High purity alpha lactalbumin and methods of making

    公开(公告)号:US11206846B2

    公开(公告)日:2021-12-28

    申请号:US15947289

    申请日:2018-04-06

    摘要: Methods and systems for making a high-purity α-lactalbumin composition are described. The composition may be made by providing a whey protein mixture, and adding an alkaline solution to the mixture to make the mixture alkaline and promote the aggregation of ß-lactoglobulin proteins. The alkaline whey protein mixture is filtered into a ß-LG aggregate composition and a α-LA enriched composition. A final α-lactalbumin enriched composition sourced from the α-LA enriched composition is dried into the high-purity α-lactalbumin composition (a powdered dairy composition) that is at least 70 wt. % α-lactalbumin on a protein basis. A protease enzyme may optionally be added to the α-LA enriched composition to form an enzymatically treated α-LA enriched composition that becomes the source of the final α-lactalbumin enriched composition.

    ALPHA-LACTALBUMIN ENRICHED WHEY PROTEIN COMPOSITIONS AND METHODS OF MAKING AND USING THEM
    3.
    发明申请
    ALPHA-LACTALBUMIN ENRICHED WHEY PROTEIN COMPOSITIONS AND METHODS OF MAKING AND USING THEM 有权
    ALPHA-LACTALBUMIN丰富的蛋白质组合物及其制备和使用方法

    公开(公告)号:US20140287095A1

    公开(公告)日:2014-09-25

    申请号:US14216445

    申请日:2014-03-17

    IPC分类号: A23J3/34

    摘要: Methods are described for treating a whey protein mixture to increase a relative concentration of α-lactalbumin protein in the mixture. The methods may include the step of adjusting a temperature of the whey protein mixture to about 10° C. or less, and adjusting the pH of the mixture to greater than 7. The may further include adding a protease enzyme to the whey protein mixture that selectively hydrolyzes β-lactoglobulin protein in the mixture. The activity of the protease enzyme in the hydrolyzed whey protein mixture may be terminated before a substantial portion of the α-lactalbumin protein has been hydrolyzed by the enzyme. In some instances, the whey protein mixture may also include glycomacropeptides that are selectively hydrolyzed with the β-lactoglobulin protein. The β-lactoglobulin and glycomacropeptide hydrolysates may be separated to produce an enhanced α-lactalbumin protein composition for infant formula, among other products.

    摘要翻译: 描述了用于处理乳清蛋白混合物以增加混合物中α-乳白蛋白的相对浓度的方法。 所述方法可以包括将乳清蛋白混合物的温度调节至约10℃或更低,并将混合物的pH调节至大于7的步骤。还可以包括向乳清蛋白混合物中加入蛋白酶, 选择性地水解混合物中的β-乳球蛋白。 水解的乳清蛋白混合物中的蛋白酶的活性可以在大部分α-乳白蛋白蛋白质被酶水解之前终止。 在一些情况下,乳清蛋白混合物还可以包括用β-乳球蛋白蛋白质选择性水解的糖巨肽。 可以分离β-乳球蛋白和糖巨肽水解产物以产生增强的用于婴儿配方奶粉的α-乳白蛋白组合物,以及其它产品。

    TANDEM EVAPORATION-DRYING METHODS AND SYSTEMS FOR MAKING POWDERED MILK-DERIVED PRODUCTS

    公开(公告)号:US20210106016A1

    公开(公告)日:2021-04-15

    申请号:US16945304

    申请日:2020-07-31

    摘要: Methods of making a powdered milk product are described. The methods may include providing an aqueous milk-sourced mixture, and evaporating water from the aqueous milk-sourced mixture to produce an evaporated milk-sourced mixture having a total solids concentration of 35 wt. % or more. The evaporated milk-sourced mixture may be dried to form the powdered milk product, which may have less than 6 wt. % water. Systems for making the milk powdered product are also described. The systems may include an evaporator to evaporate water from a supply of a milk-sourced mixture to form an evaporated milk-sourced mixture. They may also include a dryer to dry the evaporated milk-sourced mixture and atomize it into the powdered milk product.

    HIGH PURITY ALPHA LACTALBUMIN AND METHODS OF MAKING

    公开(公告)号:US20180317513A1

    公开(公告)日:2018-11-08

    申请号:US15947289

    申请日:2018-04-06

    IPC分类号: A23C21/06 A23J3/08

    摘要: Methods and systems for making a high-purity α-lactalbumin composition are described. The composition may be made by providing a whey protein mixture, and adding an alkaline solution to the mixture to make the mixture alkaline and promote the aggregation of ß-lactoglobulin proteins. The alkaline whey protein mixture is filtered into a ß-LG aggregate composition and a α-LA enriched composition. A final α-lactalbumin enriched composition sourced from the α-LA enriched composition is dried into the high-purity α-lactalbumin composition (a powdered dairy composition) that is at least 70 wt. % α-lactalbumin on a protein basis. A protease enzyme may optionally be added to the α-LA enriched composition to form an enzymatically treated α-LA enriched composition that becomes the source of the final α-lactalbumin enriched composition.

    LACTOBIONIC ACID PRODUCTION METHODS AND PRODUCTS

    公开(公告)号:US20200239511A1

    公开(公告)日:2020-07-30

    申请号:US16259810

    申请日:2019-01-28

    IPC分类号: C07H15/04 B01D61/44 C12P19/02

    摘要: Systems and methods of making lactobionic acid are described. The systems include two-compartment cation bipolar electrodialysis assemblies having at least one cell that includes a cation ion-exchange membrane and a bipolar membrane. The membranes define the borders of a pair of flow channels for a separate (i) caustic stream and (i) purified lactobionic acid stream. Lactobionate ions in the lactobionic acid stream do not cross a membrane in the electrodialysis assembly, which reduces membrane fouling. The methods include passing a lactobionate salt through a two-compartment cation bipolar electrodialysis assembly. The electrodialysis assembly includes at least one two-compartment cation bipolar membrane cell, and separates the lactobionate salt into a caustic compound and the lactobionic acid. The assembly is designed so the lactobionate ions do not cross an ion exchange membrane in the assembly to form the lactobionic acid, which reduces membrane fouling.