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公开(公告)号：US08423157B2
公开(公告)日：2013-04-16
申请号：US13114898
申请日：2011-05-24
CPC分类号： A61N1/0556 , A61N1/0558
摘要： A stimulation system is disclosed that may include a stimulator unit coupled to electrode contacts on a cuff. In one embodiment, the cuff may be placed at least partially around a nerve. The stimulation system may include at least two electrode contacts disposed on the cuff such that a distance between the at least two electrode contacts various along a length of the electrode contacts. In another embodiment, a plurality of electrode contacts are disposed on the cuff such that distances between at least one electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the at least one electrode contact are different. The stimulator unit may also be implantable.
摘要翻译： 公开了一种刺激系统，其可以包括耦合到袖带上的电极接触件的刺激器单元。 在一个实施例中，袖带可以至少部分地放置在神经周围。 刺激系统可以包括布置在袖带上的至少两个电极触点，使得至少两个电极触点之间的距离沿着电极触点的长度不同。 在另一个实施例中，多个电极触点设置在袖带上，使得多个电极触点内的至少一个电极触点与紧邻至少一个电极触点的每个电极接触之间的距离是不同的。 刺激器单元也可以是可植入的。
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公开(公告)号：US07974706B2
公开(公告)日：2011-07-05
申请号：US11393991
申请日：2006-03-30
CPC分类号： A61N1/0556 , A61N1/0558
摘要： A stimulation system is disclosed that may include a stimulator unit coupled to electrode contacts on a cuff. In one embodiment, the cuff may be placed at least partially around a nerve. The stimulation system may include at least two electrode contacts disposed on the cuff such that a distance between the at least two electrode contacts various along a length of the electrode contacts. In another embodiment, a plurality of electrode contacts are disposed on the cuff such that distances between at least one electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the at least one electrode contact are different. The stimulator unit may also be implantable.
摘要翻译： 公开了一种刺激系统，其可以包括耦合到袖带上的电极接触件的刺激器单元。 在一个实施例中，袖带可以至少部分地放置在神经周围。 刺激系统可以包括布置在袖带上的至少两个电极触点，使得至少两个电极触点之间的距离沿着电极触点的长度不同。 在另一个实施例中，多个电极触点设置在袖带上，使得多个电极触点内的至少一个电极触点与紧邻至少一个电极触点的每个电极接触之间的距离是不同的。 刺激器单元也可以是可植入的。
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3.发明授权公开(公告)号：US09216282B1
公开(公告)日：2015-12-22
申请号：US11855033
申请日：2007-09-13
IPC分类号： A61N1/05
CPC分类号： A61N1/0553 , A61N1/36185
摘要： A paddle lead can include a plurality of first electrodes disposed entirely on a first major surface of the lead body and a plurality of second electrodes disposed entirely on a second major surface of the lead body. A paddle lead may include a plurality of electrodes in at least one column on a paddle body and a strip electrode disposed on the paddle body. A lead may include a lead body with an ellipse-like cross-section and a plurality of electrodes disposed circumferentially around the lead body and proximate to a distal end of the lead body.
摘要翻译： 桨引线可以包括整体设置在引线主体的第一主表面上的多个第一电极和完全设置在引线主体的第二主表面上的多个第二电极。 桨引线可以包括在桨体上的至少一个柱中的多个电极和设置在桨体上的带状电极。 引线可以包括具有椭圆形横截面的引线主体和围绕引线主体并且靠近引线主体的远端周向设置的多个电极。
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公开(公告)号：US20110224744A1
公开(公告)日：2011-09-15
申请号：US13114898
申请日：2011-05-24
IPC分类号： A61N1/36
CPC分类号： A61N1/0556 , A61N1/0558
摘要： A stimulation system is disclosed that may include a stimulator unit coupled to electrode contacts on a cuff. In one embodiment, the cuff may be placed at least partially around a nerve. The stimulation system may include at least two electrode contacts disposed on the cuff such that a distance between the at least two electrode contacts various along a length of the electrode contacts. In another embodiment, a plurality of electrode contacts are disposed on the cuff such that distances between at least one electrode contact within the plurality of electrode contacts and each electrode contact immediately adjacent to the at least one electrode contact are different. The stimulator unit may also be implantable.
摘要翻译： 公开了一种刺激系统，其可以包括耦合到袖带上的电极接触件的刺激器单元。 在一个实施例中，袖带可以至少部分地放置在神经周围。 刺激系统可以包括布置在袖带上的至少两个电极触点，使得至少两个电极触点之间的距离沿着电极触点的长度不同。 在另一个实施例中，多个电极触点设置在袖带上，使得多个电极触点内的至少一个电极触点与紧邻至少一个电极触点的每个电极接触之间的距离是不同的。 刺激器单元也可以是可植入的。
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公开(公告)号：US09393421B2
公开(公告)日：2016-07-19
申请号：US12836440
申请日：2010-07-14
CPC分类号： A61N1/36146 , A61N1/36103 , A61N1/36107 , A61N1/37247 , A61N1/37264
摘要： Systems of techniques for controlling charge flow during the electrical stimulation of tissue. In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the stimulation pulse in a manner such that an amount of charge delivered to the tissue during the stimulation pulse accords with the charge setting.
摘要翻译： 在电刺激组织期间控制电荷流动的技术系统。 一方面，一种方法包括接收描述在电刺激组织的刺激脉冲期间流动的电荷量的电荷设置，以及产生和递送刺激脉冲，使得递送到组织的电荷量 在刺激脉冲期间符合充电设置。
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6.发明授权公开(公告)号：US09327069B2
公开(公告)日：2016-05-03
申请号：US11393565
申请日：2006-03-29
CPC分类号： A61M5/14276 , A61M2210/0693 , A61N1/0529 , A61N1/0531 , A61N1/0534 , A61N1/3605 , A61N1/36082 , A61N1/37205
摘要： Methods of treating a medical condition include applying at least one stimulus to a stimulation site within the brain of a patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to promote neural remodeling within the brain of the patient. Systems for treating a medical condition include an implantable stimulator configured to apply at least one stimulus to a stimulation site within the brain of a patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to promote neural remodeling within the brain of the patient.
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7.发明授权Methods and systems for treating autism by decreasing neural activity within the brain 有权通过减少脑内的神经活动来治疗自闭症的方法和系统公开(公告)号：US09095713B2
公开(公告)日：2015-08-04
申请号：US11478827
申请日：2006-06-30
IPC分类号： A61B5/0402 , A61N1/36 , A61M5/142 , A61N1/05
CPC分类号： A61N1/36082 , A61M5/14276 , A61M2210/0693 , A61N1/0531 , A61N1/0534
摘要： Methods of treating autism include applying at least one stimulus to a stimulation site within the brain of a patient with an implanted stimulator in accordance with one or more stimulation parameters. The stimulus is configured to decrease neural activity within at least a portion of the brain to treat autism. Systems for treating autism include a stimulator configured to apply at least one stimulus to a stimulation site within the brain of a patient in accordance with one or more stimulation parameters. The stimulus is configured to decrease neural activity within at least a portion of the brain to treat autism.
摘要翻译： 治疗自闭症的方法包括根据一个或多个刺激参数用植入的刺激器将至少一种刺激施加到患者脑内的刺激部位。 刺激被配置为减少至少一部分脑内的神经活动以治疗自闭症。 用于治疗自闭症的系统包括刺激器，其被配置为根据一个或多个刺激参数将至少一个刺激应用于患者脑内的刺激部位。 刺激被配置为减少至少一部分脑内的神经活动以治疗自闭症。
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8.发明授权公开(公告)号：US08626297B2
公开(公告)日：2014-01-07
申请号：US12233810
申请日：2008-09-19
申请人： Kristen Jaax , Rafael Carbunaru , Mun Pook Lui , Todd K. Whitehurst , Andrew DiGiore , Brett Daniel Schleicher , Gregory Baldwin , Michael A. Moffitt , Jeffery Van Funderburk , Jim Makous
发明人： Kristen Jaax , Rafael Carbunaru , Mun Pook Lui , Todd K. Whitehurst , Andrew DiGiore , Brett Daniel Schleicher , Gregory Baldwin , Michael A. Moffitt , Jeffery Van Funderburk , Jim Makous
IPC分类号： A61N1/378
CPC分类号： A61N1/3787 , H02J7/025 , H02J7/047 , H02J50/10
摘要： Apparatus and methods for charging an implanted medical device.
摘要翻译： 用于对植入的医疗装置充电的装置和方法。
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9.发明授权Implantable microstimulators and methods for unidirectional propagation of action potentials 失效可植入的微型激励器和动作电位单向传播的方法公开(公告)号：US08548604B2
公开(公告)日：2013-10-01
申请号：US12960722
申请日：2010-12-06
申请人： Todd K. Whitehurst , Rafael Carbunaru , James P. McGivern , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley , Janusz A. Kuzma
发明人： Todd K. Whitehurst , Rafael Carbunaru , James P. McGivern , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley , Janusz A. Kuzma
IPC分类号： A61N1/05
CPC分类号： A61N1/37252 , A61N1/05 , A61N1/0556 , A61N1/36071 , A61N1/37205 , A61N1/37217 , A61N1/37288
摘要： Miniature implantable stimulators (i.e., microstimulators) are capable of producing unidirectionally propagating action potentials (UPAPs). The methods and configurations described may, for instance, arrest action potentials traveling in one direction, arrest action potentials of small diameters nerve fibers, arrest action potentials of large diameter nerve fibers. These methods and systems may limit side effects of bidirectional and/or less targeted stimulation.
摘要翻译： 微型植入式刺激器（即微型刺激器）能够产生单向传播动作电位（UPAP）。 所描述的方法和结构可以例如阻止在一个方向上行进的动作电位，阻止小直径神经纤维的动作电位，阻止大直径神经纤维的动作电位。 这些方法和系统可以限制双向和/或较少靶向刺激的副作用。
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10.发明授权公开(公告)号：US08401654B1
公开(公告)日：2013-03-19
申请号：US11479487
申请日：2006-06-30
IPC分类号： A61N1/00
CPC分类号： A61N1/36103 , A61M5/14276 , A61M2210/0693 , A61N1/0529 , A61N1/0551 , A61N1/36082 , A61N1/36139 , A61N1/36171 , A61N1/37205 , A61N1/37288
摘要： Methods of treating one or more effects of deafferentation within a patient include applying at least one stimulus to a stimulation site within the patient with an implanted stimulator in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat one or more effects of deafferentation. Systems for treating one or more effects of deafferentation within a patient include a stimulator configured to apply at least one stimulus to a stimulation site within the patient in accordance with one or more stimulation parameters. The at least one stimulus is configured to treat one or more effects of deafferentation.
摘要翻译： 治疗患者中一种或多种传入影响的方法包括根据一个或多个刺激参数，使用植入的刺激器将至少一种刺激应用于患者内的刺激部位。 所述至少一个刺激被配置为处理一种或多种传递的影响。 用于治疗患者内一种或多种传入影响的系统包括：刺激器，其构造成根据一个或多个刺激参数将至少一种刺激施加到患者内的刺激部位。 所述至少一个刺激被配置为处理一种或多种传递的影响。
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