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1.发明授权公开(公告)号：US10780410B2
公开(公告)日：2020-09-22
申请号：US15504049
申请日：2015-08-14
发明人： Klavs F. Jensen , Timothy F. Jamison , Allan S. Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
IPC分类号： B01J19/00 , B01J19/18 , A61K31/14 , A61K31/167
摘要： Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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公开(公告)号：US09927038B2
公开(公告)日：2018-03-27
申请号：US14420683
申请日：2013-08-09
发明人： Andrea Adamo , Alexander P. Clayton , Patrick Louis Heider , Nopphon Weeranoppanant , Klavs F. Jensen
CPC分类号： F16K15/14 , B01L3/502723 , B01L3/502738 , B01L2200/0673 , B01L2200/0684 , B01L2300/0681 , B01L2300/0864 , B01L2300/0874 , B01L2400/0487 , B01L2400/0655 , F16K99/0015 , F16K99/0057 , Y10T137/7793 , Y10T137/87249
摘要： Pressure control in fluidic systems is generally described. In some cases, a system comprises a fluid-permeable (e.g., liquid-permeable) medium and a pressure regulator. The medium and the pressure regulator can be positioned between a first fluidic channel and a second fluidic channel. The medium is arranged, in certain cases, such that fluid (e.g., liquid) can be transported from the first fluidic channel, through the medium, and into the second fluidic channel. In certain cases, when a first pressure within the first fluidic channel is below a sum of the permeability pressure differential of the medium with respect to the fluid and a second pressure within the second fluidic channel, the fluid is substantially prevented from being transported through an outlet of the first fluidic channel.
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3.发明申请公开(公告)号：US20200368710A1
公开(公告)日：2020-11-26
申请号：US16988827
申请日：2020-08-10
发明人： Klavs F. Jensen , Timothy F. Jamison , Allan S. Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
摘要： Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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4.发明公开公开(公告)号：US20230201787A1
公开(公告)日：2023-06-29
申请号：US18086487
申请日：2022-12-21
发明人： Klavs F. Jensen , Timothy F. Jamison , Allan Stuart Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
CPC分类号： B01J19/004 , B01J19/0093 , B01J19/18 , B01J2219/00799 , B01J2219/00011 , B01J2219/0004 , B01J2219/00795 , B01J2219/00806 , B01J2219/00813 , B01J2219/00907 , B01J2219/00909 , B01J2219/00918 , B01J2219/00831 , B01J2219/0081 , B01J2219/00833 , B01J2219/00873 , B01J2219/00817 , B01J2219/00822 , B01J2219/00986 , B01J2219/00835 , B01J2219/00889 , B01J2219/00871 , B01J2219/0002 , A61K31/14
摘要： Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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5.发明授权公开(公告)号：US11565230B2
公开(公告)日：2023-01-31
申请号：US16988827
申请日：2020-08-10
发明人： Klavs F. Jensen , Timothy F. Jamison , Allan S. Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
IPC分类号： B01J19/00 , B01J19/18 , A61K31/14 , A61K31/167
摘要： Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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公开(公告)号：US20150285387A1
公开(公告)日：2015-10-08
申请号：US14420683
申请日：2013-08-09
发明人： Andrea Adamo , Alexander P. Clayton , Patrick Louis Heider , Nopphon Weeranoppanant , Klavs F. Jensen
IPC分类号： F16K15/14
CPC分类号： F16K15/14 , B01L3/502723 , B01L3/502738 , B01L2200/0673 , B01L2200/0684 , B01L2300/0681 , B01L2300/0864 , B01L2300/0874 , B01L2400/0487 , B01L2400/0655 , F16K99/0015 , F16K99/0057 , Y10T137/7793 , Y10T137/87249
摘要： Pressure control in fluidic systems is generally described. New trends in chemical synthesis involve the use of continuous reaction schemes, for example, in microfluidic and/or millifluidic devices. In many of these processes, it is often helpful to maintain controlled separation between two liquid phases and/or between a liquid phase and a gas phase. For example, in many processes, liquid-liquid and/or a gas-liquid separations are performed (e.g., between an aqueous and an organic phase)
摘要翻译： 通常描述流体系统中的压力控制。 化学合成的新趋势涉及使用连续反应方案，例如在微流体和/或微流体装置中。 在许多这些方法中，维持两个液相之间和/或在液相和气相之间的受控分离通常是有帮助的。 例如，在许多方法中，进行液 - 液和/或气 - 液分离（例如在水相和有机相之间）
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