摘要:
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
摘要:
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
摘要:
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
摘要:
This invention provides compositions of active highly phosphorylated lysosomal sulfatase enzymes, their pharmaceutical compositions, methods of producing and purifying such lysosomal sulfatase enzymes and compositions and their use in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly lysosomal storage diseases that are caused by, or associated with, a deficiency in the lysosomal sulfatase enzyme.
摘要:
In a method and an apparatus for performing routine analyses such as polarographic or spectrophotometric analysis on a large set of sample solutions filled into separate sample cups being arranged on or shaped in a sample cup holder (101) along a moving path, wherein the samples are in consecutive cycles sucked out of the sample cup (102) by a suction tube (103) and transferred into a common vessel, wherein the analysis will be performed. The vessel (105) has a lower outlet (107) communicating with an analyzer cell (112) or the ambient space over a channel (116) which is only effective if the sample level in the vessel (105) exceeds a certain threshold level, and an aspirating mouth (108) in the upper part of the vessel (105) communicating over a valve (109) with the ambient space. The suction tube (103) has a fixed end coupled to the inlet (106) of the vessel (105) and a free end can be moved into two different working positions. A continuous suction effect is exerted on the fixed end of the suction tube during the whole series of cycles whereas the free end of the suction tube is in the first phase of each cycle moved into its first working position wherein the free end is dipping into the next sample cup and being thus positioned opposite to the suction tube and in the second phase turned into its second working position wherein the free end is protruding into the ambient space. The analysis is performed when the level of the sample in the vessel has already exceeded a prescribed threshold level and at the end of the analysis operation an overpressure is established in the vessel. Then the suction tube, as the phase of the next following cycle, is moved again into its first working position and this series of operations is cyclically repeated.
摘要:
A process is disclosed for the production of a urea-fatty acid adduct composed of discrete solid particles and having high protein and starch equivalent values wherein an aqueous solution or melt of urea at increased temperature is reacted with a fatty acid or a mixture of fatty acid and neutral fat at an increased temperature in a weight ratio of urea to fatty acid between 40 : 60 and 60 : 40 in a confined reacting space for about 2.5 to 10 seconds and wherein the mixture has been sprayed into a spraying space to allow the particles to crystallize in the air stream from the spraying.
摘要:
A selective fluoride-sensitive electrode featuring a sensor block of spherical surface compensating the effect of thermodilatation and prepared from the fluorides of a lanthanide mixture corresponding to the composition of the natural occurrents or from a mixture composed of the majority of lanthanides.
摘要:
The present invention relates to recombinant human interferon-β-1b (“IFN-β-1b”) polypeptides, or fragments, analogs, derivatives, or variants thereof, having an improved specific activity. The present invention also relates to pharmaceutical compositions comprising such IFN-β-1b polypeptides, or fragments, analogs, derivatives, or variants thereof, useful for treating multiple sclerosis. The present invention further relates to methods of producing such IFN-β-1b compositions.
摘要:
A process and apparatus for the voltammetric measurement of sample component quantities is disclosed wherein the material to be measured is passed by means of a pulsating-delivery pump into a voltammetric cell by way of a flow cross-section restriction to the surface of the voltammetric electrode, the liquid jet being adjusted such that its cross-section in the vicinity of the measuring surface of the electrode should be greater than the measurement area of the latter. The obtained voltammetric current curve is integrated at the area below the peak value, the current changing as a function of the pulsating flow rate of the liquid and the material quantities are determined from the integrated data. Preferably, the integration is effected from a value corresponding to 50% of the maximum flow rate to the maximum value and from there again down to 50% of the flow rate maximum.
摘要:
A process for recovering reusable suspended metal catalyst with a pre-determined minimum particle size from a suspension of metal particles in a liquid phase by subjecting the suspension to a continuously moving magnetic field of a minimum intensity.