公开(公告)号：US20130291662A1

公开(公告)日：2013-11-07

申请号：US13861237

申请日：2013-04-11

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kim L. JOHNSON ,  Jeremy JORDAN ,  Peter M. LEVINE ,  Mark James MILGREW

IPC: G01N33/00

CPC classification number: G01N27/4148 ,  C12Q1/6869 ,  G01J1/46 ,  G01N27/4143 ,  G01N27/4145 ,  G01N33/00 ,  G01R29/26 ,  H01L27/14609 ,  H01L27/14632 ,  H01L27/14643 ,  H01L29/66 ,  H01L2924/0002 ,  H04N5/374 ,  Y10T436/25875 ,  H01L2924/00

Abstract: The described embodiments may provide a chemical detection circuit that may comprise a plurality of first output circuits at a first side and a plurality of second output circuits at a second side of the chemical detection circuit. The chemical detection circuit may further comprise a plurality of tiles of pixels each placed between respective pairs of first and second output circuits. Each tile may include four quadrants of pixels. Each quadrant may have columns with designated first columns interleaved with second columns. Each first column may be coupled to a respective first output circuit in first and second quadrants, and to a respective second output circuit in third and fourth quadrants. Each second column may be coupled to a respective second output circuit in first and second quadrants, and to a respective first output circuit in third and fourth quadrants.

Abstract translation: 所描述的实施例可以提供化学检测电路，其可以包括在第一侧的多个第一输出电路和在化学检测电路的第二侧的多个第二输出电路。 化学检测电路还可以包括多个像素瓦片，每个瓷砖分别放置在相应的第一和第二输出电路对之间。 每个瓦片可以包括四个像素象限。 每个象限可以具有与第二列交错的指定的第一列的列。 每个第一列可以耦合到第一和第二象限中的相应的第一输出电路，以及耦合到第三和第四象限中的相应的第二输出电路。 每个第二列可以耦合到第一和第二象限中的相应的第二输出电路，以及耦合到第三和第四象限中的相应的第一输出电路。

公开(公告)号：US20150241387A1

公开(公告)日：2015-08-27

申请号：US14597507

申请日：2015-01-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kim L. JOHNSON ,  Jeremy JORDAN ,  Peter M. LEVINE ,  Mark James MILGREW

IPC: G01N27/414

Abstract: The described embodiments may provide a chemical detection circuit that may comprise a plurality of first output circuits at a first side and a plurality of second output circuits at a second side of the chemical detection circuit. The chemical detection circuit may further comprise a plurality of tiles of pixels each placed between respective pairs of first and second output circuits. Each tile may include four quadrants of pixels. Each quadrant may have columns with designated first columns interleaved with second columns. Each first column may be coupled to a respective first output circuit in first and second quadrants, and to a respective second output circuit in third and fourth quadrants. Each second column may be coupled to a respective second output circuit in first and second quadrants, and to a respective first output circuit in third and fourth quadrants.

Abstract translation: 所描述的实施例可以提供化学检测电路，其可以包括在第一侧的多个第一输出电路和在化学检测电路的第二侧的多个第二输出电路。 化学检测电路还可以包括多个像素瓦片，每个瓷砖分别放置在相应的第一和第二输出电路对之间。 每个瓦片可以包括四个像素象限。 每个象限可以具有与第二列交错的指定的第一列的列。 每个第一列可以耦合到第一和第二象限中的相应的第一输出电路，以及耦合到第三和第四象限中的相应的第二输出电路。 每个第二列可以耦合到第一和第二象限中的相应的第二输出电路，以及耦合到第三和第四象限中的相应的第一输出电路。

公开(公告)号：US20140361781A1

公开(公告)日：2014-12-11

申请号：US14465251

申请日：2014-08-21

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Peter M. LEVINE ,  Mark James MILGREW ,  Todd REARICK

IPC: G01N27/414

Abstract: One or more charge pumps may be used to amplify the output voltage from a chemically-sensitive pixel that comprises one or more transistors. A charge pump may include a number of track stage switches, a number of boost phase switches and a number of capacitors. The capacitors are in parallel during the track phase and in series during the boost phase, and the total capacitance is divided during the boost phase while the total charge remains fixed. Consequently, the output voltage is pushed up.

Abstract translation: 可以使用一个或多个电荷泵来放大来自包含一个或多个晶体管的化学敏感像素的输出电压。 电荷泵可以包括多个轨道平台开关，多个升压相位开关和多个电容器。 电容器在磁道相位期间并联并且在升压阶段期间串联，并且总电容在升压阶段被分压，而总电荷保持固定。 因此，输出电压被上推。

公开(公告)号：US20240201127A1

公开(公告)日：2024-06-20

申请号：US18530075

申请日：2023-12-05

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Kim L. JOHNSON ,  Jeremy JORDAN ,  Mark J. MILGREW ,  Peter M. LEVINE

IPC: G01N27/414 ,  C12Q1/6869 ,  G01J1/46 ,  G01N33/00 ,  G01R29/26 ,  H01L27/146 ,  H01L29/66 ,  H04N25/76

CPC classification number: G01N27/4148 ,  C12Q1/6869 ,  G01N27/4143 ,  G01N27/4145 ,  G01N33/00 ,  G01R29/26 ,  H01L27/14609 ,  H01L27/14632 ,  H01L29/66 ,  H04N25/76 ,  G01J1/46 ,  H01L27/14643 ,  H01L2924/0002 ,  Y10T436/25875

Abstract: The described semiconductor device can include a two-transistor pixel array. Each pixel in the two-transistor pixel array can include a chemical detection pixel comprising a chemically-sensitive transistor and a row-selection transistor connected between a current source and a chemically-sensitive transistor. The source of the chemically-sensitive transistor can be coupled to a column line, and the drain of the chemically-sensitive transistor can be coupled to the source of the row selection transistor. The gate of the row selection transistor can be couple to a row line. When a row line is activated, the row selection transistor can couple the chemically-sensitive transistor to the column line.

公开(公告)号：US20180224393A1

公开(公告)日：2018-08-09

申请号：US15943668

申请日：2018-04-02

Applicant: Life Technologies Corporation

Inventor： Kim L. JOHNSON ,  Jeremy JORDAN ,  Peter M. LEVINE ,  Mark James MILGREW

IPC: G01N27/414 ,  H04N5/374 ,  G01R29/26 ,  C12Q1/6869 ,  H01L29/66 ,  H01L27/146 ,  G01N33/00 ,  G01J1/46

Abstract: The described embodiments may provide a chemical detection circuit that may comprise a plurality of first output circuits at a first side and a plurality of second output circuits at a second side of the chemical detection circuit. The chemical detection circuit may further comprise a plurality of tiles of pixels each placed between respective pairs of first and second output circuits. Each tile may include four quadrants of pixels. Each quadrant may have columns with designated first columns interleaved with second columns. Each first column may be coupled to a respective first output circuit in first and second quadrants, and to a respective second output circuit in third and fourth quadrants. Each second column may be coupled to a respective second output circuit in first and second quadrants, and to a respective first output circuit in third and fourth quadrants.