公开(公告)号：US09166142B2

公开(公告)日：2015-10-20

申请号：US13567157

申请日：2012-08-06

Applicant: Fumimasa Horikiri ,  Kenji Shibata ,  Kazufumi Suenaga ,  Kazutoshi Watanabe ,  Akira Nomoto

Inventor： Fumimasa Horikiri ,  Kenji Shibata ,  Kazufumi Suenaga ,  Kazutoshi Watanabe ,  Akira Nomoto

IPC: H01L41/332 ,  H01L41/08 ,  H01L41/047 ,  H01G5/18 ,  H01L41/09 ,  H01L41/187

CPC classification number: H01L41/332 ,  H01G5/18 ,  H01L41/047 ,  H01L41/0477 ,  H01L41/0805 ,  H01L41/094 ,  H01L41/1873

Abstract: A manufacturing method of a piezoelectric film element includes forming a piezoelectric film including a lead-free alkali niobate based compound having a perovskite structure represented by a compositional formula of (K1-XNaX)NbO3 on a substrate, and dry-etching the piezoelectric film by using a low-pressure plasma including a fluorine system reactive gas.

Abstract translation: 压电薄膜元件的制造方法包括在基板上形成具有由（K1-XNaX）NbO3组成式表示的钙钛矿结构的无铅碱铌酸酯系化合物的压电膜，并通过以下方式对压电膜进行干法蚀刻 使用包含氟系反应气体的低压等离子体。

公开(公告)号：US08860286B2

公开(公告)日：2014-10-14

申请号：US13577405

申请日：2011-02-15

Applicant: Kazufumi Suenaga ,  Kenji Shibata ,  Kazutoshi Watanabe ,  Akira Nomoto

Inventor： Kazufumi Suenaga ,  Kenji Shibata ,  Kazutoshi Watanabe ,  Akira Nomoto

IPC: H01L41/187 ,  H01L41/08 ,  H01L41/316

CPC classification number: H01L41/0805 ,  H01L41/1873 ,  H01L41/316

Abstract: Disclosed are a piezoelectric thin film element and a piezoelectric thin film device which have improved piezoelectric properties and high performance and can be produced in improved yields. The piezoelectric thin film element (1) comprises: a substrate (10), and a piezoelectric thin film (40) which is arranged on the substrate (10), has at least one crystal structure represented by general formula (NaxKyLiz)NbO3 (0≦x≦1, 0≦y≦1, 0≦z≦0.2, x+y+z=1) and selected from the group consisting of pseudo-cubic crystal, a hexagonal crystal, and an orthorhombic crystal, and contains an inert gas element at a ratio of 80 ppm or less by mass.

Abstract translation: 公开了一种压电薄膜元件和压电薄膜器件，其具有改进的压电性能和高性能，并且可以以提高的产率制造。 压电薄膜元件（1）包括：基板（10）和布置在基板（10）上的压电薄膜（40），具有至少一个由通式（NaxKyLiz）NbO 3（0＆nlE）表示的晶体结构 ; x＆nlE; 1,0，nlE; y＆nlE; 1,0，nlE; z＆nlE; 0.2，x + y + z = 1），选自假立方晶体，六方晶体和正交晶体， 气体元素的比例为80ppm以下。

公开(公告)号：US08569294B2

公开(公告)日：2013-10-29

申请号：US12282396

申请日：2007-03-14

Applicant: Kenji Fukunaga ,  Toshiyuki Kohara ,  Kazutoshi Watanabe ,  Yoshihiro Usui ,  Fumiaki Uehara ,  Satoshi Yokoshima ,  Daiki Sakai ,  Shin-ichi Kusaka ,  Kazuki Nakayama

Inventor： Kenji Fukunaga ,  Toshiyuki Kohara ,  Kazutoshi Watanabe ,  Yoshihiro Usui ,  Fumiaki Uehara ,  Satoshi Yokoshima ,  Daiki Sakai ,  Shin-ichi Kusaka ,  Kazuki Nakayama

IPC: A61K31/535

CPC classification number: C07D413/14 ,  C07D401/04 ,  C07D401/14 ,  C07D403/14 ,  C07D409/14 ,  C07D453/06 ,  C07D493/04

Abstract: A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein R2 represents a hydrogen or the like; R3 represents methyl group or the like; R20 represents a halogen atom or the like; q represents an integer of 0 to 3; Z represent nitrogen atom, CH, or the like; R4 represents hydrogen or the like; R5 represents hydrogen or the like; R6 represents a substituted alkyloxy and the like; p represents an integer of 0 to 3; X represents bond, CH2, oxygen atom, NH, or the like; any one or more of R5 and R6, R5 and R4, R6 and R4, X and R5, X and R4, X and R6, and R6 and R6 may combine to each other to form a ring, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).

Abstract translation: 由式（I）表示的化合物或其光学活性异构体或其药学上可接受的盐：其中R2表示氢等; R3表示甲基等; R 20表示卤素原子等; q表示0〜3的整数， Z表示氮原子，CH等; R4表示氢等; R5表示氢等; R6表示取代的烷氧基等; p表示0〜3的整数， X表示键，CH2，氧原子，NH等; R 5和R 6，R 5和R 4，R 6和R 4，X和R 5，X和R 4，X和R 6以及R 6和R 6中的任何一个或多个可以彼此结合形成环，其用于预防和/ 或治疗由tau蛋白激酶1多动症如神经变性疾病（例如阿尔茨海默病）引起的疾病。

公开(公告)号：US08288383B2

公开(公告)日：2012-10-16

申请号：US12677161

申请日：2008-09-12

Applicant: Daiki Sakai ,  Kazutoshi Watanabe

Inventor： Daiki Sakai ,  Kazutoshi Watanabe

IPC: A61K31/535 ,  C07D413/14

CPC classification number: C07D413/14

Abstract: A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease).

Abstract translation: 由式（I）表示的化合物或其药学上可接受的盐：用于预防和/或治疗由tau蛋白激酶1的异常活性（例如神经变性疾病（例如阿尔茨海默病））引起的疾病。

公开(公告)号：US08214915B2

公开(公告)日：2012-07-03

申请号：US12455556

申请日：2009-06-03

Applicant: Masatsugu Shigeno ,  Kazutoshi Watanabe ,  Masato Iyoki ,  Naoya Watanabe

Inventor： Masatsugu Shigeno ,  Kazutoshi Watanabe ,  Masato Iyoki ,  Naoya Watanabe

IPC: G01Q20/00

CPC classification number: G01Q70/14 ,  G01G3/12 ,  G01G9/00 ,  G01Q10/045 ,  G01Q60/32

Abstract: Provided is a cantilever that is capable of bending and deforming in an active manner by itself. The cantilever includes: a lever portion having a proximal end that is supported by a main body part; and a resistor member that is formed in the cantilever and generates heat when a voltage is applied, to thereby deform the lever portion by thermal expansion due to the heat.

Abstract translation: 本发明提供一种能够以活跃的方式自身弯曲和变形的悬臂。 悬臂包括：杠杆部分，其具有由主体部分支撑的近端; 以及形成在悬臂中并在施加电压时产生热量的电阻器构件，从而通过由于热量的热膨胀而使杆部变形。

公开(公告)号：US08129377B2

公开(公告)日：2012-03-06

申请号：US11576062

申请日：2005-09-29

Applicant: Kazutoshi Watanabe ,  Kenji Fukunaga ,  Toshiyuki Kohara ,  Fumiaki Uehara ,  Shinsuke Hiki ,  Satoshi Yokoshima

Inventor： Kazutoshi Watanabe ,  Kenji Fukunaga ,  Toshiyuki Kohara ,  Fumiaki Uehara ,  Shinsuke Hiki ,  Satoshi Yokoshima

IPC: A61K31/535 ,  A61K31/505 ,  A01N43/54 ,  C07D413/00

CPC classification number: C07D401/04 ,  C07D401/14 ,  C07D409/14 ,  C07D413/14

Abstract: A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein R1 represents a C1-C12 alkyl; R2 represents a hydrogen atom or the like; R3 represents a halogen or the like; q represents an integer of 1 to 7; R4 represents a halogen or the like; p represents 0 or an integer of 1 to 5; R5 represents a C6-C10 aryl, a heterocycle or the like; and X represents oxygen, NH, or the like, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).

Abstract translation: 由式（I）表示的化合物，其光学活性异构体或其药学上可接受的盐：其中R1表示C1-C12烷基; R2表示氢原子等; R3表示卤素等; q表示1〜7的整数， R4表示卤素等; p表示0或1〜5的整数。 R5表示C6-C10芳基，杂环等; X代表氧，NH等，其用于预防和/或治疗由tau蛋白激酶1多动症如神经变性疾病（例如阿尔茨海默病）引起的疾病。

公开(公告)号：US08120059B2

公开(公告)日：2012-02-21

申请号：US12585109

申请日：2009-09-03

Applicant: Kazutoshi Watanabe ,  Takehiro Yoshida

Inventor： Kazutoshi Watanabe ,  Takehiro Yoshida

IPC: H01L29/02 ,  H01L21/311

CPC classification number: B24B9/065

Abstract: A nitride semiconductor substrate includes a front surface, a rear surface on an opposite side to the front surface, and a first edge portion including a chamfered edge on the front surface. A ratio of an average surface roughness of the front surface to an average surface roughness of the first edge portion is not more than 0.01.

Abstract translation: 氮化物半导体衬底包括前表面，与前表面相反侧的后表面，以及在前表面上包括倒角边缘的第一边缘部分。 前表面的平均表面粗糙度与第一边缘部分的平均表面粗糙度之比不大于0.01。

公开(公告)号：US07994315B2

公开(公告)日：2011-08-09

申请号：US11996205

申请日：2006-07-21

Applicant: Masahiro Okuyama ,  Fumiaki Uehara ,  Hiroshi Iwamura ,  Kazutoshi Watanabe

Inventor： Masahiro Okuyama ,  Fumiaki Uehara ,  Hiroshi Iwamura ,  Kazutoshi Watanabe

IPC: C07D265/30

CPC classification number: C07D265/30 ,  C07D265/32

Abstract: Production method of an optically active morpholine compound represented by the formula 10, or a compound represented by the formula 55, which includes the following steps: or wherein each symbol is as defined in the specification. An optically active 2-aryl-substituted morpholine compound and 3-oxo-3-(pyrimidin-4-yl)propionate, which are important as starting materials for synthesizing 2-(2-arylmorpholin-4-yl)-1-methyl-1H-[4,4′]bipyrimidinyl-6-one having a tau protein kinase 1 inhibitory activity and useful as a therapeutic drug for Alzheimer's disease and the like, can be produced in a high yield by an industrially advantageous method.

Abstract translation: 由式10表示的光学活性吗啉化合物的制备方法或由式55表示的化合物，其包括以下步骤：或其中每个符号如说明书中所定义。 光学活性的2-芳基取代的吗啉化合物和3-氧代-3-（嘧啶-4-基）丙酸酯，其作为合成2-（2-芳基吗啉-4-基）-1-甲基 - 可以通过工业上有利的方法以高产率制备具有tau蛋白激酶1抑制活性并且可用作阿尔茨海默氏病等的治疗药物的1H- [4,4']联嘧啶基-6-酮。

公开(公告)号：US07740703B2

公开(公告)日：2010-06-22

申请号：US10803087

申请日：2004-03-18

Applicant: Mitsuru Hasegawa ,  Akihiro Miyauchi ,  Kazutoshi Watanabe ,  Meguro Takeshi

Inventor： Mitsuru Hasegawa ,  Akihiro Miyauchi ,  Kazutoshi Watanabe ,  Meguro Takeshi

IPC: C23C16/46 ,  C23C16/458 ,  C23C16/48 ,  C23C16/52 ,  C23C16/06 ,  C23C16/22

CPC classification number: C23C16/46 ,  C30B25/10 ,  C30B25/16

Abstract: A semiconductor film formation device has: a reaction vessel that includes a gas flow path to allow source gas to pass through and a substrate mount site provided in the gas flow path to mount a substrate; a temperature control means that is disposed opposite to the substrate mount site and close to the reaction vessel to control the internal temperature of the reaction vessel; and a thermal conductivity adjusting member that is disposed between the reaction vessel and the temperature control means. The thermal conductivity adjusting member has a section with a thermal conductivity different from the other section along the gas flow path.

Abstract translation: 半导体膜形成装置具有：包括允许源气体通过的气体流路和设置在气体流路中的基板安装位置以安装基板的反应容器; 温度控制装置，其与基板安装位置相对设置并且靠近反应容器以控制反应容器的内部温度; 以及设置在反应容器和温度控制装置之间的导热性调节构件。 导热性调节构件具有沿着气体流动路径具有不同于另一部分的热导率的截面。

公开(公告)号：US07442925B2

公开(公告)日：2008-10-28

申请号：US11370006

申请日：2006-03-04

Applicant: Masatoshi Yasutake ,  Takuya Nakaue ,  Kazutoshi Watanabe ,  Osamu Takaoka ,  Atsushi Uemoto ,  Naoya Watanabe ,  Yoshiteru Shikakura

Inventor： Masatoshi Yasutake ,  Takuya Nakaue ,  Kazutoshi Watanabe ,  Osamu Takaoka ,  Atsushi Uemoto ,  Naoya Watanabe ,  Yoshiteru Shikakura

IPC: G01N13/16

CPC classification number: G01N23/225 ,  G01Q60/34

Abstract: The present invention provides a working method using a scanning probe which can enhance a working speed and prolong a lifetime of the probe. The present invention provides the working method using a scanning probe which works a sample by performing the relative scanning of a probe supported on a cantilever on the sample at a predetermined scanning speed. The working method can work the object to be worked while forcibly and relatively vibrating the probe in the direction orthogonal to or parallel to a working surface of the sample at low frequency of 100 to 1000 Hz.

Abstract translation: 本发明提供一种使用扫描探针的工作方法，其可以提高工作速度并延长探针的寿命。 本发明提供了使用扫描探针的工作方法，该扫描探针通过以预定扫描速度执行支撑在样品上的悬臂上的探针的相对扫描来对样品进行工作。 该工作方法可以在100至1000Hz的低频下，以与样品的工作表面正交或平行的方向强制地相对振动探针，从而对被加工物进行加工。