公开(公告)号：US11980463B2

公开(公告)日：2024-05-14

申请号：US16534131

申请日：2019-08-07

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Bahar Reghabi ,  James L. Henke ,  Wayne A. Morgan ,  Gopikrishnan Soundararajan ,  David Y. Choy ,  Peter Schultz ,  Udo Hoss

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  A61M5/172 ,  G01N27/327

CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/4839 ,  G01N27/327 ,  G01N27/3274 ,  A61B2560/0223 ,  A61M5/1723 ,  A61M2230/201

Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic—cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

公开(公告)号：US09976978B2

公开(公告)日：2018-05-22

申请号：US15640888

申请日：2017-07-03

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC: A61B5/00 ,  G01N27/403 ,  A61B5/145 ,  G01N27/327 ,  G01N27/416 ,  A61B5/1473 ,  C12Q1/00

CPC classification number: G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

Abstract: A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

公开(公告)号：US09360447B2

公开(公告)日：2016-06-07

申请号：US13964591

申请日：2013-08-12

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC: A61B5/00 ,  G01N27/403 ,  A61B5/145 ,  G01N27/327 ,  G01N27/416 ,  A61B5/1473

CPC classification number: G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

Abstract: A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

公开(公告)号：US11998327B2

公开(公告)日：2024-06-04

申请号：US16533131

申请日：2019-08-06

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Wayne A. Morgan

IPC: A61B5/1473 ,  A61B5/00 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1495

CPC classification number: A61B5/1473 ,  A61B5/0002 ,  A61B5/053 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/6849 ,  A61B5/7203 ,  A61B5/7225 ,  A61B2560/0214 ,  A61B2560/0223 ,  A61B2562/0214 ,  A61B2562/166 ,  A61B2562/227

Abstract: The double layer capacitance of a working electrode of a sensor may be measured with minimal disruption to the sensor equilibrium by open circuiting the working electrode and measuring the voltage drift on a periodic, or as-needed, basis. The values of the double layer capacitance may be monitored over time to determine, e.g., sensor age and condition.

公开(公告)号：US10426389B2

公开(公告)日：2019-10-01

申请号：US15140961

申请日：2016-04-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Wayne A. Morgan

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/145 ,  A61B5/1486 ,  A61B5/1473 ,  A61B5/053

Abstract: The double layer capacitance of a working electrode of a sensor may be measured with minimal disruption to the sensor equilibrium by open circuiting the working electrode and measuring the voltage drift on a periodic, or as-needed, basis. The values of the double layer capacitance may be monitored over time to determine, e.g., sensor age and condition.

公开(公告)号：US10288578B2

公开(公告)日：2019-05-14

申请号：US15851359

申请日：2017-12-21

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC: G01N27/403 ,  A61B5/145 ,  G01N27/327 ,  G01N27/416 ,  A61B5/1473 ,  C12Q1/00

Abstract: A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

公开(公告)号：US20130331676A1

公开(公告)日：2013-12-12

申请号：US13778611

申请日：2013-02-27

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Wayne A. Morgan ,  Paris Chen ,  Rajiv Shah

IPC: A61B5/145

CPC classification number: A61B5/1495 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/6852 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7225 ,  A61B5/7242 ,  A61B5/746 ,  A61B2562/0214 ,  A61B2562/04 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/1582 ,  A61M5/1723 ,  A61M2005/1726 ,  G01N27/026 ,  G01N27/028 ,  G01N27/416 ,  G01N27/4163 ,  G01N33/49 ,  G01N33/66 ,  G01N33/96 ,  G01R35/00 ,  G01R35/005

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US10420496B2

公开(公告)日：2019-09-24

申请号：US15366247

申请日：2016-12-01

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Bahar Reghabi ,  James L. Henke ,  Wayne A. Morgan ,  Gopikrishnan Soundararajan ,  David Y. Choy ,  Peter Schultz ,  Udo Hoss

IPC: A61B5/00 ,  A61B5/1495 ,  G01N27/327 ,  A61B5/145 ,  A61B5/1486 ,  A61M5/172

Abstract: A blood glucose sensing system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes stabilization circuitry. The stabilization circuitry causes a first voltage to be applied to one of the electrodes for a first timeframe and causes a second voltage to be applied to one of the electrodes for a second timeframe. The stabilization circuitry repeats the application of the first voltage and the second voltage to continue the anodic-cathodic cycle. The sensor electronics device may include a power supply, a regulator, and a voltage application device, where the voltage application device receives a regulated voltage from the regulator, applies a first voltage to an electrode for the first timeframe, and applies a second voltage to an electrode for the second timeframe.

公开(公告)号：US20140046154A1

公开(公告)日：2014-02-13

申请号：US14055155

申请日：2013-10-16

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Wayne A. Morgan ,  David Y. Choy ,  James L. Henke ,  Bahar Reghabi ,  Gopikrishnan Soundararajan ,  Peter Schultz ,  Udo Hoss

IPC: G01N27/403 ,  A61B5/1473

CPC classification number: G01N27/403 ,  A61B5/14532 ,  A61B5/1473 ,  A61B2560/0223 ,  A61B2562/02 ,  C12Q1/006 ,  G01N27/327 ,  G01N27/416

Abstract: A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.

公开(公告)号：US09970893B2

公开(公告)日：2018-05-15

申请号：US15141021

申请日：2016-04-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Wayne A. Morgan

IPC: G01N27/22 ,  G01N33/49 ,  G01R17/00 ,  G01R19/00 ,  G01N33/487 ,  A61B5/145 ,  A61B5/1473

CPC classification number: G01N27/22 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/7221 ,  G01N33/48707 ,  G01N33/49 ,  G01R17/00 ,  G01R19/0084

Abstract: The double layer capacitance of a working electrode of a sensor may be measured with minimal disruption to the sensor equilibrium by open circuiting the working electrode and measuring the voltage drift on a periodic, or as-needed, basis. The values of the double layer capacitance may be monitored over time to determine, e.g., sensor age and condition.