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1.发明授权Method for the treatment of joint diseases characterized by unwanted pannus 失效治疗以不需要的血管diseases病为特征的关节疾病的方法
公开(公告)号：US6074352A
公开(公告)日：2000-06-13
申请号：US48866
申请日：1998-03-26
CPC分类号： A61N7/00
摘要： The present invention describes methods for the treatment of joint diseases characterized by unwanted pannus, e.g., arthritis. The method involves the introduction of ultrasound energy into the inflamed cells or pannus of the joint to be treated resulting in destruction and/or modification of the pannus.
摘要翻译： 本发明描述了治疗以不需要的血管us diseases（例如关节炎）为特征的关节疾病的方法。 该方法涉及将超声能量引入待治疗的关节的发炎细胞或血管treated，导致砧骨的破坏和/或修饰。
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2.发明授权Double-structured tissue implant and a method for preparation and use thereof 有权双重结构的组织植入物及其制备和使用方法公开(公告)号：US08685107B2
公开(公告)日：2014-04-01
申请号：US11894124
申请日：2007-08-20
IPC分类号： A61F2/02
CPC分类号： A61L27/48 , A61F2002/0086 , A61F2210/0076 , A61F2310/00371 , A61F2310/00982 , A61L27/24 , A61L27/3817 , A61L27/54 , A61L27/56 , A61L2400/18 , A61L2430/34 , C08L89/06
摘要： A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
摘要翻译： 双组织组织植入物及其制备和使用方法，用于植入组织缺陷。 双重结构的组织植入物包括主要支架和由可溶性胶原溶液组合的辅助支架，所述可溶性胶原溶液与产生并定位在主要支架内的非离子表面活性剂组合。 独立的二次支架植入物或单位。 制备双结构植入物或独立的第二支架的方法，其包括冻干和脱水热处理。
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3.发明申请Double-structured tissue implant and a method for preparation and use thereof 有权双重结构的组织植入物及其制备和使用方法公开(公告)号：US20090012627A1
公开(公告)日：2009-01-08
申请号：US11894124
申请日：2007-08-20
CPC分类号： A61L27/48 , A61F2002/0086 , A61F2210/0076 , A61F2310/00371 , A61F2310/00982 , A61L27/24 , A61L27/3817 , A61L27/54 , A61L27/56 , A61L2400/18 , A61L2430/34 , C08L89/06
摘要： A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
摘要翻译： 双组织组织植入物及其制备和使用方法，用于植入组织缺陷。 双重结构的组织植入物包括主要支架和由可溶性胶原溶液组合的辅助支架，所述可溶性胶原溶液与产生并定位在主要支架内的非离子表面活性剂组合。 独立的二次支架植入物或单位。 制备双结构植入物或独立的第二支架的方法，其包括冻干和脱水热处理。
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公开(公告)号：US20170312391A1
公开(公告)日：2017-11-02
申请号：US15631699
申请日：2017-06-23
CPC分类号： A61L27/48 , A61F2002/0086 , A61F2210/0076 , A61F2310/00371 , A61F2310/00982 , A61L27/24 , A61L27/3817 , A61L27/54 , A61L27/56 , A61L2400/18 , A61L2430/34 , C08L89/06
摘要： A double-structured tissue implant and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit. A process for preparation of the double-structured implant or the stand alone secondary scaffold comprising lyophilization and dehydrothermal treatment.
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公开(公告)号：US20160206787A9
公开(公告)日：2016-07-21
申请号：US12195255
申请日：2008-08-20
申请人： Sonya Shortkroff , Joseph Khoury , Laurence J.B. Tarrant , Hans P.I. Claesson , Robert Lane Smith
发明人： Sonya Shortkroff , Joseph Khoury , Laurence J.B. Tarrant , Hans P.I. Claesson , Robert Lane Smith
IPC分类号： A61F2/02 , A61L27/56 , A61F2/30 , A61L27/52 , A61L27/26 , A61L27/54 , A61L27/24 , A61B17/08 , A61L27/38
CPC分类号： A61F2/02 , A61F2/08 , A61F2/28 , A61F2/30756 , A61F2002/30766 , A61F2240/001 , A61L27/24 , A61L27/26 , A61L27/3804 , A61L27/3817 , A61L27/3834 , A61L27/3839 , A61L27/3847 , A61L27/3852 , A61L27/386 , A61L27/3873 , A61L27/3878 , A61L27/52 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2430/06 , A61L2430/20 , A61L2430/30 , A61L2430/32 , A61L2430/34
摘要： A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
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6.发明授权Method for use of a double-structured tissue implant for treatment of tissue defects 有权使用双组织植入物治疗组织缺陷的方法公开(公告)号：US08070827B2
公开(公告)日：2011-12-06
申请号：US11982268
申请日：2007-10-31
申请人： Sonya Shortkroff , Laurence J. B. Tarrant , Eric J. Roos , Robert Lane Smith , Hans Peter Ingemar Claesson
发明人： Sonya Shortkroff , Laurence J. B. Tarrant , Eric J. Roos , Robert Lane Smith , Hans Peter Ingemar Claesson
IPC分类号： A61F2/02
CPC分类号： A61L27/48 , A61L27/38 , A61L27/54 , A61L27/56 , A61L2300/254 , A61L2300/258 , A61L2300/41 , A61L2300/414 , A61L2300/416 , A61L2300/426 , A61L2300/428 , A61L2300/43 , A61L2300/802
摘要： A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit.
摘要翻译： 用于双组织植入物或用于治疗组织缺陷的独立植入物的二次支架的方法。 双重结构的组织植入物包括主要支架和由可溶性胶原溶液组合的辅助支架，所述可溶性胶原溶液与产生并定位在主要支架内的非离子表面活性剂组合。 独立的二次支架植入物或单位。
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7.发明申请Method for use of a double-structured tissue implant for treatment of tissue defects 有权使用双组织植入物治疗组织缺陷的方法公开(公告)号：US20090012628A1
公开(公告)日：2009-01-08
申请号：US11982268
申请日：2007-10-31
申请人： Sonya Shortkroff , Laurence J. B. Tarrant , Eric J. Roos , Robert Lane Smith , Hans Peter Claesson
发明人： Sonya Shortkroff , Laurence J. B. Tarrant , Eric J. Roos , Robert Lane Smith , Hans Peter Claesson
IPC分类号： A61F2/02
CPC分类号： A61L27/48 , A61L27/38 , A61L27/54 , A61L27/56 , A61L2300/254 , A61L2300/258 , A61L2300/41 , A61L2300/414 , A61L2300/416 , A61L2300/426 , A61L2300/428 , A61L2300/43 , A61L2300/802
摘要： A method for use of a double-structured tissue implant or a secondary scaffold stand alone implant for treatment of tissue defects. The double-structured tissue implant comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold. A stand alone secondary scaffold implant or unit.
摘要翻译： 用于双组织植入物或用于治疗组织缺陷的独立植入物的二次支架的方法。 双重结构的组织植入物包括主要支架和由可溶性胶原溶液组合的辅助支架，所述可溶性胶原溶液与产生并定位在主要支架内的非离子表面活性剂组合。 独立的二次支架植入物或单位。
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8.发明授权公开(公告)号：US09421304B2
公开(公告)日：2016-08-23
申请号：US12195255
申请日：2008-08-20
申请人： Sonya Shortkroff , Joseph Khoury , Laurence J. B. Tarrant , Hans P. I. Claesson , Robert Lane Smith
发明人： Sonya Shortkroff , Joseph Khoury , Laurence J. B. Tarrant , Hans P. I. Claesson , Robert Lane Smith
CPC分类号： A61F2/02 , A61F2/08 , A61F2/28 , A61F2/30756 , A61F2002/30766 , A61F2240/001 , A61L27/24 , A61L27/26 , A61L27/3804 , A61L27/3817 , A61L27/3834 , A61L27/3839 , A61L27/3847 , A61L27/3852 , A61L27/386 , A61L27/3873 , A61L27/3878 , A61L27/52 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2430/06 , A61L2430/20 , A61L2430/30 , A61L2430/32 , A61L2430/34
摘要： A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
摘要翻译： 双组织植入物（DSTI）及其制备和使用方法，用于植入组织缺陷。 用于分化，生长和转化细胞，干细胞，间充质干细胞和骨髓干细胞的双重结构组织植入物。 DSTI包括主要支架和由可溶性胶原溶液组合的辅助支架，其与产生并定位在主要支架内的非离子表面活性剂组合。
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9.发明申请Method For Improvement Of Differentiation Of Mesenchymal Stem Cells Using A Double-Structured Tissue Implant 有权使用双结构组织植入物改善间充质干细胞分化的方法公开(公告)号：US20090069903A1
公开(公告)日：2009-03-12
申请号：US12195255
申请日：2008-08-20
申请人： Sonya Shortkroff , Joseph Khoury , Laurence J.B. Tarrant , Hans P.I. Claesson , Robert Lane Smith
发明人： Sonya Shortkroff , Joseph Khoury , Laurence J.B. Tarrant , Hans P.I. Claesson , Robert Lane Smith
CPC分类号： A61F2/02 , A61F2/08 , A61F2/28 , A61F2/30756 , A61F2002/30766 , A61F2240/001 , A61L27/24 , A61L27/26 , A61L27/3804 , A61L27/3817 , A61L27/3834 , A61L27/3839 , A61L27/3847 , A61L27/3852 , A61L27/386 , A61L27/3873 , A61L27/3878 , A61L27/52 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2430/06 , A61L2430/20 , A61L2430/30 , A61L2430/32 , A61L2430/34
摘要： A double-structured tissue implant (DSTI) and a method for preparation and use thereof for implantation into tissue defects. The double-structured tissue implant for differentiation, growth and transformation of cells, stem cells, mesenchymal stem cells and bone marrow stem cells. DSTI comprising a primary scaffold and a secondary scaffold consisting of a soluble collagen solution in combination with a non-ionic surfactant generated and positioned within the primary scaffold.
摘要翻译： 双组织植入物（DSTI）及其制备和使用方法，用于植入组织缺陷。 用于分化，生长和转化细胞，干细胞，间充质干细胞和骨髓干细胞的双重结构组织植入物。 DSTI包括主要支架和由可溶性胶原溶液组合的辅助支架，其与产生并定位在主要支架内的非离子表面活性剂组合。
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