MICROBIAL FERMENTATION FOR THE PRODUCTION OF TERPENES

    公开(公告)号:US20230013524A1

    公开(公告)日:2023-01-19

    申请号:US17823471

    申请日:2022-08-30

    Inventor: Michael Koepke

    Abstract: The invention provides a method for producing a terpene or a precursor thereof by microbial fermentation. Typically, the method involves culturing a recombinant bacterium in the presence of a gaseous substrate whereby the bacterium produces a terpene or a precursor thereof, such as mevalonic acid, isopentenyl pyrophosphate, dimethylallyl pyrophosphate, isoprene, geranyl pyrophosphate, farnesyl pyrophosphate, and/or farnesene. The bacterium may comprise one or more exogenous enzymes, such as enzymes in mevalonate, DXS, or terpene biosynthesis pathways.

    Microbial fermentation for the production of terpenes

    公开(公告)号:US11459589B2

    公开(公告)日:2022-10-04

    申请号:US17095064

    申请日:2020-11-11

    Inventor: Michael Koepke

    Abstract: The invention provides a method for producing a terpene or a precursor thereof by microbial fermentation. Typically, the method involves culturing a recombinant bacterium in the presence of a gaseous substrate whereby the bacterium produces a terpene or a precursor thereof, such as mevalonic acid, isopentenyl pyrophosphate, dimethylallyl pyrophosphate, isoprene, geranyl pyrophosphate, farnesyl pyrophosphate, and/or farnesene. The bacterium may comprise one or more exogenous enzymes, such as enzymes in mevalonate, DXS, or terpene biosynthesis pathways.

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