摘要:
A polarization insensitive fiber laser. A pair of 45 degree Faraday rotators are positioned on either end of the fiber gain source. The resulting laser is insensitive to external perturbations with respect to known entrance and exit polarization states of the laser light. Modelocking, both passive and active, is possible. Configuration wherein the fiber is a combination of polarization preserving and Erbium-doped, and a saturable absorber is included provide a self-starting, polarization insensitive modelocked laser.
摘要:
A CPM mode-locked fiber ring laser including an ion-implanted semiconductor saturable absorber providing sub-picosecond pulses at rapid repetition rates. The laser provides compact, turn-key capability and is polarization insensitive.
摘要:
A figure-8 loop laser having a controllable phase shifter in a Sagnac loop (non-linear amplifying loop mirror). A half-wave plate in series with Faraday optical rotators provide a switchable non-reciprocal 180-degree phase shifter that allows the birefringence of the fiber loop to be adjusted during continuous wave operation. The phase shifter is activated during continuous wave operation to find a minimum threshold and then is turned off, placing the laser in optimum state for mode locking.
摘要:
A switching device for controlling fluid motion. The device includes a capillary filled with a first fluid into which a wall-confined bubble of a second fluid is introduced to achieve a first switching event. Capillary geometry and wetting properties provide a pressure-related asymmetric energy potential distribution for controlling the flow of the bubble, and the device is called an asymmetric bubble chamber, or ABC. The bubble is initially trapped in an energy potential well, and upon increase of its volume moves from the well into a region of low energy potential to achieve a second switching event. The first switching event may be blocking of a fluid channel or reflection of an optical beam in an optical crosspoint switch, while the second switching event may be unblocking of a fluid channel or restoration of transmission of an optical beam. The increase in bubble volume between the first and second switching events can act as the stroke of a fluidic piston to pump a volume the first fluid within the capillary. The device can be employed to thermally degas a liquid. The use of large-magnitude geometry-related energy potentials permits rapid cyclical operation of the device in a manner resistant to mechanical shock.
摘要:
A thermal optical switching cell has a channel of either gas or boilable liquid that crosses an optical waveguide at a forty-five degree angle. Two or more appropriately placed heaters use the water/steam/dry states of thermal ink jet technology to quickly insert, or extract, boilable liquid respectively into, or from, the channel. The boilable liquid has an index of refraction close to that of the guide. In the wet state, the channel contains the liquid and nearly all the light of the incoming guide traverses the liquid along the axis of the guide. In the dry state, the channel contains gas. Total internal reflection (TIR) occurs and light is directed at right angles away from the axis of the incoming channel. Adding a second waveguide, perpendicular to, and intersecting the first waveguide at the channel, forms a cross-bar switch. These liquid switching cells toggle between the wet and dry states. No power is required to hold the switch in the most recent state. A monitoring signal is described that can be used to determine the state of the switch. The dry state of these cells is totally internally reflecting. The wet state, however, is transmissive with a small, but objectionable, amount of reflection. A push-pull optical circuit is formed using paired cells and at least one TIR mirror. One of the cells of the circuit is always in the TIR state to provide good isolation. This circuit has the property of reporting the state of the switch-pair so that a fault can be detected. If a fault is detected, repeated activation pulses can be applied to force liquid into the correct places to maintain proper operation of the circuit.
摘要:
There are described compounds of formula I, ##STR1## wherein R.sup.1 represents H or OH; R.sup.2 represents H; in addition, R.sup.1 and R.sup.2 may together represent a second carbon-carbon bond between the carbon atoms to which they are attached; R.sup.3 represents OH or OCH.sub.3 ; X represents O or (H,OH); and Y represents O or N--OR.sup.4, in which R.sup.4 represents H or alkyl C.sub.1-6 ; provided that when R.sup.1 is OH, R.sup.2 is H and X is O, then Y does not represent O.Processes for their production and compositions containing them, eg. for use as immunosuppressive agents, are also described.
摘要:
This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 represents lower alkyl, phenyl or phenyl lower alkyl;R.sub.2 and R.sub.4 represent lower alkyl; andR.sub.3 represents lower alkyl, benzyloxyalkyl, alkoxybenzyl or benzyloxybenzyl wherein the oxyalkyl or alkoxy moiety contain 1 to 6 carbon atoms; and a, b, and c represent chiral centers with optional R or S stereochemistry. These compounds inhibit collagenase and are useful in the treatment of arthritis. Also disclosed are processes for manufacture of the compounds and pharmaceutical compositions containing them.
摘要:
A thermally-activated gas extraction device that comprises a bubble capture chamber, an exhaust manifold, a tapered extraction chamber and an extraction heater associated with the tapered extraction chamber. The tapered extraction chamber extends from the bubble capture chamber towards the exhaust manifold and has a cross-sectional area that increases towards the exhaust manifold. A gas removal method in which the gas extraction device is provided, a bubble of gas is accumulated in the bubble capture chamber, a portion of the liquid in the tapered extraction chamber heated to nucleate a bubble of vapor, and the bubble of vapor is heated to explosively expand the bubble of vapor into contact with the walls of the tapered extraction chamber and into contact with the bubble of gas to form a composite bubble. Contact with the walls of the tapered extraction moves the composite bubble towards the exhaust manifold. Finally, heating of the composite bubble is discontinued to condense the vapor in the composite bubble.
摘要:
A switching element defines a transmitting state and a reflecting state for a pair of intersecting waveguides that have a gap at their intersection. In the preferred embodiment, the switching element exhibits total internal reflection at the gap sidewall from one waveguide to the other when not in the transmitting state. In the transmitting state, index-matching liquid fills the gap, enabling light to continue in the original waveguide direction. The switching element may use ink jet techniques or bubble techniques to displace index-matching liquid. The index-matching fluid may be projected from a gap between the waveguides by a jet mechanism, or a vapor or dissolved gas bubble may be formed to fill the gap between the waveguides to provide the reflecting state for the switching element. Using either of the techniques, heaters are employed to initiate the switching operation. In some embodiments, more than one heater is utilized. In the preferred embodiment, waveguides are formed on one substrate and heaters are formed on another. Then the substrates are aligned and bonded together to position the heaters in very close proximity to the intersection between the waveguides. Preferably, the switching element is one element in a matrix of such elements for routing signals between arrays of input and output waveguides.
摘要:
Thid disclosure relates to a novel class of hydroxamic acid based collagenase inhibitor derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions in the treatment of collagenase induced diseases.