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公开(公告)号：US20120059286A1
公开(公告)日：2012-03-08
申请号：US13227446
申请日：2011-09-07
申请人： Roger Hastings , Dave Sogard , Kevin Edmunds , Mark L. Jenson
发明人： Roger Hastings , Dave Sogard , Kevin Edmunds , Mark L. Jenson
CPC分类号： A61B18/1206 , A61B5/0002 , A61B18/1492 , A61B34/25 , A61B2017/00734 , A61B2018/00011 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00642 , A61B2018/00678 , A61B2018/00708 , A61B2018/00744 , A61B2018/00821 , A61B2018/00875 , A61B2018/00916 , A61B2018/00994 , A61B2018/1226 , A61B2018/1861 , A61N7/022
摘要： An ablation catheter includes a flexible shaft having length sufficient to access a patient's renal artery. An electrode arrangement is provided at the distal end of the shaft. A handle unit includes a housing configured for hand-held manipulation and is coupled to the catheter. A battery and one or both of a high frequency AC generator and ultrasound generator are provided in the housing. The battery serves as the sole source of power for the generator. The generator is configured to generate energy sufficient to ablate perivascular renal nerve tissue using energy stored in the battery. The catheter may be disposable and the housing re-usable. Both the catheter and the housing may be disposable.
摘要翻译： 消融导管包括具有足以接近患者肾动脉的长度的柔性轴。 电极布置设置在轴的远端。 手柄单元包括构造成用于手持操作的壳体并且联接到导管。 电池和高频交流发电机和超声波发生器中的一个或两个设置在壳体中。 电池是发电机的唯一电源。 发生器被配置为产生足以使用存储在电池中的能量消融血管周围肾神经组织的能量。 导管可以是一次性的并且壳体可重新使用。 导管和外壳都可以是一次性的。
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公开(公告)号：US08657848B2
公开(公告)日：2014-02-25
申请号：US13253480
申请日：2011-10-05
申请人： Mark L. Jenson , Roger Hastings
发明人： Mark L. Jenson , Roger Hastings
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/016 , A61F2210/009 , A61F2230/005 , A61F2230/0067
摘要： The disclosure pertains to magnetically retrievable vena cava filters having a low torque associated therewith when subjected to a strong external magnetic field and retrieval devices therefor. The vena cava filter may include a magnetically permeable sphere or a spherical dipole magnet located within the spherical cavity of the apical hub wherein the spherical dipole magnet is free to rotate about any of three mutually orthogonal axes. The retrieval device is capable of substantially containing the vena cava filter in a collapsed state and includes a magnetically active member capable of interacting with the vena cava filter. The retrieval device may optionally include a supplemental mechanical latch.
摘要翻译： 本公开涉及具有与其相关联的低扭矩的可磁回收的腔静脉过滤器，当经受强的外部磁场及其检索装置时。 腔静脉过滤器可以包括位于心尖毂的球形空腔内的导磁球体或球形偶极子磁体，其中球形偶极子磁体可以绕任意三个相互正交的轴线旋转。 检索装置能够基本上包含处于折叠状态的腔静脉过滤器，并且包括能够与腔静脉过滤器相互作用的磁性活性构件。 检索装置可以可选地包括补充机械锁存器。
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3.发明申请公开(公告)号：US20120130418A1
公开(公告)日：2012-05-24
申请号：US13253480
申请日：2011-10-05
申请人： Mark L. Jenson , Roger Hastings
发明人： Mark L. Jenson , Roger Hastings
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2002/016 , A61F2210/009 , A61F2230/005 , A61F2230/0067
摘要： The disclosure pertains to magnetically retrievable vena cava filters having a low torque associated therewith when subjected to a strong external magnetic field and retrieval devices therefor. The vena cava filter may include a magnetically permeable sphere or a spherical dipole magnet located within the spherical cavity of the apical hub wherein the spherical dipole magnet is free to rotate about any of three mutually orthogonal axes. The retrieval device is capable of substantially containing the vena cava filter in a collapsed state and includes a magnetically active member capable of interacting with the vena cava filter. The retrieval device may optionally include a supplemental mechanical latch.
摘要翻译： 本公开涉及具有与其相关联的低扭矩的可磁回收的腔静脉过滤器，当经受强的外部磁场及其检索装置时。 腔静脉过滤器可以包括位于心尖毂的球形空腔内的导磁球体或球形偶极子磁体，其中球形偶极子磁体可以绕任意三个相互正交的轴线旋转。 检索装置能够基本上包含处于折叠状态的腔静脉过滤器，并且包括能够与腔静脉过滤器相互作用的磁性活性构件。 检索装置可以可选地包括补充机械锁存器。
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公开(公告)号：US09463062B2
公开(公告)日：2016-10-11
申请号：US13188677
申请日：2011-07-22
申请人： Scott Smith , Joe Koblish , Mark L. Jenson , Roger Hastings
发明人： Scott Smith , Joe Koblish , Mark L. Jenson , Roger Hastings
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2018/00035 , A61B2018/00065 , A61B2018/0016 , A61B2018/0022 , A61B2018/00238 , A61B2018/00285 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00821 , A61B2018/1472
摘要： A catheter includes a flexible shaft having a lumen arrangement and a length sufficient to access a target vessel of a patient. A balloon at the distal end of the shaft is fluidly coupled to the lumen arrangement. The balloon body comprises a first material and a second material different from the first material. The second material comprises a hydrophilic polymer that becomes electrically conductive in response to absorption of the conductive fluid. The fluid conductive regions facilitate perfusion of the conductive fluid through the balloon body to an inner wall of the target vessel during ablation of perivascular tissues. A cooling arrangement is configured for one of receiving a thermal transfer fluid from the lumen arrangement or facilitating perfusion of blood passing through the target vessel to cool the balloon body during ablation of the perivascular tissues.
摘要翻译： 导管包括柔性轴，其具有管腔布置和足以进入患者的目标血管的长度。 在轴的远端处的气囊流体地联接到管腔装置。 球囊体包括第一材料和与第一材料不同的第二材料。 第二种材料包括响应于导电流体的吸收变得导电的亲水性聚合物。 流体导电区域便于在血管周围组织消融期间将导电流体通过球囊体灌注到目标血管的内壁。 冷却装置构造成用于接收来自管腔装置的热转移流体，或者促进血液通过靶血管的灌注，以在血管周围组织消融期间冷却球囊体。
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公开(公告)号：US09060761B2
公开(公告)日：2015-06-23
申请号：US13292766
申请日：2011-11-09
CPC分类号： A61B18/04 , A61B2018/00023 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577
摘要： A flexible catheter includes a magnetically permeable element provided at its distal end. The magnetically permeable element is configured for placement within the renal artery. External coils, positionable on anterior and posterior portions of a patient in proximity to the renal artery, are coupled to a generator which energizes the external coils to create a high-frequency oscillating magnetic field in body tissue between the external coils including the renal artery and perivascular renal nerve tissue. The magnetically permeable element serves to concentrate the magnetic field in a region near the renal artery. The concentrated magnetic field induces high frequency electric current sufficient to ablate the perivascular renal nerve tissue proximate the renal artery. A cooling arrangement can be provided at the catheter's distal end and configured to provide cooling to the renal artery during ablation of the perivascular renal nerve tissue.
摘要翻译： 柔性导管包括设置在其远端处的导磁元件。 导磁元件构造成放置在肾动脉内。 位于靠近肾动脉的患者的前部和后部的外部线圈被耦合到发电机，该发电机激励外部线圈，以在包括肾动脉和外周线圈的外部线圈之间的身体组织中产生高频振荡磁场， 血管周围肾神经组织。 导磁元件用于将磁场集中在肾动脉附近的区域。 集中的磁场诱发高频电流足以消融肾动脉附近的血管周围肾神经组织。 可以在导管的远端处提供冷却装置，并且构造成在血管周围肾神经组织的消融期间向肾动脉提供冷却。
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公开(公告)号：US20120130362A1
公开(公告)日：2012-05-24
申请号：US13292766
申请日：2011-11-09
IPC分类号： A61B18/18
CPC分类号： A61B18/04 , A61B2018/00023 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577
摘要： A flexible catheter includes a magnetically permeable element provided at its distal end. The magnetically permeable element is configured for placement within the renal artery. External coils, positionable on anterior and posterior portions of a patient in proximity to the renal artery, are coupled to a generator which energizes the external coils to create a high-frequency oscillating magnetic field in body tissue between the external coils including the renal artery and perivascular renal nerve tissue. The magnetically permeable element serves to concentrate the magnetic field in a region near the renal artery. The concentrated magnetic field induces high frequency electric current sufficient to ablate the perivascular renal nerve tissue proximate the renal artery. A cooling arrangement can be provided at the catheter's distal end and configured to provide cooling to the renal artery during ablation of the perivascular renal nerve tissue.
摘要翻译： 柔性导管包括设置在其远端处的导磁元件。 导磁元件构造成放置在肾动脉内。 位于靠近肾动脉的患者的前部和后部的外部线圈被耦合到发电机，该发电机激励外部线圈，以在包括肾动脉和外周线圈的外部线圈之间的身体组织中产生高频振荡磁场， 血管周围肾神经组织。 导磁元件用于将磁场集中在肾动脉附近的区域。 集中的磁场诱发高频电流足以消融肾动脉附近的血管周围肾神经组织。 可以在导管的远端处提供冷却装置，并且构造成在血管周围肾神经组织的消融期间向肾动脉提供冷却。
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7.发明申请RENAL DENERVATION CATHETER EMPLOYING ACOUSTIC WAVE GENERATOR ARRANGEMENT 审中-公开使用声波发生器装置的RENAL DENERVATION CATHETER公开(公告)号：US20120109021A1
公开(公告)日：2012-05-03
申请号：US13283203
申请日：2011-10-27
申请人： Roger Hastings , Mark L. Jenson
发明人： Roger Hastings , Mark L. Jenson
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B2017/22021 , A61B2017/22024 , A61N2007/003 , A61N2007/0073
摘要： A transducer supported by a positioning arrangement is placed within a renal artery at a desired location that is a predetermined distance from a reflector equal to an odd number of quarter wavelengths of acoustic energy emitted by the transducer. The positioning arrangement is actuated to transition from a low-profile introduction configuration to a deployed configuration within the renal artery thereby stabilizing the transducer at a desired location. Acoustic energy is emitted by the transducer so that it propagates axially along an outer surface of the target vessel to impinge the reflector, which can be biological or artificial. The emitted energy builds up to resonance at a point of reflection defined by a location of the reflector, and the amount of energy build up is sufficient to ablate perivascular renal nerves in the vicinity of the reflector.
摘要翻译： 由定位装置支撑的换能器放置在与反射器相距预定距离的期望位置处的肾动脉内，所述反射器等于由换能器发射的声能的奇数个四分之一波长。 定位装置被致动以从低轮廓引入配置转变到肾动脉内的部署配置，从而将换能器稳定在期望的位置。 传声器发出声能，使其沿目标容器的外表面轴向传播，以撞击可能是生物或人造的反射器。 发射的能量在由反射器的位置限定的反射点处形成共振，并且积聚的能量足以消除反射器附近的血管周围肾神经。
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公开(公告)号：US20120029511A1
公开(公告)日：2012-02-02
申请号：US13188677
申请日：2011-07-22
申请人： Scott Smith , Joe Koblish , Mark L. Jenson , Roger Hastings
发明人： Scott Smith , Joe Koblish , Mark L. Jenson , Roger Hastings
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2018/00029 , A61B2018/00035 , A61B2018/00065 , A61B2018/0016 , A61B2018/0022 , A61B2018/00238 , A61B2018/00285 , A61B2018/00404 , A61B2018/00434 , A61B2018/00505 , A61B2018/00511 , A61B2018/00577 , A61B2018/00821 , A61B2018/1472
摘要： A catheter includes a flexible shaft having a lumen arrangement and a length sufficient to access a target vessel of a patient. A balloon at the distal end of the shaft is fluidly coupled to the lumen arrangement. The balloon body comprises a first material and a second material different from the first material. The second material comprises a hydrophilic polymer that becomes electrically conductive in response to absorption of the conductive fluid. The fluid conductive regions facilitate perfusion of the conductive fluid through the balloon body to an inner wall of the target vessel during ablation of perivascular tissues. A cooling arrangement is configured for one of receiving a thermal transfer fluid from the lumen arrangement or facilitating perfusion of blood passing through the target vessel to cool the balloon body during ablation of the perivascular tissues.
摘要翻译： 导管包括柔性轴，其具有管腔布置和足以进入患者的目标血管的长度。 在轴的远端处的气囊流体地联接到管腔装置。 球囊体包括第一材料和与第一材料不同的第二材料。 第二种材料包括响应于导电流体的吸收变得导电的亲水性聚合物。 流体导电区域便于在血管周围组织消融期间将导电流体通过球囊体灌注到目标血管的内壁。 冷却装置构造成用于接收来自管腔装置的热转移流体，或者促进血液通过靶血管的灌注，以在血管周围组织消融期间冷却球囊体。
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公开(公告)号：US09254124B2
公开(公告)日：2016-02-09
申请号：US12026207
申请日：2008-02-05
CPC分类号： A61B17/0057 , A61B17/0469 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/047 , A61B2017/0472 , A61B2017/3484 , A61B2090/067 , A61B2090/0811
摘要： A device is disclosed for providing an indication as to the relative position of a vessel or artery opening thereby facilitating the choice of which several closure techniques to use. A disclosed device includes an outer tube and a collapsible foot slidably disposed within a distal end of the outer tube. The device may further include one or more threaded suture needles, a biodegradable plug or other wound closing device that is connected to another shaft. The collapsed or folded foot is pushed distally out of the tube and through the opening in the vessel whereupon the foot expands. Pulling the expanded foot in the proximal direction provides an indication as to the orientation of the opening in the vessel, which assists in determining the type of closing procedure to be carried out.
摘要翻译： 公开了一种用于提供关于血管或动脉开口的相对位置的指示的装置，从而便于选择使用哪些闭合技术。 所公开的装置包括外管和可滑动地设置在外管的远端内的可折叠的脚。 该装置还可以包括一个或多个螺纹缝合针，可生物降解的塞子或其它连接到另一轴的闭合装置。 折叠或折叠的脚从管中向远侧推出并穿过容器中的足部膨胀的开口。 沿着近端方向拉动扩张的脚提供关于容器中的开口的取向的指示，这有助于确定要执行的关闭程序的类型。
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公开(公告)号：US09044350B2
公开(公告)日：2015-06-02
申请号：US11507103
申请日：2006-08-21
CPC分类号： A61F2/856 , A61F2/852 , A61F2/86 , A61F2/954 , A61F2002/067 , A61F2220/005 , A61F2220/0058 , A61F2230/001 , A61F2230/0043 , A61F2250/006
摘要： The invention is direction to an alignment apparatus comprising a central sheath, an alignment sheath, and at least one stent. The central sheath and the alignment sheath each have a wall and a distal end where the wall of the alignment sheath is engaged to the wall of the central sheath. The wall of the central sheath defines a central lumen that has a central guide wire extending therethrough and the wall of the alignment sheath defines an alignment lumen that has an alignment guide wire extending therethrough. The distal end of the alignment sheath is positioned proximally to the distal end of the central sheath. The alignment apparatus has at least one stent disposed about one of the alignment guide wire or the central guide wire. The at least one stent has a pre-delivered state so that when the at least one stent is in the pre-delivered state, it is contained within at least one of the central sheath and the alignment sheath.
摘要翻译： 本发明是包括中心护套，对准护套和至少一个支架的对准装置的方向。 中心护套和对准护套均具有壁和远端，其中对准护套的壁与中心护套的壁接合。 中心护套的壁限定了具有延伸穿过其中的中心导丝的中心管，并且对准护套的壁限定了具有延伸穿过其中的对准导丝的对准内腔。 对准护套的远端位于中央护套的远端的近侧。 对准装置具有至少一个支架，其布置在对准引导线或中心引导线之一附近。 至少一个支架具有预输送状态，使得当至少一个支架处于预输送状态时，其被包含在至少一个中心护套和对准护套中。
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