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    Curable Resin Composition and Cold Setting Adhesive
    5.
    发明申请
    Curable Resin Composition and Cold Setting Adhesive 有权
    可固化树脂组合物和冷定型粘合剂

    公开(公告)号：US20090264602A1

    公开(公告)日：2009-10-22

    申请号：US12494540

    申请日：2009-06-30

    申请人： Shigeki Mori ,  Yukihiro Nomura ,  Kazuhiro Iyo ,  Shinichi Sato

    发明人： Shigeki Mori ,  Yukihiro Nomura ,  Kazuhiro Iyo ,  Shinichi Sato

    IPC分类号： C08L77/00 ,  C08L83/00 ,  C08L75/04 ,  C08L61/00 ,  C08L83/05

    CPC分类号： C08L101/10 ,  C08G18/10 ,  C08G18/4825 ,  C08G18/4837 ,  C08G18/755 ,  C09J175/08 ,  C08G18/289

    摘要： Disclosed is a moisture-curing type curable resin composition containing: a curable resin intramolecularly having a silicon-containing functional group; and a Lewis acid or a complex of the Lewis acid as a curing catalyst, the Lewis acid being selected from the group consisting of metal halides and boron halides, which is rapidly cured at room temperature. The silicon-containing functional group is represented by general formula: —SiX1X2X3 or —SiR1X1 X2 (wherein, X1, X2 and X3 respectively represent a hydrolytic group and may be the same as or different from each other, and R1 represents a substituted or unsubstituted organic group having 1 to 20 carbons). If the silicon-containing functional group is —SiR1X1 X2, the curable resin further contains intramolecularly a polar component that is one of urethane, thiourethane, urea, thiourea, substituted urea, substituted thiourea, amide, and sulfide bonds, and hydroxyl, secondary amino and tertiary amino groups. Two-part type adhesive is constitutible with separating the curable resin from the curing catalyst.

    摘要翻译： 公开了一种湿固化型固化性树脂组合物，其含有：分子内具有含硅官能团的固化性树脂; 路易斯酸或作为固化催化剂的路易斯酸的络合物，所述路易斯酸选自金属卤化物和卤化硼，其在室温下快速固化。 含硅官能团由以下通式表示：-SiX1X2X3或-SiR1X1 X2（其中，X1，X2和X3分别表示水解基团，可以相同或不同，R1表示取代或未取代的 碳原子数为1〜20的有机基团）。 如果含硅官能团为-SiR1X1 X2，则固化性树脂还分子内含有氨基甲酸酯，硫代氨基甲酸酯，脲，硫脲，取代的脲，取代的硫脲，酰胺和硫键之一的极性成分，羟基，仲氨基 和叔氨基。 两部分型粘合剂是可固化树脂与固化催化剂分离的组成成分。

    Release-Control Composition
    6.
    发明申请
    Release-Control Composition 有权
    释放控制组成

    公开(公告)号：US20090053308A1

    公开(公告)日：2009-02-26

    申请号：US11885467

    申请日：2006-03-03

    申请人： Hajime Ishida ,  Yukihiro Nomura

    发明人： Hajime Ishida ,  Yukihiro Nomura

    IPC分类号： A61K9/62 ,  A61K9/56 ,  A61K9/58 ,  A61P35/00 ,  A61K9/14 ,  A61K31/4188

    CPC分类号： A61K9/5078 ,  A61K9/4816 ,  A61K9/4866 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5047 ,  A61K31/4164 ,  A61K31/4188

    摘要： The present invention relates to a controlled release capsule preparation for oral administration, which contains (i) a granule containing a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring optionally having substituent(s), or a salt thereof, and a hydrophilic polymer, and coated with an enteric coating agent and the like, and (ii) a fluidizer. According to the present invention, a controlled release composition for oral administration of an imidazole derivative, which has steroid C17,20-lyase inhibiting activity and which has remarkably improved sustainability of the blood concentration, is provided.

    摘要翻译： 本发明涉及口服给药的控释胶囊制剂，其包含（i）含有下式表示的化合物的生理活性物质的颗粒：其中n为1〜3的整数，Ar为芳香族 任选具有取代基的环或其盐和亲水性聚合物，并用肠溶衣剂等涂布，和（ii）流化剂。 根据本发明，提供了具有类固醇C17,20-裂解酶抑制活性并显着改善血液浓度可持续性的咪唑衍生物的口服给药组合物。

    Curable resin composition and cold-setting adhesive
    7.
    发明申请
    Curable resin composition and cold-setting adhesive 失效
    可固化树脂组合物和冷固粘合剂

    公开(公告)号：US20060189736A1

    公开(公告)日：2006-08-24

    申请号：US10564843

    申请日：2004-07-16

    申请人： Shigeki Mori ,  Yukihiro Nomura ,  Kazuhiro Iyo ,  Shinichi Sato

    发明人： Shigeki Mori ,  Yukihiro Nomura ,  Kazuhiro Iyo ,  Shinichi Sato

    IPC分类号： C08K3/38

    CPC分类号： C08L101/10 ,  C08G18/10 ,  C08G18/4825 ,  C08G18/4837 ,  C08G18/755 ,  C09J175/08 ,  C08G18/289

    摘要： Disclosed is a moisture-curing type curable resin composition containing: a curable resin intramolecularly having a silicon-containing functional group; and a Lewis acid or a complex of the Lewis acid as a curing catalyst, the Lewis acid being selected from the group consisting of metal halides and boron halides, which is rapidly cured at room temperature. The silicon-containing functional group is represented by general formula: —SiX1X2X3 or —SiR1X1X2 (wherein, X1, X2 and X3 respectively represent a hydrolytic group and may be the same as or different from each other, and R1 represents a substituted or unsubstituted organic group having 1 to 20 carbons). If the silicon-containing functional group is —SiR1X1X2, the curable resin further contains intramolecularly a polar component that is one of urethane, thiourethane, urea, thiourea, substituted urea, substituted thiourea, amide, and sulfide bonds, and hydroxyl, secondary amino and tertiary amino groups. Two-part type adhesive is constitutible with separating the curable resin from the curing catalyst.

    摘要翻译： 公开了一种湿固化型固化性树脂组合物，其含有：分子内具有含硅官能团的固化性树脂; 路易斯酸或作为固化催化剂的路易斯酸的络合物，所述路易斯酸选自金属卤化物和卤化硼，其在室温下快速固化。 含硅官能团由以下通式表示：-SiX 1 X 2 X 3或-SiR 1 O / X 1 2 X 2（其中，X 1，X 2，X 3和X 3） >分别表示水解基团，可以相同也可以不同，R 1表示取代或未取代的碳原子数1〜20的有机基团）。 如果含硅官能团是-SiR 1 X 1 X 2 O 2，那么可固化树脂还分子内含有极性组分，其为 氨基甲酸酯，硫代氨基甲酸酯，脲，硫脲，取代的脲，取代的硫脲，酰胺和硫键，以及羟基，仲氨基和叔氨基。 两部分型粘合剂是可固化树脂与固化催化剂分离的组成成分。

    Antioxidizing composition
    8.
    发明授权
    Antioxidizing composition 失效
    抗氧化组合物

    公开(公告)号：US4765927A

    公开(公告)日：1988-08-23

    申请号：US893887

    申请日：1986-08-06

    申请人： Yukihiro Nomura ,  Yoko Okuda

    发明人： Yukihiro Nomura ,  Yoko Okuda

    IPC分类号： A23D7/06 ,  A23D9/06 ,  C09K15/06 ,  C09K15/08 ,  C09K15/32 ,  C11B5/00

    CPC分类号： C11B5/0007 ,  C11B5/0092

    摘要： This invention relates to an antioxidizing composition which comprises an antioxidant such as tocopherol, BHT or BHA; condensed phosphate such as pentapolyphosphate; and citric acid. The antioxidizing composition has antioxidant action superior to conventional compositions and has good compatibility with fat, oil and food containing fat or oil. The antioxidizing composition preferably comprises tocopherol, lecithin, pentapolyphosphate and citric acid.

    摘要翻译： 本发明涉及抗氧化组合物，其包含抗氧化剂如生育酚，BHT或BHA; 缩聚磷酸盐如五聚磷酸盐; 和柠檬酸。 抗氧化组合物具有优于常规组合物的抗氧化作用，并且与脂肪，油和含有脂肪或油的食品具有良好的相容性。 抗氧化组合物优选包含生育酚，卵磷脂，五聚磷酸盐和柠檬酸。

    PHARMACEUTICAL COMPOSITION
    10.
    发明申请
    PHARMACEUTICAL COMPOSITION 审中-公开
    药物组合物

    公开(公告)号：US20100016382A1

    公开(公告)日：2010-01-21

    申请号：US12310075

    申请日：2007-08-09

    申请人： Yukihiro Nomura ,  Muneo Nonomura

    发明人： Yukihiro Nomura ,  Muneo Nonomura

    IPC分类号： A61K31/4245 ,  A61P9/12

    CPC分类号： A61K31/4245 ,  A61K9/2018 ,  A61K9/2054

    摘要： The present invention provides a solid pharmaceutical composition superior in the stability and dissolution property, wherein the drug dissolution property of a solid dosage form containing a fat and oil-like substance having a low melting point is improved.The present invention provides a solid pharmaceutical composition containing an active ingredient, a fat and oil-like substance having a low melting point and a low viscosity binder, and a method of improving dissolution of an active ingredient from a solid pharmaceutical composition containing the active ingredient and a fat and oil-like substance having a low melting point, which includes using a low viscosity binder.

    摘要翻译： 本发明提供了稳定性和溶解性优异的固体药物组合物，其中含有具有低熔点的脂肪和油状物质的固体剂型的药物溶解性提高。 本发明提供一种固体药物组合物，其含有活性成分，具有低熔点和低粘度粘合剂的脂肪和油状物质，以及改善活性成分从含有活性成分的固体药物组合物溶解的方法 和具有低熔点的脂肪和油状物质，其包括使用低粘度粘合剂。