专利检索 ap:("Marc Adler" OR "Stefan Baeurle" OR "Judi Bryant" OR "Ming Chen" OR "Yuo-Ling Chou" OR "Paul Hrvatin" OR "Seock-Kyu Khim" OR "Monica Kochanny" OR "Wheeseong Lee" OR "Michael Mamounas" OR "Janet Meurer Ogden" OR "Gary Bruce Phillips" OR "Victor Selchau" OR "Christopher West" OR "Bin Ye" OR "Shendong Yuan" OR "Martin Krueger") AND inv:"Stefan Baeurle" 第 1 页

1.

发明申请
DIHYDROPYRIDINE DERIVATIVES AS USEFUL AS PROTEIN KINASE INHIBITORS 有权
标题翻译：作为蛋白激酶抑制剂有用的二氢吡啶衍生物

公开(公告)号：US20080176833A1

公开(公告)日：2008-07-24

申请号：US11955777

申请日：2007-12-13

申请人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger

发明人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger

IPC分类号： A61K31/55 , C07D213/02 , A61K31/4427 , C07D455/02 , A61K31/4375 , C07D295/00 , A61K31/5377 , A61P35/00 , C07D239/24 , A61K31/506 , C07D221/00 , A61K31/496 , C07D223/02

CPC分类号： C07D401/04 , C07D211/90 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/14 , C07D471/04

摘要： This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.

摘要翻译： 本发明提供具有蛋白酪氨酸激酶抑制活性的新颖的具有蛋白酪氨酸激酶抑制活性的二氢吡啶衍生物，其制备方法及其用于治疗c-Met介导的疾病或c-Met介导的病症的用途。

2.

发明授权
Dihydropyridine derivatives as useful as protein kinase inhibitors 有权
标题翻译：二氢吡啶衍生物可用作蛋白激酶抑制剂

公开(公告)号：US08198456B2

公开(公告)日：2012-06-12

申请号：US11955777

申请日：2007-12-13

申请人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger

发明人： Marc Adler , Stefan Baeurle , Judi Bryant , Ming Chen , Yuo-Ling Chou , Paul Hrvatin , Seock-Kyu Khim , Monica Kochanny , Wheeseong Lee , Michael Mamounas , Janet Meurer Ogden , Gary Bruce Phillips , Victor Selchau , Christopher West , Bin Ye , Shendong Yuan , Martin Krueger

IPC分类号： C07D401/04

CPC分类号： C07D401/04 , C07D211/90 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/14 , C07D471/04

摘要： This invention provides novel dihydropyridine derivatives of the formula I having protein tyrosine kinase inhibitory activity, to process for the manufacture thereof and to the use thereof for the treatment of c-Met-mediated diseases or c-Met-mediated conditions.

摘要翻译： 本发明提供具有蛋白酪氨酸激酶抑制活性的新颖的具有蛋白酪氨酸激酶抑制活性的二氢吡啶衍生物，其制备方法及其用于治疗c-Met介导的疾病或c-Met介导的病症的用途。

3.

发明申请
Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 失效
标题翻译：四氢萘衍生物，其生产方法及其作为抗炎剂的用途

公开(公告)号：US20050209324A1

公开(公告)日：2005-09-22

申请号：US10961406

申请日：2004-10-12

申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa

发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa

IPC分类号： A61K31/135 , A61K31/195 , A61K31/277

CPC分类号： C07D209/34 , C07D213/74 , C07D215/04 , C07D215/227 , C07D215/38 , C07D215/60 , C07D217/24 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/64 , C07D307/88 , C07D405/12 , C07D471/04

摘要： The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.

摘要翻译： 本发明涉及四氢萘衍生物，其制备方法及其作为抗炎剂的用途。

4.

发明申请
Rearranged pentanols, a process for their production and their use as anti-inflammatory agents 失效
标题翻译：重排戊醇，其生产过程及其作为抗炎剂的用途

公开(公告)号：US20050131226A1

公开(公告)日：2005-06-16

申请号：US10960757

申请日：2004-10-08

申请人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa

发明人： Hartmut Rehwinkel , Stefan Baeurle , Markus Berger , Norbert Schmees , Heike Schaecke , Konrad Krolikiewicz , Anne Mengel , Duy Nguyen , Stefan Jaroch , Werner Skuballa

IPC分类号： A61P29/00 , C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D277/68 , C07D311/76 , C07D471/02 , C07D498/02

CPC分类号： C07D209/46 , C07D215/38 , C07D231/56 , C07D237/32 , C07D239/74 , C07D311/76

摘要： The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents.

摘要翻译： 本发明涉及式I化合物，其制备方法及其作为抗炎剂的用途。

5.

发明申请
Non-steroidal progesterone receptor modulators 审中-公开
标题翻译：非甾体孕激素受体调节剂

公开(公告)号：US20090270381A1

公开(公告)日：2009-10-29

申请号：US12333789

申请日：2008-12-12

申请人： Wolfgang SCHWEDE , Thomas Andrew Kirkland , Carsten Moeller , Stefan Baeurle , Ralf Wyrwa , Andrea Rotgeri

发明人： Wolfgang SCHWEDE , Thomas Andrew Kirkland , Carsten Moeller , Stefan Baeurle , Ralf Wyrwa , Andrea Rotgeri

IPC分类号： A61K31/277 , C07C255/50 , C07D265/02 , C07D413/06 , A61K31/536 , A61P15/00

CPC分类号： C07D317/30 , C07C255/60 , C07C317/46 , C07C2601/08 , C07C2601/14 , C07D211/22 , C07D211/32 , C07D211/34 , C07D213/30 , C07D213/56 , C07D261/20 , C07D265/02 , C07D295/13 , C07D295/155 , C07D295/18 , C07D295/192 , C07D309/06 , C07D317/20 , C07D333/16 , C07D335/02 , C07D401/06 , C07D401/10 , C07D405/06 , C07D405/10 , C07D407/06 , C07D407/10 , C07D409/06 , C07D409/10 , C07D413/12 , C07D413/14

摘要： The present invention relates to non-steroidal progesterone receptor modulators of the general formula I, the use of the progesterone receptor modulators for the manufacture of medicaments, and pharmaceutical compositions which comprise these compounds.The compounds according to the invention are suitable for the therapy and prophylaxis of gynecological disorders such as endometriosis, leiomyomas of the uterus, dysfunctional bleeding and dysmenorrhoea, and for the therapy and prophylaxis of hormone-dependent tumours and for use for female fertility control and for hormone replacement therapy.

摘要翻译： 本发明涉及通式I的非甾体孕激素受体调节剂，孕酮受体调节剂在制备药物中的用途，以及包含这些化合物的药物组合物。根据本发明的化合物适用于治疗和预防妇科疾病如子宫内膜异位症，子宫平滑肌瘤，功能障碍性出血和痛经，以及用于治疗和预防激素依赖性肿瘤和用于女性生育控制和激素替代疗法。

6.

发明申请
Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 审中-公开
标题翻译：四氢萘衍生物，其生产方法及其作为抗炎剂的用途

公开(公告)号：US20070015761A1

公开(公告)日：2007-01-18

申请号：US11399610

申请日：2006-04-07

申请人： Anne Mengel , Konrad Krolikiewicz , Stefan Baeurle , Heike Schaecke

发明人： Anne Mengel , Konrad Krolikiewicz , Stefan Baeurle , Heike Schaecke

IPC分类号： A61K31/517 , A61K31/502 , A61K31/498 , A61K31/4706 , A61K31/4745 , A61K31/4184 , A61K31/416 , A61K31/405

CPC分类号： C07D239/42

摘要： The invention relates to polysubstituted tetrahydronaphthalene derivatives of formula (I), process for their production and their use as anti-inflammatory agents.

摘要翻译： 本发明涉及式（I）的多取代四氢萘衍生物，其制备方法及其作为抗炎剂的用途。

7.

发明申请
Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents 审中-公开

公开(公告)号：US20070015750A1

公开(公告)日：2007-01-18

申请号：US11399590

申请日：2006-04-07

申请人： Stefan Baeurle , Heike Schaecke , Markus Berger , Anne Mengel

发明人： Stefan Baeurle , Heike Schaecke , Markus Berger , Anne Mengel

IPC分类号： A61K31/538 , A61K31/517 , A61K31/502

CPC分类号： C07C49/755 , C07C41/30 , C07C43/23 , C07C45/29 , C07C45/65 , C07C2602/10

摘要： The invention relates to polysubstituted tetrahydronaphthalene derivatives of formula (I), process for their production and their use as anti-inflammatory agents.

8.

发明申请
Substituted pentanols, a process for their production and their use as anti-inflammatory agents 失效
标题翻译：取代的戊醇，其生产方法及其作为抗炎剂的用途

公开(公告)号：US20050143415A1

公开(公告)日：2005-06-30

申请号：US10957742

申请日：2004-10-05

申请人： Stefan Jaroch , Stefan Baeurle , Markus Berger , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Norbert Schmees , Werner Skuballa , Heike Schaecke

发明人： Stefan Jaroch , Stefan Baeurle , Markus Berger , Konrad Krolikiewicz , Duy Nguyen , Hartmut Rehwinkel , Norbert Schmees , Werner Skuballa , Heike Schaecke

IPC分类号： A61K31/47 , C07D215/38 , C07D217/22

CPC分类号： C07D215/38 , C07D217/22

摘要： The invention relates to substituted pentanols, a process for their production and their use as anti-inflammatory agents.

摘要翻译： 本发明涉及取代戊醇，其制备方法及其作为抗炎剂的用途。