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1.
公开(公告)号:US10780410B2
公开(公告)日:2020-09-22
申请号:US15504049
申请日:2015-08-14
Applicant: Massachusetts Institute of Technology
Inventor: Klavs F. Jensen , Timothy F. Jamison , Allan S. Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
IPC: B01J19/00 , B01J19/18 , A61K31/14 , A61K31/167
Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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公开(公告)号:US09169277B2
公开(公告)日:2015-10-27
申请号:US14174301
申请日:2014-02-06
Applicant: Massachusetts Institute of Technology
Inventor: Timothy F. Jamison , Yutaka Ikeuchi
IPC: C07D317/00 , C07F7/18 , C07D317/20 , C07D317/26 , C07D493/20
CPC classification number: C07F7/1804 , C07D317/20 , C07D317/26 , C07D493/20
Abstract: The present invention generally relates to methods for the synthesis of catalysts, including epoxidation catalysts, and related compounds and catalyst compositions. Embodiments described herein may provide efficient processes for providing catalysts (e.g., epoxidation catalysts) in large quantities and using simplified methods.
Abstract translation: 本发明一般涉及合成催化剂的方法,包括环氧化催化剂以及相关化合物和催化剂组合物。 本文描述的实施方案可以提供大量提供催化剂(例如环氧化催化剂)和使用简化方法的有效方法。
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3.
公开(公告)号:US20230201787A1
公开(公告)日:2023-06-29
申请号:US18086487
申请日:2022-12-21
Applicant: Massachusetts Institute of Technology
Inventor: Klavs F. Jensen , Timothy F. Jamison , Allan Stuart Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
CPC classification number: B01J19/004 , B01J19/0093 , B01J19/18 , B01J2219/00799 , B01J2219/00011 , B01J2219/0004 , B01J2219/00795 , B01J2219/00806 , B01J2219/00813 , B01J2219/00907 , B01J2219/00909 , B01J2219/00918 , B01J2219/00831 , B01J2219/0081 , B01J2219/00833 , B01J2219/00873 , B01J2219/00817 , B01J2219/00822 , B01J2219/00986 , B01J2219/00835 , B01J2219/00889 , B01J2219/00871 , B01J2219/0002 , A61K31/14
Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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4.
公开(公告)号:US20190126229A1
公开(公告)日:2019-05-02
申请号:US16098333
申请日:2017-05-02
Applicant: Massachusetts Institute of Technology
Inventor: Andrea Adamo , Dale Arlington Thomas, III , Klavs F. Jensen , Timothy F. Jamison , Aaron A. Bedermann , Kosisochukwu C. Aroh
Abstract: The instant disclosure is related to fluidic distributors, fluidic systems, and associated methods and articles. Certain embodiments are related to fluidic distributors that comprise bays including fluidic connections with relative positions that substantially correspond to each other. In some embodiments, a fluidic distributor may comprise bays with electrical interfaces with relative positions that substantially correspond to each other.
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5.
公开(公告)号:US20130310575A1
公开(公告)日:2013-11-21
申请号:US13826539
申请日:2013-03-14
Applicant: Massachusetts Institute of Technology
Inventor: Trevor Alan Hatton , Timothy F. Jamison , Jennifer Aiden Kozak , Fritz Simeon , Jie Wu
IPC: C07D317/38
CPC classification number: C07D317/38
Abstract: Described herein are inventive methods for synthesis of cyclic carbonates from CO2 and epoxide. In some embodiments, the methods are carried out in the presence of a catalyst comprising an electrophilic halogen. In some embodiments, the methods are carried out in a flow reactor.
Abstract translation: 本文描述了用于从CO 2和环氧化物合成环状碳酸酯的发明方法。 在一些实施方案中,所述方法在包含亲电子卤素的催化剂的存在下进行。 在一些实施方案中,所述方法在流动反应器中进行。
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6.
公开(公告)号:US11565230B2
公开(公告)日:2023-01-31
申请号:US16988827
申请日:2020-08-10
Applicant: Massachusetts Institute of Technology
Inventor: Klavs F. Jensen , Timothy F. Jamison , Allan S. Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
IPC: B01J19/00 , B01J19/18 , A61K31/14 , A61K31/167
Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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公开(公告)号:US20160376293A1
公开(公告)日:2016-12-29
申请号:US15191285
申请日:2016-06-23
Applicant: Massachusetts Institute of Technology
Inventor: Timothy F. Jamison , Eric Alan Standley
CPC classification number: C07F7/188 , B01J31/2273 , B01J31/2295 , B01J31/24 , B01J31/2404 , B01J31/2409 , B01J31/2414 , B01J2231/32 , B01J2231/34 , B01J2531/847 , C07F15/04
Abstract: Described herein are nickel pre-catalysts and related compositions and methods. The nickel pre-catalysts may be activated to form catalysts which may be utilized in organic reactions.
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公开(公告)号:US11185839B2
公开(公告)日:2021-11-30
申请号:US16098333
申请日:2017-05-02
Applicant: Massachusetts Institute of Technology
Inventor: Andrea Adamo , Dale Arlington Thomas, III , Klavs F. Jensen , Timothy F. Jamison , Aaron A. Bedermann , Kosisochukwu C. Aroh
Abstract: The instant disclosure is related to fluidic distributors, fluidic systems, and associated methods and articles. Certain embodiments are related to fluidic distributors that comprise bays including fluidic connections with relative positions that substantially correspond to each other. In some embodiments, a fluidic distributor may comprise bays with electrical interfaces with relative positions that substantially correspond to each other.
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9.
公开(公告)号:US20200368710A1
公开(公告)日:2020-11-26
申请号:US16988827
申请日:2020-08-10
Applicant: Massachusetts Institute of Technology
Inventor: Klavs F. Jensen , Timothy F. Jamison , Allan S. Myerson , Jean-Christophe M. Monbaliu , Mohsen Behnam , Shin Yee Wong , Nopphon Weeranoppanant , Eve Marie Revalor , Torsten Stelzer , Jie Chen , Andrea Adamo , David R. Snead , Ping Zhang
Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
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10.
公开(公告)号:US09382281B2
公开(公告)日:2016-07-05
申请号:US14535854
申请日:2014-11-07
Applicant: Massachusetts Institute of Technology
Inventor: Timothy F. Jamison , Eric Alan Standley
CPC classification number: C07F7/188 , B01J31/2273 , B01J31/2295 , B01J31/24 , B01J31/2404 , B01J31/2409 , B01J31/2414 , B01J2231/32 , B01J2231/34 , B01J2531/847 , C07F15/04
Abstract: Described herein are nickel pre-catalysts and related compositions and methods. The nickel pre-catalysts may be activated to form catalysts which may be utilized in organic reactions.
Abstract translation: 本文描述的是镍预催化剂和相关组合物和方法。 镍预催化剂可以被活化以形成可用于有机反应的催化剂。
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