bidirectional steerable catheter 有权

    公开(公告)号：US06551271B2

    公开(公告)日：2003-04-22

    申请号：US09846732

    申请日：2001-04-30

    申请人： Frank Nguyen

    发明人： Frank Nguyen

    IPC分类号： A61M3700

    CPC分类号： A61B18/1492 ,  A61B34/20 ,  A61B2017/00053 ,  A61B2017/003 ,  A61B2034/2051

    摘要： A bidirectional steerable catheter is provided that can be deflected to form two different curves, i.e., two curves each having a different radius of curvature. The catheter comprises an elongated, flexible tubular catheter body having proximal and distal ends and a lumen extending therethrough. A tip section is provided at the distal end of the catheter body. The tip section comprises a flexible plastic tubing having at least first and second off-axis lumens extending therethrough. A control handle is attached to the proximal end of the catheter body. A first puller wire extends through the lumen of the catheter body and the first off-axis lumen of the tip section. The first puller wire has a distal end anchored in the tip section and a proximal end anchored to the control handle. A second puller wire extends through the lumen of the catheter body and the second off-axis lumen of the tip section. The second puller wire has a distal end anchored in the tip section and a proximal end anchored to the control handle. A first compression coil extends through the lumen of the catheter body in surrounding relation to the first puller wire. The first compression coil has a distal end anchored in the catheter body or in the first off-axis lumen of the tip section at a first anchor position. A second compression coil extends through the lumen of the catheter body in surrounding relation to the second puller wire and into the second off-axis lumen. The second compression coil has a distal end anchored in the second off-axis lumen of the tip section at a second anchor position that is distal to the first anchor position. By this design, the radius of curvature of each curve achieved by deflection of the tip section is controlled by the anchor position of the compression coil surrounding the appropriate puller wire.

    Steerable electrophysiology catheter
    7.
    发明授权
    Steerable electrophysiology catheter 失效
    导向电生理导管

    公开(公告)号：US5545200A

    公开(公告)日：1996-08-13

    申请号：US343310

    申请日：1994-11-22

    申请人： Scott H. West ,  Frank Nguyen

    发明人： Scott H. West ,  Frank Nguyen

    IPC分类号： A61B18/14 ,  A61M25/01 ,  A61N1/05 ,  A61M1/00 ,  A61B17/38

    CPC分类号： A61M25/0144 ,  A61B18/1492 ,  A61M25/0136 ,  A61M25/0147 ,  A61N1/056 ,  A61B2017/003 ,  A61B2018/00065 ,  A61B2018/00357 ,  A61B2018/00392 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/0091 ,  A61B2018/00946 ,  A61B2018/00952 ,  A61B2018/126 ,  A61B2018/1435 ,  A61B2018/1472 ,  A61B2218/002 ,  A61M2025/0063 ,  A61M2025/015 ,  A61M2025/0161 ,  A61M25/0141

    摘要： An electrophysiology catheter (20) comprises a shaft (22) having a first bending stiffness and a deflectable tip (28) secured to the distal end (24) of the shaft with a second bending stiffness less than the first bending stiffness. At least one electrode (34, 36) is mounted to the tip for delivering current to or monitoring electrical activity of tissue. A manipulator wire (58) is coupled to the distal end of the deflectable tip, whereby the deflectable tip may be deflected by axial force applied to the manipulator wire. A stiffener member (66) is axially slidable relative to the tip so as to adjust the tip curvature without removing the catheter from the body. The catheter may further include a core wire (72) configured to rotate the deflectable tip about a longitudinal axis (2) without rotating the proximal end (26) of the catheter shaft, wherein the distal end of the deflectable tip remains in a substantially constant axial position, preferably in a plane perpendicular to the longitudinal axis.

    摘要翻译： 电生理学导管（20）包括具有第一弯曲刚度的轴（22）和固定到所述轴的远端（24）的可偏转尖端（28），其具有小于所述第一弯曲刚度的第二弯曲刚度。 至少一个电极（34,36）安装到尖端以将电流传送到或监测组织的电活动。 操纵杆（58）联接到可偏转尖端的远端，由此通过施加到机械手线的轴向力，可偏转尖端可能被偏转。 加强件（66）相对于尖端可轴向滑动，以便调节尖端曲率而不从体内移除导管。 该导管还可以包括芯线（72），该芯线被构造成围绕纵向轴线（2）旋转可偏转尖端，而不旋转导管轴的近端（26），其中可偏转尖端的远端保持基本上恒定 优选地在垂直于纵向轴线的平面中。

    Surgical Puncture Cinch and Closure System
    8.
    发明申请
    Surgical Puncture Cinch and Closure System 有权
    手术穿刺闭合系统

    公开(公告)号：US20110028995A1

    公开(公告)日：2011-02-03

    申请号：US12844139

    申请日：2010-07-27

    申请人： Manouchehr Miraki ,  Yoon H. Kwon ,  Frank Nguyen

    发明人： Manouchehr Miraki ,  Yoon H. Kwon ,  Frank Nguyen

    IPC分类号： A61B17/04

    CPC分类号： A61B17/06109 ,  A61B17/0482 ,  A61B17/0483 ,  A61B17/06119 ,  A61B2017/00243 ,  A61B2017/003 ,  A61B2017/0406 ,  A61B2017/06052 ,  A61B2017/06076 ,  A61B2017/06095 ,  A61B2090/036 ,  A61F2/2409

    摘要： A system for forming a purse string suture, including a suture applicator having a proximal handle having a suture spool mounted thereon or in an internal chamber. A length of suture is partly wound on the spool, and a hollow suture needle extends from a distal end of the handle and contains a free end of the length of suture. The suture needle projects distally from the handle in a helical shape and terminates in a sharp distal tip with an opening in one side close to the distal tip. The free end of the length of suture may extend out of the distal tip and back into the hollow suture needle through the opening. The suture needle may have a deflection segment adjacent the distal tip that is more flexible than the rest of the helical distal portion of the suture needle. A linear hollow pivot shaft extends from a distal end of the handle substantially along an axis of the helical distal portion of the suture needle. The pivot shaft has a blunt tip with a substantially larger radial profile than the shaft to prevent puncturing tissue.

    摘要翻译： 一种用于形成钱包缝合线的系统，包括缝合线施加器，其具有近端手柄，其具有安装在其上的缝合线轴或内部腔室。 一段缝合线部分地卷绕在线轴上，并且中空缝合针从手柄的远端延伸并且包含缝合长度的自由端。 缝合针从手柄向远端突出呈螺旋状，终止于尖锐的远端，其一侧的开口靠近远端。 缝线长度的自由端可以延伸出远端，并通过开口返回中空缝合针。 缝合针可以具有与远侧末端相邻的偏转部分，其比缝合针的螺旋形远端部分的其余部分更柔性。 线性中空枢转轴基本上沿着缝合针的螺旋形远端部分的轴线从手柄的远端延伸。 枢转轴具有钝头，其具有比轴大得多的径向轮廓以防止穿刺组织。

    Method for ablation of heart tissue
    10.
    发明授权
    Method for ablation of heart tissue 有权
    心脏组织消融方法

    公开(公告)号：US6156034A

    公开(公告)日：2000-12-05

    申请号：US218769

    申请日：1998-12-22

    申请人： Francisco G. Cosio ,  Frank Nguyen ,  Mark A. Maguire

    发明人： Francisco G. Cosio ,  Frank Nguyen ,  Mark A. Maguire

    IPC分类号： A61B18/14 ,  A61M25/00 ,  A61M25/01 ,  A61B5/042

    CPC分类号： A61M25/0141 ,  A61M25/0144 ,  A61M25/0147 ,  A61B18/14 ,  A61B2018/00946 ,  A61B2018/00952 ,  A61M2025/015 ,  A61M2025/0161 ,  A61M25/0054

    摘要： A dual curve ablation catheter (2), especially suited for treating atrial flutter, includes a shaft (4) with a deflectable tip (20) at the distal end (6) and a handle (10) at the proximal end (8). The tip includes a highly flexible distal segment (30), a relatively stiff intermediate segment (28) and a flexible proximal segment (26) so that pulling on a manipulator wire (16) attached to the distal segment causes the distal segment to curve and engage, for example, an isthmus of tissue (106) adjacent the tricuspid valve (104) and the inferior vena cava (98) and causes the proximal segment to curve and press against the wall (110) of the inferior vena cava so to stabilize the catheter. Ablation energy can be supplied through the ablation electrodes (48, 68) simultaneously or one at a time to ablate tissue at the isthmus without the need for moving the catheter.

    摘要翻译： 特别适用于治疗心房扑动的双曲线消融导管（2）包括在远端（6）处具有可偏转尖端（20）的轴（4）和在近端（8）处的手柄（10）。 尖端包括高度柔性的远侧段（30），相对刚性的中间段（28）和柔性近端段（26），使得牵引附接到远端段的操纵杆（16）导致远端段弯曲，并且 接合例如邻近三尖瓣（104）和下腔静脉（98）的组织（106）的峡部，并使近端段弯曲并压靠下腔静脉的壁（110）以便稳定 导管。 可以同时或一次一次地通过消融电极（51,68）提供消融能量以在峡部上烧蚀组织，而不需要移动导管。