公开(公告)号：US09439620B2

公开(公告)日：2016-09-13

申请号：US13992083

申请日：2011-12-01

申请人： Marie Tabaru ,  Takashi Azuma ,  Hideki Yoshikawa ,  Kunio Hashiba

发明人： Marie Tabaru ,  Takashi Azuma ,  Hideki Yoshikawa ,  Kunio Hashiba

IPC分类号： A61B8/00 ,  A61B8/08 ,  G01S7/52

CPC分类号： A61B8/08 ,  A61B8/0825 ,  A61B8/0891 ,  A61B8/485 ,  G01S7/52049 ,  G01S7/52071 ,  G01S7/52073

摘要： When multiple tissues having differing speeds of sound are intermixed in the viewing field of a measured subject such as a living body, the invention measures hardness, such as modulus of elasticity or viscosity, with high precision.

摘要翻译： 当具有不同声速的多个组织混合在诸如生物体的被测量对象的视野中时，本发明以高精度测量诸如弹性模量或粘度的硬度。

公开(公告)号：US20130317361A1

公开(公告)日：2013-11-28

申请号：US13982801

申请日：2011-12-28

申请人： Marie Tabaru ,  Takashi Azuma ,  Hideki Yoshikawa ,  Kunio Hashiba

发明人： Marie Tabaru ,  Takashi Azuma ,  Hideki Yoshikawa ,  Kunio Hashiba

IPC分类号： A61B8/08

CPC分类号： A61B8/485 ,  A61B8/42 ,  A61B8/469 ,  A61B8/5246 ,  G01S7/52042

摘要： An ultrasound diagnostic apparatus with which elastic modulus can be measured when measuring elastic modulus using shear wave generation. The ultrasound diagnostic apparatus includes an ultrasound probe that sends and receives echo signals, a strain-computing unit that receives an echo signal from the body by radiating a first displacement-detecting beam and computes strain information in a Region 1, a measurement position-selecting unit that selects a Region 2, within Region 1, based on the strain information, a displacement-generating unit that radiates a focused beam into the body and displaces the tissue, an elastic modulus-computing unit that receives an echo signal from the body by radiating a second displacement-detecting beam, detects the shear wave displacement that results from the focused beam, and computes the elastic modulus in Region 2, and a display unit that displays the strain image that is based on the strain information in Region 1 and the elastic modulus.

摘要翻译： 一种使用剪切波产生测量弹性模量时可以测量弹性模量的超声波诊断装置。 超声波诊断装置包括发送和接收回波信号的超声波探头，应变计算单元，其通过辐射第一位移检测光束从身体接收回波信号，并计算区域1中的应变信息，测量位置选择 基于应变信息在区域1内选择区域2的单元，将聚焦光束照射到体内并使组织发生位移的位移产生单元，弹性模量计算单元，其从身体接收回波信号， 辐射第二位移检测光束，检测由聚焦光束产生的剪切波位移，并计算区域2中的弹性模量;以及显示单元，其显示基于区域1中的应变信息的应变图像，以及 弹性模量。

公开(公告)号：US20130289402A1

公开(公告)日：2013-10-31

申请号：US13992083

申请日：2011-12-01

申请人： Marie Tabaru ,  Takashi Azuma ,  Hideki Yoshikawa ,  Kunio Hashiba

发明人： Marie Tabaru ,  Takashi Azuma ,  Hideki Yoshikawa ,  Kunio Hashiba

IPC分类号： A61B8/08

CPC分类号： A61B8/08 ,  A61B8/0825 ,  A61B8/0891 ,  A61B8/485 ,  G01S7/52049 ,  G01S7/52071 ,  G01S7/52073

摘要： When multiple tissues having differing speeds of sound are intermixed in the viewing field of a measured subject such as a living body, the invention measures hardness, such as modulus of elasticity or viscosity, with high precision. As a means for detecting heterogeneity of sound speed in the tissues of a subject, a displacement-generating transmission beam is applied from a displacement generating beam-generating device (13) of a displacement-generating unit (10) on an ultrasound probe (1) to irradiate a focused ultrasonic wave into the living tissue and generate a shear wave. From the displacement-time waveforms of multiple positions of the shear wave detected using the displacement detection transmission beam-generating device (22) and the displacement detection received beam-computing device (23) of a displacement-detecting unit (20), at least two pieces of information, such as the integrated value and the maximum amplitude value, are obtained. On the basis of the two pieces of information, a heterogeneity-detecting device (26) of the displacement-detecting unit (20) detects the physical magnitude associated with the heterogeneity in sound speed arising from the tissue structure and displays same on a display (5).

摘要翻译： 当具有不同声速的多个组织混合在诸如生物体的被测量对象的视野中时，本发明以高精度测量诸如弹性模量或粘度的硬度。 作为用于检测被检体的组织中的声速的异质性的手段，从位移产生单元（10）的位移产生光束产生装置（13）向超声波探头（1）施加位移产生透射束 ）将聚焦超声波照射到活体组织中并产生剪切波。 根据位移检测传输光束产生装置（22）检测到的剪切波的多个位置和位移检测单元（20）的位移检测接收光束计算装置（23）的位移时间波形，至少 获得两个信息，例如积分值和最大振幅值。 基于两条信息，位移检测单元（20）的异质性检测装置（26）检测与由组织结构产生的声速异质性相关的物理量值，并将其显示在显示器上 5）。

公开(公告)号：US09370338B2

公开(公告)日：2016-06-21

申请号：US13701838

申请日：2011-05-25

申请人： Kunio Hashiba ,  Hideki Yoshikawa ,  Tatsuya Hayashi

发明人： Kunio Hashiba ,  Hideki Yoshikawa ,  Tatsuya Hayashi

IPC分类号： A61B8/06 ,  A61B8/08 ,  G01S7/52 ,  G01S15/89 ,  A61B8/00 ,  A61B8/14

CPC分类号： A61B8/481 ,  A61B8/08 ,  A61B8/0891 ,  A61B8/5269 ,  G01S7/52038 ,  G01S7/52039 ,  G01S7/52077 ,  G01S15/895 ,  G01S15/8963

摘要： Disclosed is an ultrasound diagnosis device for creating an ultrasound image with a high contrast-to-tissue ratio. Said device sends a transmission pulse to the subject, uses an ultrasound probe to receive echoes reflected from an ultrasound contrast agent injected into the subject, and forms an image. The transmission pulse is sent such that nonlinear interactions between the constituent frequency components of said transmission pulse, as a result of the acoustic nonlinearity of the subject, do not produce sum and difference components in the frequency sensitivity range of the ultrasonic probe as the transmission pulse propagates across the subject.

摘要翻译： 公开了一种用于创建具有高对比度至组织比的超声图像的超声诊断装置。 所述装置向对象发送传输脉冲，使用超声波探头接收从注射到对象中的超声造影剂反射的回波并形成图像。 发送发送脉冲，使得作为对象的声学非线性的结果，所述发送脉冲的构成频率分量之间的非线性相互作用不会在超声波探头的频率灵敏度范围内产生和和差分量作为发送脉冲 传播主题。

公开(公告)号：US20130144172A1

公开(公告)日：2013-06-06

申请号：US13701838

申请日：2011-05-25

申请人： Kunio Hashiba ,  Hideki Yoshikawa ,  Tatsuya Hayashi

发明人： Kunio Hashiba ,  Hideki Yoshikawa ,  Tatsuya Hayashi

IPC分类号： A61B8/08

CPC分类号： A61B8/481 ,  A61B8/08 ,  A61B8/0891 ,  A61B8/5269 ,  G01S7/52038 ,  G01S7/52039 ,  G01S7/52077 ,  G01S15/895 ,  G01S15/8963

摘要： Disclosed is an ultrasound diagnosis device for creating an ultrasound image with a high contrast-to-tissue ratio. Said device sends a transmission pulse to the subject, uses an ultrasound probe to receive echoes reflected from an ultrasound contrast agent injected into the subject, and forms an image. The transmission pulse is sent such that nonlinear interactions between the constituent frequency components of said transmission pulse, as a result of the acoustic nonlinearity of the subject, do not produce sum and difference components in the frequency sensitivity range of the ultrasonic probe as the transmission pulse propagates across the subject.

摘要翻译： 公开了一种用于创建具有高对比度至组织比的超声图像的超声诊断装置。 所述装置向对象发送传输脉冲，使用超声波探头接收从注射到对象中的超声造影剂反射的回波并形成图像。 发送发送脉冲，使得作为对象的声学非线性的结果，所述发送脉冲的构成频率分量之间的非线性相互作用不会在超声波探头的频率灵敏度范围内产生和和差分量作为发送脉冲 传播主题。

公开(公告)号：US09165363B2

公开(公告)日：2015-10-20

申请号：US14236347

申请日：2012-07-24

申请人： Hideki Yoshikawa ,  Takashi Azuma

发明人： Hideki Yoshikawa ,  Takashi Azuma

IPC分类号： G06K9/32 ,  G06T7/00 ,  A61B6/03 ,  A61B6/00 ,  A61B8/08 ,  A61B5/055

CPC分类号： G06T7/003 ,  A61B5/055 ,  A61B6/032 ,  A61B6/461 ,  A61B6/469 ,  A61B6/481 ,  A61B6/486 ,  A61B6/5211 ,  A61B6/5235 ,  A61B6/5241 ,  A61B6/5264 ,  A61B6/58 ,  A61B8/485 ,  A61B8/5207 ,  A61B8/5215 ,  A61B8/5246 ,  A61B2576/00 ,  G06T7/337 ,  G06T2200/24 ,  G06T2207/20104 ,  G06T2207/30004

摘要： Provided is an image diagnostic device with which it is possible to correct location misalignment of an image capture subject, and to improve the reliability of the result of the correction, in time series image data. An image diagnostic device may include an input part (13) which receives image data input; a correction unit (14) which computes a correction vector which denotes location misalignment of an image capture subject, and selects image data used with an image correction unit; an image correction part (20) which carries out a correction process on the image data based on the correction vector and creates corrected image data; a control part (21) which controls the correction unit and the image correction part; a memory (22) which stores the corrected image data and measurement data as stored data; an output unit (23) which outputs the stored data externally; a display unit (24) which displays the stored data; and an external input device (30) where an operator makes an input operation.

摘要翻译： 提供了一种图像诊断装置，可以在时间序列图像数据中校正图像拍摄对象的位置未对准，并且提高校正结果的可靠性。 图像诊断装置可以包括接收图像数据输入的输入部分（13） 校正单元（14），其计算表示图像拍摄对象的位置未对准的校正矢量，并选择与图像校正单元一起使用的图像数据; 图像校正部（20），其基于所述校正矢量对所述图像数据进行校正处理，并生成校正后的图像数据; 控制部件（21），其控制校正单元和图像校正部件; 存储校正图像数据和测量数据作为存储数据的存储器（22）; 输出单元（23），其从外部输出所存储的数据; 显示单元（24），显示所存储的数据; 以及操作者进行输入操作的外部输入装置（30）。

公开(公告)号：US08460191B2

公开(公告)日：2013-06-11

申请号：US11914962

申请日：2006-05-18

申请人： Hideki Yoshikawa ,  Takashi Azuma ,  Kenichi Kawabata ,  Kazuaki Sasaki ,  Shinichiro Umemura

发明人： Hideki Yoshikawa ,  Takashi Azuma ,  Kenichi Kawabata ,  Kazuaki Sasaki ,  Shinichiro Umemura

IPC分类号： A61B8/00

CPC分类号： A61B8/5207 ,  A61B5/11 ,  A61B8/08 ,  A61B8/461 ,  A61B8/463 ,  G06T5/50 ,  G06T7/223 ,  G06T2207/10132 ,  G06T2207/30101

摘要： An diagnostic imaging apparatus for imaging information changing with time and displaying it in real time, composed of an ultrasonic probe (2), having piezoelectric elements arranged in an array form that transmit ultrasonic waves to a target object (1) and acquires a reflection signal from the target object; a body movement measuring unit (12) that constitutes a two-dimensional ultrasonic image using the reflection signal acquired by the ultrasonic probe, sets, in the image plane, a plurality of measuring areas used for measuring the body movement of the target object, and measures the body movement and deformation amounts in the measuring areas; and an image accumulating (subtracting) unit for accumulating or subtracting images using body movement measured by the body movement measurement unit.

摘要翻译： 一种诊断成像装置，用于对随时间变化的图像信息随时间变化并实时显示，该超声波探头由超声波探头（2）组成，该超声波探头具有排列成阵列形式的压电元件，以将超声波传送到目标物体（1）并获取反射信号 从目标对象; 使用由超声波探头取得的反射信号构成二维超声波图像的身体运动测量单元（12）在图像平面中设置用于测量目标物体的身体运动的多个测量区域，以及 测量测量区域的身体运动和变形量; 以及用于通过由身体运动测量单元测量的身体运动来累积或减去图像的图像累积（减去）单元。

公开(公告)号：US20120027282A1

公开(公告)日：2012-02-02

申请号：US13263184

申请日：2010-04-07

申请人： Hideki Yoshikawa ,  Takashi Azuma

发明人： Hideki Yoshikawa ,  Takashi Azuma

IPC分类号： G06K9/00

CPC分类号： G01S15/8979 ,  A61B8/06 ,  A61B8/13 ,  A61B8/463 ,  A61B8/469 ,  A61B8/481 ,  A61B8/483 ,  G01S7/52071 ,  G01S15/8993

摘要： An ultrasonic diagnostic apparatus is provided for displaying a color map on which a difference in blood flow dynamics is reflected. Setting a test subject who is administered a contrast agent is assumed as an imaging target, and a probe transmits and receives ultrasonic waves to and from the target for contrast imaging. Image data is constructed based on signals received by the probe and a time-intensity curve is generated from intensity values of the image data. According to the time-intensity curve, a value of a predetermined parameter is calculated for producing a distribution image of blood flow dynamics. The distribution image (color map) of the blood flow dynamics is produced from the parameter value. The color map is a two-dimensional or a three-dimensional image being color-coded according to the parameter value. At least one of the followings may be used as the parameter; a contrast agent inflow start time, a balanced intensity arrival time, a contrast agent disappearance start time, a contrast agent duration, a preset threshold arrival time, an intensity increase rate, an intensity decrease rate, intensity of balanced state, and a total flow amount.

摘要翻译： 提供超声波诊断装置，用于显示反映血流动力学差异的色图。 设置施用造影剂的测试对象被认为是成像对象，并且探针向对象成像的目标发送和接收超声波。 图像数据是基于由探头接收的信号构成的，并且由图像数据的强度值产生时间 - 强度曲线。 根据时间 - 强度曲线，计算用于产生血流动力学分布图像的预定参数的值。 从参数值产生血流动力学的分布图像（颜色图）。 彩色图是根据参数值进行颜色编码的二维或三维图像。 可以使用以下中的至少一个作为参数; 造影剂流入开始时间，平衡强度到达时间，造影剂消失开始时间，造影剂持续时间，预设阈值到达时间，强度增加率，强度降低率，平衡状态强度和总流量 量。

公开(公告)号：US07758507B2

公开(公告)日：2010-07-20

申请号：US11675711

申请日：2007-02-16

申请人： Hideki Yoshikawa ,  Takashi Azuma

发明人： Hideki Yoshikawa ,  Takashi Azuma

IPC分类号： A61B8/00 ,  G01S13/58 ,  G01F1/66

CPC分类号： A61B8/5276 ,  A61B8/06 ,  A61B8/13

摘要： Blood-flow image display equipment for displaying a CFM image that is not affected by a motion of a tissue in an object area during capturing of images or is affected in a reduced manner. The blood-flow image display equipment has the following components: a transmitting controller for controlling transmission triggers of a signal for B-mode and a signal for CFM based on a velocity of motion of an object; an ultrasonic transducer in which piezoelectric ultrasonic transducers each for transmitting/receiving an ultrasonic wave to/from the object are arranged in the form of an array; a B-mode image construction unit for constructing a B-mode image with received signals; a motion detector for measuring a motion vector of the object using the B-mode image; a receiving unit for CFM signal for receiving the signal for CFM from the ultrasonic transducer; a time-series signal storage unit for CFM that collects a CFM measurement region located in the same area of the object based on the motion vector measured by the motion detector and stores them in memory in time sequence; and an autocorrelation processing unit for performing autocorrelation processing on time-series CFM signals.

摘要翻译： 用于在拍摄图像期间显示不受物体区域内的组织的运动影响的CFM图像的血流图像显示设备，或者以减少的方式影响。 血流图像显示装置具有以下部件：发送控制器，用于基于物体的运动速度控制用于B模式的信号的传输触发和用于CFM的信号; 超声波换能器以阵列的形式布置有用于向/从物体发送/接收超声波的压电超声换能器， B模式图像构造单元，用于构造具有接收信号的B模式图像; 运动检测器，用于使用B模式图像测量对象的运动矢量; 用于CFM信号的接收单元，用于从超声换能器接收用于CFM的信号; 用于CFM的时间序列信号存储单元，其基于由运动检测器测量的运动矢量来收集位于对象的相同区域中的CFM测量区域，并将它们以时间顺序存储在存储器中; 以及自相关处理单元，用于对时间序列CFM信号执行自相关处理。

公开(公告)号：US20100069757A1

公开(公告)日：2010-03-18

申请号：US12529201

申请日：2008-02-07

申请人： Hideki Yoshikawa ,  Takashi Azuma

发明人： Hideki Yoshikawa ,  Takashi Azuma

IPC分类号： A61B8/06

CPC分类号： A61B5/02007 ,  A61B8/06 ,  A61B8/08 ,  A61B8/085 ,  A61B8/0891 ,  A61B8/13 ,  A61B8/463 ,  A61B8/488 ,  A61B8/5223 ,  G01S7/52071 ,  G01S15/8979 ,  G01S15/8984

摘要： An ultrasonic diagnostic apparatus, including a first imaging unit for configuring plural pieces of first-image data based on reception signals received by an ultrasound probe, a velocity vector detector for measuring blood and tissue velocity vectors based on the plural pieces of first-image data inputted from the first imaging unit, a blood-flow image extracting unit for configuring a blood-flow image based on the velocity vectors measured, a histogram unit for calculating number of pixels for each brightness with respect to the blood-flow image configured, a threshold controller for inputting a brightness threshold value, an information processing unit for color-mapping pixels whose brightness are higher than the brightness threshold value, and configuring second-image data by adding the pixels to at least the one piece of first-image data, and a display for displaying the second-image data configured.

摘要翻译： 一种超声波诊断装置，包括：第一摄像部，其基于由超声波探头接收到的接收信号来配置多个第一图像数据;基于多个第一图像数据的血液和组织速度矢量测定用速度矢量检测器 从所述第一成像单元输入的血流图像提取单元，用于基于所测量的速度矢量配置血流图像，用于针对所构成的血流图像计算每个亮度的像素数的直方图单元， 用于输入亮度阈值的阈值控制器，用于对亮度高于亮度阈值的像素进行色彩映射的信息处理单元，以及通过将像素加到至少一条第一图像数据来配置第二图像数据， 以及用于显示配置的第二图像数据的显示器。