Raman spectrometer
    1.
    发明授权
    Raman spectrometer 有权
    拉曼光谱仪

    公开(公告)号:US07403281B2

    公开(公告)日:2008-07-22

    申请号:US10859372

    申请日:2004-06-01

    IPC分类号: G01J3/44

    摘要: A system, method and apparatus for taking a Raman spectrum of a sample is disclosed. In one embodiment, for example, an integrated Raman spectrometer is provided. In another embodiment, a portable Raman spectrometer is provided. In another embodiment, a Raman spectrometer is provided comprising a collimated beam tube for transmitting excitation radiation to an external optical system, such as a microscope, a telescope or a camera lens. In another embodiment, a method for correcting a Raman spectrum for background interference is provided. In yet another embodiment, a method for rejecting fluorescence in a Raman spectrometer is provided. A chemical reactor comprising a built-in Raman detector for monitoring a chemical reaction in a reaction chamber of the reactor is also provided.

    摘要翻译: 公开了一种用于获取样品的拉曼光谱的系统,方法和装置。 在一个实施例中,例如,提供了一种集成的拉曼光谱仪。 在另一个实施例中,提供了便携式拉曼光谱仪。 在另一个实施例中,提供拉曼光谱仪,其包括用于将激发辐射传输到诸如显微镜,望远镜或相机透镜的外部光学系统的准直束管。 在另一实施例中,提供了用于校正背景干扰的拉曼光谱的方法。 在另一个实施方案中,提供了一种用于在拉曼光谱仪中排除荧光的方法。 还提供了一种包括用于监测反应器的反应室中的化学反应的内置拉曼检测器的化学反应器。

    CYANIDE AND RELATED SPECIES DETECTION WITH METAL SURFACES
    2.
    发明申请
    CYANIDE AND RELATED SPECIES DETECTION WITH METAL SURFACES 有权
    CYANIDE和相关物种用金属表面检测

    公开(公告)号:US20100291701A1

    公开(公告)日:2010-11-18

    申请号:US12843997

    申请日:2010-07-27

    IPC分类号: B01L3/00

    CPC分类号: G01N21/658

    摘要: An assay method and kit for detecting a chemical. The method and kit utilize a metal surface capable of surface enhanced Raman Scattering. The metal surface may be provided in the form of one or more nanoparticles, to increase the surface enhanced Raman Scattering capability of the metal surface. The nanoparticles may be treated with one or more additives to further enhance or maintain the surface enhanced Raman Scattering capability of the nanoparticles.

    摘要翻译: 用于检测化学物质的测定方法和试剂盒。 该方法和试剂盒利用能够进行表面增强拉曼散射的金属表面。 金属表面可以以一种或多种纳米颗粒的形式提供,以增加金属表面的表面增强的拉曼散射能力。 可以用一种或多种添加剂处理纳米颗粒以进一步增强或维持纳米颗粒的表面增强的拉曼散射能力。

    OPTICAL BEAM SPECTROMETER
    4.
    发明申请
    OPTICAL BEAM SPECTROMETER 有权
    光束光谱仪

    公开(公告)号:US20090135417A1

    公开(公告)日:2009-05-28

    申请号:US12268419

    申请日:2008-11-10

    IPC分类号: G01J3/44

    摘要: A spectroscopic system is described that provides at least one of focus of an excitation beam onto a sample, automatic focus of an optical system of the spectroscopic system for collecting a spectroscopic signal, and/or averaging of excitation intensity over a surface area of the sample.

    摘要翻译: 描述了一种分光系统,其将激发光束的焦点中的至少一个提供到样本上,用于收集分光信号的光谱系统的光学系统的自动聚焦和/或样品的表面积上的激发强度的平均值 。

    Method and apparatus for detection of a controlled substance
    6.
    发明授权
    Method and apparatus for detection of a controlled substance 有权
    用于检测受控物质的方法和装置

    公开(公告)号:US06558956B1

    公开(公告)日:2003-05-06

    申请号:US09446168

    申请日:1999-12-17

    IPC分类号: G01N2165

    摘要: Techniques and devices for detecting and analyzing controlled substances and the like are discussed including highly reactive sensor molecules which are coated on a spectroscopic sample surface (4) and which may chemically react with a given analyte to form a covalently bonded adduct with spectral characteristics unique to the new adduct. The techniques provide the basis of a detection system with high sensitivity and high specificity in which the surface can even be washed to remove interfering or nonreactive compounds. The sensor molecules which comprise the coating (8) may have three major components: a central molecular scaffold (“CMS”), a “tether” terminated by a surface attachment group “SAG,” and a reactive functional group “RFG” which may be highly reactive towards certain classes of molecules. One or more modifiers or modifier groups “Z” which may serve to increase or decrease the reactivity of the RFG towards target analytes, or to modify the spectral characteristics of the adduct may also be included. Some sensor molecules include diazonium compounds, activated acyls, and nitrosos.

    摘要翻译: 讨论了用于检测和分析受控物质等的技术和装置,其包括涂覆在光谱样品表面(4)上的高反应性传感器分子,并且其可以与给定的分析物发生化学反应,以形成共价键合的加合物, 新加入。 该技术提供了具有高灵敏度和高特异性的检测系统的基础,其中表面甚至可以被洗涤以除去干扰或非反应性化合物。 包含涂层(8)的传感器分子可以具有三个主要组分:中心分子支架(“CMS”),由表面附着基团“SAG”终止的“连接臂”和可能的表面附着基团“RFG”的反应性官能团“RFG” 对某些类别的分子具有高反应性。 还可以包括一种或多种改性剂或修饰基团“Z”,其可用于增加或降低RFG对靶分析物的反应性,或修饰加合物的光谱特征。 一些传感器分子包括重氮化合物,活化的酰基和亚硝基。

    Cyanide and related species detection with metal surfaces
    7.
    发明授权
    Cyanide and related species detection with metal surfaces 有权
    氰化物和金属表面的相关物种检测

    公开(公告)号:US07776610B2

    公开(公告)日:2010-08-17

    申请号:US10840090

    申请日:2004-05-06

    IPC分类号: G01N21/62 G01N21/00

    CPC分类号: G01N21/658

    摘要: An assay method and kit for detecting a chemical. The method and kit utilize a metal surface capable of surface enhanced Raman Scattering. The metal surface may be provided in the form of one or more nanoparticles, to increase the surface enhanced Raman Scattering capability of the metal surface. The nanoparticles may be treated with one or more additives to further enhance or maintain the surface enhanced Raman Scattering capability of the nanoparticles.

    摘要翻译: 用于检测化学物质的测定方法和试剂盒。 该方法和试剂盒利用能够进行表面增强拉曼散射的金属表面。 金属表面可以以一种或多种纳米颗粒的形式提供,以增加金属表面的表面增强的拉曼散射能力。 可以用一种或多种添加剂处理纳米颗粒以进一步增强或维持纳米颗粒的表面增强的拉曼散射能力。