公开(公告)号：US20050237341A1

公开(公告)日：2005-10-27

申请号：US11167882

申请日：2005-06-27

申请人： Michel Gangnet ,  Michael Kallay ,  Andrew Wu ,  Eric Stollnitz ,  Devon Strawn ,  John Lounsbery ,  Patrick Perez

发明人： Michel Gangnet ,  Michael Kallay ,  Andrew Wu ,  Eric Stollnitz ,  Devon Strawn ,  John Lounsbery ,  Patrick Perez

IPC分类号： G06T1/00 ,  G06T5/00 ,  G06T11/00 ,  G06T11/40 ,  H04N1/46 ,  H04N1/60 ,  G09G5/00

CPC分类号： G06T11/001

摘要： A system and method for generating color gradients is provided. The system generates color gradients using techniques from geometric surface modeling. The system and method of the present invention allow designers to specify very complex gradients in a simple way. The system can employ, for example, a vector-based interpolation method and/or a pixel-based partial differential equation (PDE) interpolation methods to facilitate generation of the color gradients. In one example, input boundary curves and/or feature curves are approximated by line segments, which are then utilized to generate a triangulation approximating a smooth color gradient.

摘要翻译： 提供了一种用于产生色彩渐变的系统和方法。 该系统使用几何表面建模技术生成色彩渐变。 本发明的系统和方法允许设计者以简单的方式指定非常复杂的梯度。 该系统可以采用例如基于矢量的插值方法和/或基于像素的偏微分方程（PDE）内插方法来促进颜色梯度的产生。 在一个示例中，输入边界曲线和/或特征曲线由线段近似，然后线段用于生成近似平滑颜色梯度的三角测量。

公开(公告)号：US10342623B2

公开(公告)日：2019-07-09

申请号：US14917896

申请日：2015-03-12

申请人： Justin Huelman ,  Andrew Wu ,  Michael Jung ,  Marc Child ,  Vidit Sharma ,  Addason Mccaslin ,  PROXIMED, LLC

发明人： Justin Huelman ,  Andrew Wu ,  Michael Jung ,  Marc Child ,  Vidit Sharma ,  Addason Mccaslin

IPC分类号： A61B34/20 ,  A61B17/00 ,  A61B17/42 ,  A61B90/00

摘要： Surgical systems and methods for avoiding injury to an anatomical structure are disclosed. According to some aspects, an implantable device configured to emit a detectable field may be attached to the anatomical structure. A proximity sensor may be attached to a distal end of a surgical instrument and may be configured to detect the detectable field. A control unit in communication with the proximity sensor may be configured to use the proximity sensor to determine if the distal end of the surgical instrument is within a predetermined distance of the implantable device. If so, a notification such as a vibration or alarm may be provided to a user of the surgical instrument so that the user can maneuver the surgical instrument to limit or prevent contact with the anatomical structure.

公开(公告)号：US20170202617A1

公开(公告)日：2017-07-20

申请号：US15478113

申请日：2017-04-03

申请人： Denise Zarins ,  Andrew Wu ,  Hanson Gifford, III ,  Mark Deem ,  Mark Gelfand ,  Howard R. Levin

发明人： Denise Zarins ,  Andrew Wu ,  Hanson Gifford, III ,  Mark Deem ,  Mark Gelfand ,  Howard R. Levin

IPC分类号： A61B18/14 ,  A61M5/172 ,  A61N1/40 ,  A61N7/02 ,  A61F7/12 ,  A61N1/36

CPC分类号： A61B18/1492 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61F7/123 ,  A61F2007/126 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2210/1082 ,  A61N1/28 ,  A61N1/32 ,  A61N1/326 ,  A61N1/36007 ,  A61N1/36017 ,  A61N1/36114 ,  A61N1/36117 ,  A61N1/3627 ,  A61N1/403 ,  A61N5/045 ,  A61N7/02 ,  A61N2007/003

摘要： Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. In some embodiments, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy.

公开(公告)号：US20160220314A1

公开(公告)日：2016-08-04

申请号：US14917896

申请日：2015-03-12

申请人： Justin HUELMAN ,  Andrew WU ,  Michael JUNG ,  Marc CHILD ,  Vidit SHARMA ,  Addason MCCASLIN ,  PROXIMED, LLC

发明人： Justin Huelman ,  Andrew Wu ,  Michael Jung ,  Marc Child ,  Vidit Sharma ,  Addason Mccaslin

IPC分类号： A61B34/20

CPC分类号： A61B34/20 ,  A61B2017/00022 ,  A61B2017/00119 ,  A61B2017/00876 ,  A61B2017/4216 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3954 ,  A61B2562/0223 ,  A61B2562/0257

摘要： Surgical systems and methods for avoiding injury to an anatomical structure are disclosed. According to some aspects, an implantable device configured to emit a detectable field may be attached to the anatomical structure. A proximity sensor may be attached to a distal end of a surgical instrument and may be configured to detect the detectable field. A control unit in communication with the proximity sensor may be configured to use the proximity sensor to determine if the distal end of the surgical instrument is within a predetermined distance of the implantable device. If so, a notification such as a vibration or alarm may be provided to a user of the surgical instrument so that the user can maneuver the surgical instrument to limit or prevent contact with the anatomical structure.

摘要翻译： 公开了用于避免对解剖结构的损伤的手术系统和方法。 根据一些方面，构造成发射可检测区域的可植入装置可以附接到解剖结构。 接近传感器可以附接到手术器械的远端，并且可以被配置为检测可检测的场。 与接近传感器通信的控制单元可以被配置为使用接近传感器来确定外科器械的远端是否在可植入装置的预定距离内。 如果是这样，可以向外科器械的使用者提供诸如振动或警报的通知，使得用户能够操纵外科器械来限制或阻止与解剖结构的接触。

公开(公告)号：US09345900B2

公开(公告)日：2016-05-24

申请号：US12147191

申请日：2008-06-26

申请人： Andrew Wu ,  Benjamin J. Clark ,  Erik Thai ,  Nicolas Zadno ,  Denise Zarins

发明人： Andrew Wu ,  Benjamin J. Clark ,  Erik Thai ,  Nicolas Zadno ,  Denise Zarins

IPC分类号： A61F7/00 ,  A61F7/12 ,  A61F2/00 ,  A61N1/40 ,  A61B18/14 ,  A61N1/05 ,  A61N1/36 ,  A61N1/06 ,  A61B18/00 ,  A61B18/12 ,  A61B18/18 ,  A61B19/00 ,  A61B17/00 ,  A61B17/22 ,  A61F7/10 ,  A61N5/06 ,  A61N7/02 ,  A61N7/00

CPC分类号： A61B18/1233 ,  A61B18/12 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1492 ,  A61B18/1815 ,  A61B90/39 ,  A61B2017/00084 ,  A61B2017/22054 ,  A61B2017/22068 ,  A61B2018/00023 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00261 ,  A61B2018/00279 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00636 ,  A61B2018/00666 ,  A61B2018/00702 ,  A61B2018/00714 ,  A61B2018/00755 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00994 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/144 ,  A61B2018/1475 ,  A61F7/007 ,  A61F7/10 ,  A61F7/12 ,  A61F2007/0056 ,  A61F2007/0075 ,  A61F2007/126 ,  A61N1/0558 ,  A61N1/057 ,  A61N1/06 ,  A61N1/36007 ,  A61N1/36017 ,  A61N1/403 ,  A61N5/0601 ,  A61N5/0622 ,  A61N7/02 ,  A61N7/022 ,  A61N2005/0612 ,  A61N2007/0026 ,  A61N2007/003

摘要： Methods and system are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. In some embodiments, thermally-induced renal neuromodulation is achieved via delivery of a pulsed thermal therapy.

摘要翻译： 提供热诱导肾神经调节的方法和系统。 热诱导的肾神经调节可以通过直接和/或通过间接施加热能来加热或冷却有助于肾功能的神经纤维或者供给或灌注神经纤维的血管结构来实现。 在一些实施例中，神经纤维，非目标组织或热能递送元件的参数可以经由一个或多个传感器来监测，以控制热诱导的神经调节。 在一些实施方案中，可以提供保护元件以减少在非靶组织中诱导的热损伤程度。 在一些实施方案中，热诱导的肾神经调节通过脉冲热疗法的递送来实现。

公开(公告)号：US08956352B2

公开(公告)日：2015-02-17

申请号：US13281395

申请日：2011-10-25

申请人： Kevin Mauch ,  Mario Alvarado ,  Robert Beetel ,  William Chang ,  Justin Goshgarian ,  Leonila Rivera ,  Sukyoung Shin ,  Michele Silver ,  Sina Som ,  Andrew Wu ,  Denise Zarins ,  Juanita Sanchez-Cole ,  Maria G. Aboytes

发明人： Kevin Mauch ,  Mario Alvarado ,  Robert Beetel ,  William Chang ,  Justin Goshgarian ,  Leonila Rivera ,  Sukyoung Shin ,  Michele Silver ,  Sina Som ,  Andrew Wu ,  Denise Zarins ,  Juanita Sanchez-Cole ,  Maria G. Aboytes

IPC分类号： A61B18/14 ,  A61B18/04 ,  A61B18/18 ,  A61B18/00 ,  A61M25/00 ,  A61M25/01

CPC分类号： A61B18/1492 ,  A61B2018/00023 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00505 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61M25/0041 ,  A61M25/0074 ,  A61M25/0133 ,  A61M25/0138 ,  A61M25/0147

摘要： Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device having a multi-electrode array configured to be delivered to a renal blood vessel. The array is selectively transformable between a delivery or low-profile state (e.g., a generally straight shape) and a deployed state (e.g., a radially expanded, generally helical shape). The multi-electrode array is sized and shaped so that the electrodes or energy delivery elements contact an interior wall of the renal blood vessel when the array is in the deployed (e.g., helical) state. The electrodes or energy delivery elements are configured for direct and/or indirect application of thermal and/or electrical energy to heat or otherwise electrically modulate neural fibers that contribute to renal function or of vascular structures that feed or perfuse the neural fibers.

摘要翻译： 本文公开了通过血管内通路实现肾脏神经调节的导管装置，系统和方法。 例如，本技术的一个方面涉及具有被配置为输送到肾血管的多电极阵列的治疗装置。 阵列可以在传送或低轮廓状态（例如，大致直线形状）和展开状态（例如，径向膨胀，大致螺旋形状）之间选择性地变换。 多电极阵列的尺寸和形状使得当阵列处于部署（例如螺旋状态）时，电极或能量递送元件接触肾血管的内壁。 电极或能量输送元件构造成用于直接和/或间接施加热和/或电能以加热或以其他方式电调节有助于肾功能的神经纤维或者供给或灌注神经纤维的血管结构。

公开(公告)号：US20130296767A1

公开(公告)日：2013-11-07

申请号：US13868426

申请日：2013-04-23

申请人： Denise Zarins ,  Hanson Gifford, III ,  Mark Deem ,  Nicolas Zadno ,  Benjamin J. Clark ,  Andrew Wu ,  Kenneth J. Michlisch

发明人： Denise Zarins ,  Hanson Gifford, III ,  Mark Deem ,  Nicolas Zadno ,  Benjamin J. Clark ,  Andrew Wu ,  Kenneth J. Michlisch

IPC分类号： A61B18/14 ,  A61B18/12

CPC分类号： A61B18/1492 ,  A61B18/1206 ,  A61B18/18 ,  A61B2018/00023 ,  A61B2018/00077 ,  A61B2018/0016 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00648 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/124 ,  A61B2018/1435 ,  A61B2018/1465 ,  A61N1/0551 ,  A61N1/32 ,  A61N1/327 ,  A61N1/36007 ,  A61N7/022

摘要： Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided.

摘要翻译： 提供了用于不间断地周围处理体腔的方法和装置。 装置可以定位在患者的体腔内，并且可以在第一纵向和角位置处递送能量，以在第一位置处产生小于整个圆周的处理区域。 该装置还可以在体腔内的一个或多个附加的纵向和角度位置处递送能量，以在一个或多个附加位置处创建小于整个圆周处理区域，该一个或多个附加位置从第一处理区域纵向和角度偏移 。 第一处理区和一个或多个另外的处理区的叠置限定非连续的圆周处理区，而不形成连续的周向损伤。 提供了用于实现这种非连续圆周处理的方法和装置的各种实施例。

公开(公告)号：US20100220421A1

公开(公告)日：2010-09-02

申请号：US12776668

申请日：2010-05-10

申请人： Andrew Wu

发明人： Andrew Wu

IPC分类号： H02H9/02

CPC分类号： H02M3/1588 ,  H02M1/32 ,  H02M2001/0009 ,  Y02B70/1466

摘要： A regulator with a high side pass device and a low side pass device coupled in series to the high side pass device is disclosed. The apparatus further includes a control module coupled to the high side pass device and the low side pass device. The control module is coupled to the high side pass device and the low side pass device to control the high side pass device and the low side pass device. The control module is operable to lock out the high side pass device under certain conditions.

公开(公告)号：US20100168739A1

公开(公告)日：2010-07-01

申请号：US12495691

申请日：2009-06-30

申请人： Andrew Wu ,  Benjamin J. Clark ,  Denise Zarins ,  Erik Thai

发明人： Andrew Wu ,  Benjamin J. Clark ,  Denise Zarins ,  Erik Thai

IPC分类号： A61B18/18 ,  A61B18/02 ,  A61B18/04 ,  A61H1/00

CPC分类号： A61B18/1492 ,  A61B2017/00212 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00702 ,  A61B2018/00797 ,  A61B2018/00821 ,  A61B2018/00875 ,  A61N2007/003

摘要： Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.

公开(公告)号：US20090271762A1

公开(公告)日：2009-10-29

申请号：US12432086

申请日：2009-04-29

申请人： Jacob Taylor ,  Lila Alexei Tretikov ,  Majed Itani ,  Joseph Parsons ,  Travis Swicegood ,  Matt Heitzenroder ,  Andrew Wu ,  Roger Smith ,  John Mertic

发明人： Jacob Taylor ,  Lila Alexei Tretikov ,  Majed Itani ,  Joseph Parsons ,  Travis Swicegood ,  Matt Heitzenroder ,  Andrew Wu ,  Roger Smith ,  John Mertic

IPC分类号： G06F9/44 ,  G06F3/00

CPC分类号： G06F21/6227 ,  G06F2221/2101 ,  G06Q10/10

摘要： A business software application system and method are provided.

摘要翻译： 提供商业软件应用系统和方法。