TAPE HEATER AND METHOD FOR MANUFACTURING THE SAME
    1.
    发明申请
    TAPE HEATER AND METHOD FOR MANUFACTURING THE SAME 审中-公开
    胶带加热器及其制造方法

    公开(公告)号:US20090242548A1

    公开(公告)日:2009-10-01

    申请号:US12410642

    申请日:2009-03-25

    IPC分类号: H05B3/34 D04B1/22

    摘要: The present invention relates to a tape heater including: at least one flexible fabric base formed from a heat-resistant thread, the at least one flexible fabric base including a first fabric base part and a second fabric base part; and a heater member, in which the heater member is interposed between the first fabric base part and the second fabric base pan. Since the heater member is interposed between the fabric base(s), the tape heater of the present invention exhibits superior flexibility and stretchability and is superior in easily being wrapped around a pipe, as well as reliably protecting the heater member. Further, tape heaters can be continually manufactured, so long as weaving or knitting of the fabric base(s) is caused to proceed while the heater member is interposed between the fabric base(s), to thus join the fabric base(s). Hence, enhancement of production efficiency and prevention of an increase in production cost can be attained.

    摘要翻译: 带加热器技术领域本发明涉及一种带式加热器,包括:由耐热螺纹形成的至少一个柔性织物基底,所述至少一个柔性织物基底包括第一织物基部和第二织物基部; 以及加热器构件,其中加热器构件插入在第一织物基部和第二织物底盘之间。 由于加热件插在织物基底之间,所以本发明的带状加热器显示出优异的柔韧性和拉伸性,并且易于缠绕在管子上而且可靠地保护加热器部件。 此外,只要在加热器构件插入织物基底之间进行织物基底的织造或编织,从而连接织物基底,就可以连续地制造带加热器。 因此,可以提高生产效率并防止生产成本的增加。

    Methods for inducing cell death in pluripotent stem cells and differentiated cells other than cardiac myocytes
    5.
    发明授权
    Methods for inducing cell death in pluripotent stem cells and differentiated cells other than cardiac myocytes 有权
    在多能干细胞和心肌细胞以外的分化细胞中诱导细胞死亡的方法

    公开(公告)号:US08735152B2

    公开(公告)日:2014-05-27

    申请号:US13260224

    申请日:2010-03-29

    IPC分类号: C12N5/00 C12N5/02

    摘要: The present invention has as its object developing a method that does not involve genomic modification and which yet is capable of inducing cell death in pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, as well as in differentiated cells other than cardiomyocytes derived from pluripotent stem cells, but not in cardiomyocytes. It has been revealed that by establishing a method capable of inducing cell death in cells other than cardiomyocytes in a very efficient manner by adding a substance having no recognized inherent toxicity or cell death inducing action to the culture conditions for pluripotent stem cells and non-cardiomyocytes, the stated problem can be solved without relying upon genomic modification.

    摘要翻译: 本发明的目的是开发一种不涉及基因组修饰并且能够在多能干细胞如胚胎干细胞和诱导的多能干细胞以及除了心肌细胞以外的分化细胞中诱导细胞死亡的方法 来自多能干细胞,但不在心肌细胞中。 已经揭示出,通过向多能干细胞和非心肌细胞的培养条件中加入不具有公认的固有毒性或细胞死亡诱导作用的物质,通过建立能够以非常有效的方式在除心肌细胞之外的细胞中诱导细胞死亡的方法 所述问题可以解决而不依赖于基因组修饰。

    THERAPEUTIC AGENTS FOR MUSCULAR DYSTROPHY
    6.
    发明申请
    THERAPEUTIC AGENTS FOR MUSCULAR DYSTROPHY 审中-公开
    用于肌肉晶状体的治疗剂

    公开(公告)号:US20130302272A1

    公开(公告)日:2013-11-14

    申请号:US13988255

    申请日:2011-11-17

    IPC分类号: A61K38/19

    CPC分类号: A61K38/193

    摘要: The present invention provides therapeutic agents for diseases associated with skeletal muscle degeneration comprising a granulocyte colony-stimulating factor (G-CSF) as an active ingredient. The therapeutic agents of the present invention are especially effective as therapeutic agents for muscular dystrophy.

    摘要翻译: 本发明提供与骨骼肌变性相关的疾病的治疗剂,其包含粒细胞集落刺激因子(G-CSF)作为活性成分。 本发明的治疗剂作为肌营养不良症的治疗剂是特别有效的。

    Methods of recruiting fibroblasts by administering G-CSF
    10.
    发明授权
    Methods of recruiting fibroblasts by administering G-CSF 有权
    通过给予G-CSF募集成纤维细胞的方法

    公开(公告)号:US07531510B2

    公开(公告)日:2009-05-12

    申请号:US10577241

    申请日:2004-10-27

    IPC分类号: A61K38/00 A61K45/00

    CPC分类号: A61K38/193

    摘要: The object of the present invention is to achieve simple recruitment of fibroblasts into wounded tissues and engraftment of the fibroblasts in the wounded tissues, thereby healing the wounds without requiring fibroblast transplantation. Upon G-CSF administration, fibroblasts migrate into myocardial infarct lesions and prevent a reduction in cardiac function, thus alleviating cardiac remodeling.

    摘要翻译: 本发明的目的是实现将伤口组织中的成纤维细胞简单地募集到受伤组织中的成纤维细胞,从而使伤口愈合而不需要成纤维细胞移植。 在G-CSF施用后,成纤维细胞迁移到心肌梗塞病变中并防止心脏功能的降低,从而减轻心脏重塑。