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    CONTROLLING CHARGE FLOW IN THE ELECTRICAL STIMULATION OF TISSUE
    2.
    发明申请
    CONTROLLING CHARGE FLOW IN THE ELECTRICAL STIMULATION OF TISSUE 审中-公开
    控制组织电刺激中的电荷流动

    公开(公告)号：US20100280575A1

    公开(公告)日：2010-11-04

    申请号：US12836440

    申请日：2010-07-14

    申请人： Rafael Carbunaru ,  Kelly H. McClure ,  Jordi Parramon

    发明人： Rafael Carbunaru ,  Kelly H. McClure ,  Jordi Parramon

    IPC分类号： A61N1/08 ,  A61N1/36

    CPC分类号： A61N1/36146 ,  A61N1/36103 ,  A61N1/36107 ,  A61N1/37247 ,  A61N1/37264

    摘要： Systems of techniques for controlling charge flow during the electrical stimulation of tissue. In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the stimulation pulse in a manner such that an amount of charge delivered to the tissue during the stimulation pulse accords with the charge setting.

    摘要翻译： 在电刺激组织期间控制电荷流动的技术系统。 一方面，一种方法包括接收描述在电刺激组织的刺激脉冲期间流动的电荷量的电荷设置，以及产生和递送刺激脉冲，使得递送到组织的电荷量 在刺激脉冲期间符合充电设置。

    Controlling charge flow in the electrical stimulation of tissue
    3.
    发明授权
    Controlling charge flow in the electrical stimulation of tissue 有权
    控制电刺激组织中的电荷流

    公开(公告)号：US07801600B1

    公开(公告)日：2010-09-21

    申请号：US11139296

    申请日：2005-05-26

    申请人： Rafael Carbunaru ,  Kelly H. McClure ,  Jordi Parramon

    发明人： Rafael Carbunaru ,  Kelly H. McClure ,  Jordi Parramon

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36146 ,  A61N1/36103 ,  A61N1/36107 ,  A61N1/37247 ,  A61N1/37264

    摘要： Systems of techniques for controlling charge flow during the electrical stimulation of tissue. In one aspect, a method includes receiving a charge setting describing an amount of charge that is to flow during a stimulation pulse that electrically stimulates a tissue, and generating and delivering the stimulation pulse in a manner such that an amount of charge delivered to the tissue during the stimulation pulse accords with the charge setting.

    摘要翻译： 在电刺激组织期间控制电荷流动的技术系统。 一方面，一种方法包括接收描述在电刺激组织的刺激脉冲期间流动的电荷量的电荷设置，以及产生和递送刺激脉冲，使得递送到组织的电荷量 在刺激脉冲期间符合充电设置。

    Current Steering for an Implantable Stimulator Device Involving Fractionalized Stimulation Pulses
    5.
    发明申请
    Current Steering for an Implantable Stimulator Device Involving Fractionalized Stimulation Pulses 有权
    用于涉及分数化刺激脉冲的可植入刺激装置的当前转向

    公开(公告)号：US20100262210A1

    公开(公告)日：2010-10-14

    申请号：US12824663

    申请日：2010-06-28

    申请人： Jordi Parramon ,  Rafael Carbunaru ,  Matt I. Haller

    发明人： Jordi Parramon ,  Rafael Carbunaru ,  Matt I. Haller

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36171 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/36 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/36178 ,  A61N1/37235

    摘要： A method for configuring stimulation pulses in an implantable stimulator device having a plurality of electrodes is disclosed, which method is particularly useful in adjusting the electrodes by current steering during initialization of the device. In one aspect, a set of ideal pulses for patient therapy is determined, in which at least two of the ideal pulses are of the same polarity and are intended to be simultaneous applied to corresponding electrodes on the implantable stimulator device during an initial duration. These pulses are reconstructed into fractionalized pulses, each comprised of pulse portions. The fractionalized pulses are applied to the corresponding electrodes on the device during a final duration, but the pulse portions of the fractionalized pulses are not simultaneously applied during the final duration.

    摘要翻译： 公开了一种用于在具有多个电极的可植入刺激器装置中配置刺激脉冲的方法，该方法在装置的初始化期间通过电流转向来调节电极特别有用。 在一个方面，确定用于患者治疗的一组理想脉冲，其中至少两个理想脉冲具有相同的极性并且旨在在初始持续时间期间同时施加到可植入刺激器装置上的对应电极。 这些脉冲被重建成分数脉冲，每个脉冲包括脉冲部分。 分数脉冲在最后的持续时间内施加到器件上的对应电极，但分数脉冲的脉冲部分在最后的持续时间内不被同时施加。

    Efficient external charger for an implantable medical device optimized for fast charging and constrained by an implant power dissipation limit
    6.
    发明授权
    Efficient external charger for an implantable medical device optimized for fast charging and constrained by an implant power dissipation limit 有权
    用于可植入医疗设备的高效外部充电器，针对快速充电而优化，并受到植入物功率限制的限制

    公开(公告)号：US08744592B2

    公开(公告)日：2014-06-03

    申请号：US12575733

    申请日：2009-10-08

    申请人： Rafael Carbunaru ,  Jordi Parramon ,  Robert Ozawa ,  Jess Shi ,  Joey Chen ,  Md. Mizanur Rahman

    发明人： Rafael Carbunaru ,  Jordi Parramon ,  Robert Ozawa ,  Jess Shi ,  Joey Chen ,  Md. Mizanur Rahman

    IPC分类号： A61N1/00 ,  H02J7/00 ,  A61N1/378 ,  A61N1/372 ,  A61N1/36

    CPC分类号： A61N1/3787 ,  A61N1/3605 ,  A61N1/37205 ,  A61N1/37217

    摘要： An improved external charger for a battery in an implantable medical device (implant), and technique for charging the battery using such improved external charger, is disclosed. In one example, simulation data is used to model the power dissipation of the charging circuitry in the implant at varying levels of implant power. A power dissipation limit is chosen to constrain the charging circuitry from producing an inordinate amount of heat to the tissue surrounding the implant, and duty cycles are determined for the various levels of input intensities to ensure that the power limit is not exceeded. A maximum simulated average battery current determines the optimal (i.e., quickest) battery charging current, and at least an optimal value for a parameter indicative of that current, for example, the voltage across the battery charging circuitry, is determined and stored in the external charger. During charging, the actual value for that parameter is reported from the implant to the external charger, which in turn adjusts the intensity and/or duty cycle of the magnetic charging field consistent with the simulation to ensure that charging is as fast as possible, while still not exceeding the power dissipation limit.

    摘要翻译： 公开了用于可植入医疗装置（植入物）中的电池的改进的外部充电器以及使用这种改进的外部充电器对电池充电的技术。 在一个示例中，模拟数据用于以不同的植入功率水平对植入物中的充电电路的功率耗散进行建模。 选择功率耗散极限以限制充电电路对植入物周围的组织产生过量的热量，并且针对各种输入强度级别确定占空比以确保不超过功率限制。 最大模拟平均电池电流确定最佳（即最快）电池充电电流，并且至少确定表示该电流的参数（例如，电池充电电路两端的电压）的最佳值，并将其存储在外部 充电器。 在充电期间，该参数的实际值从注入到外部充电器报告，外部充电器依次调整充电场的强度和/或占空比，与模拟一致，以确保充电尽可能快，同时 仍然不超过功耗限制。

    Fractionalized stimulation pulses in an implantable stimulator device
    9.
    发明授权
    Fractionalized stimulation pulses in an implantable stimulator device 有权
    可植入刺激装置中的分数化刺激脉冲

    公开(公告)号：US09289610B2

    公开(公告)日：2016-03-22

    申请号：US13595746

    申请日：2012-08-27

    申请人： Jordi Parramon ,  Rafael Carbunaru ,  Matt I. Haller

    发明人： Jordi Parramon ,  Rafael Carbunaru ,  Matt I. Haller

    IPC分类号： A61N1/36 ,  A61N1/372 ,  A61N1/05

    CPC分类号： A61N1/36171 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/36 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36175 ,  A61N1/36178 ,  A61N1/37235

    摘要： A method for configuring stimulation pulses in an implantable stimulator device having a plurality of electrodes is disclosed, which method is particularly useful in adjusting the electrodes by current steering during initialization of the device. In one aspect, a set of ideal pulses for patient therapy is determined, in which at least two of the ideal pulses are of the same polarity and are intended to be simultaneous applied to corresponding electrodes on the implantable stimulator device during an initial duration. These pulses are reconstructed into fractionalized pulses, each comprised of pulse portions. The fractionalized pulses are applied to the corresponding electrodes on the device during a final duration, but the pulse portions of the fractionalized pulses are not simultaneously applied during the final duration.

    摘要翻译： 公开了一种用于在具有多个电极的可植入刺激器装置中配置刺激脉冲的方法，该方法在装置的初始化期间通过电流转向来调节电极特别有用。 在一个方面，确定用于患者治疗的一组理想脉冲，其中至少两个理想脉冲具有相同的极性并且旨在在初始持续时间期间同时施加到可植入刺激器装置上的对应电极。 这些脉冲被重建成分数脉冲，每个脉冲包括脉冲部分。 分数脉冲在最后的持续时间内施加到器件上的对应电极，但分数脉冲的脉冲部分在最后的持续时间内不被同时施加。

    Power Circuitry for an Implantable Medical Device Using a DC-DC Converter
    10.
    发明申请
    Power Circuitry for an Implantable Medical Device Using a DC-DC Converter 审中-公开
    使用DC-DC转换器的可植入医疗设备的功率电路

    公开(公告)号：US20110276110A1

    公开(公告)日：2011-11-10

    申请号：US13086549

    申请日：2011-04-14

    申请人： Todd Whitehurst ,  Rafael Carbunaru ,  Jordi Parramon

    发明人： Todd Whitehurst ,  Rafael Carbunaru ,  Jordi Parramon

    IPC分类号： A61N1/36

    CPC分类号： A61N1/3787 ,  A61N1/37205 ,  H02M3/33592 ,  Y02B70/1475

    摘要： Improved power circuitry for charging a battery in an implantable medical device is disclosed. The improved power circuitry uses a DC-DC converter positioned between the rectifier and the battery in the implant to be charged, and operates to boost the voltage produced by the rectifier to a higher compliance voltage used to charge the battery. Because the rectifier can now produce a smaller DC voltage, the AC voltage preceding the rectifier (the coil voltage), can also be lessened. Lowering the coil voltage reduces the amount of heat generated by the coil, which reduces the overall heat generated by the implant during receipt of a magnetic charging field from an external charger during a charging session, which improves patient safety. Additionally, a reduced coil voltage means that the external charger can reduce the intensity of the magnetic charging field, which also reduces heat generated in the external charger during the charging session.

    摘要翻译： 公开了用于对可植入医疗装置中的电池充电的改进的电源电路。 改进的电源电路使用位于植入物中的整流器和电池之间的DC-DC转换器来充电，并且操作以将由整流器产生的电压升高到用于对电池充电的较高顺应性电压。 因为整流器现在可以产生较小的直流电压，整流器之前的交流电压（线圈电压）也可以减小。 降低线圈电压可减少线圈产生的热量，从而减少了在充电期间从外部充电器接收到磁性充电场期间由植入物产生的总体热量，从而提高了患者的安全性。 此外，减小的线圈电压意味着外部充电器可以减小磁充电场的强度，这也减少了充电阶段期间在外部充电器中产生的热量。