公开(公告)号：US07849843B2

公开(公告)日：2010-12-14

申请号：US12060456

申请日：2008-04-01

申请人： Masami Kojima ,  Takashi Tauchi ,  Takeshi Morimoto ,  Atsushi Iwami ,  Yoshitaka Satoh ,  Shuichi Matsubayashi ,  Ikuo Hirayama

发明人： Masami Kojima ,  Takashi Tauchi ,  Takeshi Morimoto ,  Atsushi Iwami ,  Yoshitaka Satoh ,  Shuichi Matsubayashi ,  Ikuo Hirayama

IPC分类号： F02P3/02

CPC分类号： H01F38/12

摘要： An ignition coil is equipped with a sparkplug of an engine. The ignition coil includes a coil portion, a tower portion, and a plug cap. The coil portion includes a coil case accommodating a primary and secondary coils being coaxial with each other. The coil portion has an end connected with the plug cap via the tower portion. The plug cap is press-fitted with the sparkplug. The coil case has an outer periphery from which a flange portion projects radially outward in a flange-projecting direction. The tower cylinder portion has a tower axis substantially in parallel with a coil axis of the primary and secondary coils. The tower axis is offset from the coil axis in a tower-offset direction. The tower-offset direction is substantially the same as the flange-projecting direction.

摘要翻译： 点火线圈配有发动机的火花塞。 点火线圈包括线圈部分，塔架部分和塞帽。 线圈部分包括容纳彼此同轴的初级和次级线圈的线圈壳体。 线圈部分具有经由塔架部分与塞帽连接的端部。 插头盖与火花塞压配合。 线圈壳体具有外周，凸缘部在该外周缘沿凸缘方向从径向向外突出。 塔筒部分具有与初级和次级线圈的线圈轴线基本平行的塔架轴线。 塔轴在塔偏移方向上偏离线圈轴。 塔偏移方向基本上与凸缘方向相同。

公开(公告)号：US20090194084A1

公开(公告)日：2009-08-06

申请号：US12060456

申请日：2008-04-01

申请人： Masami Kojima ,  Takashi Tauchi ,  Takeshi Morimoto ,  Atsushi Iwami ,  Yoshitaka Satoh ,  Shuichi Matsubayashi ,  Ikuo Hirayama

发明人： Masami Kojima ,  Takashi Tauchi ,  Takeshi Morimoto ,  Atsushi Iwami ,  Yoshitaka Satoh ,  Shuichi Matsubayashi ,  Ikuo Hirayama

IPC分类号： H01F38/12

CPC分类号： H01F38/12

摘要： An ignition coil is equipped with a sparkplug of an engine. The ignition coil includes a coil portion, a tower portion, and a plug cap. The coil portion includes a coil case accommodating a primary and secondary coils being coaxial with each other. The coil portion has an end connected with the plug cap via the tower portion. The plug cap is press-fitted with the sparkplug. The coil case has an outer periphery from which a flange portion projects radially outward in a flange-projecting direction. The tower cylinder portion has a tower axis substantially in parallel with a coil axis of the primary and secondary coils. The tower axis is offset from the coil axis in a tower-offset direction. The tower-offset direction is substantially the same as the flange-projecting direction.

摘要翻译： 点火线圈配备有发动机的火花塞。 点火线圈包括线圈部分，塔架部分和塞帽。 线圈部分包括容纳彼此同轴的初级和次级线圈的线圈壳体。 线圈部分具有经由塔架部分与塞帽连接的端部。 插头盖与火花塞压配合。 线圈壳体具有外周，凸缘部在该外周缘沿凸缘方向从径向向外突出。 塔筒部分具有与初级和次级线圈的线圈轴线基本平行的塔架轴线。 塔轴在塔偏移方向上偏离线圈轴。 塔偏移方向基本上与凸缘方向相同。

公开(公告)号：US07317370B2

公开(公告)日：2008-01-08

申请号：US11707950

申请日：2007-02-20

申请人： Kiyotoshi Nakamoto ,  Yoshitaka Satoh

发明人： Kiyotoshi Nakamoto ,  Yoshitaka Satoh

IPC分类号： H01F27/02 ,  H01F38/12

CPC分类号： H01F38/12 ,  H01F27/022 ,  H01F27/04 ,  H01F27/33 ,  H01F2038/122

摘要： An ignition coil includes a coil portion that has a primary coil, a secondary coil, and an outer core. The outer core is arranged on a radially outer side of both the primary coil and the secondary coil. A fitting member, which is in a substantially cylindrical shape, has an inner periphery via which the fitting member is fitted to the outer core. A connector case has a fit hole via which the connector case is fitted to an outer periphery of the fitting member. The connector case connects with an axial end of the coil portion via the fitting member. The fitting member includes an embedded member that is at least partially embedded in the fitting member. The embedded member is formed of a material that is different in Young's modulus from a material constructing the fitting member.

摘要翻译： 点火线圈包括具有初级线圈，次级线圈和外芯的线圈部分。 外芯布置在初级线圈和次级线圈的径向外侧。 大致圆筒状的嵌合部件具有内周面，嵌合部件经由该内周嵌合于外芯。 连接器壳体具有配合孔，连接器壳体通过该配合孔装配到配件的外周。 连接器壳体经由配合构件与线圈部分的轴向端部连接。 装配构件包括至少部分地嵌入在装配构件中的嵌入构件。 嵌入构件由与构成配合构件的材料的杨氏模量不同的材料形成。

公开(公告)号：US07220771B2

公开(公告)日：2007-05-22

申请号：US10673121

申请日：2003-09-26

申请人： Shripad S. Bhagwat ,  Yoshitaka Satoh ,  Steven T. Sakata ,  Chris A. Buhr ,  Ronald Albers ,  John Sapienza ,  Veronique Plantevin ,  Qi Chao ,  Kiran Sahasrabudhe ,  Rachel Ferri

发明人： Shripad S. Bhagwat ,  Yoshitaka Satoh ,  Steven T. Sakata ,  Chris A. Buhr ,  Ronald Albers ,  John Sapienza ,  Veronique Plantevin ,  Qi Chao ,  Kiran Sahasrabudhe ,  Rachel Ferri

IPC分类号： A61K31/416 ,  A61K31/41

CPC分类号： C07D403/12 ,  C07D231/56 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/12

摘要： Compounds having activity as selective inhibitors of JNK are disclosed. The compounds of this invention are indazole derivatives having the following structure: wherein R1, R2 and A are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to JNK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.

摘要翻译： 公开了具有活性作为JNK的选择性抑制剂的化合物。 本发明的化合物是具有以下结构的吲唑衍生物：其中R 1，R 2和A如本文所定义。 这些化合物可用于治疗对JNK抑制作用有响应的广泛范围的病症。 因此，还公开了治疗这些病症的方法，以及含有一种或多种上述化合物的化合物的药物组合物。

公开(公告)号：US20070060598A1

公开(公告)日：2007-03-15

申请号：US11411413

申请日：2006-04-26

申请人： Ronald Albers ,  Leticia Ayala ,  Steven Clareen ,  Maria Delgado Mederos ,  Robert Hilgraf ,  Sayee Hegde ,  Kevin Hughes ,  Adam Kois ,  Veronique Plantevin-Krenitsky ,  Meg McCarrick ,  Lisa Nadolny ,  Moorthy Palanki ,  Kiran Sahasrabudhe ,  John Sapienza ,  Yoshitaka Satoh ,  Marianne Sloss ,  Elise Sudbeck ,  Jonathan Wright

发明人： Ronald Albers ,  Leticia Ayala ,  Steven Clareen ,  Maria Delgado Mederos ,  Robert Hilgraf ,  Sayee Hegde ,  Kevin Hughes ,  Adam Kois ,  Veronique Plantevin-Krenitsky ,  Meg McCarrick ,  Lisa Nadolny ,  Moorthy Palanki ,  Kiran Sahasrabudhe ,  John Sapienza ,  Yoshitaka Satoh ,  Marianne Sloss ,  Elise Sudbeck ,  Jonathan Wright

IPC分类号： A61K31/52 ,  C07D473/14

CPC分类号： A61K31/52 ,  C07D473/32

摘要： Provided herein are Aminopurine Compounds having the following structure: wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.

摘要翻译： 本文提供具有以下结构的氨基嘌呤化合物：其中R 1，R 2和R 3如本文所定义，包含有效量的组合物 的氨基嘌呤化合物和治疗或预防癌症，心血管疾病，肾脏疾病，自身免疫病症，炎性病症，黄斑变性，缺血再灌注损伤，疼痛和相关综合征，疾病相关性消耗，石棉相关的方法 条件，肺动脉高压或通过抑制JNK途径可治疗或可预防的病症，包括向有需要的患者施用有效量的氨基嘌呤化合物。

公开(公告)号：US07122544B2

公开(公告)日：2006-10-17

申请号：US10004642

申请日：2001-12-04

申请人： Adam Kois ,  Karen J. MacFarlane ,  Yoshitaka Satoh ,  Shripad S. Bhagwat ,  Jason S. Parnes ,  Moorthy S. S. Palanki ,  Paul E. Erdman

发明人： Adam Kois ,  Karen J. MacFarlane ,  Yoshitaka Satoh ,  Shripad S. Bhagwat ,  Jason S. Parnes ,  Moorthy S. S. Palanki ,  Paul E. Erdman

IPC分类号： A61K31/506 ,  C07D403/04

CPC分类号： C07D239/42 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12

摘要： Compounds having activity as inhibitors of IKK are disclosed, particularly IKK-2. The compounds of this invention are anilinopyrimidine derivatives having the following structure: wherein R1 and R6 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to IKK inhibition. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.

摘要翻译： 公开了具有IKK抑制剂活性的化合物，特别是IKK-2。 本发明的化合物是具有以下结构的苯胺基嘧啶衍生物：其中R 1和R 6如本文所定义。 这些化合物可用于治疗对IKK抑制有反应的广泛范围的病症。 因此，还公开了治疗这些病症的方法，以及含有一种或多种上述化合物的化合物的药物组合物。

公开(公告)号：US20050009876A1

公开(公告)日：2005-01-13

申请号：US10718185

申请日：2003-11-19

申请人： Shripad Bhagwat ,  Yoshitaka Satoh ,  Steven Sakata ,  Chris Buhr ,  Ronald Albers ,  John Sapienza ,  Veronique Plantevin ,  Qi Chao ,  Kiran Sahasrabudhe ,  Rachel Ferri ,  Rama Narla

发明人： Shripad Bhagwat ,  Yoshitaka Satoh ,  Steven Sakata ,  Chris Buhr ,  Ronald Albers ,  John Sapienza ,  Veronique Plantevin ,  Qi Chao ,  Kiran Sahasrabudhe ,  Rachel Ferri ,  Rama Narla

IPC分类号： A61K31/416 ,  C07D231/56 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/12 ,  A61K31/4439 ,  A61K31/4162 ,  C07

CPC分类号： A61K31/454 ,  A61K31/416 ,  C07D231/56 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D405/04 ,  C07D405/12 ,  C07D405/14 ,  C07D409/04 ,  C07D409/12 ,  C07D409/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/12

摘要： This invention is generally directed to the use of Indazole Compounds for treating or preventing diseases associated with protein kinases, including tyrosine kinases, such as proliferative diseases, inflammatory diseases, abnormal angiogenesis and diseases related thereto, atherosclerosis, macular degeneration, diabetes, obesity, pain and others. The methods comprise the administration to a patient in need thereof of an effective amount of an indazole compound that inhibits, modulates or regulates tyrosine kinase signal transduction. Novel indazole compounds or pharmaceutically acceptable salt thereof are presented herein.

摘要翻译： 本发明一般涉及吲唑化合物用于治疗或预防与蛋白激酶相关的疾病，包括酪氨酸激酶，例如增殖性疾病，炎性疾病，异常血管发生及其相关疾病，动脉粥样硬化，黄斑变性，糖尿病，肥胖症，疼痛 和别的。 所述方法包括向有需要的患者施用有效量的抑制，调节或调节酪氨酸激酶信号转导的吲唑化合物。 本文给出了新的吲唑化合物或其药学上可接受的盐。

公开(公告)号：US5520847A

公开(公告)日：1996-05-28

申请号：US247994

申请日：1994-05-24

申请人： Yoshitaka Satoh ,  Hitoshi Toki ,  Fumiaki Kataoka ,  Shigeo Itoh

发明人： Yoshitaka Satoh ,  Hitoshi Toki ,  Fumiaki Kataoka ,  Shigeo Itoh

IPC分类号： C09K11/64 ,  H01J31/15 ,  C09K11/57 ,  C09K11/54

CPC分类号： C09K11/642

摘要： A low-velocity electron excited phosphor having a composition represented by a general formula ZnO.multidot.(Al.sub.x, Ga.sub.l-x).sub.2 O.sub.3 :Mn, wherein X=0.001 to 0.3 mol. A content of Al in the phosphor is set be to within a range between 0.001 mol and 0.3 mol. The range permits a variation in luminance of the phosphor to be within .+-.30% and initial luminance of the phosphor to be significantly increased, resulting in the phosphor being suitable for use for a fluorescent display device.

摘要翻译： 具有由通式ZnO x（Al x，Gal-x）2 O 3：Mn表示的组成的低速电子激发的荧光体，其中X = 0.001〜0.3mol。 荧光体中的Al含量设定在0.001mol〜0.3mol的范围内。 该范围允许荧光体的亮度变化在±30％以内，并且荧光体的初始亮度显着增加，导致荧光体适合用于荧光显示装置。

公开(公告)号：US20140106140A1

公开(公告)日：2014-04-17

申请号：US14004731

申请日：2012-03-26

申请人： Takeo Ikeda ,  Hiroaki Matsubara ,  Mitsuru Kitada ,  Yoshitaka Satoh ,  Kiyomi Nagano

发明人： Takeo Ikeda ,  Hiroaki Matsubara ,  Mitsuru Kitada ,  Yoshitaka Satoh ,  Kiyomi Nagano

IPC分类号： B41M5/52 ,  B41M7/00

CPC分类号： B41M5/5254 ,  B32B7/12 ,  B32B17/10 ,  B32B27/08 ,  B32B27/308 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B27/40 ,  B32B2250/24 ,  B32B2255/10 ,  B32B2255/26 ,  B32B2307/4026 ,  B32B2307/412 ,  B32B2307/75 ,  B32B2553/00 ,  B41M5/506 ,  B41M5/508 ,  B41M5/5263 ,  B41M5/5281 ,  B41M7/0027 ,  B41M2205/38 ,  Y10T428/24802 ,  Y10T428/24851 ,  Y10T428/24868 ,  Y10T428/31855 ,  Y10T428/31909

摘要： The present invention provides an ink jet recording medium which is capable of uniform coating with an ink-receiving agent without a surface treatment step for a usual plastic film used as a base material, and which, due to excellent adhesion , does not cause the problem of peeling after ink jet printing, and does not cause the problem of ink binning, fading, dropout, or peeling or peeling of an ink-receiving layer and an over-coating layer, and also provides a printed material formed by ink jet printing on the ink jet recording medium. The ink jet recording medium including a first layer containing a polyolefin resin as a main component, a second layer containing an acid-modified olefin resin, and an ink-receiving layer is used, the ink-receiving layer being formed by applying an ink-receiving agent on the second layer after the first and second layers are laminated by a coextrusion laminating method.

摘要翻译： 本发明提供了一种喷墨记录介质，其能够在没有用于作为基材的通常的塑料膜的表面处理步骤的情况下用油墨接收剂均匀地涂布，并且由于优异的粘附性，不会引起问题 在喷墨打印之后剥离，并且不会引起油墨接收层和涂覆层的墨水收集，褪色，脱落或剥离或剥离的问题，并且还提供通过喷墨印刷形成的印刷材料 喷墨记录介质。 使用包括含有聚烯烃树脂作为主要成分的第一层，含有酸改性烯烃树脂的第二层和油墨接收层的喷墨记录介质，油墨接收层通过涂布油墨 - 在第一层和第二层之间通过共挤出层压方法层压第二层上的接收剂。

公开(公告)号：US20130029987A1

公开(公告)日：2013-01-31

申请号：US13451574

申请日：2012-04-20

申请人： Brydon L. Bennett ,  Jan Elsner ,  Paul Erdman ,  Robert Hilgraf ,  Laurie Ann LeBrun ,  Meg McCarrick ,  Mehran F. Moghaddam ,  Mark A. Nagy ,  Stephen Norris ,  David A. Paisner ,  Marianne Sloss ,  William J. Romanow ,  Yoshitaka Satoh ,  Jayashree Tikhe ,  Won Hyung Yoon ,  Mercedes Delgado

发明人： Brydon L. Bennett ,  Jan Elsner ,  Paul Erdman ,  Robert Hilgraf ,  Laurie Ann LeBrun ,  Meg McCarrick ,  Mehran F. Moghaddam ,  Mark A. Nagy ,  Stephen Norris ,  David A. Paisner ,  Marianne Sloss ,  William J. Romanow ,  Yoshitaka Satoh ,  Jayashree Tikhe ,  Won Hyung Yoon ,  Mercedes Delgado

IPC分类号： A61K31/505 ,  C07D405/12 ,  C07D401/12 ,  A61K31/506 ,  C07D405/14 ,  C12N5/071 ,  C07D413/12 ,  A61K31/5377 ,  A61P1/16 ,  A61P3/10 ,  A61P3/00 ,  C07D239/48 ,  C07D403/12

CPC分类号： C07D239/48 ,  A61K31/505 ,  C07D401/04 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12

摘要： Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.