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1.发明授权
公开(公告)号：US5677123A
公开(公告)日：1997-10-14
申请号：US487638
申请日：1995-06-07
CPC分类号： C12Q1/04 , C12Q1/689 , G01N2333/16 , G01N2333/30
摘要： Novel mycoplasmas are described which are prominent in patients who are thought to be suffering from AIDS. Devices are also provided for the in vitro detection of mycoplasmas in a biological fluid by means of a reagent which is specific for the mycoplasma group without being specific for particular species within said group. Devices for testing mycoplasma sensitivity to antibiotics are also described.
摘要翻译： 描述了在被认为患有艾滋病的患者中突出的新型支原体。 还提供了用于通过对支原体组特异性的试剂体外检测生物流体中支原体的装置，而不对所述组中的特定物种具有特异性。 还描述了测试支原体对抗生素敏感性的装置。
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2.发明授权
公开(公告)号：US5688646A
公开(公告)日：1997-11-18
申请号：US480055
申请日：1995-06-07
CPC分类号： C12Q1/04 , C12Q1/689 , G01N2333/16 , G01N2333/30
摘要： Novel mycoplasmas are described which are prominent in patients who are thought to be suffering from AIDS. Devices are also provided for the in vitro detection of mycoplasmas in biological fluid by means of a reagent which is specific for the mycoplasma group without being specific for particular species within said group. Devices for testing mycoplasma sensitivity to antibiotics are also described.
摘要翻译： 描述了在被认为患有艾滋病的患者中突出的新型支原体。 还提供了用于通过对支原体组特异的试剂体外检测生物流体中的支原体的装置，而不对所述组内的特定物种具有特异性。 还描述了测试支原体对抗生素敏感性的装置。
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公开(公告)号：US07341731B2
公开(公告)日：2008-03-11
申请号：US10180460
申请日：2002-06-27
申请人： Luc Montagnier , Solange Chamaret , Denise Guetard , Marc Alizon , François Clavel , Mireille Guyader , Pierre Sonigo , Françoise Brun-Vezinet , Marianne Rey , Christine Rouzioux , Christine Katlama
发明人： Luc Montagnier , Solange Chamaret , Denise Guetard , Marc Alizon , François Clavel , Mireille Guyader , Pierre Sonigo , Françoise Brun-Vezinet , Marianne Rey , Christine Rouzioux , Christine Katlama
IPC分类号： A61K39/21
CPC分类号： C07K7/06 , A61K38/00 , A61K39/00 , C07K14/005 , C12N7/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , C12Q1/703 , G01N33/56988 , G01N2333/162 , G01N2469/20
摘要： The invention relates to a composition comprising at least one antigen, wherein the antigen is a protein or glycoprotein of a HIV-2 virus, wherein the HIV-2 virus has infectious properties with respect to human T4 lymphocytes and the essential morphological or immunological property of at least one of the retroviruses deposited at the CNCM under No. I-502, I-532, I-642, and I-643. It also relates to a process for the production of HIV-2 retrovirus antigens by lysing cells infected with the virus or lysing purified virus and recovering the antigens.
摘要翻译： 本发明涉及包含至少一种抗原的组合物，其中所述抗原是HIV-2病毒的蛋白质或糖蛋白，其中所述HIV-2病毒相对于人T4淋巴细胞具有感染性质，以及所述HIV-2病毒的基本形态学或免疫学性质 至少有一种在CNCM下存放在I-502，I-532，I-642和I-643下的逆转录病毒。 它还涉及通过裂解感染病毒的细胞或裂解纯化的病毒并回收抗原来生产HIV-2逆转录病毒抗原的方法。
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4.发明授权Human immunodeficiency virus type 2 (HIV-2) env polypeptide and diagnostic assays 失效人类免疫缺陷病毒2型（HIV-2）env多肽和诊断测定公开(公告)号：US06979535B2
公开(公告)日：2005-12-27
申请号：US10133357
申请日：2002-04-29
申请人： Marc Alizon , Luc Montagnier , Denise Guetard , Francois Clavel , Pierre Sonigo , Mireille Guyader
发明人： Marc Alizon , Luc Montagnier , Denise Guetard , Francois Clavel , Pierre Sonigo , Mireille Guyader
CPC分类号： C07K7/06 , A61K38/00 , A61K39/00 , C07K14/005 , C12N7/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , C12Q1/703 , G01N33/56988 , G01N2333/162 , G01N2469/20
摘要： A method for diagnosing an HIV-2 (LAV-II) infection and a kit containing reagents for the same is disclosed. These reagents include cDNA probes which are capable of hybridizing to at least a portion of the genome of HIV-2. In one embodiment, the DNA probes are capable of hybridizing to the entire genome of HIV-2. These reagents also include polypeptides encoded by some of these DNA sequences.
摘要翻译： 公开了用于诊断HIV-2（LAV-II）感染的方法和用于其的试剂盒。 这些试剂包括能够与HIV-2的至少一部分基因组杂交的cDNA探针。 在一个实施方案中，DNA探针能够与HIV-2的整个基因组杂交。 这些试剂还包括由这些DNA序列中的一些编码的多肽。
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5.发明授权In vitro diagnostic methods and kits for the detection of HIV-2-specific antibodies 失效用于检测HIV-2特异性抗体的体外诊断方法和试剂盒公开(公告)号：US06265149B1
公开(公告)日：2001-07-24
申请号：US08470491
申请日：1995-06-06
申请人： Luc Montagnier , Solange Chamaret , Denise Guetard , Marc Alizon , François Clavel , Mireille Guyader , Pierre Sonigo , Françoise Brun-Vezinet , Marianne Rey , Christine Rouzioux , Christine Katlama
发明人： Luc Montagnier , Solange Chamaret , Denise Guetard , Marc Alizon , François Clavel , Mireille Guyader , Pierre Sonigo , Françoise Brun-Vezinet , Marianne Rey , Christine Rouzioux , Christine Katlama
IPC分类号： C12Q170
CPC分类号： C07K7/06 , A61K38/00 , A61K39/00 , C07K14/005 , C12N7/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , C12Q1/703 , G01N33/56988 , G01N2333/162 , G01N2469/20
摘要： The claimed invention is directed toward in vitro methods for the detection of human immunodeficiency virus type 2 (HIV-2) antibodies employing polypeptide fragments of HIV-2 Gag.
摘要翻译： 所要求保护的发明涉及使用HIV-2Gag的多肽片段检测使用HIV-2抗体的人类免疫缺陷病毒的体外方法。
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6.发明授权Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes 失效能够引起艾滋病的逆转录病毒，从该逆转录病毒获得的抗原和相应的抗体及其用于诊断目的的应用
公开(公告)号：US5030718A
公开(公告)日：1991-07-09
申请号：US462984
申请日：1990-01-10
CPC分类号： C07K14/005 , C07K7/06 , C12N7/00 , C12Q1/703 , G01N33/56988 , A61K38/00 , A61K39/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , G01N2333/162 , G01N2469/20 , Y10S435/974 , Y10S435/975 , Y10S530/826 , Y10S930/221
摘要： The invention relates to a new variety of retroviruses designated Human Immunodeficiency virus Type II, HIV-II, samples of which have been deposited at CNCM as I-502 and I-532. It also concerns purified forms of the antigens which can be obtained from this virus, in particular from the gp 36 and gp 130-140 proteins. These various antigens are useful in medical diagnosis and kits, in particular by being placed in contact with serum of the patient to be diagnosed. Lastly, the invention relates to immunizing compositions, in particular containing at least one of glycoproteins gp 36 and gp 130-140.
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7.发明授权公开(公告)号：US07157225B2
公开(公告)日：2007-01-02
申请号：US10026741
申请日：2001-12-27
申请人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques H. M. Cohen
发明人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques H. M. Cohen
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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8.发明授权公开(公告)号：US06399294B1
公开(公告)日：2002-06-04
申请号：US08817441
申请日：1997-07-11
申请人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques Cohen
发明人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon De Saint-Martin , Jacques Cohen
IPC分类号： C12Q170
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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9.发明授权Methods for the preparation of human immunodeficiency virus type 2 (HIV-2) and antigens encoped thereby 失效制备人类免疫缺陷病毒2型（HIV-2）的方法和由此编码的抗原
公开(公告)号：US06037165A
公开(公告)日：2000-03-14
申请号：US470487
申请日：1995-06-06
申请人： Luc Montagnier , Solange Chamaret , Denise Guetard , Marc Alizon , Fran.cedilla.ois Clavel , Mireille Guyader , Pierre Sonigo , Fran.cedilla.oise Brun-Vezinet , Marianne Rey , Christine Rouzioux , Christine Katlama
发明人： Luc Montagnier , Solange Chamaret , Denise Guetard , Marc Alizon , Fran.cedilla.ois Clavel , Mireille Guyader , Pierre Sonigo , Fran.cedilla.oise Brun-Vezinet , Marianne Rey , Christine Rouzioux , Christine Katlama
IPC分类号： A61K38/00 , A61K39/00 , A61K39/21 , C07H21/02 , C07K7/06 , C07K14/16 , C12N7/00 , C12Q1/68 , C12Q1/70 , G01N33/53 , G01N33/569
CPC分类号： C07K7/06 , C07K14/005 , C12N7/00 , C12Q1/703 , G01N33/56988 , A61K38/00 , A61K39/00 , C12N2740/16021 , C12N2740/16122 , C12N2740/16222 , G01N2333/162 , G01N2469/20
摘要： Methods for producing the newly discovered HIV-2 retrovirus and its antigens are provided. The antigens are obtained from various HIV-2 retroviruses. The antigen compositions comprise a lysate of an HIV-2 retrovirus, a protein of an HIV-2 retrovirus, or a glycoprotein of an HIV-2 retrovirus. Specifically, the antigen composition can comprise p12, p16, p26, gp32, gp42, and gp140.
摘要翻译： 提供了新发现的HIV-2逆转录病毒及其抗原的制备方法。 抗原是从各种HIV-2逆转录病毒获得的。 抗原组合物包含HIV-2逆转录病毒的裂解物，HIV-2逆转录病毒的蛋白质或HIV-2逆转录病毒的糖蛋白。 具体地，抗原组合物可以包含p12，p16，p26，gp32，gp42和gp140。
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10.发明授权Nucleotide sequences of HIV-1 group (or subgroup) O retroviral antigens 失效HIV-1组（或亚组）O逆转录病毒抗原的核苷酸序列公开(公告)号：US08236324B2
公开(公告)日：2012-08-07
申请号：US11591678
申请日：2006-11-02
申请人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon de Saint-Martin , Jacques Cohen
发明人： Pierre Charneau , François Clavel , Andrew Borman , Caroline Quillent , Denise Guetard , Luc Montagnier , Jacqueline Donjon de Saint-Martin , Jacques Cohen
IPC分类号： A61K39/21
CPC分类号： C07K14/005 , C12N2740/16021 , C12N2740/16022 , C12N2740/16043 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , G01N33/56988 , Y10S435/975
摘要： An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognized by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.
摘要翻译： HIV-1型（或亚型）O逆转录病毒蛋白，或包含至少一部分所述蛋白质的天然或合成多肽或肽，其能够被从HIV-1感染引起的血清分离的抗体识别 O型VAU菌株或HIV-1型（或亚型）O DUR菌株。
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