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公开(公告)号：US20050169798A1
公开(公告)日：2005-08-04
申请号：US11090550
申请日：2005-03-25
IPC分类号： G01N27/12 , G01N27/414 , G01N31/22
CPC分类号： B82Y15/00 , G01N27/129 , Y10S977/734
摘要： Nanostructure sensing devices for detecting an analyte are described. The devices include nanostructures connected to conductive elements, all on a substrate. Contact regions adjacent to points of contact between the nanostructures and the conductive elements are given special treatment. The proportion of nanostructure surface area within contact regions can be maximized to effect sensing at very low analyte concentrations. The contact regions can be passivated in an effort to prevent interaction between the environment and the contact regions for sensing at higher analyte concentrations and for reducing cross-sensing. Both contact regions and at least some portion of the nanostructures can be covered with a material that is at least partially permeable to the analyte of interest and impermeable to some other species to tune selectivity and sensitivity of the nanostructure sensing device.
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公开(公告)号：US20070114573A1
公开(公告)日：2007-05-24
申请号：US10655529
申请日：2003-09-04
申请人： Tzong-Ru Han , Alexander Star , Philip Collins , Jean-Christophe Gabriel , George Gruner , Keith Bradley
发明人： Tzong-Ru Han , Alexander Star , Philip Collins , Jean-Christophe Gabriel , George Gruner , Keith Bradley
IPC分类号： H01L29/768
CPC分类号： G01N25/20
摘要： A nanostructure sensing device includes a substrate, a nanotube disposed over the substrate, and at least two conductive elements electrically connected to the nanotube. A electric current on the order of about 10 μA, or greater, is passed through the conductive elements and the nanotube. As a result, the nanotube heats up relative to the substrate. In the alternative, some other method may be used to heat the nanotube. When operated as a sensor with a heated nanotube, the sensor's response and/or recovery time may be markedly improved.
摘要翻译： 纳米结构感测装置包括衬底，设置在衬底上的纳米管以及电连接到纳米管的至少两个导电元件。 大约10μA或更大的电流通过导电元件和纳米管。 结果，纳米管相对于基底加热。 在替代方案中，可以使用一些其它方法来加热纳米管。 当作为具有加热的纳米管的传感器操作时，可以显着改善传感器的响应和/或恢复时间。
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公开(公告)号：US20060228723A1
公开(公告)日：2006-10-12
申请号：US11259414
申请日：2005-10-25
申请人： Keith Bradley , Jean-Christophe Gabriel , George Gruner , Alexander Star , Eugene Tu , Christian Valcke
发明人： Keith Bradley , Jean-Christophe Gabriel , George Gruner , Alexander Star , Eugene Tu , Christian Valcke
CPC分类号： B82Y30/00 , B01L3/50857 , B01L2300/0636 , B01L2300/0663 , B01L2300/0819 , B01L2300/0851 , B01L2300/0893 , B01L2300/0896 , B01L2300/16 , B82Y10/00 , G01N33/5438 , G01N33/551 , G01N33/566 , G01N33/582
摘要： A nanoelectronic device is combined with a cellular membrane component to provide a sensor for biomolecules or to provide information about the structure of the membrane. The nanoelectronic device may comprise a network of randomly-oriented nanotubes, or other nanostructure, arranged on a substrate with adjacent electrodes so as to operate as a field-effect transistor sensor or as a capacitive sensor. A cellular membrane is disposed over the nanostructure element.
摘要翻译： 纳米电子器件与细胞膜组件组合以提供用于生物分子的传感器或提供关于膜结构的信息。 纳米电子器件可以包括布置在具有相邻电极的衬底上的随机取向的纳米管或其他纳米结构的网络，以便作为场效应晶体管传感器或电容式传感器工作。 细胞膜设置在纳米结构元件上。
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4.发明申请公开(公告)号：US20060263255A1
公开(公告)日：2006-11-23
申请号：US11354561
申请日：2006-02-14
申请人： Tzong-Ru Han , Alexander Star , Jean-Christophe Gabriel , Sergei Skarupo , John Passmore , Philip Collins , Keith Bradley , Darin Olson
发明人： Tzong-Ru Han , Alexander Star , Jean-Christophe Gabriel , Sergei Skarupo , John Passmore , Philip Collins , Keith Bradley , Darin Olson
IPC分类号： G01N33/00
CPC分类号： B82Y15/00 , B82Y10/00 , B82Y30/00 , G01N27/4141 , G01N27/4146 , G01N33/005
摘要： A new sensing technology for chemical/biomolecular sensors is provided. One such sensor detects molecular hydrogen (H2) using nanoelectronic components. A tiny, low-cost nanosensor chip can offer: (i) performance that matches or exceeds that of existing technology, (ii) plug-and-play simplicity with both digital and analog control systems, and (ii) the small size and low power consumption needed for wireless integration.
摘要翻译： 提供了一种用于化学/生物分子传感器的新型传感技术。 一种这样的传感器使用纳米电子部件检测分子氢（H 2 N 2）。 一个小型，低成本的纳米传感器芯片可以提供：（i）匹配或超过现有技术的性能，（ii）数字和模拟控制系统的即插即用简单性，以及（ii）小尺寸和低 无线集成所需的功耗。
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公开(公告)号：US20070178477A1
公开(公告)日：2007-08-02
申请号：US11212026
申请日：2005-08-24
CPC分类号： C12Q1/6825 , G01N27/4145 , G01N27/4146 , C12Q2565/631 , C12Q2565/107
摘要： A nanotube device is configured as an electronic sensor for a target DNA sequence. A film of nanotubes is deposited over electrodes on a substrate. A solution of single-strand DNA is prepared so as to be complementary to a target DNA sequence. The DNA solution is deposited over the electrodes, dried, and removed from the substrate except in a region between the electrodes. The resulting structure includes strands of the desired DNA sequence in direct contact with nanotubes between opposing electrodes, to form a sensor that is electrically responsive to the presence of target DNA strands. Alternative assay embodiments are described which employ linker groups to attach ssDNA probes to the nanotube sensor device.
摘要翻译： 纳米管装置配置为目标DNA序列的电子传感器。 将纳米管膜沉积在基板上的电极上。 制备单链DNA的溶液以与靶DNA序列互补。 将DNA溶液沉积在电极上，干燥，除去电极之外的区域。 所得结构包括与相对电极之间的纳米管直接接触的所需DNA序列的链，以形成对目标DNA链的存在电响应的传感器。 描述了使用连接体将ssDNA探针连接到纳米管传感器装置的替代试验实施方案。
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公开(公告)号：US20050279987A1
公开(公告)日：2005-12-22
申请号：US10656898
申请日：2003-09-05
IPC分类号： G01N33/543 , H01L29/06 , H01L51/00 , H01L51/05
CPC分类号： G01N33/5438 , B82Y10/00 , H01L51/0048 , H01L51/0052 , H01L51/0512
摘要： A nanostructure device is made up of a nanostructure, such as a single-walled carbon nanotube, spanning two electrical conductors, mounted on a substrate. A passivation layer may cover a portion of the conductors and the nanostructure. A thin polymer layer is deposited over an exposed portion of the nanotube. In this configuration, the device may perform like an n-type field effect transistor. The polymer material may be selected for interactivity with a particular chemical species or compound. The device may therefore be used as a resistive sensor that responds to the particular species or compound by exhibiting a change in resistivity.
摘要翻译： 纳米结构器件由安装在衬底上的跨越两个电导体的纳米结构例如单壁碳纳米管组成。 钝化层可以覆盖导体和纳米结构的一部分。 在纳米管的暴露部分上沉积薄聚合物层。 在这种配置中，器件可以像n型场效应晶体管那样执行。 可以选择聚合物材料与特定化学物质或化合物的相互作用。 因此，该装置可以用作通过显示电阻率变化来响应特定种类或化合物的电阻式传感器。
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公开(公告)号：US20050129573A1
公开(公告)日：2005-06-16
申请号：US10940324
申请日：2004-09-13
IPC分类号： G01N27/00 , G01N27/414 , G01N33/00
CPC分类号： G01N27/4146 , B82Y10/00 , B82Y15/00 , G01N27/4141 , G01N33/004 , Y10T436/204998
摘要： An electronic system and method for detecting carbon dioxide is provided, using a nanostructure sensing device (CO2 sensor). The CO2 sensor is made up of a substrate and a nanostructure disposed over the substrate. The nanostructure may comprise a carbon nanotube, or a network of nanotubes. Two conductive elements are disposed over the substrate and electrically connected to the nanotube. A gate electrode may be positioned opposite the nanostructure. A functionalization material reactive with carbon dioxide is disposed on CO2 sensor, and in particular, on the nanotube. The CO2 sensor may be connected to an electrical circuit, which will respond to changes in CO2 concentration in the ambient sensor environment.
摘要翻译： 提供了一种用于检测二氧化碳的电子系统和方法，使用纳米结构感测装置（CO 2传感器）。 CO 2传感器由衬底和设置在衬底上的纳米结构构成。 纳米结构可以包括碳纳米管或纳米管网络。 两个导电元件设置在衬底上并电连接到纳米管。 栅电极可以位于与纳米结构相对的位置。 与二氧化碳反应的官能化材料设置在CO 2传感器上，特别是在纳米管上。 CO 2传感器可以连接到电路，其将响应环境传感器环境中CO 2 2浓度的变化。
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公开(公告)号：US20050157445A1
公开(公告)日：2005-07-21
申请号：US10945803
申请日：2004-09-20
申请人： Keith Bradley , Alona Davis , Jean-Christophe Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
发明人： Keith Bradley , Alona Davis , Jean-Christophe Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
IPC分类号： G01N27/00 , G01N27/414 , G01N33/00 , H02H1/00
CPC分类号： B82Y30/00 , G01N27/4146 , G01N33/005 , Y10S977/72
摘要： A nanoelectronic device includes a nanostructure, such as a nanotube or network of nanotubes, disposed on a substrate. Nanoparticles are disposed on or adjacent to the nanostructure so as to operatively effect the electrical properties of the nanostructure. The nanoparticles may be composed of metals, metal oxides, or salts, and nanoparticles composed of different materials may be present. The amount of nanoparticles may be controlled to preserve semiconductive properties of the nanostructure, and the substrate immediately adjacent to the nanostructure may remain substantially free of nanoparticles. A method for fabricating the device includes electrodeposition of the nanoparticles using one or more solutions of dissolved ions while providing an electric current to the nanostructures but not to the surrounding substrate.
摘要翻译： 纳米电子器件包括设置在衬底上的纳米结构，例如纳米管或纳米管网络。 将纳米颗粒设置在纳米结构上或与纳米结构相邻，以便有效地影响纳米结构的电性能。 纳米颗粒可以由金属，金属氧化物或盐组成，并且可以存在由不同材料组成的纳米颗粒。 可以控制纳米颗粒的量以保持纳米结构的半导体性质，并且紧邻纳米结构的衬底可以基本上不含纳米颗粒。 制造该器件的方法包括使用一种或多种溶解离子的溶液电沉积纳米颗粒，同时向纳米结构提供电流，而不向周围的衬底提供电流。
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公开(公告)号：US06894359B2
公开(公告)日：2005-05-17
申请号：US10280265
申请日：2002-10-26
申请人： Keith Bradley , Philip G. Collins , Jean-Christophe P. Gabriel , George Gruner , Alexander Star
发明人： Keith Bradley , Philip G. Collins , Jean-Christophe P. Gabriel , George Gruner , Alexander Star
IPC分类号： G01N27/12 , G01N27/414 , H01L27/14 , H01L29/82 , H01L29/84
CPC分类号： B82Y15/00 , G01N27/129 , Y10S977/734
摘要： Nanostructure sensing devices for detecting an analyte are described. The devices include nanostructures connected to conductive elements, all on a substrate. Contact regions adjacent to points of contact between the nanostructures and the conductive elements are given special treatment. The proportion of nanostructure surface area within contact regions can be maximized to effect sensing at very low analyte concentrations. The contact regions can be passivated in an effort to prevent interaction between the environment and the contact regions for sensing at higher analyte concentrations and for reducing cross-sensing. Both contact regions and at least some portion of the nanostructures can be covered with a material that is at least partially permeable to the analyte of interest and impermeable to some other species to tune selectivity and sensitivity of the nanostructure sensing device.
摘要翻译： 描述了用于检测分析物的纳米结构感测装置。 这些器件包括连接到导电元件的纳米结构，全部在衬底上。 给予与纳米结构和导电元件之间的接触点相邻的接触区域的特殊处理。 可以使接触区域内的纳米结构表面积的比例最大化，以在非常低的分析物浓度下进行感测。 可以钝化接触区域，以防止环境和接触区域之间的相互作用，以便在较高分析物浓度下进行感测并减少交叉感测。 两个接触区域和纳米结构的至少一部分可以被对感兴趣的分析物至少部分可渗透的材料覆盖，并且对于一些其它物质是不可渗透的，以调节纳米结构感测装置的选择性和灵敏度。
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公开(公告)号：US20090165533A1
公开(公告)日：2009-07-02
申请号：US12245638
申请日：2008-10-03
申请人： Tzong-Ru Han , Alexander Star , Philip G. Collins , Jean-Christophe P. Gabriel , George Gruner , Keith Bradley
发明人： Tzong-Ru Han , Alexander Star , Philip G. Collins , Jean-Christophe P. Gabriel , George Gruner , Keith Bradley
IPC分类号： G01N7/00
CPC分类号： G01N25/20
摘要： A nanostructure sensing device includes a substrate, a nanotube disposed over the substrate, and at least two conductive elements electrically connected to the nanotube. A electric current on the order of about 10 μA, or greater, is passed through the conductive elements and the nanotube. As a result, the nanotube heats up relative to the substrate. In the alternative, some other method may be used to heat the nanotube. When operated as a sensor with a heated nanotube, the sensor's response and/or recovery time may be markedly improved.
摘要翻译： 纳米结构感测装置包括衬底，设置在衬底上的纳米管以及电连接到纳米管的至少两个导电元件。 大约10μA或更大的电流通过导电元件和纳米管。 结果，纳米管相对于基底加热。 在替代方案中，可以使用一些其它方法来加热纳米管。 当作为具有加热的纳米管的传感器操作时，可以显着改善传感器的响应和/或恢复时间。
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