公开(公告)号：US5929385A

公开(公告)日：1999-07-27

申请号：US850184

申请日：1997-05-02

申请人： Masahiro Sugimoto ,  Akio Kimura ,  Masanao Mimura ,  Hideo Ishii ,  Shoichi Honjo ,  Yoshihiro Iwata

发明人： Masahiro Sugimoto ,  Akio Kimura ,  Masanao Mimura ,  Hideo Ishii ,  Shoichi Honjo ,  Yoshihiro Iwata

IPC分类号： H01L39/14 ,  H01B12/00

CPC分类号： H01L39/143

摘要： Disclosed is an AC oxide superconductor round wire including a metal matrix, and a plurality of superconductor filaments embedded in the metal matrix, wherein the superconductor filaments are twisted at a twist pitch L.sub.p satisfying the following relation.2L.sub.c1

摘要翻译： 公开了一种包含金属基体的AC氧化物超导体圆线和嵌入在金属基体中的多根超导体丝，其中超导体长丝以满足以下关系的扭曲节距Lp扭曲.2Lc1

公开(公告)号：US09359143B2

公开(公告)日：2016-06-07

申请号：US14309485

申请日：2014-06-19

申请人： Kouetsu Ishii ,  Shinji Katsuta ,  Akio Kimura ,  Shigeyoshi Nishihara ,  Toshiyuki Iba ,  Yutaro Hyogo

发明人： Kouetsu Ishii ,  Shinji Katsuta ,  Akio Kimura ,  Shigeyoshi Nishihara ,  Toshiyuki Iba ,  Yutaro Hyogo

IPC分类号： B65G47/00 ,  B65G37/00 ,  B61B13/02 ,  B65G35/06

CPC分类号： B65G37/005 ,  B61B13/02 ,  B65G35/066 ,  B65G2201/0294

摘要： A conveyance device has a carriage drive for driving and propelling a pair of left and right carriage units which individually support left and right sides of an object to be conveyed. A pair of left and right screw shafts is pivotally supported in a rotatable manner along the movement path of the carriage units. Driven rollers are pivotally supported in a rotatable manner by the carriage units and engage with the screw shafts. A transmission connects the pair of left and right screw shafts through the outside of a conveyance path such that the left and right screw shafts are linked and coupled; and a single motor drives the pair of left and right screw shafts through the transmission means.

摘要翻译： 输送装置具有用于驱动和推进一对左右的支架单元的托架驱动装置，它们分别支撑待运送物体的左右两侧。 一对左右螺杆轴沿着滑架单元的移动路径可旋转地支承。 驱动辊由滑架单元以可旋转的方式可枢转地支撑并与螺杆轴接合。 传动装置将一对左，右螺丝轴通过输送路径的外部连接，使得左右螺杆轴连接并联接; 并且单个电动机通过传动装置驱动该对左右螺杆轴。

公开(公告)号：US08686006B2

公开(公告)日：2014-04-01

申请号：US13124797

申请日：2009-10-22

申请人： Masayuki Umeda ,  Akio Kimura ,  Kenji Ueda ,  Koji Sakanaka

发明人： Masayuki Umeda ,  Akio Kimura ,  Kenji Ueda ,  Koji Sakanaka

IPC分类号： A61K31/44

CPC分类号： A61K31/4409

摘要： An object of the present invention is to provide a pharmaceutical composition that improves intestinal absorption of a compound having a structure represented by the general formula [1]. The composition containing a compound represented by the general formula [1] or a salt thereof and (b) a lipophilic substance improves intestinal absorption of the compound. In the formula, A represents —(NR4)—, —(CR5R6)— or the like; B represents an alkylene group or an alkenylene group; R1 represents an alkyl group, an alkenyl group or the like; R2 represents an adamantylalkyl group or the like; R3 represents an unsaturated heterocyclic ring; R4, R5 and R6 each represent a hydrogen atom or the like; and X represents an oxygen atom or the like.

摘要翻译： 本发明的目的是提供一种改善具有由通式[1]表示的结构的化合物的肠吸收的药物组合物。 包含由通式[1]表示的化合物或其盐和（b）亲脂性物质的组合物改善了化合物的肠吸收。 在该式中，A表示 - （NR 4） - ， - （CR 5 R 6） - 等; B表示亚烷基或亚烯基; R1表示烷基，烯基等; R2表示金刚烷基烷基等; R3表示不饱和杂环; R4，R5和R6各自表示氢原子等; X表示氧原子等。

公开(公告)号：US08324271B2

公开(公告)日：2012-12-04

申请号：US13136309

申请日：2011-07-28

申请人： Hiroyuki Asada ,  Akio Kimura

发明人： Hiroyuki Asada ,  Akio Kimura

IPC分类号： A61K31/215

CPC分类号： A61K47/18 ,  A61K9/0048 ,  A61K31/5575 ,  Y10S514/912 ,  Y10S514/913

摘要： An eye drop composition in which the degradation of isopropyl unoprostone in an eye drop is prevented by adding trometamol to the eye drop containing isopropyl unoprostone.

摘要翻译： 通过向包含异丙基非石榴石的滴眼剂中加入氨甲醇来防止滴眼剂中的异丙基异佛鲁酮降解的滴眼剂组合物。

公开(公告)号：US20120172577A1

公开(公告)日：2012-07-05

申请号：US11909873

申请日：2006-03-31

申请人： Tetsuo Kase ,  Akio Kimura ,  Hiroshi Kisaki ,  Yoko Kisaki ,  Hiroyuki Keshi ,  Aya Keshi ,  Hiroshi Ueyama ,  Mizuki Nishihara

发明人： Tetsuo Kase ,  Akio Kimura ,  Hiroshi Kisaki ,  Yoko Kisaki ,  Hiroyuki Keshi ,  Aya Keshi ,  Hiroshi Ueyama ,  Mizuki Nishihara

IPC分类号： C07K14/78 ,  C12N15/85 ,  C12N5/10 ,  C12P21/00

CPC分类号： C12P21/02 ,  C07K14/78

摘要： An objective of the present invention is to provide methods of producing human collagen molecules that are easy to isolate and purify and that have a structure substantially equivalent to that of a natural collagen molecule, wherein host cells that are transduced with a collagen gene synthesize large amounts of human collagen protein derived from a gene introduced into a high exogenous gene expression vector. Another objective of the present invention is to provide collagen molecules produced by the production methods.The present inventors discovered that a large amount of human collagen hardly contaminated with host cell-derived collagen could be produced, by selecting from various mammalian cells a host cell that has low collagen expression and introducing a collagen gene construct into a vector capable of high exogenous gene expression.

摘要翻译： 本发明的目的是提供生产易于分离和纯化的人胶原分子的方法，其具有与天然胶原分子基本上相同的结构，其中用胶原基因转导的宿主细胞合成大量 的衍生自引入高外源基因表达载体的基因的人胶原蛋白。 本发明的另一个目的是提供通过生产方法制备的胶原分子。 本发明人发现，通过从各种哺乳动物细胞中选择具有低胶原表达的宿主细胞并将胶原基因构建体导入能够高度外源的载体中，可以产生几乎不被宿主细胞衍生的胶原蛋白污染的大量人胶原 基因表达。

公开(公告)号：US08030349B2

公开(公告)日：2011-10-04

申请号：US11989128

申请日：2006-08-02

申请人： Hiroyuki Asada ,  Akio Kimura

发明人： Hiroyuki Asada ,  Akio Kimura

IPC分类号： A61K31/215

CPC分类号： A61K47/18 ,  A61K9/0048 ,  A61K31/5575 ,  Y10S514/912 ,  Y10S514/913

摘要： The present invention provides a method for preventing the degradation of a thermally unstable medicament in an eye drop containing the medicament thereby to stabilize the eye drop. By adding an organic amine to an eye drop containing a thermally unstable medicament, the degradation of the medicament in the eye drop can be effectively prevented, and therefore the eye drop can be stably stored.

摘要翻译： 本发明提供一种防止含有药物的滴眼剂中热不稳定药物降解的方法，从而稳定滴眼剂。 通过向含有热不稳定性药剂的滴眼剂中添加有机胺，能够有效地防止滴眼剂中的药剂的降解，能够稳定地保存眼药水。

公开(公告)号：US20060074053A1

公开(公告)日：2006-04-06

申请号：US11283674

申请日：2005-11-22

申请人： Hiroyuki Asada ,  Akio Kimura

发明人： Hiroyuki Asada ,  Akio Kimura

IPC分类号： A61K31/496 ,  A61K31/4704 ,  A61K31/716 ,  A61K9/14

CPC分类号： A61K9/0048 ,  A61K31/4725 ,  A61K31/496

摘要： The present invention provides an ophthalmic solution containing as the active ingredient a quinolone antimicrobial compound, wherein at least one member selected from the group consisting of water-soluble vinyl polymeric compounds and water-soluble cellulose derivatives is formulated into the ophthalmic solution to prevent the quinolone antimicrobial compound from precipitating when the ophthalmic solution comes in contact with the lacrimal fluid after instillation.

摘要翻译： 本发明提供了含有作为活性成分的喹诺酮抗微生物化合物的眼用溶液，其中将选自水溶性乙烯基聚合物和水溶性纤维素衍生物的至少一种配制成眼用溶液以防止喹诺酮 抗微生物化合物在滴眼液当泪液与泪液接触时沉淀。

公开(公告)号：US06076242A

公开(公告)日：2000-06-20

申请号：US125195

申请日：1998-08-13

申请人： Katsuyuki Kasaoka ,  Shigeru Takahashi ,  Mitsuo Matsumoto ,  Akio Kimura

发明人： Katsuyuki Kasaoka ,  Shigeru Takahashi ,  Mitsuo Matsumoto ,  Akio Kimura

IPC分类号： D01F6/62 ,  D02G1/18 ,  D03D15/04 ,  D03D27/00 ,  D04B1/04 ,  D04B21/04 ,  D06C11/00 ,  D06C7/02

CPC分类号： D04B1/04 ,  D03D15/04 ,  D03D27/00 ,  D04B21/04 ,  Y10T428/23936 ,  Y10T428/23957

摘要： A cut pile fabric with substantially vertically standing tufts made of a synthetic multifilament yarn which is an intermingled yarn comprised of (a) a crimped multifilament yarn and (b) a non-crimped highly heat-shrinkable multifilament yarn having a heat shrinkage larger than that of the crimped multifilament yarn (a), and having thick portions and thin portions, alternately occurring along the length of each constituting filament of the yarn (b), said thick portions having a heat shrinkage larger than that of said thin portions. When heat-treated, the cut pile fabric provides a high-and-low cut pile fabric having a unique appearance. Especially when tip portions of cut piles of the crimped multifilament yarn (a) are entangled with each other, a cut pile fabric having a rugged surface with lumps of snarled piles is obtained.

摘要翻译： PCT No.PCT / JP97 / 04581 Sec。 371日期1998年8月13日 102（e）日期1998年8月13日PCT 1997年12月12日PCT PCT。 第WO98 / 26119号公报 日期1998年6月18日一种由合成复丝纱线制成的基本上垂直立起的绒毛的切绒织物，该合成复丝纱线是由（a）卷曲复丝纱线和（b）非卷曲的高热收缩复丝纱线组成的混纺纱线， 热收缩率大于卷曲复丝纱线（a）的热收缩率，并且具有厚度部分和薄部分，沿着每个构成丝线（b）长丝的长度交替发生，所述厚部分的热收缩率大于所述 薄的部分。 经过热处理后，切绒织物提供了具有独特外观的高低切绒头织物。 特别是当卷曲的复丝纱线（a）的切割桩的尖端部彼此缠结时，获得具有崎岖的疙瘩堆积的粗糙表面的切割绒头织物。

公开(公告)号：US5545349A

公开(公告)日：1996-08-13

申请号：US210418

申请日：1994-03-18

申请人： Jun Kurii ,  Noboru Nomura ,  Masami Itoh ,  Kozo Ohira ,  Masaki Tsumadori ,  Akira Matsunaga ,  Akio Kimura ,  Shigetoshi Suzue

发明人： Jun Kurii ,  Noboru Nomura ,  Masami Itoh ,  Kozo Ohira ,  Masaki Tsumadori ,  Akira Matsunaga ,  Akio Kimura ,  Shigetoshi Suzue

IPC分类号： C11D3/39 ,  C09K3/00 ,  C01B15/10

CPC分类号： C11D3/391

摘要： A bleaching composition comprising:(a) Hydrogen peroxide or peroxide that produces hydrogen peroxide in aqueous solution; and(b) An organic acid peroxide precursor that produces organic acid peroxide by reacting with said hydrogen peroxide or peroxide that produces hydrogen peroxide in aqueous solution, wherein said organic acid peroxide is represented by general formula (I): ##STR1## wherein R.sup.1 represents a straight chain or branched chain alkyl or alkenyl group having 1-5 carbon atoms, R.sup.2 represents a straight chain or branched chain alkylene group having 1-8 carbon atoms or a phenylene group that may be substituted with a straight chain or branched chain alkyl group having 1-5 carbon atoms, A represent identical or different alkylene groups having from 2 to 4 carbon atoms, and n represents an integer from 0-100.

摘要翻译： 一种漂白组合物，其包含：（a）在水溶液中产生过氧化氢的过氧化氢或过氧化物; （b）通过与在水溶液中产生过氧化氢的所述过氧化氢或过氧化物反应产生有机过氧化氢的有机过氧化氢前体，其中所述有机过氧化物由通式（I）表示： 其中R1表示具有1-5个碳原子的直链或支链烷基或烯基，R2表示具有1-8个碳原子的直链或支链亚烷基或可以被直链或支链取代的亚苯基 具有1-5个碳原子的链烷基，A表示具有2至4个碳原子的相同或不同的亚烷基，n表示0-100的整数。

公开(公告)号：US5104981A

公开(公告)日：1992-04-14

申请号：US494360

申请日：1990-03-16

申请人： Akira Yamamuro ,  Makoto Amau ,  Tadaaki Fujita ,  Kiyoshi Aimono ,  Akio Kimura

发明人： Akira Yamamuro ,  Makoto Amau ,  Tadaaki Fujita ,  Kiyoshi Aimono ,  Akio Kimura

IPC分类号： C07H15/04

CPC分类号： C07H15/04

摘要： A process is disclosed for the production of an alkyl glycoside excellent in hue, which comprises (1) reacting a sugar with alcohol to obtain an alkyl glycoside reaction product containing an unreacted higher alcohol, (2) reacting the resulting product with a metal/hydrogen complex represented by formula (I)M(BH.sub.4).sub.x (I)whereinM is an alkali metal, Ca, Zn, or (CH.sub.3).sub.4 N; and x is 1 when M is an alkali metal or (CH.sub.3).sub.4 N and x is 2 when M is Ca or Zn;(3) separating the resulting reaction mixture into the alkyl glycoside and the unreacted higher alcohol, and (4) decomposing the remaining metal/hydrogen complex with an acid.