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21 条记录 (耗时 0.033 秒)

    Method of judging leukemia, pre-leukemia or aleukemic malignant blood disease and diagnostic therefor
    2.
    发明授权
    Method of judging leukemia, pre-leukemia or aleukemic malignant blood disease and diagnostic therefor 失效
    判断白血病，白血病前或白血病恶性血液病的诊断方法

    公开(公告)号：US07479371B2

    公开(公告)日：2009-01-20

    申请号：US10510627

    申请日：2003-04-09

    申请人： Kiyoshi Ando ,  Tomomitsu Hotta ,  Chie Ito ,  Hidenao Sato ,  Akiko Furuya ,  Kenya Shitara ,  Seiji Sugimoto ,  Hiroaki Kohno

    发明人： Kiyoshi Ando ,  Tomomitsu Hotta ,  Chie Ito ,  Hidenao Sato ,  Akiko Furuya ,  Kenya Shitara ,  Seiji Sugimoto ,  Hiroaki Kohno

    IPC分类号： G01N33/53 ,  C07K16/00

    CPC分类号： C07K16/22 ,  G01N33/57426 ,  G01N2333/475

    摘要： The present invention relates to a method for diagnosing leukemia, pre-leukemia or aleukemic malignant blood diseases, a method of discriminating leukemia from pre-leukemia or aleukemic malignant blood diseases, a method of discriminating aplastic anemia from myelodysplastic syndrome, a method of diagnosing delayed engraftment of the hematopoietic stem cells after transplantation of the hematopoietic stem cells, and a method of diagnosing the graft versus host disease, each of said methods comprising quantifying stem cell growth factor (SCGF). The present invention also makes it possible to provide an agent for diagnosing leukemia, pre-leukemia or aleukemic malignant blood diseases and an agent for diagnosing delayed engraftment of the hematopoietic stem cells after transplantation of the hematopoietic stem cells or an agent for diagnosing graft versus host disease (GVHD), each containing as an active ingredient an antibody reacting with stem cell growth factor (SCGF).

    摘要翻译： 本发明涉及白血病，白血病前或白血病恶性血液病诊断方法，白血病与白血病前白血病恶性血液疾病的鉴别方法，再生障碍性贫血与骨髓增生异常综合征的鉴别方法，延迟诊断方法 造血干细胞移植后造血干细胞的移植，以及诊断移植物抗宿主病的方法，每种方法包括量化干细胞生长因子（SCGF）。 本发明还可以提供用于诊断白血病，白血病前或白血病恶性血液病的药剂和用于诊断造血干细胞移植后的造血干细胞的延迟植入或用于诊断移植物与宿主的试剂的试剂 疾病（GVHD），各自含有与干细胞生长因子（SCGF）反应的抗体作为活性成分。

    Intervertebral Disc Nucleus Pulposus Stem Cell/Progenitor Cell, The Cultivation Method And Intended Use Thereof
    9.
    发明申请
    Intervertebral Disc Nucleus Pulposus Stem Cell/Progenitor Cell, The Cultivation Method And Intended Use Thereof 审中-公开
    椎间盘髓核干细胞/祖细胞，培养方法及其用途

    公开(公告)号：US20130078222A1

    公开(公告)日：2013-03-28

    申请号：US13637470

    申请日：2011-03-29

    申请人： Daisuke Sakai ,  Joji Mochida ,  Kiyoshi Ando ,  Yoshihiko Nakamura

    发明人： Daisuke Sakai ,  Joji Mochida ,  Kiyoshi Ando ,  Yoshihiko Nakamura

    IPC分类号： C12N5/071

    CPC分类号： C12N5/0654 ,  A61K35/12 ,  C12N5/0655 ,  C12N5/0668 ,  C12N2501/17 ,  C12N2502/1394 ,  C12N2502/99

    摘要： Provided are intervertebral disk nucleus pulposus stem cells or progenitor cells that may be used for treatment of intervertebral disk disorders. An intervertebral disk nucleus pulposus cell is characterized by being isolated from the intervertebral disk nucleus pulposus of a vertebrate and is positive for at least one surface marker from among Tie2 and GD2. That is, the intervertebral disk nucleus pulposus stem cell is characterized by being at least Tie2-positive for the surface marker and) possesses a self-renewal ability as well as multipotency capable of differentiating into adipocytes, osteocytes, chondrocytes and neurons. Also provided is an intervertebral disk nucleus pulposus progenitor cell characterized by being at least Tie2-negative and GD2-positive for the surface marker and capable of differentiating into any of adipocytes, osteocytes, chondrocytes and neurons.

    摘要翻译： 提供可用于治疗椎间盘疾病的椎间盘髓核干细胞或祖细胞。 椎间盘髓核细胞的特征在于从脊椎动物的椎间盘髓核中分离，并且对于Tie2和GD2中的至少一个表面标记是阳性的。 也就是说，椎间盘髓核干细胞的特征在于对于表面标志物至少为Tie2阳性，并且具有能够分化成脂肪细胞，骨细胞，软骨细胞和神经元的自我更新能力以及多能性。 还提供了一种椎间盘髓核祖细胞，其特征在于对于表面标记至少具有Tie2阴性和GD2阳性，并且能够分化成任何脂肪细胞，骨细胞，软骨细胞和神经元。

    Hydrophilic film and process for producing the same
    10.
    发明授权
    Hydrophilic film and process for producing the same 失效
    亲水膜及其制造方法

    公开(公告)号：US06214382B1

    公开(公告)日：2001-04-10

    申请号：US08836049

    申请日：1997-12-23

    申请人： Tamiyuki Eguchi ,  Kiyoshi Ando ,  Yasuo Shimizu

    发明人： Tamiyuki Eguchi ,  Kiyoshi Ando ,  Yasuo Shimizu

    IPC分类号： A61K914

    CPC分类号： B01D67/0088

    摘要： This invention provides a hydrophilic membrane wherein a hydrophilic cellulose derivative of a number average molecular weight of 2000˜8000 is adsorbed irreversibly to a hydrophobic membrane of an aromatic polymer. Since an amount of leaching substances is extremely small, the membrane can be used suitably in such fields as medical applications, electronics, etc. where even a quite small quantity of leaching substances from the membranes is limited especially small.

    摘要翻译： 本发明提供一种亲水性膜，其中数均分子量为2000〜8000的亲水性纤维素衍生物不可逆地吸附在芳香族聚合物的疏水性膜上。由于浸出物质的量极少，因此可以适当地使用 诸如医疗应用，电子等领域，甚至来自膜的相当少量的浸出物质被限制得特别小。