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公开(公告)号：US20140276411A1
公开(公告)日：2014-09-18
申请号：US13826483
申请日：2013-03-14
申请人： MEDRAD, INC.
IPC分类号： A61M5/145
CPC分类号： A61M5/1409 , A61B5/055 , A61B6/032 , A61B6/481 , A61B6/504 , A61M5/007 , A61M5/1452 , A61M5/14526 , A61M5/14546 , A61M5/14566 , A61M5/2053 , A61M5/31568 , A61M39/24 , A61M2005/1403 , A61M2005/14513 , A61M2205/3306 , A61M2205/3317 , A61M2205/3375
摘要： A fluid delivery system includes a pressurizing mechanism. The pressurizing mechanism includes: a substantially cylindrical body having a movable member positioned therein that divides the body into a first chamber and a second chamber; a plunger rod connected to a first side of the movable member and extending through a substantially closed first end of the body; and an elongated member connected to a second side of the movable member and extending through a substantially closed second end of the body. The plunger rod configured to operatively engage a fluid container. Fluid is dispensed from the fluid container by forming a vacuum within at least the first chamber by moving the movable member toward the second end of the body, allowing atmospheric pressure to enter the second chamber, and actuating the pressurizing mechanism to cause the moving member to move towards the first end of the body.
摘要翻译： 流体输送系统包括加压机构。 加压机构包括：基本上圆柱形的主体，其具有定位在其中的可动构件，其将主体分成第一室和第二室; 柱塞杆，其连接到所述可移动部件的第一侧并延伸穿过所述主体的基本封闭的第一端; 以及细长构件，其连接到所述可移动构件的第二侧并延伸穿过所述主体的基本封闭的第二端。 柱塞杆构造成可操作地接合流体容器。 通过将活动件向身体的第二端移动，使至少第一腔室内的真空成为至少第一腔室内的真空，允许大气压力进入第二腔室，并且致动加压机构，使移动构件 向身体的第一端移动。
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公开(公告)号：US20140261758A1
公开(公告)日：2014-09-18
申请号：US13835522
申请日：2013-03-15
申请人： MEDRAD, INC.
CPC分类号： A61M39/10 , A61M5/007 , A61M5/1407 , A61M5/1408 , A61M5/14566 , A61M5/16827 , A61M5/348 , A61M2005/3246 , A61M2039/1016 , A61M2039/1027 , Y10T137/598
摘要： A connector assembly for a fluid delivery system includes a conical body defining an interior cavity and a discharge outlet, the discharge outlet defining an internal passage in fluid communication with the interior cavity; and a connector removably attached to the discharge outlet. The connector includes a central body configured to be at least partially positioned within the internal passage of the discharge outlet, and an annular connector portion connected to the central body and configured to releasably engage an exterior of the discharge outlet, the central body defining an internal channel within the central body that is in fluid communication with the interior cavity of the conical body when the connector is attached to the discharge outlet.
摘要翻译： 用于流体输送系统的连接器组件包括限定内腔和排出口的圆锥体，排出口限定与内腔流体连通的内部通道; 以及可移除地附接到排出口的连接器。 连接器包括中心体，其构造成至少部分地定位在排出口的内部通道内;以及环形连接器部分，其连接到中心体并构造成可释放地接合排出口的外部，中心体限定内部 通道在中心体内与连接器连接到排出口时与锥形体的内腔流体连通。
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公开(公告)号：US09101713B2
公开(公告)日：2015-08-11
申请号：US13797959
申请日：2013-03-12
申请人： MEDRAD, INC.
发明人： Kevin P. Cowan , Barry L. Tucker
CPC分类号： A61M5/3148 , A61M5/007 , A61M5/14526 , A61M5/16877 , A61M5/2053 , A61M5/3137 , A61M5/31515 , A61M5/36 , A61M5/48 , A61M2005/3123 , A61M2005/3128 , A61M2005/3139 , A61M2202/0007
摘要： Various syringe systems are disclosed. One such syringe system may include a body having a hollow lumen and a distal end, a vacuum chamber disposed within the hollow lumen of the syringe body, a first plunger connected to a distal portion of the vacuum chamber, the first plunger forming a first seal against an inner surface of the syringe body and defining a fluid delivery volume between the first plunger and the distal end of the syringe body, a second plunger disposed within the vacuum chamber, the second plunger forming a second seal against an inner surface of the vacuum chamber and defining a proximal and distal volume compartments within the vacuum chamber, and a piston affixed to the second plunger, the piston configured to move the second plunger within the vacuum chamber, thereby altering a volume of the proximal volume compartment and a volume of the distal volume compartment.
摘要翻译： 公开了各种注射器系统。 一个这样的注射器系统可以包括具有中空内腔和远端的本体，设置在注射器主体的中空腔内的真空室，连接到真空室的远端部分的第一柱塞，第一柱塞形成第一密封件 抵靠注射器主体的内表面并且在第一柱塞和注射器主体的远端之间限定流体输送体积，设置在真空室内的第二柱塞，第二柱塞形成抵靠真空内表面的第二密封 并且限定真空室内的近端和远端容积隔室，以及固定到第二柱塞的活塞，活塞构造成使第二柱塞在真空室内移动，由此改变近端容积隔室的体积和 远端容积室。
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公开(公告)号：US20140163475A1
公开(公告)日：2014-06-12
申请号：US13845713
申请日：2013-03-18
申请人： MEDRAD, INC.
CPC分类号： A61J1/1443 , A61J1/1456 , A61J1/1475 , A61M5/142 , A61M5/1723 , A61M5/3145 , A61M31/005 , B01L3/502 , B01L2300/044 , B01L2300/0681 , G06F19/3468
摘要： A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
摘要翻译： 用于处理细胞（和/或其它注射组分）的系统包括适于可滑动地定位在容器内的容器和柱塞。 该系统包括至少一个入口，流体可以通过该入口进入系统和至少一个流出物端口，流出物可通过该至少一个出口端口离开系统。 柱塞部分形成与容器的内壁的密封接合，使得柱塞的向后运动适于经由入口将流体引入系统，并且柱塞的向前运动适于通过流出物强制流出系统的流出物 港口。
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公开(公告)号：US09486573B2
公开(公告)日：2016-11-08
申请号：US13826483
申请日：2013-03-14
申请人： Medrad, Inc.
CPC分类号： A61M5/1409 , A61B5/055 , A61B6/032 , A61B6/481 , A61B6/504 , A61M5/007 , A61M5/1452 , A61M5/14526 , A61M5/14546 , A61M5/14566 , A61M5/2053 , A61M5/31568 , A61M39/24 , A61M2005/1403 , A61M2005/14513 , A61M2205/3306 , A61M2205/3317 , A61M2205/3375
摘要： A fluid delivery system includes a pressurizing mechanism. The pressurizing mechanism includes: a substantially cylindrical body having a movable member positioned therein that divides the body into a first chamber and a second chamber; a plunger rod connected to a first side of the movable member and extending through a substantially closed first end of the body; and an elongated member connected to a second side of the movable member and extending through a substantially closed second end of the body. The plunger rod configured to operatively engage a fluid container. Fluid is dispensed from the fluid container by forming a vacuum within at least the first chamber by moving the movable member toward the second end of the body, allowing atmospheric pressure to enter the second chamber, and actuating the pressurizing mechanism to cause the moving member to move towards the first end of the body.
摘要翻译： 流体输送系统包括加压机构。 加压机构包括：基本上圆柱形的主体，其具有定位在其中的可动构件，其将主体分成第一室和第二室; 柱塞杆，其连接到所述可移动部件的第一侧并延伸穿过所述主体的基本封闭的第一端; 以及细长构件，其连接到所述可移动构件的第二侧并延伸穿过所述主体的基本封闭的第二端。 柱塞杆构造成可操作地接合流体容器。 通过将活动件向身体的第二端移动，使至少第一腔室内的真空成为至少第一腔室内的真空，允许大气压力进入第二腔室，并且致动加压机构，使移动构件 向身体的第一端移动。
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公开(公告)号：US09408981B2
公开(公告)日：2016-08-09
申请号：US13792158
申请日：2013-03-10
申请人： MEDRAD, INC.
发明人： Kevin P. Cowan
CPC分类号： A61M5/007 , A61M5/1785 , A61M5/19 , A61M5/20 , A61M5/3137 , A61M5/31513 , A61M5/31561 , A61M5/31563 , A61M5/31583 , A61M5/31596 , A61M2005/1787 , A61M2005/3128 , A61M2005/3139 , A61M2005/31598 , A61M2205/50 , A61M2205/505 , A61M2205/52
摘要： Adjustable volume syringes and systems are disclosed. An adjustable volume syringe includes a delivery syringe barrel, a reservoir syringe barrel positioned at least partially within the delivery syringe barrel, and a reservoir plunger positioned at least partially within the reservoir syringe barrel. The delivery syringe barrel is configured to contain a first amount of a fluid. The reservoir syringe barrel is configured to contain a second amount of the fluid. A system includes the adjustable volume syringe, a dispensing module in communication with the syringe, and a processor in communication with the dispensing module. The processor may be configured to determine an administration amount of the fluid in the adjustable volume syringe, and transmit signals causing the dispensing module to adjust the volume of fluid in the syringe to the administration amount and deliver the administration amount by moving the reservoir syringe barrel with respect to the delivery syringe barrel.
摘要翻译： 公开了可调节的体积注射器和系统。 可调节体积的注射器包括输送注射器筒，至少部分地定位在递送注射器筒内的储存器注射器筒，以及至少部分地位于储存器注射器筒内的储存器柱塞。 输送注射器筒构造成容纳第一量的流体。 储存器注射器筒构造成容纳第二量的流体。 系统包括可调节体积注射器，与注射器连通的分配模块以及与分配模块连通的处理器。 处理器可以被配置为确定可调节体积注射器中的流体的管理量，并且传输使得分配模块将注射器中的流体的体积调节到管理量的信号，并且通过移动储存器注射器筒 相对于输送注射器筒。
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公开(公告)号：US09174003B2
公开(公告)日：2015-11-03
申请号：US13792155
申请日：2013-03-10
申请人： MEDRAD, INC.
发明人： Kevin P. Cowan , Edward J. Rhinehart , Mark Trocki
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/315 , A61M5/31511 , A61M5/31515 , A61M5/5066 , A61M2005/31521
摘要： A syringe system and components thereof are disclosed. The system may include a syringe body having a hollow lumen, a proximal open end, and a distal end. The syringe body may be configured to house a fluid therein. The syringe system may further include a plunger positioned in the hollow lumen of the syringe body, forming a seal with an inner wall of the syringe body. The plunger may include a removable piston having a shaft extending from the distal end towards the proximal open end, a stopper removably connected to a distal portion of the shaft, and at least one coupler attached to the distal portion of the shaft. The stopper may be configured to slidably move within the hollow lumen to facilitate movement of the fluid within the syringe body. The coupler may be configured to facilitate removal and attachment of the stopper from the piston.
摘要翻译： 公开了一种注射器系统及其部件。 该系统可以包括具有中空管腔，近端开口端和远端的注射器主体。 注射器主体可构造成在其中容纳流体。 注射器系统还可以包括定位在注射器主体的中空内腔中的柱塞，与注射器主体的内壁形成密封。 柱塞可以包括可移除的活塞，其具有从远端朝向近端开口端延伸的轴，可拆卸地连接到轴的远侧部分的止动件和附接到轴的远端部分的至少一个联接器。 止动器可以构造成在空腔内可滑动地移动，以便于流体在注射器主体内的运动。 联接器可以被配置为便于将止动件从活塞移除和附接。
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公开(公告)号：US09114215B2
公开(公告)日：2015-08-25
申请号：US13802372
申请日：2013-03-13
申请人： MEDRAD, INC.
CPC分类号： A61M5/31513 , A61M5/007 , A61M5/19 , A61M5/31596 , A61M2005/1404 , A61M2005/1787 , A61M2005/3103 , A61M2005/3128 , A61M2005/3132 , A61M2005/31598
摘要： Various syringe systems are disclosed. One illustrative syringe system may include a syringe body having a hollow lumen and a distal end. The syringe body may be configured to house a plurality of fluids therein. A first plunger may be positioned in the hollow lumen of the syringe body, forming a first seal with an inner wall of the syringe body, and forming a first compartment between the first plunger and the distal end of the syringe. A second plunger may be positioned proximal to the first plunger in the hollow lumen of the syringe body, forming a second seal with the inner wall of the syringe body, and forming a second compartment between the first plunger and the second plunger. A plurality of recesses may be disposed about the inner wall of the syringe body near the distal end of the syringe body.
摘要翻译： 公开了各种注射器系统。 一个说明性的注射器系统可以包括具有中空内腔和远端的注射器主体。 注射器主体可构造成在其中容纳多个流体。 第一柱塞可以位于注射器主体的中空腔中，与注射器主体的内壁形成第一密封，并且在第一柱塞和注射器的远端之间形成第一隔室。 第二柱塞可以位于注射器主体的中空内腔中的第一柱塞的近侧，与注射器主体的内壁形成第二密封，并且在第一柱塞和第二柱塞之间形成第二隔室。 可以在注射器主体的远端附近围绕注射器本体的内壁设置多个凹部。
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9.发明申请公开(公告)号：US20140046295A1
公开(公告)日：2014-02-13
申请号：US13971095
申请日：2013-08-20
申请人： Medrad, Inc.
发明人： Arthur E. Uber, III , Mark Trocki , Marc A. Mabie , Larry McCutchan , L. George Siddoway , Kevin P. Cowan , Lisa M. Coates , John F. Kalafut , Aaron Hughes , David M. Griffiths , Peter Twichell , Julie Gulick , Frederick W. Trombley, III
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61M5/007 , A61M5/16827 , A61M5/1785 , A61M2005/1402 , A61M2202/0225 , A61M2202/049 , A61M2206/11 , A61M2206/18 , Y10T137/0318
摘要： A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.
摘要翻译： 公开了一种危险流体输送容器和危险流体输送系统。 危险流体输送容器包括封闭至少部分屏蔽的外壳的壳体。 第一和第二流体通道元件设置在壳体内，第一流体路径元件和第二流体路径元件流体耦合在一起。 可以提供泵单元，用于将流体从第一和第二流体路径元件任选地分配到第三流体路径元件中。 此外，公开了用于引燃危险流体输送容器和减轻层流注射团块扩散的方法。 此外，公开了一种用于注射器或其他容器的放射性流体输送容器。 放射性流体输送容器允许注射器或容器在注射过程中使用而不从容器中取出。
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