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    Implant and agent delivery device
    7.
    发明申请
    Implant and agent delivery device 审中-公开
    植入物和药剂输送装置

    公开(公告)号：US20050060019A1

    公开(公告)日：2005-03-17

    申请号：US10951735

    申请日：2004-09-28

    申请人： Richard Gambale ,  Stephen Forcucci ,  Michael Weiser ,  Sean Forde

    发明人： Richard Gambale ,  Stephen Forcucci ,  Michael Weiser ,  Sean Forde

    IPC分类号： A61F2/00 ,  A61F2/02 ,  A61F2/06 ,  A61F2/88

    CPC分类号： A61F2/88 ,  A61F2/06 ,  A61F2/2493 ,  A61F2220/0016 ,  A61F2250/0067

    摘要： The present invention provides a system (178) for delivering a therapeutic agent in combination with an implantable device (2) to maximize a therapeutic benefit offered by each. Preferably, the therapeutic agent is contained within a solid matrix form such as a pellet or gel to facilitate its handling and to regulate its rate of dissipation into the tissue after delivery. The implant device (2) is specially configured to receive and retain the matrix but permit blood to interact with the matrix so that the agent can be released to the blood in and around the device and the surrounding tissue. A delivery system (178) comprises an implant delivery device having an obturator (180) capable of piercing the tissue and an agent matrix delivery device (210) to place a matrix form, such as a pellet, into the interior of the implant (2) after it has been implanted. Preferably, the implant delivery device (180) and the matrix delivery device (210) are contained in one apparatus to facilitate delivery of the pellet into the embedded implant. The present invention is useful for treating tissue in any area of the body, especially ischemic tissue experiencing reduced blood flow. The present devices and methods are especially useful for treatment of ischemia of the myocardium. In treatment of the myocardium, the present implant device and matrix combination may be delivered surgically through the epicardium of the heart.

    摘要翻译： 本发明提供了一种用于将治疗剂与可植入装置（2）组合递送以最大化由每个提供的治疗益处的系统（178）。 优选地，治疗剂包含在固体基质形式例如丸粒或凝胶中，以促进其处理并调节其在分娩后向组织中的耗散速率。 植入装置（2）被特别地构造成接收和保持基质，但允许血液与基质相互作用，使得试剂可以释放到装置周围的组织和周围的组织中和周围。 递送系统（178）包括植入物递送装置，其具有能够刺穿组织的闭孔器（180）和药剂矩阵输送装置（210），以将诸如颗粒的矩阵形式放置在植入物（2）的内部 ）植入后。 优选地，植入物递送装置（180）和基质递送装置（210）被包含在一个装置中以便于将颗粒递送到嵌入的植入物中。 本发明可用于治疗身体的任何区域中的组织，特别是经历血流减少的缺血组织。 本发明的装置和方法对于治疗心肌缺血特别有用。 在心肌的治疗中，本发明的植入装置和基质组合可以通过心脏的心外膜手术递送。

    Stent delivery catheter
    10.
    发明申请
    Stent delivery catheter 审中-公开
    支架输送导管

    公开(公告)号：US20050049608A1

    公开(公告)日：2005-03-03

    申请号：US10867428

    申请日：2004-06-14

    申请人： Harold Aznoian ,  Michael Weiser

    发明人： Harold Aznoian ,  Michael Weiser

    IPC分类号： A61F2/04 ,  A61F2/94 ,  A61F11/00 ,  A61M20060101

    CPC分类号： A61F2/95 ,  A61F2/07 ,  A61F2/94 ,  A61F2002/041 ,  A61F2002/9505

    摘要： A delivery device for a biliary stent constructed of thermoplastic material with ridges and valleys formed along the outer surface of the stent that provide a helical, thread-like configuration. The delivery device comprises an external surface that is selectively expandable to engage an interior surface of the tubular stent. Additionally the exterior surface may include ridges and valleys that coincide with ridges and valleys defined by the helical thread extending through the stent in order to provide a more secure engagement with the stent during delivery.

    摘要翻译： 用于由热塑性材料构成的胆管支架的输送装置，所述热塑性材料具有沿支架的外表面形成的具有螺旋状的线状构造的脊和谷。 输送装置包括外表面，其被选择性地可膨胀以接合管状支架的内表面。 此外，外表面可以包括与由延伸穿过支架的螺旋螺纹限定的脊和谷重合的脊和谷，以便在递送期间提供与支架更牢固的接合。