摘要:
Provided is an optical compensation film comprising a support, an alignment layer, and an optically anisotropic layer formed of a liquid crystal composition in this order, said support being a cyclic polyolefin polymer film having a surface thereof subjected to corona discharge treatment or atmospheric pressure plasma treatment, wherein said alignment layer is disposed in contact with said treated surface of said support, said liquid crystal composition comprises a radical polymerization initiator capable of generating a halogen radical or a hydrocarbon radical having atoms other than hydrogen atom of the number equal to or smaller than 8, and said optically anisotropic layer is a layer formed by curing said liquid crystal composition on said alignment layer via polymerization.
摘要:
To provide a novel and excellent method for treating and/or preventing prostatic cancer, benign prostatic hyperplasia, acne, seborrhea, hirsutism, baldness, alopecia, precocious puberty, adrenal hypertrophy, polycystic ovary syndrome, breast cancer, lung cancer, endometriosis, leiomyoma and the like based on selective inhibitory activity against 17βHSD type 5.It was found that an N-sulfonylindole derivative, where the indole ring is substituted by a carboxy group, a carboxy-substituted lower alkyl group or a carboxy-substituted lower alkenyl group at its carbon atom, has potent selective inhibitory activity against 17βHSD type 5 and may become a therapeutic agent and/or preventive agent for benign prostatic hyperplasia, prostatic cancer and the like without accompanying adverse drug reactions due to a decrease in testosterone, and the present invention has thus been completed.
摘要:
A combination grinding machine grinds a plurality of axially arranged portions of a workpiece by use of a grinding wheel supported rotatably on a first wheel head and a superfinishing wheel supported rotatably on a second wheel head. A numerical control unit controls feed units for the first and second wheel heads in order to move the first and second wheel heads independently of each other in the axial direction of the workpiece and in the direction perpendicular to the axial direction, such that each of the axially arranged portions is ground by the grinding wheel, and simultaneously with this, another ground portion is superfinished by the superfinishing wheel.
摘要:
A polymeric membrane having maleic anhydride residues which comprises a blend of a maleic anhydride copolymer and a support polymer, said blend being partially cross-linked with a bifunctional cross-linking reagent. When hydrolyzed, this membrane turns into an ion exchange membrane or a membrane on which an enzyme is immobilized.
摘要:
A suction puncture device includes a puncture needle having an outer tube that has an opening edge of a first front end formed in the shape of a blade, and a stopper member that has a second front end disposed within the outer tube at a position separated from the first front end of the outer tube by a predetermined distance. A sample containing portion is formed between the second front end of the stopper member and the first front end of the outer tube. A ventilation passage is formed around the stopper member within the outer tube, a suction unit is connected to a first base end side of the outer tube, and the suction unit is communicated with and connected to the sample containing portion via the ventilation passage.
摘要:
To provide a novel and excellent method for treating and/or preventing prostatic cancer, benign prostatic hyperplasia, acne, seborrhea, hirsutism, baldness, alopecia, precocious puberty, adrenal hypertrophy, polycystic ovary syndrome, breast cancer, lung cancer, endometriosis, leiomyoma and the like based on selective inhibitory activity against 17βHSD type 5.It was found that an N-sulfonylindole derivative, where the indole ring is substituted by a carboxy group, a carboxy-substituted lower alkyl group or a carboxy-substituted lower alkenyl group at its carbon atom, has potent selective inhibitory activity against 17βHSD type 5 and may become a therapeutic agent and/or preventive agent for benign prostatic hyperplasia, prostatic cancer and the like without accompanying adverse drug reactions due to a decrease in testosterone, and the present invention has thus been completed.
摘要:
To provide a novel and excellent method for treating and/or preventing prostatic cancer, benign prostatic hyperplasia, acne, seborrhea, hirsutism, baldness, alopecia, precocious puberty, adrenal hypertrophy, polycystic ovary syndrome, breast cancer, lung cancer, endometriosis, leiomyoma and the like based on selective inhibitory activity against 17βHSD type 5.It was found that an N-sulfonylindole derivative, where the indole ring is substituted by a carboxy group, a carboxy-substituted lower alkyl group or a carboxy-substituted lower alkenyl group at its carbon atom, has potent selective inhibitory activity against 17βHSD type 5 and may become a therapeutic agent and/or preventive agent for benign prostatic hyperplasia, prostatic cancer and the like without accompanying adverse drug reactions due to a decrease in testosterone, and the present invention has thus been completed.
摘要:
A crown ether compound is shown below and useful as a separating agent for chemical compounds. ##STR1## (In the formula, A and B represent hydrogen atoms, straight chain or branched alkyl groups having 1-6 carbon atoms, allyl groups having 6-10 carbon atoms, or aralkyl groups having 7-9 carbon atoms. Although A and B may be different groups, it is preferable that they be the same.R.sub.1 represents a hydrogen atom, a straight chain or branched alkyl group having 1-20 carbon atoms, or preferably an alkyl group having 6-16 carbon atoms. R.sub.1 may be bonded to any carbon atom on the cyclical ester group and its number is 1-12, and preferably 1-3. n represents an integer from 3-10, and preferably 4-8, with 5 or 6 being even more preferable.In addition R.sub.2 and R.sub.3 represent straight chain or branched alkyl groups having 1-30, and preferably 6-20 carbon atoms, or aryl groups having 6-18 carbon atoms, or aralkyl groups having 7-30 carbon atoms. The location of R.sub.2 and R.sub.3 may be anywhere other than the A and B substitution positions on the condensed ring, and although one of each of R.sub.2 and R.sub.3 is satisfactory, a maximum of 5 groups may be substituted. In addition, R.sub.2 and R.sub.3 may also be different.)
摘要:
A filler for separating an optical isomer comprising a surface-hydrophobic filler component and an optically active lipophilic crown compound carried on the filler component by adsorption. The filler may be charged in a column to carry out separation of a sample such as amino acid or the like in the form of an aqueous solution.