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23 条记录 (耗时 0.037 秒)

    Process for the continuous production of Raney catalysts
    3.
    发明授权
    Process for the continuous production of Raney catalysts 失效
    连续生产阮内催化剂的工艺

    公开(公告)号：US3990996A

    公开(公告)日：1976-11-09

    申请号：US553486

    申请日：1975-02-27

    申请人： Sandor Gal ,  Bela Eross ,  Erno Pungor ,  Geza Siposs ,  Adorjan Monostory ,  Jozsef Barlai ,  Margit Szeiler nee Nemeth ,  Peti Nitrogenmuvek

    发明人： Sandor Gal ,  Bela Eross ,  Erno Pungor ,  Geza Siposs ,  Adorjan Monostory ,  Jozsef Barlai ,  Margit Szeiler nee Nemeth ,  Peti Nitrogenmuvek

    IPC分类号： B01J25/02 ,  B01J37/00 ,  B01J37/06 ,  B01J21/04

    CPC分类号： B01J25/02 ,  B01J37/00 ,  B01J37/06

    摘要： The invention relates to a continuous process for the preparation of Raney catalysts with controlled particle size, wherein the alloy of the catalytically active metal formed with aluminium and/or zinc is subjected to alkaline leaching, the hydrogen gas formed in this leaching step is separated and removed, the obtained product is washed, and the obtained catalyst with the desired particle size is separated. The improvement in this process comprises leaching the aluminium and/or zinc component of the alloy in a medium constantly kept in a turbulent flow, and removing the solid particles smaller than the desired range during the washing of the catalyst.The invention relates further to an apparatus for carrying out the above process, comprising a reaction chamber 1 made of one or more reactor(s) and equipped with feeding inlets 2, 3, and 4, a separator 6 equipped with a gas removing outlet 7, a tubing connecting said reaction chamber 1 to said separator 6, a washing-separating-sorting unit 9 equipped with one or more washing liquid introducing inlet(s) 10 and washing liquid removing outlet(s) 11, a tubing 8 connecting said separator 6 to said washing-separating-sorting unit 9, a storing unit 12, and a tubing 13 connecting said washing-separating-sorting unit 9 to said storing unit 12.According to the invention Raney catalysts with controlled particle size and constant characteristics can be prepared in a continuous operation.

    摘要翻译： 本发明涉及一种用于制备具有受控粒度的阮内催化剂的连续方法，其中由铝和/或锌形成的催化活性金属的合金进行碱浸，在该浸出步骤中形成的氢气被分离， 除去，将得到的产物洗涤，得到所需粒径的催化剂。 该方法的改进包括将合金的铝和/或锌组分浸入恒定保持湍流的介质中，并且在洗涤催化剂期间除去小于所需范围的固体颗粒。

    Method and an apparatus for performing routine analyses such as polarographic or spectrophotometric analysis
    4.
    发明授权
    Method and an apparatus for performing routine analyses such as polarographic or spectrophotometric analysis 失效

    公开(公告)号：US4673295A

    公开(公告)日：1987-06-16

    申请号：US850431

    申请日：1986-04-08

    申请人： Erno Pungor ,  Klara S. Toth ,  Zsofia Feher ,  Geza Nagy ,  Gyorgy Horvai

    发明人： Erno Pungor ,  Klara S. Toth ,  Zsofia Feher ,  Geza Nagy ,  Gyorgy Horvai

    IPC分类号： G01N1/00 ,  G01N27/26 ,  G01N27/28 ,  G01N35/10 ,  G01N21/00

    CPC分类号： G01N35/1083 ,  G01N2035/1086 ,  G01N27/48

    摘要： In a method and an apparatus for performing routine analyses such as polarographic or spectrophotometric analysis on a large set of sample solutions filled into separate sample cups being arranged on or shaped in a sample cup holder (101) along a moving path, wherein the samples are in consecutive cycles sucked out of the sample cup (102) by a suction tube (103) and transferred into a common vessel, wherein the analysis will be performed. The vessel (105) has a lower outlet (107) communicating with an analyzer cell (112) or the ambient space over a channel (116) which is only effective if the sample level in the vessel (105) exceeds a certain threshold level, and an aspirating mouth (108) in the upper part of the vessel (105) communicating over a valve (109) with the ambient space. The suction tube (103) has a fixed end coupled to the inlet (106) of the vessel (105) and a free end can be moved into two different working positions. A continuous suction effect is exerted on the fixed end of the suction tube during the whole series of cycles whereas the free end of the suction tube is in the first phase of each cycle moved into its first working position wherein the free end is dipping into the next sample cup and being thus positioned opposite to the suction tube and in the second phase turned into its second working position wherein the free end is protruding into the ambient space. The analysis is performed when the level of the sample in the vessel has already exceeded a prescribed threshold level and at the end of the analysis operation an overpressure is established in the vessel. Then the suction tube, as the phase of the next following cycle, is moved again into its first working position and this series of operations is cyclically repeated.

    Recombinant human interferon-beta-1b polypeptides
    7.
    发明申请
    Recombinant human interferon-beta-1b polypeptides 审中-公开
    重组人干扰素-β-1b多肽

    公开(公告)号：US20050008616A1

    公开(公告)日：2005-01-13

    申请号：US10886414

    申请日：2004-07-06

    申请人： Eirik Nestaas ,  Erno Pungor

    发明人： Eirik Nestaas ,  Erno Pungor

    IPC分类号： A61K38/00 ,  C07K14/565 ,  A61K38/21

    CPC分类号： C07K14/565 ,  A61K38/00

    摘要： The present invention relates to recombinant human interferon-β-1b (“IFN-β-1b”) polypeptides, or fragments, analogs, derivatives, or variants thereof, having an improved specific activity. The present invention also relates to pharmaceutical compositions comprising such IFN-β-1b polypeptides, or fragments, analogs, derivatives, or variants thereof, useful for treating multiple sclerosis. The present invention further relates to methods of producing such IFN-β-1b compositions.

    摘要翻译： 本发明涉及具有改善的比活性的重组人干扰素-β-1b（“IFN-β-1b”）多肽或其片段，类似物，衍生物或变体。 本发明还涉及包含可用于治疗多发性硬化症的IFN-β-1b多肽或其片段，类似物，衍生物或变体的药物组合物。 本发明还涉及产生这种IFN-β-1b组合物的方法。

    Process and apparatus for the voltammetric measurement of the quantity or mass of separated sample components
    8.
    发明授权
    Process and apparatus for the voltammetric measurement of the quantity or mass of separated sample components 失效
    用于分离样品成分的质量或质量的伏安测量的方法和装置

    公开(公告)号：US4066406A

    公开(公告)日：1978-01-03

    申请号：US677389

    申请日：1976-04-15

    申请人： Erno Pungor ,  Maria Varadi

    发明人： Erno Pungor ,  Maria Varadi

    IPC分类号： G01N27/26 ,  G01N30/64 ,  G01N27/30 ,  G01N31/08

    CPC分类号： G01N27/42 ,  G01N30/64

    摘要： A process and apparatus for the voltammetric measurement of sample component quantities is disclosed wherein the material to be measured is passed by means of a pulsating-delivery pump into a voltammetric cell by way of a flow cross-section restriction to the surface of the voltammetric electrode, the liquid jet being adjusted such that its cross-section in the vicinity of the measuring surface of the electrode should be greater than the measurement area of the latter. The obtained voltammetric current curve is integrated at the area below the peak value, the current changing as a function of the pulsating flow rate of the liquid and the material quantities are determined from the integrated data. Preferably, the integration is effected from a value corresponding to 50% of the maximum flow rate to the maximum value and from there again down to 50% of the flow rate maximum.

    Methods for high purity chromatographic separation of proteins having EGF-like binding domains
    10.
    发明授权
    Methods for high purity chromatographic separation of proteins having EGF-like binding domains 失效
    高纯度色谱分离具有EGF样结合结构域的蛋白质的方法

    公开(公告)号：US5378816A

    公开(公告)日：1995-01-03

    申请号：US991800

    申请日：1992-12-16

    申请人： Erno Pungor ,  Les Johnson ,  Monica R. Foermer

    发明人： Erno Pungor ,  Les Johnson ,  Monica R. Foermer

    IPC分类号： A61K38/00 ,  C07K1/18 ,  C07K14/745 ,  A61K37/00

    CPC分类号： C07K1/18 ,  C07K14/7455 ,  A61K38/00

    摘要： Proteins having an epidermal growth factor-like binding region, such as thrombomodulin, may be recovered and purified on a anion exchange resin, such as a polyethyleneimine resin. Conditioned medium containing recombinantly produced protein is applied to the resin under conditions of pH and ionic strength selected to result in specific binding of the protein to the resin. The column is then washed to remove non-bound proteins and bound proteins other than the desired protein to be separated. The desired protein is then eluted from the column and collected in a medium. Further purification, concentration, and other treatment of the protein may be performed by conventional techniques.

    摘要翻译： 具有表皮生长因子样结合区域的蛋白质，例如血栓调节蛋白，可以在阴离子交换树脂如聚乙烯亚胺树脂上回收和纯化。 将含有重组产生的蛋白质的条件培养基在pH和离子强度的条件下施加到树脂上，导致蛋白质与树脂的特异性结合。 然后洗涤柱以除去未分离的所需蛋白质以外的未结合的蛋白质和结合的蛋白质。 然后将所需的蛋白质从柱中洗脱并收集在培养基中。 蛋白质的进一步纯化，浓缩和其它处理可以通过常规技术进行。