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公开(公告)号：US08709780B2
公开(公告)日：2014-04-29
申请号：US13121625
申请日：2009-09-29
IPC分类号： C12N7/02 , A61K39/145
CPC分类号： C07K1/22 , A61K39/00 , A61K39/12 , A61K39/145 , A61K2039/5252 , C07K14/005 , C12N7/00 , C12N2760/16122 , C12N2760/16134 , C12N2760/16151
摘要： The present invention aims to provide a method which enables efficient removal of impurities such as the host proteins from an influenza virus culture liquid by a simple operation, allowing separation and purification of an influenza virus antigen. The method of the present invention for producing a purified influenza virus antigen comprises the step of treating a sample containing an influenza virus with a surfactant, the step of bringing the sample after the treatment into contact with hydroxyapatite in the presence of the surfactant, and the step of recovering a hydroxyapatite-non-adsorbed fraction.
摘要翻译： 本发明的目的在于提供一种能够通过简单的操作从流感病毒培养液中有效去除诸如宿主蛋白质的杂质的方法，从而允许流感病毒抗原的分离和纯化。 本发明的用于制备纯化的流感病毒抗原的方法包括用表面活性剂处理含有流感病毒的样品的步骤，在表面活性剂存在下将处理后的样品与羟基磷灰石接触的步骤， 回收羟基磷灰石非吸附级分的步骤。
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公开(公告)号：US20110182940A1
公开(公告)日：2011-07-28
申请号：US13121625
申请日：2009-09-29
CPC分类号： C07K1/22 , A61K39/00 , A61K39/12 , A61K39/145 , A61K2039/5252 , C07K14/005 , C12N7/00 , C12N2760/16122 , C12N2760/16134 , C12N2760/16151
摘要： The present invention aims to provide a method which enables efficient removal of impurities such as the host proteins from an influenza virus culture liquid by a simple operation, allowing separation and purification of an influenza virus antigen.The method of the present invention for producing a purified influenza virus antigen comprises the step of treating a sample containing an influenza virus with a surfactant, the step of bringing the sample after the treatment into contact with hydroxyapatite in the presence of the surfactant, and the step of recovering a hydroxyapatite-non-adsorbed fraction.
摘要翻译： 本发明的目的在于提供一种能够通过简单的操作从流感病毒培养液中有效去除诸如宿主蛋白质的杂质的方法，从而允许流感病毒抗原的分离和纯化。 本发明的用于制备纯化的流感病毒抗原的方法包括用表面活性剂处理含有流感病毒的样品的步骤，在表面活性剂存在下将处理后的样品与羟基磷灰石接触的步骤， 回收羟基磷灰石非吸附级分的步骤。
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公开(公告)号：US20070277930A1
公开(公告)日：2007-12-06
申请号：US11663071
申请日：2005-09-14
申请人： Toshi Yokoyama , Seiji Katsuoka , Takahiro Ogawa , Kaoru Yamada , Kazuaki Maeda
发明人： Toshi Yokoyama , Seiji Katsuoka , Takahiro Ogawa , Kaoru Yamada , Kazuaki Maeda
IPC分类号： H01L21/304 , H01L21/683
CPC分类号： H01L21/67051 , H01L21/67207
摘要： A substrate cleaning apparatus does not need positioning of a transport system on start-up of the apparatus and can reduce the installation area of the apparatus. The substrate cleaning apparatus includes a base-integrated frame (1) in which are mounted a substrate transport device (2) for transporting a substrate, at least one substrate processing unit (3) for processing the substrate, a substrate loading port (5) for placing a substrate-housing cassette (4) on it, and a processing liquid supply apparatus (6) for supplying a processing liquid to the substrate processing unit, wherein maintenance of the substrate processing unit (3) can be performed from the backside of the apparatus.
摘要翻译： 基板清洗装置不需要在装置起动时定位运输系统，并且可以减少装置的安装面积。 基板清洗装置包括基底一体化框架（1），其中安装有用于输送基板的基板输送装置（2），用于处理基板的至少一个基板处理单元（3），基板装载口（5） 用于将衬底容纳盒（4）放置在其上，以及处理液体供应装置（6），用于向衬底处理单元提供处理液体，其中可以从衬底处理单元（3）的背面执行维护 该装置。
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公开(公告)号：US09138854B2
公开(公告)日：2015-09-22
申请号：US12379983
申请日：2009-03-05
申请人： Kazuaki Maeda , Tamami Takahashi , Masaya Seki , Hiroaki Kusa
发明人： Kazuaki Maeda , Tamami Takahashi , Masaya Seki , Hiroaki Kusa
CPC分类号： B24B21/002 , B24B9/065 , B24B21/004 , B24B21/06 , B24B21/08 , B24B37/04 , B24B41/06
摘要： A polishing apparatus polishes a periphery of a substrate by bringing a polishing tool into sliding contact with the substrate. The polishing apparatus includes a substrate-holding mechanism configured to hold a substrate and rotate the substrate, a polishing mechanism configured to press a polishing tool against a periphery of the substrate so as to polish the periphery, and a periphery-supporting mechanism configured to support the periphery of the substrate by a fluid. The periphery-supporting mechanism is configured to support a surface of the substrate from an opposite side or the same side of the periphery of the substrate.
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公开(公告)号：US20120244220A1
公开(公告)日：2012-09-27
申请号：US13514010
申请日：2010-11-08
摘要： The present invention provides an atorvastatin-containing coated preparation comprising a solid formulation containing atorvastatin, a pharmacologically acceptable atorvastatin salt, or a solvate thereof coated with a coating agent comprising a polyvinyl alcohol copolymer, a method for inhibiting generation of related substances of atorvastatin, a pharmacologically acceptable atorvastatin salt, or a solvate thereof, comprising coating the solid formulation with a coating agent comprising a polyvinyl alcohol copolymer, and a method for stabilizing atorvastatin, a pharmacologically acceptable atorvastatin salt, or a solvate thereof.
摘要翻译： 本发明提供含有阿托伐他汀的包衣制剂，其包含含有阿托伐他汀的固体制剂，药理学上可接受的阿托伐他汀盐或其包衣剂的溶剂化物，其包含聚乙烯醇共聚物，抑制阿托伐他汀相关物质产生的方法 药理学上可接受的阿托伐他汀盐或其溶剂合物，包括用包含聚乙烯醇共聚物的包衣剂涂覆固体制剂，以及稳定阿托伐他汀的方法，药理学上可接受的阿托伐他汀盐或其溶剂合物。
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公开(公告)号：US20120267292A1
公开(公告)日：2012-10-25
申请号：US13447518
申请日：2012-04-16
申请人： Tamami Takahashi , Kazuaki Maeda , Masanori Goto
发明人： Tamami Takahashi , Kazuaki Maeda , Masanori Goto
IPC分类号： B01D61/00
CPC分类号： C02F1/441 , B01D61/06 , B01D2313/246 , C02F1/006 , C02F2103/08 , C02F2201/003 , C02F2301/022 , C02F2303/10 , Y02A20/131 , Y02W10/30
摘要： An energy exchange chamber is used for exchanging pressure energy between concentrated seawater discharged from a reverse-osmosis membrane-separation apparatus and a part of seawater to be treated by the reverse-osmosis membrane separation apparatus in a seawater desalination system. The energy exchange chamber includes a concentrated seawater distributor communicating with a concentrated seawater port and configured to distribute a flow of the concentrated seawater flowing therein all over a horizontal plane of an interior of a chamber, and a seawater distributor communicating with a seawater port and configured to distribute a flow of the seawater flowing therein all over a horizontal plane of the interior of the chamber. The concentrated seawater and the seawater introduced into the chamber are brought into direct contact with each other over the horizontal plane of the interior of the chamber to exchange pressure energy between the concentrated seawater and the seawater.
摘要翻译： 能量交换室用于在由反渗透膜分离装置排出的浓缩海水与在海水淡化系统中由反渗透膜分离装置进行处理的部分海水之间交换压力能量。 能量交换室包括集中的海水分配器，其与集中的海水端口连通并且被配置为分配在其中流过其中的集中海水的流动在室的内部的水平面上，以及与海水端口连通并配置的海水分配器 以便在室的内部的水平平面上分布流过其中的海水的流动。 引入室中的浓缩海水和海水在室内部的水平面上彼此直接接触，以在集中的海水和海水之间交换压力能量。
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公开(公告)号：US5200893A
公开(公告)日：1993-04-06
申请号：US484888
申请日：1990-02-26
申请人： Kuniaki Ozawa , Hiroshi Kinukawa , Kazuaki Maeda
发明人： Kuniaki Ozawa , Hiroshi Kinukawa , Kazuaki Maeda
CPC分类号： G06F17/2881 , G06F17/243 , G06F17/271
摘要： A computer aided text generation system and method provides functions of aiding a logical outline structure of a text, aiding the text generation using a conventional expression, aiding the text generation without using conventional expression, aiding the refinement of the generated text and aiding the collection of illustrative sentences. The present system permits generation of a finished text of high quality.
摘要翻译： 计算机辅助文本生成系统和方法提供了帮助文本的逻辑轮廓结构的功能，使用常规表达来辅助文本生成，辅助文本生成而不使用传统表达，帮助细化生成的文本并协助收集 说明性句子。 本系统允许产生高质量的完成文本。
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公开(公告)号：US06269548B1
公开(公告)日：2001-08-07
申请号：US09172147
申请日：1998-10-14
IPC分类号： F26B1724
CPC分类号： H01L21/68792 , F16C2300/62
摘要： A spin processing apparatus can prevent contamination of workpieces by wear particles, and can operate at high efficiency while lowering the noise level associated with the operation of the apparatus. The spin processing apparatus includes a chamber, a spin holder disposed inside the chamber for holding workpieces, and driver device for rotating the spin holder. A supporting device is provided for rotatably supporting the spin holder in a non-contact manner through a magnetically-operated mechanism.
摘要翻译： 旋转处理装置可以防止磨损颗粒对工件的污染，并且可以在降低与装置的操作相关的噪声水平的同时高效率地操作。 旋转处理装置包括：室，设置在室内用于保持工件的旋转架，以及用于旋转旋转架的驱动装置。 提供支撑装置，用于通过磁力操作机构以非接触方式可旋转地支撑旋转保持器。
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公开(公告)号：US09011688B2
公开(公告)日：2015-04-21
申请号：US13447518
申请日：2012-04-16
申请人： Tamami Takahashi , Kazuaki Maeda , Masanori Goto
发明人： Tamami Takahashi , Kazuaki Maeda , Masanori Goto
IPC分类号： B01D61/06 , C02F1/44 , C02F1/00 , C02F103/08
CPC分类号： C02F1/441 , B01D61/06 , B01D2313/246 , C02F1/006 , C02F2103/08 , C02F2201/003 , C02F2301/022 , C02F2303/10 , Y02A20/131 , Y02W10/30
摘要： An energy exchange chamber is used for exchanging pressure energy between concentrated seawater discharged from a reverse-osmosis membrane-separation apparatus and a part of seawater to be treated by the reverse-osmosis membrane separation apparatus in a seawater desalination system. The energy exchange chamber includes a concentrated seawater distributor communicating with a concentrated seawater port and configured to distribute a flow of concentrated seawater all over a horizontal plane of an interior of a chamber, and a seawater distributor communicating with a seawater port and configured to distribute a flow of seawater all over the horizontal plane of the interior of the chamber. The concentrated seawater and the seawater introduced into the chamber are brought into direct contact with each other over the horizontal plane of the interior of the chamber to exchange pressure energy between the concentrated seawater and the seawater introduced into the chamber.
摘要翻译： 能量交换室用于在由反渗透膜分离装置排出的浓缩海水与在海水淡化系统中由反渗透膜分离装置进行处理的部分海水之间交换压力能量。 能量交换室包括集中的海水分配器，其与集中的海水端口连通并且构造成在室的内部的整个水平面上分布集中的海水流;以及海水分配器，其与海水端口连通并且被配置为分配 在整个室内水平面上的海水流动。 引入室中的浓缩海水和海水在室的内部的水平面上彼此直接接触，以在集中的海水和引入室中的海水之间交换压力能量。
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公开(公告)号：US20090227189A1
公开(公告)日：2009-09-10
申请号：US12379983
申请日：2009-03-05
申请人： Kazuaki Maeda , Tamami Takahashi , Masaya Seki , Hiroaki Kusa
发明人： Kazuaki Maeda , Tamami Takahashi , Masaya Seki , Hiroaki Kusa
CPC分类号： B24B21/002 , B24B9/065 , B24B21/004 , B24B21/06 , B24B21/08 , B24B37/04 , B24B41/06
摘要： A polishing apparatus polishes a periphery of a substrate by bringing a polishing tool into sliding contact with the substrate. The polishing apparatus includes a substrate-holding mechanism configured to hold a substrate and rotate the substrate, a polishing mechanism configured to press a polishing tool against a periphery of the substrate so as to polish the periphery, and a periphery-supporting mechanism configured to support the periphery of the substrate by a fluid. The periphery-supporting mechanism is configured to support a surface of the substrate from an opposite side or the same side of the periphery of the substrate.
摘要翻译： 抛光装置通过使抛光工具与基板滑动接触来抛光基板的周边。 抛光装置包括：基板保持机构，其构造成保持基板并使基板旋转;抛光机构，其构造成将抛光工具抵靠基板的周边按压以周边抛光;以及周边支撑机构，其构造成支撑 通过流体的衬底的周边。 周边支撑机构构造成从基板的周边的相对侧或同一侧支撑基板的表面。
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