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21 条记录 (耗时 0.031 秒)

    MICRONIZED OPIOID COMPOSITIONS, FORMULATIONS AND DOSAGE FORMS AND METHODS OF MAKING SAME
    1.
    发明申请
    MICRONIZED OPIOID COMPOSITIONS, FORMULATIONS AND DOSAGE FORMS AND METHODS OF MAKING SAME 审中-公开
    微量制剂组合物，制剂和剂型及其制备方法

    公开(公告)号：US20090169631A1

    公开(公告)日：2009-07-02

    申请号：US12329318

    申请日：2008-12-05

    申请人： Michael Zamloot ,  Cherng-chyi Fu ,  De-Hwa Chao ,  Andrei Blasko ,  Su ll Yum

    发明人： Michael Zamloot ,  Cherng-chyi Fu ,  De-Hwa Chao ,  Andrei Blasko ,  Su ll Yum

    IPC分类号： A61K9/14 ,  A61P25/04

    CPC分类号： A61K9/14 ,  A61K9/1623 ,  A61K9/1652 ,  A61K31/485

    摘要： Novel compositions, formulations and dosage forms comprising stabilized micronized opioid particles are disclosed. Exemplary opioids include oxycodone, oxymorphone, hydrocodone, and hydromorphone, including as free bases or as salts. Stabilized micronized opioid particles having a Dv90 particle size distribution of less and or equal to 10μ or less than or equal to 20μ are disclosed. Methods for micronizing an opioid to provide stabilized micronized opioid particles are also disclosed.

    摘要翻译： 公开了包含稳定的微粉化阿片样物质颗粒的新型组合物，制剂和剂型。 示例性阿片样物质包括羟考酮，羟吗啡酮，氢可酮和氢吗啡酮，包括游离碱或盐。 公开了具有小于或等于10mu或小于或等于20mu的Dv90粒度分布的稳定的微粉化阿片样物质颗粒。 还公开了使阿片样物质微粉化以提供稳定的微粉化阿片样物质颗粒的方法。

    Micronized opioid compositions having a specific particle size distribution
    3.
    发明授权
    Micronized opioid compositions having a specific particle size distribution 有权
    具有特定粒度分布的微粉化阿片样物质组合物

    公开(公告)号：US09339463B2

    公开(公告)日：2016-05-17

    申请号：US12329318

    申请日：2008-12-05

    申请人： Michael Zamloot ,  Cherng-chyi Fu ,  De-Hwa Chao ,  Andrei Blasko ,  Su Il Yum

    发明人： Michael Zamloot ,  Cherng-chyi Fu ,  De-Hwa Chao ,  Andrei Blasko ,  Su Il Yum

    IPC分类号： A61K9/14 ,  A61P25/04 ,  A61K9/16 ,  A61K31/485

    CPC分类号： A61K9/14 ,  A61K9/1623 ,  A61K9/1652 ,  A61K31/485

    摘要： Novel compositions, formulations and dosage forms comprising stabilized micronized opioid particles are disclosed. Exemplary opioids include oxycodone, oxymorphone, hydrocodone, and hydromorphone, including as free bases or as salts. Stabilized micronized opioid particles having a Dv90 particle size distribution of less and or equal to 10μ or less than or equal to 20μ are disclosed. Methods for micronizing an opioid to provide stabilized micronized opioid particles are also disclosed.

    摘要翻译： 公开了包含稳定的微粉化阿片样物质颗粒的新型组合物，制剂和剂型。 示例性阿片样物质包括羟考酮，羟吗啡酮，氢可酮和氢吗啡酮，包括游离碱或盐。 公开了具有小于或等于10μ或小于或等于20μ的Dv90粒度分布的稳定的微粉化阿片样物质颗粒。 还公开了使阿片样物质微粉化以提供稳定的微粉化阿片样物质颗粒的方法。

    FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC
    6.
    发明申请
    FILAMIN A BINDING ANTI-INFLAMMATORY AND ANALGESIC 有权
    菲林蛋白结合抗炎和毒理学

    公开(公告)号：US20140113895A1

    公开(公告)日：2014-04-24

    申请号：US14137374

    申请日：2013-12-20

    申请人： Lindsay Burns Barbier ,  Hoau-Yan Wang ,  Nan-Horng Lin ,  Andrei Blasko

    发明人： Lindsay Burns Barbier ,  Hoau-Yan Wang ,  Nan-Horng Lin ,  Andrei Blasko

    IPC分类号： C07D513/10 ,  C07D471/10 ,  C07D498/10

    CPC分类号： C07D498/10 ,  C07D471/10 ,  C07D513/10

    摘要： A compound or its pharmaceutically acceptable salt, optionally including both individual enantiomeric forms, a racemate, diastereomers and mixtures thereof, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.

    摘要翻译： 公开了可以提供止痛和减轻炎症的化合物或其药学上可接受的盐，任选地包括单独的对映体形式，外消旋物，非对映异构体及其混合物。 考虑的化合物具有对应于式A的结构，其中R基团取代基d，e，f，k，n，m，D，E，F，K，G，P，Q，W和Z被定义 中。