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公开(公告)号：US20060229493A1
公开(公告)日：2006-10-12
申请号：US11399913
申请日：2006-04-06
申请人： Michael Weiser , George Mamo , Michael Chu , Brett Nowlin
发明人： Michael Weiser , George Mamo , Michael Chu , Brett Nowlin
IPC分类号： A61F2/00
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/06109 , A61B2017/0046 , A61B2017/00805 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/0437 , A61B2017/0445 , A61B2017/0464 , A61B2017/0496 , A61B2017/06009 , A61B2017/06042 , A61B2017/06076 , A61B2017/06085 , A61F2/0045 , A61F2002/30062 , A61F2002/3055 , A61F2002/30617 , A61F2210/0004 , A61F2250/0007 , A61F2250/0018 , A61F2250/005 , A61F2250/0087 , A61F2250/0097
摘要： Disclosed are single-incision surgical procedures for treatment of urinary incontinence and/or pelvic floor disorders and related uses, devices, kits, and methods. Implants are also disclosed for use in the exemplary procedures. In certain embodiments, soft tissue anchors are used to anchor the surgical implants to obturator membranes of a patient.
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公开(公告)号：US20060229596A1
公开(公告)日：2006-10-12
申请号：US11400111
申请日：2006-04-06
申请人： Michael Weiser , George Mamo , Michael Chu , Brett Nowlin
发明人： Michael Weiser , George Mamo , Michael Chu , Brett Nowlin
IPC分类号： A61B18/18
CPC分类号： A61B17/00234 , A61B17/0401 , A61B17/06109 , A61B2017/0046 , A61B2017/00805 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/0437 , A61B2017/0445 , A61B2017/0464 , A61B2017/0496 , A61B2017/06009 , A61B2017/06042 , A61B2017/06076 , A61B2017/06085 , A61F2/0045 , A61F2002/30062 , A61F2002/3055 , A61F2002/30617 , A61F2210/0004 , A61F2250/0007 , A61F2250/0018 , A61F2250/005 , A61F2250/0087 , A61F2250/0097
摘要： Disclosed are single-incision surgical procedures for treatment of urinary incontinence and/or pelvic floor disorders and related uses, devices, kits, and methods. Implants are also disclosed for use in the exemplary procedures. In certain embodiments, soft tissue anchors are used to anchor the surgical implants to obturator membranes of a patient.
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3.发明申请公开(公告)号：US20060089525A1
公开(公告)日：2006-04-27
申请号：US11152898
申请日：2005-06-14
申请人： George Mamo , Michael Weiser
发明人： George Mamo , Michael Weiser
IPC分类号： A61F2/00
CPC分类号： A61F2/0045 , A61B17/0401 , A61B17/06066 , A61B17/06109 , A61B2017/00805 , A61B2017/0409 , A61B2017/0412 , A61B2017/0427 , A61B2017/0437 , A61B2017/0445 , A61B2017/0451 , A61B2017/0456 , A61B2017/0459 , A61B2017/0462 , A61B2017/0464 , A61B2017/06042 , A61B2017/06076 , A61F2/0811 , A61F2002/0888 , A61F2002/30062 , A61F2002/3055 , A61F2210/0004 , A61F2220/0016 , A61F2250/0007
摘要： The invention provides, in various embodiments, aspects of soft tissue anchors, adjustable length/tension slings, interconnects between slings and soft tissue anchors, delivery devices and systems for implanting supportive slings, and methods relating to anchoring, adjusting and implanting supportive slings.
摘要翻译： 本发明在各种实施例中提供了软组织锚固件，可调长度/张力吊索，吊索和软组织锚固件之间的互连，用于植入支撑吊索的输送装置和系统以及与支撑吊索的锚定，调整和植入有关的方法的方面。
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公开(公告)号：US20050131391A1
公开(公告)日：2005-06-16
申请号：US10642365
申请日：2003-08-14
申请人： Michael Chu , Alfred Intoccia , Barry Gellman , Joseph Raneri , Michael Weiser , Kenneth Daignault
发明人： Michael Chu , Alfred Intoccia , Barry Gellman , Joseph Raneri , Michael Weiser , Kenneth Daignault
CPC分类号： A61F2/0045 , A61B17/00234 , A61B17/06109 , A61B17/3468 , A61B2017/00805 , A61B2017/06019 , A61B2017/06042 , A61B2017/06052 , A61B2017/06076 , A61B2017/06171 , A61F2002/0072 , A61F2220/0083
摘要： Implant delivery systems are disclosed. In general overview, an exemplary system includes any number of the following: a delivery device, a sling assembly, guide members, and connectors that interconnect the above. Embodiments of all the above components and their combinations are disclosed. Methods of using the above system in suprapubic, prepubic, transvaginal, trans-obturator and other approaches are also disclosed.
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公开(公告)号：US20050131393A1
公开(公告)日：2005-06-16
申请号：US10642397
申请日：2003-08-14
申请人： Michael Chu , Alfred Intoccia , Barry Gellman , Joseph Raneri , Michael Weiser , Armand Morin , Kenneth Daignault
发明人： Michael Chu , Alfred Intoccia , Barry Gellman , Joseph Raneri , Michael Weiser , Armand Morin , Kenneth Daignault
CPC分类号： A61B17/00234 , A61B17/06109 , A61B17/3468 , A61B2017/00805 , A61B2017/06019 , A61B2017/06042 , A61B2017/06052 , A61B2017/06076 , A61B2017/06171 , A61F2/0045
摘要： Implant delivery systems are disclosed. In general overview, an exemplary system includes any number of the following: a delivery device, a sling assembly, guide members, and connectors that interconnect the above. Embodiments of all the above components and their combinations are disclosed. Methods of using the above system in suprapubic, prepubic, transvaginal, trans-obturator and other approaches are also disclosed.
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公开(公告)号：US20130177522A1
公开(公告)日：2013-07-11
申请号：US13515987
申请日：2010-12-15
CPC分类号： A61K47/10 , A61K9/0048 , A61K31/74 , A61K31/79 , A61K33/18 , A61K45/06 , A61K47/08 , A61K47/32 , A61K2300/00
摘要： Disclosed are compositions and methods comprising povidone-iodine and a cooling-effective amount of a chemical agent. The compositions are useful to relieve mild ocular irritation, enhance ocular comfort, and to provide a refreshing effect and improved sensation, when the povidone-iodine solution is applied to the eye.
摘要翻译： 公开了包含聚维酮碘和冷却有效量的化学试剂的组合物和方法。 当将聚维酮碘溶液施用于眼睛时，该组合物可用于缓解轻度眼睛刺激，增强眼睛舒适度，并提供清爽效果和改善的感觉。
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公开(公告)号：US20060009789A1
公开(公告)日：2006-01-12
申请号：US11199955
申请日：2005-08-09
申请人： Richard Gambale , Michael Weiser
发明人： Richard Gambale , Michael Weiser
IPC分类号： A61B17/10
CPC分类号： A61B17/0469 , A61B17/0487 , A61B17/1114 , A61B2017/00349 , A61B2017/00827 , A61B2017/00867 , A61B2017/0409 , A61B2017/0414 , A61B2017/0417 , A61B2017/0443 , A61B2017/0458 , A61B2017/0464 , A61B2017/06171 , A61B2017/0649 , A61B2017/1103 , A61B2017/1142 , A61B2017/308
摘要： The present invention provides tissue capture devices configured to hold tissue in a distorted configuration. The devices may hold precaptured tissue in a distorted configuration or it may change their shape to cause the tissue to become deformed. Some embodiments of the device alter the configuration in areas that remain external to the tissue, while other embodiments change their configuration in areas that are implanted in the tissue. Other embodiments may be mechanically altered to hold the tissue in a distorted shape.
摘要翻译： 本发明提供了构造成将组织保持在变形构型中的组织捕获装置。 这些装置可以将预先组织的组织保持在变形构型中，或者它们可以改变它们的形状以导致组织变形。 该装置的一些实施例在保留在组织外部的区域中改变构造，而其他实施例在植入组织的区域中改变其构型。 可以机械地改变其它实施例以将组织保持在变形形状。
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公开(公告)号：US20050060019A1
公开(公告)日：2005-03-17
申请号：US10951735
申请日：2004-09-28
申请人： Richard Gambale , Stephen Forcucci , Michael Weiser , Sean Forde
发明人： Richard Gambale , Stephen Forcucci , Michael Weiser , Sean Forde
CPC分类号： A61F2/88 , A61F2/06 , A61F2/2493 , A61F2220/0016 , A61F2250/0067
摘要： The present invention provides a system (178) for delivering a therapeutic agent in combination with an implantable device (2) to maximize a therapeutic benefit offered by each. Preferably, the therapeutic agent is contained within a solid matrix form such as a pellet or gel to facilitate its handling and to regulate its rate of dissipation into the tissue after delivery. The implant device (2) is specially configured to receive and retain the matrix but permit blood to interact with the matrix so that the agent can be released to the blood in and around the device and the surrounding tissue. A delivery system (178) comprises an implant delivery device having an obturator (180) capable of piercing the tissue and an agent matrix delivery device (210) to place a matrix form, such as a pellet, into the interior of the implant (2) after it has been implanted. Preferably, the implant delivery device (180) and the matrix delivery device (210) are contained in one apparatus to facilitate delivery of the pellet into the embedded implant. The present invention is useful for treating tissue in any area of the body, especially ischemic tissue experiencing reduced blood flow. The present devices and methods are especially useful for treatment of ischemia of the myocardium. In treatment of the myocardium, the present implant device and matrix combination may be delivered surgically through the epicardium of the heart.
摘要翻译： 本发明提供了一种用于将治疗剂与可植入装置（2）组合递送以最大化由每个提供的治疗益处的系统（178）。 优选地，治疗剂包含在固体基质形式例如丸粒或凝胶中，以促进其处理并调节其在分娩后向组织中的耗散速率。 植入装置（2）被特别地构造成接收和保持基质，但允许血液与基质相互作用，使得试剂可以释放到装置周围的组织和周围的组织中和周围。 递送系统（178）包括植入物递送装置，其具有能够刺穿组织的闭孔器（180）和药剂矩阵输送装置（210），以将诸如颗粒的矩阵形式放置在植入物（2）的内部 ）植入后。 优选地，植入物递送装置（180）和基质递送装置（210）被包含在一个装置中以便于将颗粒递送到嵌入的植入物中。 本发明可用于治疗身体的任何区域中的组织，特别是经历血流减少的缺血组织。 本发明的装置和方法对于治疗心肌缺血特别有用。 在心肌的治疗中，本发明的植入装置和基质组合可以通过心脏的心外膜手术递送。
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9.发明授权
公开(公告)号：US5733325A
公开(公告)日：1998-03-31
申请号：US643527
申请日：1996-05-06
申请人： Timothy Robinson , Michael Weiser , John Carey , Dennis Kujawski
发明人： Timothy Robinson , Michael Weiser , John Carey , Dennis Kujawski
CPC分类号： A61F2/07 , A61F2/95 , A61F2/966 , A61F2/848 , A61F2/89 , A61F2/90 , A61F2/958 , A61F2002/075 , A61F2002/825 , A61F2002/8486 , A61F2002/9522 , A61F2002/9665 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , Y10S623/921
摘要： A graft assembly for securely positioning a graft at a predetermined location across an abdominal aortic aneurysm. The assembly includes a resilient self-expanding anchor that is secured to the graft. The anchor is characterized as being at least as long as the graft, and further as being adapted to be removed or repositioned at any time prior to complete deployment in the patient.
摘要翻译： 一种用于将移植物牢固地定位在穿过腹主动脉瘤的预定位置的移植物组件。 该组件包括固定到移植物上的弹性自膨胀锚。 锚固体的特征在于至少与移植物一样长，并且进一步适于在完全展开患者之前的任何时间被移除或重新定位。
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10.发明申请Otic compositions for the treatment of infections of the internal and external ear in mammals 审中-公开用于治疗哺乳动物内耳和外耳感染的耳用组合物公开(公告)号：US20090263345A1
公开(公告)日：2009-10-22
申请号：US12380463
申请日：2009-02-27
CPC分类号： A61K31/79 , A61K9/0031 , A61K9/0046 , A61K9/06 , A61K31/573 , A61K2300/00
摘要： Disclosed herein compositions including povidone-iodine (PVP-I) useful in the treatment of acute and chronic bacterial, viral and fungal infections of the internal, middle and external ear of mammals, including humans.
摘要翻译： 本文公开了包含聚维酮碘（PVP-1）的组合物，其可用于治疗哺乳动物（包括人）的内部，中部和外部的耳朵的急性和慢性细菌，病毒和真菌感染。
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