公开(公告)号：US09428800B2

公开(公告)日：2016-08-30

申请号：US14195358

申请日：2014-03-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： John Linton ,  Arrin Katz ,  Colin Brenan ,  Karl Yoder ,  Robert Hess ,  Leila Madrone ,  Robert Ellis ,  Tanya Kanigan ,  Kristine Friesen ,  Thomas Morrison ,  Javier Garcia

IPC: G01N31/22 ,  G01N21/01 ,  G01N21/77 ,  C12Q1/68 ,  B01L3/00 ,  G01N21/03 ,  G01N21/15 ,  G01N21/25 ,  B01L7/00 ,  G01N21/05

CPC classification number: C12Q1/6858 ,  B01L3/5025 ,  B01L3/5027 ,  B01L3/508 ,  B01L3/50853 ,  B01L3/50857 ,  B01L7/52 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/0609 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/0829 ,  B01L2300/16 ,  B01L2300/1822 ,  B01L2300/1838 ,  G01N21/03 ,  G01N21/15 ,  G01N21/253 ,  G01N2021/0346 ,  G01N2021/056 ,  G01N2021/158 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.

Abstract translation: 用于容纳至少一个样品和试剂用于分析的系统。 该系统包括一对平行的盖，其至少一个是透光的，其中一对透光盖形成顶部，并且其中一对形成底部。 框架设置在盖之间，以相对于盖限定内部空间。 框架和盖子彼此相关联以形成壳体，该壳体基本上与液体紧密。 微流体阵列设置在内部体积中。 阵列包括具有一对相对表面的厚度的材料片，以及穿过表面之间的厚度的多个通孔，通孔包含至少一个样品和试剂。

公开(公告)号：US20150038377A1

公开(公告)日：2015-02-05

申请号：US14332171

申请日：2014-07-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Leila Madrone ,  John Linton ,  Colin John Herbert Brenan

IPC: B01L3/02 ,  B01J19/00

CPC classification number: B01L3/0244 ,  B01J19/0046 ,  B01J2219/00283 ,  B01J2219/00286 ,  B01J2219/00317 ,  B01J2219/00387 ,  B01L3/021 ,  B01L2200/025 ,  B01L2200/0642 ,  B01L2200/141 ,  B01L2200/142 ,  B01L2400/027 ,  C40B60/14 ,  Y10T436/2575

Abstract: A liquid dispenser for a microfluidic assay system is described. The dispenser includes at least one transfer pin for transferring a microfluidic sample of liquid to a target receptacle. A pin tip at one end of the transfer pin is structured to cooperate with an opening in the target receptacle. The tip uses a high voltage potential to transfer the sample from the pin to the receptacle.

Abstract translation: 描述了用于微流体测定系统的液体分配器。 分配器包括至少一个传送销，用于将液体的微流体样品转移到目标容器。 传送销的一端处的销尖构造成与目标容器中的开口配合。 尖端使用高电压电位将样品从针转移到插座。