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23 条记录 (耗时 0.033 秒)

    CONTAINER
    1.
    发明申请
    CONTAINER 审中-公开
    容器

    公开(公告)号：US20100219094A1

    公开(公告)日：2010-09-02

    申请号：US12302006

    申请日：2007-05-22

    申请人： Masashi Moteki ,  Minoru Honda ,  Kenji Omori

    发明人： Masashi Moteki ,  Minoru Honda ,  Kenji Omori

    IPC分类号： B65D73/00

    CPC分类号： A61J1/10 ,  A61J1/2024 ,  A61J1/2093 ,  B32B7/05 ,  B32B15/08 ,  B32B27/306 ,  B32B27/32 ,  B32B27/34 ,  B32B27/365 ,  B32B2255/10 ,  B32B2255/20 ,  B32B2255/205 ,  B32B2307/7244 ,  B32B2439/46 ,  B32B2439/80 ,  B32B2535/00 ,  B65D81/24 ,  B65D81/3266

    摘要： A drug container with no need to peel a gas-barrier film or with no need to contain a desiccant, an oxygen absorbent or the like, in which the contents therein can be seen by the naked eyes. The container (10) comprises a front sheet (20) and a rear sheet (22), the front sheet (20) and the rear sheet (22) being fusion-bonded each other so as to form a space (14) therebetween, wherein the front sheet is constituted of a multilayered film having a linear-polyolefin layer as the outermost layer, wherein the rear sheet is constituted of a multilayered film having at least one selected from a group consisting of a metal foil, a vapor-deposited metal layer and a vapor-deposited inorganic layer, and wherein a transparent covering sheet (24) comprising a film having a vapor-deposited metal oxide layer is fusion-bonded to the front sheet so that the entire outer surface of at least a part of the front sheet which forms the space can be covered with the transparent covering sheet (24).

    摘要翻译： 不需要剥离阻气膜的药物容器，也可以不含有通过肉眼可以看到内容物的干燥剂，氧吸收剂等。 容器（10）包括前片（20）和后片（22），前片（20）和后片（22）彼此熔合以在其间形成间隙（14） 其特征在于，所述前片由具有直链状聚烯烃层作为最外层的多层膜构成，所述后片由具有选自金属箔，气相沉积金属 层和气相沉积无机层，并且其中将包含具有气相沉积金属氧化物层的膜的透明覆盖片（24）熔融粘合到前片，使得至少一部分的整个外表面 可以用透明覆盖片（24）覆盖形成空间的前片。

    Medicine bag
    6.
    发明授权
    Medicine bag 有权
    药袋

    公开(公告)号：US07243787B2

    公开(公告)日：2007-07-17

    申请号：US10800885

    申请日：2004-03-15

    申请人： Masanobu Iwasa ,  Minoru Honda ,  Masaki Ikenoue ,  Kenji Omori

    发明人： Masanobu Iwasa ,  Minoru Honda ,  Masaki Ikenoue ,  Kenji Omori

    IPC分类号： B65D25/08

    CPC分类号： A61J1/1412 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1462 ,  A61J1/1487 ,  A61J1/18 ,  A61J1/2024 ,  A61J1/2093 ,  A61J2205/30 ,  B32B1/00

    摘要： A medicine bag, which includes a bag body having a medicine storage chamber that stores a medicine in such a way that the medicine is visually confirmed through a light-transmission portion provided in at least one part of the bag body, the bag body having a weak seal portion that divides the medicine storage chamber into a plurality of division spaces, and the sealing of the weak seal portion adjacent to a specific division space being removed by increasing the internal pressure of that division space, including: a cover sheet which is peelably attached to the bag body; and a requisitely-used portion which is used in the process shortly before the medicine is administered, in which the cover sheet includes: a light-shielding portion which shields from the light the medicine stored in at least one division space by covering a predetermined part of the light-transmission portion; and a continuously-formed portion which is continuously formed in the light-shielding portion and is placed so that the requisitely-used portion is prevented from being used with the cover sheet kept attached.

    摘要翻译： 一种药袋，其具有袋体，所述袋体具有药剂储存室，所述药剂储存室以通过设置在所述袋体的至少一部分的透光部目视确认所述药物的方式存储药物，所述袋体具有 将药剂储存室分割为多个分隔空间的弱密封部，通过增加该分隔空间的内压来除去与特定分隔空间相邻的弱密封部的密封，包括：可剥离的覆盖片 附在袋体上; 以及在药物被施用之前不久使用的必要使用部分，其中所述覆盖片包括：遮光部，其通过覆盖预定部分遮挡光存储在至少一个分割空间中的药物 的光传输部分; 以及连续地形成在遮光部分中的连续形成部分，并且被放置成防止被保护的部分与被保持附着的盖板一起使用。

    Cyclic compounds
    8.
    发明申请
    Cyclic compounds 审中-公开
    环状化合物

    公开(公告)号：US20080027037A1

    公开(公告)日：2008-01-31

    申请号：US11889749

    申请日：2007-08-16

    申请人： Koichiro Yamada ,  Kenji Matsuki ,  Kenji Omori ,  Kohei Kikkawa

    发明人： Koichiro Yamada ,  Kenji Matsuki ,  Kenji Omori ,  Kohei Kikkawa

    IPC分类号： A61K31/495 ,  A61K31/40 ,  A61K31/496 ,  A61K31/497 ,  A61K31/53 ,  A61K31/553 ,  A61P9/00 ,  C07D239/02 ,  C07D401/02 ,  C07D498/14 ,  C07D498/04 ,  C07D413/02 ,  C07D403/02 ,  C07D253/065 ,  C07D207/44 ,  A61P5/00 ,  A61K31/535 ,  A61K31/505 ,  A61K31/4965 ,  A61K31/44

    CPC分类号： C07D401/12 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/56 ,  C07D401/04 ,  C07D401/14 ,  C07D403/04 ,  C07D405/12 ,  C07D405/14 ,  C07D413/04 ,  C07D413/12 ,  C07D413/14 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07F9/65583

    摘要： 1. A cyclic compound of the formula (I) or a pharmacologically acceptable salt thereof, wherein X is ═CH— or ═N—, Y is —NH—, —NR4—, —S—, —O—, —CH═N—, —N═CH—, —N═N—, —CH═CH—, etc., R1 is a lower alkoxy group, an amino group, a heterocyclic ring containing N atom(s), or a hydroxy group substituted by a heterocyclic ring containing N atom(s) (each of which is optionally substituted), R2 is a lower alkylamino group which is optionally substituted by an aryl group, a lower alkoxy group which is optionally substituted by an aryl group, a lower alkoxy group substituted by an aromatic heterocyclic ring containing N atom(s), R3 is an aryl group, a heterocyclic ring containing N atom(s), a lower alkyl group, a lower alkoxy group, a cyclo lower alkoxy group, a hydroxy group substituted by a heterocyclic ring containing N atom(s), or an amino group (each of which is optionally substituted), and R3 and a substituent in Y may be combined to form a lactone ring. The compound of the present invention has excellent selective PDE V inhibitory activity and therefore, is useful as a therapeutic or prophylactic drug for treating various diseases due to functional disorders on cGMP-signaling.

    摘要翻译： 1.式（I）的环状化合物或其药理学上可接受的盐，其中X是-CH-或-N-，Y是-NH-，-NR 4 - ， - S- ，-O - ， - CH-N - ， - N-CH - ， - N - ， - CH-CH-等，R 1是低级烷氧基，氨基， 含有N原子的杂环或被含有N原子（各自任选被取代的）的杂环取代的羟基，R 2是任选地是低级烷基氨基 被芳基取代，任选被芳基取代的低级烷氧基，被含有N原子的芳族杂环取代的低级烷氧基，R 3是芳基， 含有N原子，低级烷基，低级烷氧基，环低级烷氧基，被含有N原子的杂环取代的羟基或氨基的杂环（各自为 任选取代的）和R 3和Y中的取代基可以组合形成 内酯环。 本发明的化合物具有优异的选择性PDE V抑制活性，因此可用作治疗或预防药物，用于治疗由于cGMP信号传导的功能紊乱引起的各种疾病。

    Aromatic nitrogen-containing 6-membered cyclic compounds
    9.
    发明授权
    Aromatic nitrogen-containing 6-membered cyclic compounds 有权
    芳香族含氮6元环状化合物

    公开(公告)号：US06797709B2

    公开(公告)日：2004-09-28

    申请号：US10426884

    申请日：2003-05-01

    申请人： Koichiro Yamada ,  Kenji Matsuki ,  Kenji Omori ,  Kohei Kikkawa

    发明人： Koichiro Yamada ,  Kenji Matsuki ,  Kenji Omori ,  Kohei Kikkawa

    IPC分类号： C07D24110

    CPC分类号： C07D239/48 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D513/04 ,  C07F9/6512 ,  C07F9/65583

    摘要： An aromatic nitrogen-containing 6-membered cyclic compound of the formula (I): wherein Ring A is a substituted or unsubstituted nitrogen-containing heterocyclic group; R1 is a substituted or unsubstituted lower alkyl group, —NH—Q—R3 (R3 is a substituted or unsubstituted nitrogen containing heterocyclic group, and Q is a lower alkylene group or a single bond), or —NH—R4 (R4 is a substituted or unsubstituted cycloalkyl group); R2 is a substituted or unsubstituted aryl group; one of Y and Z is ═CH—, and the other is ═N—, or a pharmaceutically acceptable salt thereof, these compounds exhibiting excellent selective PDE V inhibitory activities, and hence, being useful in the prophylaxis or treatment of penile erectile dysfunction, etc.

    摘要翻译： 式（I）的芳香族含氮6元环状化合物：其中环A是取代或未取代的含氮杂环基; R 1是取代或未取代的低级烷基，-NH-QR 3（R 3是取代或未取代的含氮杂环基，Q是低级亚烷基或单键）或 - NH-R 4（R 4是取代或未取代的环烷基）; R 2是取代或未取代的芳基; Y和Z之一是= CH-，另一个是= N-或其药学上可接受的盐，这些化合物表现出优异的选择性PDE V抑制活性，因此可用于预防或治疗阴茎勃起功能障碍， 等等

    Aromatic nitrogen-containing 6-membered cyclic compounds
    10.
    发明授权
    Aromatic nitrogen-containing 6-membered cyclic compounds 有权
    芳香族含氮6元环状化合物

    公开(公告)号：US06656935B2

    公开(公告)日：2003-12-02

    申请号：US09925892

    申请日：2001-08-10

    申请人： Koichiro Yamada ,  Kenji Matsuki ,  Kenji Omori ,  Kohei Kikkawa

    发明人： Koichiro Yamada ,  Kenji Matsuki ,  Kenji Omori ,  Kohei Kikkawa

    IPC分类号： C07D23948

    CPC分类号： C07D239/48 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  C07D413/04 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D513/04 ,  C07F9/6512 ,  C07F9/65583

    摘要： An aromatic nitrogen-containing 6-membered cyclic compound of the formula (I): wherein Ring A is a substituted or unsubstituted nitrogen-containing heterocyclic group; R1 is a substituted or unsubstituted lower alkyl group, —NH—Q—R3 (R3 is a substituted or unsubstituted nitrogen containing heterocyclic group, and Q is a lower alkylene group or a single bond), or —NH—R4 (R4 is a substituted or unsubstituted cycloalkyl group); R2 is a substituted or unsubstituted aryl group; one of Y and Z is ═CH—, and the other is ═N—, or a pharmaceutically acceptable salt thereof, these compounds exhibiting excellent selective PDE V inhibitory activities, and hence, being useful in the prophylaxis or treatment of penile erectile dysfunction, etc.

    摘要翻译： 式（I）的芳香族含氮6元环状化合物：其中环A是取代或未取代的含氮杂环基; R 1是取代或未取代的低级烷基，-NH-QR 3（R 3是取代或未取代的含氮杂环基，Q是低级亚烷基或单键）或 - NH-R 4（R 4是取代或未取代的环烷基）; R 2是取代或未取代的芳基; Y和Z之一是= CH-，另一个是= N-或其药学上可接受的盐，这些化合物表现出优异的选择性PDE V抑制活性，因此可用于预防或治疗阴茎勃起功能障碍， 等等