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公开(公告)号：US09283099B2
公开(公告)日：2016-03-15
申请号：US10927601
申请日：2004-08-25
CPC分类号： A61F2/958 , A61F2002/30062 , A61F2002/30448 , A61F2002/9522 , A61F2002/9583 , A61F2210/0004 , A61F2220/005
摘要： Medical assemblies with a releasable connection and methods of constructing such medical assemblies are disclosed. The medical assemblies generally comprise a stent, a catheter assembly having catheter body a balloon, and a releasable connection between the stent and the catheter assembly that releases the stent from the catheter assembly in response to enlargement of the balloon or when the balloon has been enlarged to an expanded configuration.
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2.发明授权Stent-catheter assembly with a releasable connection for stent retention 有权支架 - 导管组件，具有用于支架保持的可释放连接公开(公告)号：US08470014B2
公开(公告)日：2013-06-25
申请号：US11893316
申请日：2007-08-14
申请人： David C. Gale , Klaus Kleine , Anthony Abbate , Svava M. Atladottir , Bin Huang
发明人： David C. Gale , Klaus Kleine , Anthony Abbate , Svava M. Atladottir , Bin Huang
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2002/30062 , A61F2002/30448 , A61F2002/9522 , A61F2002/9583 , A61F2210/0004 , A61F2220/005
摘要： Medical assemblies with a releasable connection and methods of constructing such medical assemblies are disclosed. The medical assemblies generally comprise a stent, a catheter assembly having catheter body a balloon, and a releasable connection between the stent and the catheter assembly that releases the stent from the catheter assembly in response to enlargement of the balloon or when the balloon has been enlarged to an expanded configuration.
摘要翻译： 公开了具有可释放连接的医疗组件和构造这种医疗组件的方法。 医疗组件通常包括支架，具有导管主体的气囊的导管组件，以及支架和导管组件之间的可释放连接，其响应于气囊的扩大或者当球囊已经扩大时从导管组件释放支架 扩展配置。
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公开(公告)号：US07971333B2
公开(公告)日：2011-07-05
申请号：US11443947
申请日：2006-05-30
申请人： David C. Gale , Bin Huang , Anthony J. Abbate , Timothy A. Limon , Klaus Kleine
发明人： David C. Gale , Bin Huang , Anthony J. Abbate , Timothy A. Limon , Klaus Kleine
CPC分类号： A61F2/915 , A61F2/82 , A61F2/91 , A61F2002/821 , A61F2210/0004 , A61F2210/0076 , B23K26/384 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29C47/0004 , B29C47/0023 , B29C47/0066 , B29C55/00 , B29C55/24 , B29C65/02 , B29C66/534 , B29C71/0063 , B29C2793/0009 , B29K2995/0039 , B29K2995/006 , B29L2031/7534 , Y10T29/49874 , Y10T29/49908 , Y10T29/49913 , Y10T29/49925 , Y10T29/49927 , Y10T29/49995
摘要： Methods and systems of fabricating a polymeric stent are disclosed herein. Methods are disclosed that include forming a polymeric tube using extrusion, radially deforming the formed tube so that the deformed tube comprises a target diameter, forming a stent from the deformed tube, and forming a stent from the deformed tube. The stent is formed by laser machining a stent pattern in the deformed tube with an ultra-short pulse laser. Disclosed methods further include crimping the stent on a support element, wherein a temperature of the stent during crimping is above an ambient temperature.
摘要翻译： 本文公开了制造聚合物支架的方法和系统。 公开的方法包括使用挤出形成聚合物管，使成形的管径向变形，使得变形的管包括靶直径，从变形的管形成支架，以及从变形的管形成支架。 通过用超短脉冲激光在变形管中激光加工支架图案来形成支架。 公开的方法还包括将支架卷曲在支撑元件上，其中在卷曲期间支架的温度高于环境温度。
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4.发明授权公开(公告)号：US07229471B2
公开(公告)日：2007-06-12
申请号：US10937975
申请日：2004-09-10
CPC分类号： A61L31/141
摘要： Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.
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公开(公告)号：US09561351B2
公开(公告)日：2017-02-07
申请号：US11445079
申请日：2006-05-31
CPC分类号： A61M31/002 , A61F2/88 , A61F2/885 , A61F2250/0039 , A61F2250/0067
摘要： An implantable medical device is disclosed having a helical construct including a set of spiral coils for local in vivo application of a therapeutic substance in a biological lumen. The helical construct is configured to apply less than 0.75 Bar of pressure to the biological lumen wall. The helical construct can have at least two sets of spiral coils having opposing helical directions. The device can be used for the treatment of vascular disorders such as restenosis and vulnerable plaque.
摘要翻译： 公开了一种植入式医疗装置，其具有螺旋构造，其包括用于在生物腔内局部体内施用治疗物质的一组螺旋线圈。 螺旋结构被配置为向生物腔壁施加小于0.75巴的压力。 螺旋结构可以具有至少两组具有相反螺旋方向的螺旋线圈。 该装置可用于治疗血管疾病如再狭窄和易损斑块。
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公开(公告)号：US08894900B2
公开(公告)日：2014-11-25
申请号：US12247164
申请日：2008-10-07
IPC分类号： B29C70/74
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2250/0029
摘要： A stent for treating a bodily lumen with a flexible section in a high strain region is disclosed. A flexible section may be selectively positioned to reduce an amount of strain in the high strain region when subjected to the applied stress during use to inhibit or prevent fracturing in the high strain region.
摘要翻译： 公开了一种用于在高应变区域中用柔性部分处理身体管腔的支架。 柔性部分可以选择性地定位成在使用过程中受到施加的应力时，在高应变区域中减小应变量，以抑制或防止高应变区域中的断裂。
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公开(公告)号：US08373090B2
公开(公告)日：2013-02-12
申请号：US12554764
申请日：2009-09-04
IPC分类号： B23K26/14
CPC分类号： B23K26/38 , A61F2/91 , B23K26/0823 , B23K26/14 , B23K26/147 , B23K26/702 , B23K2101/06 , B23K2103/42 , B23K2103/50 , B26D2003/285 , B26D2003/288 , Y10T83/0596 , Y10T83/748
摘要： Apparatus, method and system for cutting a polymeric stent including the use of a polymeric mandrel as a laser shielding device. The polymeric mandrel is allowed to roll freely within a polymeric tube that is cut into a polymeric stent.
摘要翻译： 用于切割聚合物支架的装置，方法和系统，包括使用聚合物心轴作为激光屏蔽装置。 允许聚合物心轴在切割成聚合物支架的聚合物管内自由滚动。
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公开(公告)号：US08066762B2
公开(公告)日：2011-11-29
申请号：US12579359
申请日：2009-10-14
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91575 , A61F2230/0013 , A61F2240/001 , A61L31/04 , A61L31/14
摘要： A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are used, while simultaneously reducing damage to the inner surface of the stent due to the shielding effect of the polymeric mandrel.
摘要翻译： 聚合物管定位在聚合物心轴上，然后激光切割以形成可植入的医疗装置，例如支架。 该方法减少了支架内表面的污染，如果使用传统的玻璃或金属心轴，则会由于聚合物心轴的屏蔽作用而同时减少对支架内表面的损伤。
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公开(公告)号：US07740791B2
公开(公告)日：2010-06-22
申请号：US11479111
申请日：2006-06-30
申请人： Klaus Kleine , David C. Gale
发明人： Klaus Kleine , David C. Gale
IPC分类号： H05B6/00
CPC分类号： B29C49/0073 , A61F2/844 , A61F2/91 , A61F2/915 , A61F2210/0004 , A61F2230/0067 , A61F2230/0069 , A61F2240/001 , A61F2250/0068 , B29C49/4278 , B29C49/48 , B29C49/54 , B29C2049/0089 , B29C2793/009 , B29K2067/046 , B29K2995/0056 , B29L2031/7534
摘要： The invention provides a method of manufacturing a stent, the method comprising: disposing a polymeric tube into a cylindrical mold, the cylindrical mold having a variable diameter along a portion of the inside surface of the mold; radially expanding the tube by blowing a gas or liquid into the cylindrical mold, the outside surface of the tube conforming to the variable diameter portion of the outside surface of the mold, causing the radially expanded tube to have a variable diameter along the conformed length of the tube; and fabricating a stent from the expanded tube.
摘要翻译： 本发明提供了一种制造支架的方法，所述方法包括：将聚合物管设置在圆柱形模具中，所述圆柱形模具沿着所述模具的内表面的一部分具有可变直径; 通过将气体或液体吹送到圆柱形模具中，使管的外表面与模具的外表面的可变直径部分相符，使得径向膨胀的管具有沿着合适的长度的可变直径 管子 并从扩张管制造支架。
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10.发明申请Compositions Containing Fast-Leaching Plasticizers For Improved Performance Of Medical Devices 审中-公开包含快速浸出增塑剂的组合物可改善医疗器械的性能公开(公告)号：US20100137471A1
公开(公告)日：2010-06-03
申请号：US12651300
申请日：2009-12-31
IPC分类号： A61L27/14
CPC分类号： A61L31/141
摘要： Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided.
摘要翻译： 提供了包含临时增塑剂的医疗植入物，生产这种植入物的方法，以及使用植入物治疗疾病或改善其一种或多种症状的方法。
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