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1.发明授权公开(公告)号：US09226736B2
公开(公告)日：2016-01-05
申请号：US12793030
申请日：2010-06-03
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
摘要翻译： 描述了可用于治疗瘘的装置，方法和系统，并且在某些实施例中，具有延伸进入消化道的开口的那些，诸如肛门直肠瘘。 说明性地，可以通过将体积结构置于瘘的主要开口内来治疗肛门直肠瘘。 在某些实施方案中，体积构造可以包括经加工以形成基本上单体的卷状可重塑材料。 有益的这种可重塑材料可以包括胶原细胞外基质材料，如小肠粘膜下层。
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2.发明申请System and Method to Adaptively Pre-Compensate for Target Material Push-Out to Optimize Extreme Ultraviolet Light Production 有权适应性预补偿目标材料推出以优化极紫外光生产的系统和方法公开(公告)号：US20140091239A1
公开(公告)日：2014-04-03
申请号：US13631645
申请日：2012-09-28
IPC分类号： G01J3/10
CPC分类号： G03F7/70033 , B05B17/00 , H05G2/006 , H05G2/008 , H05H1/24
摘要： Energy output from a laser-produced plasma (LPP) extreme ultraviolet light (EUV) system varies based on how well the laser beam is focused on droplets of target material to generate plasma at a primary focal spot. Maintaining droplets at the primary focal spot during burst firing is difficult because generated plasma from preceding droplets push succeeding droplets out of the primary focal spot Current droplet-to-droplet feedback control to re-align droplets to the primary focal spot is relatively slow. The system and method described herein adaptively pre-compensate for droplet push-out by directing droplets to a target position that is offset from the primary focal spot such that when a droplet is lased, the droplet is pushed by the laser beam into the primary focal spot to generate plasma. Over time, the EUV system learns to maintain real-time alignment of droplet position so plasma is generated consistently within the primary focal spot.
摘要翻译： 来自激光产生的等离子体（LPP）极紫外光（EUV）系统的能量输出基于激光束聚焦在目标材料的液滴上以在主要焦点产生等离子体的程度而变化。 在爆发发射期间，在主要焦点处保持液滴是困难的，因为来自前一个液滴的产生的等离子体将后续的液滴推出主要焦点。电流液滴到液滴反馈控制将液滴重新对准主要焦点是相对较慢的。 本文所述的系统和方法通过将液滴引导到偏离主要焦点的目标位置来自适应地预补偿液滴推出，使得当液滴被照射时，液滴被激光束推动到主要焦点 点产生等离子体。 随着时间的推移，EUV系统学会保持液滴位置的实时对准，从而在主焦点内始终产生等离子体。
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公开(公告)号：US08295316B2
公开(公告)日：2012-10-23
申请号：US12730506
申请日：2010-03-24
申请人： Robert P. Akins , Richard L. Sandstrom , Daniel J. W. Brown , Matthew R. Graham , Kevin W. Zhang , Patrick L. Nelissen
发明人： Robert P. Akins , Richard L. Sandstrom , Daniel J. W. Brown , Matthew R. Graham , Kevin W. Zhang , Patrick L. Nelissen
IPC分类号： H01S3/13
CPC分类号： H01S3/0014 , G03F7/70025 , G03F7/70533 , G03F7/70975 , H01S3/134 , H01S3/225
摘要： A laser light source experiencing an EOL condition, which might otherwise cause an unscheduled shutdown, is instead operated in a diminished capacity in one or more predetermined or calculated increments. Operating in such diminished capacity continues until the laser system can undergo appropriate maintenance either during a regularly scheduled shutdown or a newly scheduled shutdown. In the meantime, the diminished capacity of the laser system is accommodated by the utilization tool, as appropriate.
摘要翻译： 经历EOL状态的激光光源（否则可能导致非计划关机）反而以一个或多个预定或计算的增量以减小的容量运行。 在这种减少的能力下运行，直到激光系统在定期关机或新计划停机期间才能进行适当的维护。 同时，适当的情况下，利用工具可以适应激光系统的能力下降。
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公开(公告)号：US09456813B2
公开(公告)日：2016-10-04
申请号：US13437169
申请日：2012-04-02
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
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5.发明授权System and method to adaptively pre-compensate for target material push-out to optimize extreme ultraviolet light production 有权系统和方法适应性地预补偿目标材料推出，以优化极紫外光生产公开(公告)号：US09238243B2
公开(公告)日：2016-01-19
申请号：US13631645
申请日：2012-09-28
CPC分类号： G03F7/70033 , B05B17/00 , H05G2/006 , H05G2/008 , H05H1/24
摘要： Energy output from a laser-produced plasma (LPP) extreme ultraviolet light (EUV) system varies based on how well the laser beam is focused on droplets of target material to generate plasma at a primary focal spot. Maintaining droplets at the primary focal spot during burst firing is difficult because generated plasma from preceding droplets push succeeding droplets out of the primary focal spot. Current droplet-to-droplet feedback control to re-align droplets to the primary focal spot is relatively slow. The system and method described herein adaptively pre-compensate for droplet push-out by directing droplets to a target position that is offset from the primary focal spot such that when a droplet is lased, the droplet is pushed by the laser beam into the primary focal spot to generate plasma. Over time, the EUV system learns to maintain real-time alignment of droplet position so plasma is generated consistently within the primary focal spot.
摘要翻译： 来自激光产生的等离子体（LPP）极紫外光（EUV）系统的能量输出基于激光束聚焦在目标材料的液滴上以在主要焦点产生等离子体的程度而变化。 在爆发射击过程中，在主焦点处保持液滴是困难的，因为来自前面的液滴的所产生的等离子体将后续的液滴推出主焦点。 将液滴重新对准主要焦点的当前液滴到液滴的反馈控制相对较慢。 本文所述的系统和方法通过将液滴引导到偏离主要焦点的目标位置来自适应地预补偿液滴推出，使得当液滴被照射时，液滴被激光束推动到主要焦点 点产生等离子体。 随着时间的推移，EUV系统学会保持液滴位置的实时对准，从而在主焦点内始终产生等离子体。
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6.发明申请公开(公告)号：US20120191216A1
公开(公告)日：2012-07-26
申请号：US13437169
申请日：2012-04-02
IPC分类号： A61F2/02
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
摘要翻译： 描述了可用于治疗瘘的装置，方法和系统，并且在某些实施例中，具有延伸进入消化道的开口的那些，诸如肛门直肠瘘。 说明性地，可以通过将体积结构置于瘘的主要开口内来治疗肛门直肠瘘。 在某些实施方案中，体积构造可以包括经加工以形成基本上单体的卷状可重塑材料。 有益的这种可重塑材料可以包括胶原细胞外基质材料，如小肠粘膜下层。
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7.发明申请公开(公告)号：US20100241162A1
公开(公告)日：2010-09-23
申请号：US12793030
申请日：2010-06-03
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
摘要翻译： 描述了可用于治疗瘘的装置，方法和系统，并且在某些实施例中，具有延伸进入消化道的开口的那些，诸如肛门直肠瘘。 说明性地，可以通过将体积结构置于瘘的主要开口内来治疗肛门直肠瘘。 在某些实施方案中，体积构造可以包括经加工以形成基本上单体的卷状可重塑材料。 有益的这种可重塑材料可以包括胶原细胞外基质材料，如小肠粘膜下层。
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公开(公告)号：USD800222S1
公开(公告)日：2017-10-17
申请号：US29525428
申请日：2015-04-29
申请人： Matthew R. Graham
设计人： Matthew R. Graham
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公开(公告)号：US20110235663A1
公开(公告)日：2011-09-29
申请号：US12730506
申请日：2010-03-24
申请人： Robert P. Akins , Richard L. Sandstrom , Daniel J.W. Brown , Matthew R. Graham , Kevin W. Zhang , Patrick L. Nelissen
发明人： Robert P. Akins , Richard L. Sandstrom , Daniel J.W. Brown , Matthew R. Graham , Kevin W. Zhang , Patrick L. Nelissen
IPC分类号： H01S3/10
CPC分类号： H01S3/0014 , G03F7/70025 , G03F7/70533 , G03F7/70975 , H01S3/134 , H01S3/225
摘要： A laser light source experiencing an EOL condition, which might otherwise cause an unscheduled shutdown, is instead operated in a diminished capacity in one or more predetermined or calculated increments. Operating in such diminished capacity continues until the laser system can undergo appropriate maintenance either during a regularly scheduled shutdown or a newly scheduled shutdown. In the meantime, the diminished capacity of the laser system is accommodated by the utilization tool, as appropriate.
摘要翻译： 经历EOL状态的激光光源（否则可能导致非计划关机）反而以一个或多个预定或计算的增量以减小的容量运行。 在这种减少的能力下运行，直到激光系统在定期关机或新计划停机期间才能进行适当的维护。 同时，适当的情况下，利用工具可以适应激光系统的能力下降。
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10.发明授权Medical graft products with differing regions and methods and systems for producing the same 有权具有不同区域的医疗移植物产品及其制造方法和系统公开(公告)号：US07959554B2
公开(公告)日：2011-06-14
申请号：US11523450
申请日：2006-09-19
IPC分类号： A61F2/04
CPC分类号： A61L27/3691 , A61F2/0045 , A61F2/0063 , A61F2250/0014 , A61F2250/0039 , A61L27/3629 , A61L27/3633 , A61L27/50 , A61L27/56 , A61L2430/22 , A61L2430/40 , Y10S623/901 , Y10S623/917
摘要： Described are methods and systems for drying remodelable materials, such that selective regions of the remodelable materials have differing properties. Also described are medical graft products having selective regions of differing material properties. Advantageous remodelable materials include collagenous extracellular matrix material, such as small intestine submucosa.
摘要翻译： 描述了用于干燥可重塑材料的方法和系统，使得可重塑材料的选择性区域具有不同的性质。 还描述了具有不同材料性质的选择性区域的医用移植产品。 有益的可重塑材料包括胶原细胞外基质材料，如小肠粘膜下层。
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